PT J
AU Mohanty, S
   Panigrahi, MK
   Turuk, J
   Dhal, S
AF Mohanty, Srujana
   Panigrahi, Manas Kumar
   Turuk, Jyotirmayee
   Dhal, Sagarika
TI Liver Abscess due to Streptococcus constellatus in an Immunocompetent Adult: A Less Known Entity
SO JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
LA English
DT Article
DE Liver abscess; Hepatic abscess; Pyogenic liver abscess; Streptococcus constellatus
ID anginosus; milleri; trends
AB Background: Pyogenic liver abscesses (PLAs) are an uncommon, but potentially life threatening infection. We report a case of PLA due to Streptococcus constellatus, a member of the Streptococcus anginosus group (SAG) bacteria. commonly found as commensals of the oropharyngeal, gastrointestinal and genitourinary flora. Case: The patient, a 42-year-old man with no premorbidities, non-smoker and non-alcoholic, presented to our hospital with high-grade fever associated with chills and rigors and right upper quadrant pain of one month duration. Culture of the ultrasound-guided liver aspirate yielded a pure growth of S. constellatus subspecies constellatus identified by conventional biochemical tests. In a standard antimicrobial disk-diffusion test, the isolate was susceptible to cefepime, cefotaxime, ceftriaxone, vancomcyin, levofioxacin, clindamycin and linezolid. Treatment with parenteral ceftriaxone alongwith appropriate surgical management led to resolution of the abscess with no recurrence of infection at three months follow-up. Conclusions: The pathogenic potential of SAG has generally been disregarded because of the commensal nature of these microorganisms: however, streptococci belonging to this group have been increasingly reported as relevant pathogens in abscesses and blood cultures. An underlying condition, such as diabetes, cirrhosis or cancer or some medical manipulation, such as dental extraction, acupuncture, or hemorrhoidectomy is associated with the majority of patients with SAG abscess. However, the present case highlights the need to include S. constellatus and other members of the SAG while investigating for etiology of PLA, even in immunocompetent adults.
C1 [Mohanty, Srujana; Turuk, Jyotirmayee; Dhal, Sagarika] All India Inst Med Sci, Dept Microbiol, Bhubaneswar 751019, Odisha, India.
   [Panigrahi, Manas Kumar] All India Inst Med Sci, Dept Gastroenterol, Bhubaneswar 751019, Odisha, India.
C3 All India Institute of Medical Sciences (AIIMS) Bhubaneswar; All India Institute of Medical Sciences (AIIMS) Bhubaneswar
RP Mohanty, S (corresponding author), All India Inst Med Sci, Dept Microbiol, Bhubaneswar 751019, Odisha, India.
EM srujana_micro@yahoo.co.in
CR Unknown -, 2016, CLINICAL PRACTICE GUIDELINE: POSTPARTUM HAEMORRHAGE, V0, P1
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NR 26
TC 17
Z9 21
U1 0
U2 3
PU NATL MED ASSOC
PI WASHINGON
PA 1012 10TH ST, N W, WASHINGON, DC 20001 USA
SN 0027-9684
EI 1943-4693
J9 J NATL MED ASSOC
JI J. Natl. Med. Assoc.
PD DEC 15
PY 2018
VL 110
IS 6
BP 591
EP 595
DI 10.1016/j.jnma.2018.03.006
PG 5
WC Medicine, General & Internal
SC General & Internal Medicine
GA HA2SB
UT WOS:000450091500014
PM 30129495
DA 2026-01-16
ER

PT J
AU Stoerkel, E
   Bellanti, D
   Paat, C
   Peacock, K
   Aden, J
   Setlik, R
   Walter, J
   Inman, A
AF Stoerkel, Erika
   Bellanti, Dawn
   Paat, Charmagne
   Peacock, Kimberly
   Aden, James
   Setlik, Robert
   Walter, Joan
   Inman, Alice
TI Effectiveness of a Self-Care Toolkit for Surgical Breast Cancer Patients in a Military Treatment Facility
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Article
DE self-care; mind-body skills; breast cancer; surgery; pain; anxiety
ID quality-of-life; stress reduction; mindfulness; intervention; relaxation; inflammation; therapy; symptoms; distress; program
AB Objective: To assess whether a self-care toolkit (SCT) provided to breast cancer patients undergoing surgery could mitigate distress and lessen symptoms associated with surgery. Design: One hundred women with breast cancer, planning to undergo initial surgery, were randomly assigned to either one of two groups: treatment as usual (TAU; n=49) or TAU with the addition of an SCT (n=51). The SCT contained an MP3 player with audio-files of guided mind-body techniques (breathing, progressive muscle relaxation, meditation, guided imagery, and self-hypnosis) and acupressure antinausea wristbands. Anxiety, pain, nausea, sleep, fatigue, global health, and quality of life (QOL) were assessed using validated outcome measures. Two inflammatory blood markers (erythrocyte sedimentation rate [ESR] and C-reactive protein [CRP]) were measured serially. Data were collected at baseline (T1), immediately before surgery (T2), within 10h postoperatively (T3), and approximate to 2 weeks postsurgery (T4). Settings: Numerous studies have shown that psychological distress associated with a cancer diagnosis can affect pain perception and QOL. Results: Between T1 and T4, there were significant between-group differences in Patient-Reported Outcomes Measurement Information System (PROMIS)-57 scores of Pain Interference, Fatigue, and Satisfaction with Social Roles, favoring the SCT group compared with TAU (p=0.005, p=0.023, and p=0.021, respectively). There was a significant mean change in Defense and Veterans Pain Rating Scale (DVPRS) scores from T2 to T3, with the SCT group having significantly smaller increases in postoperative pain (p=0.008) and in postoperative ESR (p=0.0197) compared with the TAU group. Clinically significant reductions in anxiety occurred in the SCT group during the main intervention period. Conclusion: These results suggest that using the SCT in the perioperative period decreased pain perceptions, fatigue, and inflammatory cytokine secretion.
C1 [Stoerkel, Erika; Bellanti, Dawn; Paat, Charmagne] Thought Leadership & Innovat Fdn, 1750 Tysons Blvd,Suite 1500, Mclean, VA 22102 USA.
   [Peacock, Kimberly] Univ Texas Hlth San Antonio, Dept Epidemiol & Biostat, San Antonio, TX USA.
   [Aden, James; Setlik, Robert; Inman, Alice] Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA.
   [Walter, Joan] Samueli Inst, Alexandria, VA USA.
C3 University of Texas System; University of Texas at San Antonio; United States Department of Defense; United States Army; Brooke Army Medical Center
RP Stoerkel, E (corresponding author), Thought Leadership & Innovat Fdn, 1750 Tysons Blvd,Suite 1500, Mclean, VA 22102 USA.
EM erika.l.stoerkel@gmail.com
FU U.S. Army Medical Research and Materiel Command [W81XWH-11-1-0538]; U.S. Army Medical Research Acquisition Activity,Chandler Street, Fort Detrick MD
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NR 36
TC 25
Z9 28
U1 0
U2 22
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD SEP 15
PY 2018
VL 24
IS 9-10
BP 916
EP 925
DI 10.1089/acm.2018.0069
PG 10
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GU6VP
UT WOS:000445455600009
PM 30247967
DA 2026-01-16
ER

PT J
AU Rahman, A
   Rahman, R
   Macrinici, G
   Li, S
AF Rahman, Abed
   Rahman, Raed
   Macrinici, George
   Li, Sam
TI Low Volume Neurolytic Retrocrural Celiac Plexus Block for Visceral Cancer Pain: Retrospective Review of 507 Patients with Severe Malignancy Related Pain Due to Primary Abdominal Cancer or Metastatic Disease
SO PAIN PHYSICIAN
LA English
DT Review
DE Celiac plexus; neurolytic; abdominal cancer pain; pain; retrocrural; cancer pain
ID splanchnic nerve neurolysis; quality-of-life; pancreatic-cancer; management; relief; acupuncture; alcohol
AB Background: Abdominal pain from primary cancer or metastatic disease is a significant cause of pain for patients undergoing treatment for the disease. Patient's pain may be resistant to conventional analgesics. The need for timely pain relief in order to facilitate further care in the cancer treatment plan should be a priority. Objectives: The aim of this retrospective observational review was to assess the relief given with a low volume neurolytic retrocrural celiac plexus nerve block, the duration of the procedure, the duration of relief, the reduction in daily opioid consumption, and the improvement of quality of life in a patient suffering from incapacitating abdominal pain due to primary abdominal malignancy or abdominal metastatic disease. Patients were given a neurolytic celiac plexus block without previous diagnostic block due to multiple comorbidities. Study Design: This is a retrospective, observational study. Methods: Five hundred and seven patients were studied and data at 5 months for 455 patients were retained at the end of the review. They were evaluated in the pain center prior to and after the neurolytic retrocrural celiac plexus nerve block under fluoroscopic guidance. They were assessed on duration of procedure, pain scores (numeric rating scale 0-10), daily opioid consumption, quality of life improvement (simple yes or no question at 3 months) and routine follow-up during treatment for the cancer for 6 months or end of life. All data was gathered by extensive chart review and placed on a spreadsheet for analysis. Results: Follow-up was completed 6 months after the procedure. Pain scores, daily opioid consumption, and quality of life showed improvement for the duration of the study. There was some return in pain during the fourth to sixth month due to disease progression and the anticipated duration of the neurolytic agent. Some short duration known side effects did occur. An initial vascular contrast uptake of 6.7% was noted during the procedure while utilizing digital subtraction angiography with fluoroscopy. Limitations: A larger sample size would be ideal, as well as, a prospective trial with a control group, but this is unrealistic in our patient population. A proven quality of life questionnaire would be beneficial. Comparing alcohol, phenol and radiofrequency thermocoagulation would be interesting to equate duration, effect, and side effects. Conclusion: Low volume neurolytic retrocrural celiac plexus nerve block with phenol is a safe procedure providing up to 6 months of pain relief and is an effective, well-established, minimally time-consuming procedure for abdominal pain due to primary malignancy or metastatic spread.
C1 [Rahman, Abed; Rahman, Raed; Macrinici, George] Midwestern Reg Med Ctr, Dept Pain Med, Intervent Pain Management, 2520 Elisha Ave, Zion, IL 60099 USA.
   [Li, Sam] JHS Hosp Cook Cty, Dept Anesthesiol & Pain Management, Chicago, IL USA.
C3 John H Stroger Junior Hospital Cook County
RP Rahman, A (corresponding author), Midwestern Reg Med Ctr, Dept Pain Med, Intervent Pain Management, 2520 Elisha Ave, Zion, IL 60099 USA.
EM Abed.rahman@ctca-hope.com
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NR 26
TC 11
Z9 13
U1 0
U2 2
PU AM SOC INTERVENTIONAL PAIN PHYSICIANS
PI PADUCAH
PA 81 LAKEVIEW DR, PADUCAH, KY 42001 USA
SN 1533-3159
EI 
J9 PAIN PHYSICIAN
JI Pain Physician
PD SEP-OCT 15
PY 2018
VL 21
IS 5
BP 497
EP 504
DI 
PG 8
WC Anesthesiology; Clinical Neurology
SC Anesthesiology; Neurosciences & Neurology
GA GV1AY
UT WOS:000445800200020
PM 30282394
DA 2026-01-16
ER

PT J
AU Lin, YP
   Li, YJ
   Chen, BL
   Guo, YH
AF Lin, Yong-Peng
   Li, Yong-Jin
   Chen, Bo-Lai
   Guo, Yu-Hai
TI Lumbar laminotomy and replantation for the treatment of adult spinal epidermoid cyst A case report
SO MEDICINE
LA English
DT Article
DE lumbar laminotomy and replantation; spinal epidermoid cysts; spinal tumor; surgical treatment regimen
ID plate fixation; region
AB Rationale: Adult spinal epidermoid cyst (SEC) is a rare tumor. Lumbar laminectomy and tumor removal was a routine surgical procedure for adult spinal epidermoid cyst according to the literature, but postoperative lumbar instability and intractable low back pain may occur. In this study, we presented a brief report of an adult lumbar epidermoid cyst and introduced another surgical approach. Patient concerns: This 28-year-old woman has been complaining of the severe right buttock pain and right thigh radiating pain for half a year. She had been diagnosed as sacroiliitis, spinal arthritis, and lumbar disc herniation at 3 different hospitals before coming to our hospital. And she received a variety of conservative treatments, including non-steroidal anti-inflammatory drugs, aspirin, acetaminophen, glucocorticoids, acupuncture, physical therapy, and so on. However, her pain did not diminish at all. Finally, we find a space-occupying lesion in her lumbar magnetic resonance images (MRI). The lesion was slightly low, equal, and uneven equal-low signals on T1WI. T2WI showed slightly higher, equal, and uneven equal-high signals. And a thin-rim enhancement was observed on Gd-DTPA-enhanced MRI. Diagnoses: Adult spinal epidermoid cyst. Interventions: The patient underwent a surgery of lumbar laminectomy, tumor excision, and spinous process-vertebral plate in situ replantation. Outcomes:Postoperative pathology prompted that the tumor was cystoid. The patient's symptoms were completely removed 1 week after surgery. Three-month postoperative MRI confirmed that the spinal epidermoid cyst had been completely removed and three-dimensional CT prompted lumbar lamina in situ. Bony fusion occurred at 6 months after the surgery. Lessons:Lumbar laminotomy and replantation provides an ideal option to treat adult spinal epidermoid cyst because it can completely remove the cyst and simultaneously reduce the risk of iatrogenic lumbar instability.
C1 [Lin, Yong-Peng; Li, Yong-Jin; Chen, Bo-Lai; Guo, Yu-Hai] Guangzhou Univ Chinese Med, Guangdong Prov Hosp Chinese Med, Affiliated Hosp 2, Guangzhou, Guangdong, Peoples R China.
C3 Guangzhou University of Chinese Medicine
RP Chen, BL (corresponding author), Inpatient 10th Floor,111 Dade Rd, Guangzhou, Guangdong, Peoples R China.
EM chenbolai337@163.com
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NR 16
TC 6
Z9 7
U1 0
U2 4
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD JAN 15
PY 2018
VL 97
IS 1
BP 
EP 
DI 10.1097/MD.0000000000009334
PG 4
WC Medicine, General & Internal
SC General & Internal Medicine
GA FU8CQ
UT WOS:000424080300011
PM 29505514
DA 2026-01-16
ER

PT J
AU Ruela, LO
   Iunes, DH
   Nogueira, DA
   Stefanello, J
   Gradim, CVC
AF Ruela, Ludmila de Oliveira
   Iunes, Denise Hollanda
   Nogueira, Denismar Alves
   Stefanello, Juliana
   Gradim, Clícia Valim Côrtes
TI Effectiveness of auricular acupuncture in the treatment of cancer pain:
SO Revista da Escola de Enfermagem da U S P
LA spa
DT Journal Article
AB OBJECTIVE: To evaluate the effectiveness of auricular acupuncture in the pain of  cancer patients receiving chemotherapy and to verify if there were alterations in  the use of analgesics after the application of this intervention. METHOD:  Randomized controlled trial with cancer patients with complaints of pain greater  than or equal to four in the Numerical Pain Scale. Two parallel groups were  created, an Experimental group, which received auricular acupuncture at energy  balance points and at points indicated for the treatment of pain, and a Placebo  group, in which fixed placebo points were used. Both groups received the  application of semipermanent needles in eight sessions. RESULTS: 31 cancer  patients participated in the study. After the eight auricular acupuncture  sessions, there was a significant difference between the groups regarding the  reduction of pain intensity (p < 0.001) and of the use of medications (p < 0.05).  CONCLUSION: Auricular acupuncture was effective in reducing the pain of patients  receiving chemotherapy. Brazilian Registry of Clinical Trials: RBR-6k3rqh.
C1 Universidade Federal de Alfenas, Escola de Enfermagem, Alfenas, MG, Brasil.
   Universidade Federal de Alfenas, Instituto Ciências da Motricidade. Alfenas, MG, Brasil.
   Universidade Federal de Alfenas, Instituto de Ciências Exatas, Departamento de Estatística, Alfenas, MG, Brasil.
   Universidade de São Paulo, Escola de Enfermagem de Ribeirão Preto, Departamento Materno-Infantil e Saúde Pública, Ribeirão Preto, SP, Brasil.
   Universidade Federal de Alfenas, Escola de Enfermagem, Alfenas, MG, Brasil.
NR 0
TC 0
SN 
EI 0080-623
J9 Rev Esc Enferm USP
PD DEC 21
PY 2018
VL 52
IS 
BP e03402
EP e03402
DI 10.1590/S1980-220X2017040503402
PG 1
WC Acupuncture, Ear; methods; Adult; Aged; Analgesics; administration & dosage; Antineoplastic Agents; administration & dosage; Brazil; Cancer Pain; therapy; Female; Humans; Male; Middle Aged; Neoplasms; drug therapy; Pain Measurement; Treatment Outcome
UT PubMed:30570087
PM 30570087
DA 2018-12-21
ER

PT J
AU Oh, PJ
   Kim, YL
AF Oh, Pok Ja
   Kim, You Lim
TI [Effectiveness of Non-Pharmacologic Interventions in Chemotherapy Induced
SO Journal of Korean Academy of Nursing
LA kor
DT Journal Article
DE Chemotherapy, Adjuvant; Meta-analysis; Peripheral Nervous System Diseases
AB PURPOSE: This study was conducted to evaluate the effectiveness of  non-pharmacologic interventions in chemotherapy-induced peripheral neuropathy  (CIPN). METHODS: PubMed, Cochrane Library CENTRAL, EMBASE, CINAHL, and several  Korean databases (Until August 2017) were searched. The main search strategy  combined terms for peripheral neuropathy and presence of neoplasms. The risk of  bias was assessed using the Cochrane's Risk of Bias tool for randomized studies  and the Risk of Bias Assessment tool for non-randomized studies. To estimate the  effect size, a meta-analysis of the studies was performed using the Rev Man 5.3  program of the Cochrane Library random-effects models were used in the analyses.  RESULTS: Twenty-two studies with a total of 954 participants met the inclusion  criteria. Of the 22 studies, 12 were used to estimate the effect size of the  non-pharmacologic interventions. The non-pharmacologic interventions used in  patients with CIPN were exercise, acupuncture, massage, and foot bath. The  acupuncture significantly reduced CIPN symptoms and signs (d=-0.71) and CIPN pain  (d=-0.73) (p<.001). Massage and foot bath were also effective in reducing CIPN  symptoms (d=-0.68; 95% CI=-1.05, -0.30; p<.001; I²=19%).Exercises were effective  in improving muscle strength and endurance(d=-0.55) and quality of life  (d=-2.96), but they were not significantly effective in improving CIPN.  CONCLUSION: Although these results provide little evidence of the effectiveness  of acupuncture, massage, and foot bath in the treatment of CIPN, they suggest  that these interventions can reduce CIPN symptoms in patients with cancer.  However, the findings of this study should be interpreted with caution as there  is a relative lack of data in this field, and additional well-designed studies  are needed. PROSPERO registration: CRD42017076278.
C1 Department of Nursing, Sahmyook University, Seoul, Korea.
   Department of Physical Therapy χ Laboratory of Rehabilitation & Health Science, Sahmyook University, Seoul, Korea. youlimy81@naver.com.
NR 0
TC 0
SN 2093-758
EI 
J9 J Korean Acad Nurs
PD MAY 8
PY 2018
VL 48
IS 2
BP 123
EP 142
DI 10.4040/jkan.2018.48.2.123
PG 19
WC Acupuncture Therapy; Antineoplastic Agents; adverse effects; Baths; Databases, Factual; Exercise; Humans; Massage; Neoplasms; drug therapy; Peripheral Nervous System Diseases; etiology; Quality of Life
UT PubMed:29735874
PM 29735874
DA 2018-05-08
ER

PT J
AU Eriksen, WT
   Singerman, L
   Romero, SAD
   Bussell, J
   Barg, FK
   Mao, JJ
AF Eriksen, Whitney T.
   Singerman, Lydia
   Romero, Sally A. D.
   Bussell, Jason
   Barg, Frances K.
   Mao, Jun J.
TI Understanding the Use of Acupuncture for Insomnia Among Cancer Survivors: A Qualitative Study
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Article
DE acupuncture; insomnia; knowledge; belief; cancer; qualitative research
ID cognitive-behavioral therapy; alternative medicine; complementary; options; trial; prevalence; fatigue; pain
AB Objective: To understand cancer survivors' perceptions regarding the use of acupuncture for the treatment of cancer-related insomnia. Design: Semistructured interviews with cancer survivors participating in a randomized controlled trial comparing the effectiveness of Cognitive Behavioral Therapy for Insomnia (CBT-I) and acupuncture for the treatment of insomnia. Interviews were conducted before randomization into either treatment option, and structured to elicit participants' experiences with insomnia as well as their beliefs and understanding surrounding acupuncture for the treatment of insomnia. An integrated approach was used for data analysis. Subjects: Sixty-three cancer survivors with DSM-V diagnosed insomnia. Results: Participants shared a broad lack of understanding regarding acupuncture for the treatment of insomnia. Specifically, individuals in this study expressed confusion surrounding what symptoms or medical conditions acupuncture could be used to treat, how acupuncture works, and how long the effects of acupuncture last. Conclusions: This study identified three specific gaps in knowledge, including treatment target, mechanism, and durability, surrounding the use of acupuncture for insomnia in cancer survivors. Addressing these gaps by providing appropriate and timely education surrounding the use of acupuncture to treat insomnia is essential to increase the evidence-informed utilization of acupuncture and to better meet patients' needs among cancer survivors.
C1 [Eriksen, Whitney T.; Barg, Frances K.] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.
   [Singerman, Lydia] Rutgers New Jersey Med Sch, Newark, NJ USA.
   [Romero, Sally A. D.; Bussell, Jason; Mao, Jun J.] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA.
C3 University of Pennsylvania; Rutgers University System; Rutgers University New Brunswick; Rutgers University Biomedical & Health Sciences; Memorial Sloan Kettering Cancer Center
RP Mao, JJ (corresponding author), Mem Sloan Kettering Canc Ctr, Bendheim Integrat Med Ctr, 1429 First Ave, New York, NY 10021 USA.
EM maoj@mskcc.org
FU Patient-Centered Outcomes Research Institute (PCORI) award [CER-1403-14292]; National Cancer Institute of the National Institutes of Health [2P30CA016520-40]; Memorial Sloan Kettering Cancer Center [3P30CA008748-50, R25CA020449]; National Cancer Institute [R25CA020449, P30CA008748, P30CA016520] Funding Source: NIH RePORTER
CR Asnis GM, 2016, INT J MOL SCI, V17, P0, DOI 10.3390/ijms17010050
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   White Adrian, 2004, ACUPUNCT MED, V22, P122
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NR 32
TC 14
Z9 16
U1 0
U2 63
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD SEP 15
PY 2018
VL 24
IS 9-10
BP 962
EP 967
DI 10.1089/acm.2018.0156
PG 6
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GU6VP
UT WOS:000445455600014
PM 30247951
DA 2026-01-16
ER

PT J
AU Federman, DG
   Holleck, JL
AF Federman, Daniel G
   Holleck, Jurgen L
TI Auricular Acupuncture and Skin-Cancer Detection: An Opportunity.
SO Medical acupuncture
LA English
DT Journal Article
DE auricular acupuncture; basal-cell carcinoma; squamous-cell carcinoma
AB Background: Auricular acupuncture is effective for many patients with pain. Many  skin malignancies and precancerous lesions are found on the head and neck.  Practitioners of acupuncture are in a unique situation to detect cutaneous  malignancy at an early state. Case: An 83-year-old man referred for Battlefield  Acupuncture was found to have a scalp lesion suspicious for malignancy as well as  several precancerous lesions. Results: Referral to a dermatologist led to  excision of a basal-cell cancer and treatment of actinic keratoses. Conclusions:  Practitioners of auricular acupuncture should be familiar with common skin  cancers and precancerous lesions; these practitioners are in a unique situation  to detect these common skin lesions.
C1 Department of Medicine, Yale University School of Medicine, and VA Connecticut Healthcare System, West Haven, CT.
   Department of Medicine, Yale University School of Medicine, and VA Connecticut Healthcare System, West Haven, CT.
NR 0
TC 0
SN 1933-659
EI 1933-658
J9 Med Acupunct
PD FEB 8
PY 2018
VL 30
IS 1
BP 39
EP 40
DI 10.1089/acu.2017.1261
PG 1
UT PubMed:29410720
PM 29410720
DA 2018-02-08
ER

PT J
AU Shi, J
   Ren, X
   Tian, Q
   Sun, A
   Chen, R
AF Shi, Jinghua
   Ren, Xinyu
   Tian, Qinjie
   Sun, Aijun
   Chen, Rong
TI Persistent megalocystic ovaries after ovarian hyperstimulation syndrome in a
SO Journal of ovarian research
LA English
DT Journal Article
DE Ovarian hyperstimulation syndrome; Ovarian torsion; Persistent megalocystic ovaries; Polycystic ovarian syndrome
AB BACKGROUND: Ovary enlargement is common in controlled ovarian stimulation, which  could continue several months during a successful pregnancy. However, persistent  megalocystic ovaries 3 years after ovarian hyperstimulation syndrome (OHSS) were  rare. Here we will present you the case and treatment as well as discuss the  probable etiology. CASE PRESENTATION: A 34-year-old woman with polycystic ovarian  syndrome (PCOS) and a history of infertility presented to the Department of  Obstetrics and Gynecology at Peking Union Medical College Hospital with abdominal  pain and persistently enlarged ovaries 36 months after OHSS. Enlarged ovaries  were evaluated with ultrasonography and serum tests. Diagnostic laparoscopic  surgery with detorsion and drainage followed by GnRHa treatment was performed.  Symptoms and ovarian size evaluated by vaginal ultrasound were the main outcome  measures. The patient was discharged from the hospital 5 days after surgery  without any remarkable complications. Both ovaries recovered to almost normal  after a monthly injection of GnRHa for 3 months. CONCLUSIONS: Ovarian enlargement  may persist for a long time in patients with severe OHSS even after sex hormone  levels and ovarian functions return to normal. Long term follow-up is necessary  and ovarian torsion should be suspected when accompanied by abdominal pain.  Acupuncture plus GnRHa treatment may be an effective way for these cases.
C1 Department of Obstetrics and Gynecology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College, Chinese Academy of Medical Science,Beijing, 100730, People's Republic of China.
   Department of Pathology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People'sRepublic of China.
   Department of Obstetrics and Gynecology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College, Chinese Academy of Medical Science,Beijing, 100730, People's Republic of China.
   Department of Obstetrics and Gynecology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College, Chinese Academy of Medical Science,Beijing, 100730, People's Republic of China.
   Department of Obstetrics and Gynecology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College, Chinese Academy of Medical Science,Beijing, 100730, People's Republic of China. chenrongpumch@163.com.
NR 0
TC 0
SN 1757-221
EI 
J9 J Ovarian Res
PD SEP 12
PY 2018
VL 11
IS 1
BP 79
EP 79
DI 10.1186/s13048-018-0451-7
PG 0
WC Adult; Female; Humans; Ovarian Hyperstimulation Syndrome; blood; Polycystic Ovary Syndrome; complications
UT PubMed:30201001
PM 30201001
DA 2018-09-12
ER

PT J
AU Enblom, A
   Lagerstedt, K
AF Enblom, Anna
   Lagerstedt, Kristina
TI Understanding rationales for acupuncture treated individuals' beliefs in acupuncture effects, to be able to maximize therapeutic results: A qualitative analysis
SO COMPLEMENTARY THERAPIES IN MEDICINE
LA English
DT Article
DE Acupuncture therapy; Complementary and alternative medicine; Expectations; Nausea; Relaxation; Qualitative methods
ID alternative medicine; chronic pain; placebo; complementary; expectations; touch
AB Objective: To investigate how individuals expressed rationales for their beliefs regarding efficacy of acupuncture. Methods: Qualitative data from participants of two different randomized sham-controlled trials, of relaxing (non cancer volunteers of the general population) or antiemetic (patients with cancer undergoing radiotherapy) effects of acupuncture was analyzed. Participants (n = 441) received genuine (n = 120 and n = 100) or sham (n = 121 and n = 100) (telescopic blunt sham-needle) relaxing or antiemetic acupuncture. The participants (n = 428; 97% response rate) expressed their belief regarding the efficacy of acupuncture, and n = 264 delivered qualitative rationales for their belief, analyzed using qualitative content analysis. Results: Of the 428 participants, 35 (8%) believed entirely that the acupuncture was effective, 209 (49%) believed much, 136 (32%) believed moderately, 39 (9%) believed a little, and 9 (2%) did not believe that the acupuncture was effective. Five categories and seven subcategories represented the meaning units of the central message of the rationales for the treatment belief. Participants with positive beliefs (believed entirely/much, n = 244) presented rationales related to: "Experienced positive effects", "Knowledge regarding effect-mechanisms of acupuncture", and "General trustworthiness of acupuncture". Participants with more negative beliefs (believed a little or not, n = 48) presented rationales related to: "Lack of feasibility of the acupuncture", "Varying effects", and "The effect is individual, not available for everybody". Conclusion: In order to strengthen acupuncture treated patients' beliefs in the efficacy of acupuncture during clinical practice or research, acupuncture therapists may consider emphasizing these aspects in the therapeutic situation.
C1 [Enblom, Anna; Lagerstedt, Kristina] Linkoping Univ, Div Physiotherapy, Dept Med & Hlth Sci, Linkoping, Sweden.
   [Lagerstedt, Kristina] Avonova, Vaxjo, Sweden.
   [Lagerstedt, Kristina] Linkoping Univ, Dept Med & Hlth Sci, Div Physiotherapy, Linkoping, Sweden.
C3 Linkoping University; Linkoping University
RP Enblom, A (corresponding author), Linkoping Univ, Dept Med & Hlth Sci, S-58183 Linkoping, Sweden.
EM anna.enblom@liu.se
FU Swedish Cancer Society; Vardal Institute; Region of Ostergotland; University of Linkoping; Cancer Rehabilitation Foundation; Osher Centrum for Integrative Medicine, Karolinska Institute
CR Unknown -, 2016, EVID-BASED COMPL ALT, V0, P0, DOI DOI 10.1155/2016/1720239
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NR 46
TC 1
Z9 2
U1 0
U2 5
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0965-2299
EI 1873-6963
J9 COMPLEMENT THER MED
JI Complement. Ther. Med.
PD AUG 15
PY 2018
VL 39
IS 
BP 101
EP 108
DI 10.1016/j.ctim.2018.04.006
PG 8
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GP3TF
UT WOS:000440775400017
PM 30012380
DA 2026-01-16
ER

PT J
AU Kotlyar, A
AF Kotlyar, Arkady
TI I Ching Balance Acupuncture Treatment of Migraines, Insomnia, and Depression in a
SO Medical acupuncture
LA English
DT Journal Article
DE I Ching Balance Acupuncture (ICBA); depression; insomnia; integrative medicine; migraine; ovariectomy
AB Introduction: Surgical menopause is associated with symptoms that can affect a  woman's quality of life (QoL) significantly. These symptoms include migraines,  insomnia, and depression. Case: A 45-year-old Caucasian female presented at an  acupuncture clinic. Fourteen years prior, she had been diagnosed with ovarian  carcinoma, underwent ovariectomy, and was prescribed hormone replacement therapy.  Deteriorating QoL caused her to seek acupuncture for migraines, insomnia, and  depression. The outcomes sought for treatment of this case included intensity,  duration, and frequency of migraines, insomnia, and depression, as well as her  QoL. The outcome measures were estimated monthly throughout her treatment. Each  was rated on a numeric scale of 0-10 (0 = "the lowest possible" and 10 = "the  worst imaginable"). At baseline, the patient rated the intensity, duration, and  frequency of each complaint as 10. She was treated with 60-minute, I Ching  Balance Acupuncture (ICBA) sessions once per week for 7 months. Results: This  acupuncture treatment did not cause any adverse events, pain, or discomfort. Her  migraines, insomnia, and depression decreased to a great extent. In addition,  this patient reported considerable improvement in her QoL. The improvement in her  QoL was inversely related to the intensity, duration, and frequency of her  complaints throughout her acupuncture treatment. Conclusions: This patient  reported a considerable improvement in all the outcome measures. She completed  the treatment after experiencing great improvement in her QoL. Additional,  larger-scale studies are warranted to investigate the effects of ICBA.
C1 Outpatient Pain Clinic, Kaplan Medical Center, Rehovot, Israel.
NR 0
TC 0
SN 1933-659
EI 1933-658
J9 Med Acupunct
PD FEB 8
PY 2018
VL 30
IS 1
BP 41
EP 45
DI 10.1089/acu.2017.1249
PG 4
UT PubMed:29410721
PM 29410721
DA 2018-02-08
ER

PT J
AU Armstrong, K
   Lanni, T
   Anderson, MM
   Patricolo, GE
AF Armstrong, Karen
   Lanni, Thomas, Jr.
   Anderson, Maureen M.
   Patricolo, Gail Elliott
TI Integrative medicine and the oncology patient: options and benefits
SO SUPPORTIVE CARE IN CANCER
LA English
DT Article
DE Integrative medicine; Cancer; Oncology patients; Oncology massage; Acupuncture; Naturopathic oncology
ID radiation-induced xerostomia; breast-cancer survivors; guided imagery; yoga program; acupuncture; massage; complementary; interventions; prevention; management
AB Cancer is a major public health problem, and cancer patients and survivors face many physical and emotional challenges after the initial diagnosis, through treatment, and in the post-treatment period. Different integrative medicine (IM) modalities can be used to mitigate some of the physical issues that originate from the cancer itself or the treatment and to promote well-being and emotional health. Here, we discuss how an IM Department can function in a hospital system, particularly with regard to oncology patients, the modalities appropriate for oncology patients, how these modalities can benefit this patient population, and the role of IM in cancer survivorship. A dedicated IM Department that works with oncologists provides support and care for the whole person. These different modalities work together to reduce pain, anxiety, and chemotherapy-induced nausea and peripheral neuropathy, while promoting immune function and improving sleep, range of motion, and an overall sense of well-being. However, each modality has different contraindications for the oncology patient, and proper training is required for safe and effective care. We illustrate how IM can be a valuable component of the care of the oncology patient.
C1 [Armstrong, Karen; Anderson, Maureen M.; Patricolo, Gail Elliott] Beaumont Hlth, Integrat Med, 3577 W Thirteen Mile Rd, Royal Oak, MI 48073 USA.
   [Lanni, Thomas, Jr.] Beaumont Hlth, Beaumont Canc Inst, Oncol Med & Imaging, Royal Oak, MI 48073 USA.
C3 Beaumont Health; Beaumont Health
RP Patricolo, GE (corresponding author), Beaumont Hlth, Integrat Med, 3577 W Thirteen Mile Rd, Royal Oak, MI 48073 USA.
EM gail.elliottpatricolo@beaumont.org
CR Unknown -, 2017, COMPLEMENTARY ALTERN, V0, P0
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NR 45
TC 22
Z9 24
U1 1
U2 23
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 0941-4355
EI 1433-7339
J9 SUPPORT CARE CANCER
JI Support. Care Cancer
PD JUL 15
PY 2018
VL 26
IS 7
BP 2267
EP 2273
DI 10.1007/s00520-017-4007-y
PG 7
WC Oncology; Health Care Sciences & Services; Rehabilitation
SC Oncology; Health Care Sciences & Services; Rehabilitation
GA GH9AL
UT WOS:000433961300022
PM 29396594
DA 2026-01-16
ER

PT J
AU Qi, X
   Chen, L
   Zhang, X
   Han, M
   He, W
   Su, Y
   Wang, X
   Jing, X
   Zhu, B
AF Qi, Xuezhi
   Chen, Lizhen
   Zhang, Xiaoning
   Han, Mingjuan
   He, Wei
   Su, Yangshuai
   Wang, Xiaoyu
   Jing, Xianghong
   Zhu, Bing
TI [Distribution of algesia sensitized acupoints in the patients of intestinal
SO Zhongguo zhen jiu = Chinese acupuncture & moxibustion
LA chi
DT Journal Article
DE acupoint sensitization; intestinal cancer; pressure-pain threshold
AB OBJECTIVE: To judge whether algesia sensitization of some acupoints is existed  and whether the acupoint algesia sensitization area is expanded in the patients  of intestinal cancer. METHODS: Totally, 30 patients of intestinal cancer and 30  healthy subjects were included. The electronic Von Fray was used to determine the  pressure-pain thresholds at 13 acupoints relevant with gastrointestinal disorders  and the reference points at the sites 1 cun and 2 cun lateral to those points as  well as the sites at the corresponding nerve segments. Compared with the  pressure-pain thresholds at the reference points of the different segments, the  relative value was calculated. The changes were analyzed in the pressure-pain  thresholds at the relevant acupoints on the body surface in the patients of  intestinal cancer as compared with the relative pressure-pain thresholds in the  healthy volunteers. RESULTS: The pressure-pain thresholds at Zusanli (ST 36),  Shangjuxu (ST 37), Xiajuxu (ST 39), Quchi (LI 11) and Dachangshu (BL 25) in the  patients of intestinal cancer were all significantly reduced as compared with  those of the healthy subjects (P<0.05, P<0.01, P<0.001). At the non-acupoint  sites 1 cun and 2 cun lateral to those acupoints as well as at the sites of the  same segments, the pressure-pain thresholds were reduced significantly as  compared with the control group (P<0.05, P<0.01, P<0.001). Particularly, the  sensitization zone of Yinlingquan (SP 9) focused on the acupoint, the site 1 cun  lateral to it as well as the non-acupoint sites of the same segments (P<0.01,  P<0.001). CONCLUSION: The acupoint sensitization is displayed at Zusanli (ST 36),  Shangjuxu (ST 37), Xiajuxu (ST 39), Quchi (LI 11), Dachangshu (BL 25) and  Yinlingquan (SP 9) and the sensitization area is expended in the patients of  intestinal cancer.
C1 Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
   Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
NR 0
TC 0
SN 
EI 0255-293
J9 Zhongguo Zhen Jiu
PD JAN 23
PY 2018
VL 37
IS 9
BP 963
EP 6
DI 10.13703/j.0255-2930.2017.09.014
PG -957
WC Acupuncture Analgesia; methods; Acupuncture Points; Cancer Pain; physiopathology; Case-Control Studies; Humans; Intestinal Neoplasms; physiopathology; Meridians; Pain Threshold
UT PubMed:29354918
PM 29354918
DA 2018-01-23
ER

PT J
AU Hershman, DL
   Unger, JM
   Greenlee, H
   Capodice, JL
   Lew, DL
   Darke, AK
   Kengla, AT
   Melnik, MK
   Jorgensen, C
   Kreisle, WH
   Minasian, LM
   Fisch, MJ
   Henry, NL
   Crew, KD
AF Hershman, Dawn L.
   Unger, Joseph M.
   Greenlee, Heather
   Capodice, Jillian L.
   Lew, Danika L.
   Darke, Amy K.
   Kengla, Alice T.
   Melnik, Marianne K.
   Jorgensen, CarlaW.
   Kreisle, William H.
   Minasian, Lori M.
   Fisch, Michael J.
   Henry, N. Lynn
   Crew, Katherine D.
TI Effect of Acupuncture vs Sham Acupuncture or Waitlist Control on Joint Pain Related to Aromatase Inhibitors Among Women With Early-Stage Breast Cancer A Randomized Clinical Trial
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Article; Proceedings Paper
ID quality-of-life; musculoskeletal symptoms; immpact recommendations; hormonal-therapy; arthralgia; outcm; placebo; discontinuation; multicenter; validation
AB IMPORTANCE Musculoskeletal symptoms are the most common adverse effects of aromatase inhibitors and often result in therapy discontinuation. Small studies suggest that acupuncture may decrease aromatase inhibitor-related joint symptoms. OBJECTIVE To determine the effect of acupuncture in reducing aromatase inhibitor-related joint pain. DESIGN, SETTING, AND PATIENTS Randomized clinical trial conducted at 11 academic centers and clinical sites in the United States from March 2012 to February 2017 (final date of follow-up, September 5, 2017). Eligible patients were postmenopausal women with early-stage breast cancer who were taking an aromatase inhibitor and scored at least 3 on the Brief Pain Inventory Worst Pain (BPI-WP) item (score range, 0-10; higher scores indicate greater pain). INTERVENTIONS Patients were randomized 2: 1: 1 to the true acupuncture (n = 110), sham acupuncture (n = 59), or waitlist control (n = 57) group. True acupuncture and sham acupuncture protocols consisted of 12 acupuncture sessions over 6 weeks (2 sessions per week), followed by 1 session per week for 6 weeks. The waitlist control group did not receive any intervention. All participants were offered 10 acupuncture sessions to be used between weeks 24 and 52. MAIN OUTCOMES AND MEASURES The primary end point was the 6-week BPI-WP score. Mean 6-week BPI-WP scores were compared by study group using linear regression, adjusted for baseline pain and stratification factors (clinically meaningful difference specified as 2 points). RESULTS Among 226 randomized patients (mean [SD] age, 60.7 [8.6] years; 88% white; mean [SD] baseline BPI-WP score, 6.6 [1.5]), 206 (91.1%) completed the trial. From baseline to 6 weeks, the mean observed BPI-WP score decreased by 2.05 points (reduced pain) in the true acupuncture group, by 1.07 points in the sham acupuncture group, and by 0.99 points in the waitlist control group. The adjusted difference for true acupuncture vs sham acupuncture was 0.92 points (95% CI, 0.20-1.65; P = .01) and for true acupuncture vs waitlist control was 0.96 points (95% CI, 0.24-1.67; P = .01). Patients in the true acupuncture group experienced more grade 1 bruising compared with patients in the sham acupuncture group (47% vs 25%; P = .01). CONCLUSIONS AND RELEVANCE Among postmenopausal women with early-stage breast cancer and aromatase inhibitor-related arthralgias, true acupuncture compared with sham acupuncture or with waitlist control resulted in a statistically significant reduction in joint pain at 6 weeks, although the observed improvement was of uncertain clinical importance.
C1 [Hershman, Dawn L.] Columbia Univ, Med Ctr, New York, NY USA.
   [Unger, Joseph M.; Greenlee, Heather; Lew, Danika L.; Darke, Amy K.] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
   [Unger, Joseph M.; Lew, Danika L.; Darke, Amy K.] SWOG Stat & Data Management Ctr, Seattle, WA USA.
   [Capodice, Jillian L.] Mt Sinai Hosp, New York, NY 10029 USA.
   [Kengla, Alice T.] Kaiser Permanente Med Ctr, Walnut Creek, CA USA.
   [Melnik, Marianne K.] Spectrum Hlth Med Grp, Grand Rapids, MI USA.
   [Jorgensen, CarlaW.] NCORP Carolinas Greenville Hlth Syst, Greenville, SC USA.
   [Kreisle, William H.] St Lukes Mt States Tumor Inst PCRC NCORP, Boise, ID USA.
   [Minasian, Lori M.] NCI, Canc Prevent Div, Bethesda, MD 20892 USA.
   [Fisch, Michael J.] AIM Specialty Hlth, Chicago, IL USA.
   [Henry, N. Lynn] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA.
C3 Columbia University; Fred Hutchinson Cancer Center; Southwest Oncology Group; Icahn School of Medicine at Mount Sinai; Kaiser Permanente; Spectrum Health Medical Group; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); Utah System of Higher Education; University of Utah; Huntsman Cancer Institute
RP Hershman, DL (corresponding author), Columbia Univ, 161 Ft Washington Ave,10-1068, New York, NY 10032 USA.
EM dlh23@columbia.edu
FU National Institutes of Health (NIH) National Center for Complementary and Integrative Health; Office of Research on Women's Health [R01AT006376]; NIH/NCI/DCP (Division of Cancer Prevention) [UG1CA189974, U10CA37429]; National Cancer Institute [UG1CA189974] Funding Source: NIH RePORTER
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NR 38
TC 242
Z9 290
U1 7
U2 158
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD JUL 10
PY 2018
VL 320
IS 2
BP 167
EP 176
DI 10.1001/jama.2018.8907
PG 10
WC Medicine, General & Internal
SC General & Internal Medicine
GA GM4MM
UT WOS:000438094900017
PM 29998338
DA 2026-01-16
ER

PT J
AU Tarrasch, R
   Carmel-Neiderman, NN
   Ben-Ami, S
   Kaufman, B
   Pfeffer, R
   Ben-David, M
   Gamus, D
AF Tarrasch, Ricardo
   Carmel-Neiderman, Narin N.
   Ben-Ami, Sarah
   Kaufman, Bella
   Pfeffer, Raphi
   Ben-David, Merav
   Gamus, Dorit
TI The Effect of Reflexology on the Pain-Insomnia-Fatigue Disturbance Cluster of Breast Cancer Patients During Adjuvant Radiation Therapy
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Article
DE reflexology; radiation therapy; fatigue; breast cancer
ID quality-of-life; interventions; survivors; yoga; complementary; radiotherapy; acupuncture; impact
AB Objective: To evaluate the effects of reflexology treatment on quality of life, sleep disturbances, and fatigue in breast cancer patients during radiation therapy. Methods/Subjects: A total of 72 women with breast cancer (stages 1-3) scheduled for radiation therapy were recruited. Design: Women were allocated upon their preference either to the group receiving reflexology treatments once a week concurrently with radiotherapy and continued for 10 weeks or to the control group (usual care). Outcome measures: The Lee Fatigue Scale, General Sleep Disturbance Scale, and Multidimensional Quality of Life Scale Cancer were completed by each patient in both arms at the beginning of the radiation treatment, after 5 weeks, and after 10 weeks of reflexology treatment. Results: The final analysis included 58 women. The reflexology treated group demonstrated statistically significant lower levels of fatigue after 5 weeks of radiation therapy (p<0.001), compared to the control group. It was also detected that although the quality of life in the control group deteriorated after 5 and 10 weeks of radiation therapy (p<0.01 and p<0.05, respectively), it was preserved in the reflexology group, which also demonstrated a significant improvement in the quality of sleep after 10 weeks of radiation treatment (p<0.05). Similar patterns were obtained in the assessment of the pain levels experienced by the patients. Conclusions: The results of the present study indicate that reflexology may have a positive effect on fatigue, quality of sleep, pain, and quality of life in breast cancer patients during radiation therapy. Reflexology prevented the decline in quality of life and significantly ameliorated the fatigue and quality of sleep of these patients. An encouraging trend was also noted in amelioration of pain levels.
C1 [Tarrasch, Ricardo] Tel Aviv Univ, Jaime & Joan Constantiner Sch Educ, Tel Aviv, Israel.
   [Carmel-Neiderman, Narin N.; Gamus, Dorit] Sheba Med Ctr, Complementary & Integrat Med Serv, IL-52621 Ramat Gan, Israel.
   [Ben-Ami, Sarah; Kaufman, Bella] Sheba Med Ctr, Dept Oncol, Ramat Gan, Israel.
   [Pfeffer, Raphi; Ben-David, Merav] Sheba Med Ctr, Dept Radiat Oncol, Ramat Gan, Israel.
   [Ben-David, Merav] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel.
C3 Tel Aviv University; Chaim Sheba Medical Center; Tel Aviv University; Tel Aviv University; Chaim Sheba Medical Center; Chaim Sheba Medical Center; Tel Aviv University; Tel Aviv University; Sackler Faculty of Medicine
RP Gamus, D (corresponding author), Sheba Med Ctr, Complementary & Integrat Med Serv, IL-52621 Ramat Gan, Israel.
EM dorit.gamus@sheba.health.gov.il
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NR 35
TC 27
Z9 30
U1 1
U2 17
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD JAN 15
PY 2018
VL 24
IS 1
BP 62
EP 68
DI 10.1089/acm.2017.0023
PG 7
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA FT1ZP
UT WOS:000422937900010
PM 28440664
DA 2026-01-16
ER

PT J
AU Omura, Y
   Lu, D
   Duvvi, H
   Yopor, D
   Nihrane, A
   Corro, P
   Corro, C
   Shimotsuura, Y
   Ohki, M
AF Omura, Yoshiaki
   Lu, Dominic
   Duvvi, Harsha
   Yopor, Dario
   Nihrane, Abdallah
   Corro, Prudencio
   Corro, Carol
   Shimotsuura, Yashihiro
   Ohki, Motomu
TI "CLINICAL DIAMOND" SECTION of Acupuncture & Electro-Therapeutics Research, International Journal of Integrated Medicine - Clinically Very Useful & Important Information in Diagnosis &/or Treatment of Patients
SO ACUPUNCTURE & ELECTRO-THERAPEUTICS RESEARCH
LA English
DT Article
DE Non-Invasive Early Diagnostic Method; Lung Cancer; Colon Cancer; Integral alpha 5 beta 1; 8-OH-dG; DNA Mutations; Optimal Dose of Vitamin D3 & White Fleshed Dragon Fruit; Selective Drug Uptake Enhancement Method; Thymus Gland Representation Area; Thymosin alpha 1; Thymosin beta 4
ID cancer
AB Our study indicated that cancer can develop in very short time if there is a strong coexisting infection of HPV-16 and HHV-8 in the presence of strong repeated electromagnetic field. Recently the first author himself developed cancer by drinking eggnog, which happened to contain strongest infection of both these 2 viruses, in the presence of Electro-magnetic field. Sometimes these cancers can also appear as a small metastatic mass in the back of the finger or hand. These metastatic tumors that are appearing in the hand are often misdiagnosed as benign lipoma since they do not seem to create any pain or other symptoms. In this article we described 2 examples of such an unusual metastatic tumor appearing as if it is a benign lipoma. If left untreated, or biopsy or surgical removal of these metastatic tumors can be new sources of metastases or unrecognized existence of an advanced tumor of original organ without significant symptoms. These rapidly developed cancers are infectious & difficult to treat. Fortunately, we succeeded in discovering an essential parameter required to completely inhibit these cancers by implementing the combination of the following 3 different methods given sequentially 1) Simultaneous Intake of Optimal Doses of Vitamin D3 (with 10 unique beneficial effects) every 8 hours & white fleshed Dragon fruit (since we found it containing close to optimal dose of DHEA, Zinc. Magnesium, Lithium, and a small amount of Vitamin D3 etc.) every 24 hours; 2) Selective Drug Uptake Enhancement Method; 3) Manual Stimulation of the Thymus Gland Representation Area of the Back of Each Hand. When these 3 different methods are used consequently there is a possibility of safe effective treatment for hopelessly advanced cancer patients, if Thymosin alpha 1 & Thymosin beta 4 are both very significantly increased to 800ng or higher.
C1 [Omura, Yoshiaki] New York Med Coll, Dept Family & Community Med, Valhalla, NY 10595 USA.
   [Omura, Yoshiaki] Int Coll Acupuncture & Electrotherapeut ICAET, New York, NY USA.
   [Omura, Yoshiaki] Heart Dis Res Fdn, Med Res, New York, NY USA.
   [Lu, Dominic; Yopor, Dario] Univ Penn, Oral Med, Philadelphia, PA 19104 USA.
   [Lu, Dominic; Yopor, Dario] Amer Soc Adv Anesthesia Dent, Bound Brook, NJ USA.
   [Lu, Dominic; Yopor, Dario] ICAET, Integrat Dent, New York, NY USA.
   [Duvvi, Harsha] New York Med Coll, Dept Family & Prevent Med, Valhalla, NY 10595 USA.
   [Duvvi, Harsha; Nihrane, Abdallah; Corro, Prudencio; Corro, Carol; Shimotsuura, Yashihiro] ICAET, Integrat Med, New York, NY USA.
   [Nihrane, Abdallah] Mt Sinai Sch Med, Dept Med, New York, NY USA.
   [Nihrane, Abdallah] NAIAD, NIH, Bethesda, MD USA.
   [Corro, Prudencio; Corro, Carol] ICAET, Integrat Nursing, New York, NY USA.
   [Shimotsuura, Yashihiro] Japan Bi Digital O Ring Test Assoc, Tokyo, Japan.
   [Shimotsuura, Yashihiro; Ohki, Motomu] ORT Life Sci Res Inst, Kurume, Fukuoka, Japan.
C3 New York Medical College; University of Pennsylvania; New York Medical College; Icahn School of Medicine at Mount Sinai; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID)
RP Omura, Y (corresponding author), 800 Riverside Dr,8-I, New York, NY 10032 USA.
EM icaet@vahoo.com
CR OMURA Y, 1994, ACUPUNCTURE ELECTRO, V19, P39, DOI 10.3727/036012994816357394
   Omura Y, 1995, ACUPUNCTURE ELECTRO, V20, P195, DOI 10.3727/036012995816357014
   Omura Y, 2000, ACUPUNCTURE ELECTRO, V25, P211
   Omura Y, 2008, ACUPUNCTURE ELECTRO, V33, P233
   Omura Y, 1900, PATENT NO. 5188107 5188107, V0, P0
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NR 13
TC 0
Z9 0
U1 2
U2 5
PU COGNIZANT COMMUNICATION CORP
PI PUTNAM VALLEY
PA 18 PEEKSKILL HOLLOW RD, PO BOX 37, PUTNAM VALLEY, NY 10579 USA
SN 0360-1293
EI 2167-9010
J9 ACUPUNCTURE ELECTRO
JI Acupunct. Electro-Ther. Res.
PD JUN 15
PY 2018
VL 43
IS 4
BP 359
EP 369
DI 10.3727/036012919X15475948072809
PG 11
WC Integrative & Complementary Medicine; Neurosciences
SC Integrative & Complementary Medicine; Neurosciences & Neurology
GA HL5RJ
UT WOS:000458787100004
DA 2026-01-16
ER

PT J
AU Lin, YP
   Li, YJ
   Chen, BL
   Guo, YH
AF Lin, Yong-Peng
   Li, Yong-Jin
   Chen, Bo-Lai
   Guo, Yu-Hai
TI Lumbar laminotomy and replantation for the treatment of adult spinal epidermoid
SO Medicine
LA English
DT Journal Article
AB RATIONALE: Adult spinal epidermoid cyst (SEC) is a rare tumor. Lumbar laminectomy  and tumor removal was a routine surgical procedure for adult spinal epidermoid  cyst according to the literature, but postoperative lumbar instability and  intractable low back pain may occur. In this study, we presented a brief report  of an adult lumbar epidermoid cyst and introduced another surgical approach.  PATIENT CONCERNS: This 28-year-old woman has been complaining of the severe right  buttock pain and right thigh radiating pain for half a year. She had been  diagnosed as sacroiliitis, spinal arthritis, and lumbar disc herniation at 3  different hospitals before coming to our hospital. And she received a variety of  conservative treatments, including non-steroidal anti-inflammatory drugs,  aspirin, acetaminophen, glucocorticoids, acupuncture, physical therapy, and so  on. However, her pain did not diminish at all. Finally, we find a space-occupying  lesion in her lumbar magnetic resonance images (MRI). The lesion was slightly  low, equal, and uneven equal-low signals on T1WI. T2WI showed slightly higher,  equal, and uneven equal-high signals. And a thin-rim enhancement was observed on  Gd-DTPA-enhanced MRI. DIAGNOSES: Adult spinal epidermoid cyst. INTERVENTIONS: The  patient underwent a surgery of lumbar laminectomy, tumor excision, and spinous  process-vertebral plate in situ replantation. OUTCOMES: Postoperative pathology  prompted that the tumor was cystoid. The patient's symptoms were completely  removed 1 week after surgery. Three-month postoperative MRI confirmed that the  spinal epidermoid cyst had been completely removed and three-dimensional CT  prompted lumbar lamina in situ. Bony fusion occurred at 6 months after the  surgery. LESSONS: Lumbar laminotomy and replantation provides an ideal option to  treat adult spinal epidermoid cyst because it can completely remove the cyst and  simultaneously reduce the risk of iatrogenic lumbar instability.
C1 Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
NR 0
TC 0
SN 1536-596
EI 0025-797
J9 Medicine (Baltimore)
PD MAR 6
PY 2018
VL 97
IS 1
BP e9334
EP e9334
DI 10.1097/MD.0000000000009334
PG 1
WC Adult; Epidermal Cyst; diagnostic imaging; Female; Humans; Laminectomy; methods; Lumbar Vertebrae; diagnostic imaging; Replantation; Spinal Diseases; diagnostic imaging
UT PubMed:29505514
PM 29505514
DA 2018-03-06
ER

PT J
AU Oh, PJ
   Kim, YL
AF Oh, Pok-Ja
   Kim, You Lim
TI Effectiveness of Non-Pharmacologic Interventions in Chemotherapy Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
SO JOURNAL OF KOREAN ACADEMY OF NURSING
LA Korean
DT Review
DE Chemotherapy; Adjuvant; Meta-analysis; Peripheral Nervous System Diseases
ID colorectal-cancer survivors; quality-of-life; acupuncture; management; strength; balance; oxaliplatin; therapy; trial
AB Purpose: This study was conducted to evaluate the effectiveness of non-pharmacologic interventions in chemotherapy-induced peripheral neuropathy (CIPN). Methods: PubMed, Cochrane Library CENTRAL, EMBASE, CINAHL, and several Korean databases (Until August 2017) were searched. The main search strategy combined terms for peripheral neuropathy and presence of neoplasms. The risk of bias was assessed using the Cochrane's Risk of Bias tool for randomized studies and the Risk of Bias Assessment tool for non-randomized studies. To estimate the effect size, a meta-analysis of the studies was performed using the Rev Man 5.3 program of the Cochrane Library random-effects models were used in the analyses. Results: Twenty-two studies with a total of 954 participants met the inclusion criteria. Of the 22 studies, 12 were used to estimate the effect size of the non-pharmacologic interventions. The non-pharmacologic interventions used in patients with CIPN were exercise, acupuncture, massage, and foot bath. The acupuncture significantly reduced CIPN symptoms and signs (d=-0.71) and CIPN pain (d=0.73) (p<.001). Massage and foot bath were also effective in reducing CIPN symptoms (d=-0.68; 950/0 Cl=-1.05,-0.30; p<.001; l(2)=19%).Exercises were effective in improving muscle strength and endurance(d=-0.55) and quality of life (d=-2.96), but they were not significantly effective in improving CIPN. Conclusion: Although these results provide little evidence of the effectiveness of acupuncture, massage, and foot bath in the treatment of CIPN, they suggest that these interventions can reduce CIPN symptoms in patients with cancer. However, the findings of this study should be interpreted with caution as there is a relative lack of data in this field, and additional well-designed studies are needed.
C1 [Oh, Pok-Ja] Sahmyook Univ, Dept Nursing, Seoul, South Korea.
   [Kim, You Lim] Sahmyook Univ, Dept Phys Therapy, Lab Rehabil & Hlth Sci, 815 Hwarang Ro, Seoul 01795, South Korea.
C3 Sahmyook University; Sahmyook University
RP Kim, YL (corresponding author), Sahmyook Univ, Dept Phys Therapy, Lab Rehabil & Hlth Sci, 815 Hwarang Ro, Seoul 01795, South Korea.
EM youlimy81@naver.com
FU National Research Foundation of Korea (NRF) - Korea government (MSIT) [NRF-2017RIA2B1002950]
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NR 45
TC 24
Z9 34
U1 2
U2 30
PU KOREAN SOC NURSING SCIENCE
PI SEOUL
PA KOREA SCIENCE & TECHNOL CTR, 635-4 YEOKSAM-DONG, KANGNAM-GU,, SEOUL, 135-703, SOUTH KOREA
SN 2005-3673
EI 2093-758X
J9 J KOREAN ACAD NURS
JI J. Korean Acad. Nurs.
PD APR 15
PY 2018
VL 48
IS 2
BP 123
EP 142
DI 10.4040/jkan.2018.48.2.123
PG 20
WC Nursing
SC Nursing
GA GG1CF
UT WOS:000432416200001
PM 29735874
DA 2026-01-16
ER

PT J
AU Yang, XJ
   Gong, J
   Jin, LM
   Liu, L
   Sun, JB
   Qin, W
AF Yang, Xuejuan
   Gong, Jie
   Jin, Lingmin
   Liu, Lin
   Sun, Jinbo
   Qin, Wei
TI Effect of catechol-O-methyltransferase Val158Met polymorphism on resting-state brain default mode network after acupuncture stimulation
SO BRAIN IMAGING AND BEHAVIOR
LA English
DT Article
DE Acupuncture; COMT Val158Met polymorphism; Default mode network; Connectivity; Resting-state
ID functional connectivity; electroacupuncture analgesia; val(158)met genotype; comt val(158)met; clinical-efficacy; cancer pain; modulation; responses; gene; morphine
AB The effects of acupuncture can be characterized by clear individual differences. Several revealing studies suggest an underlying role of inherited genetic factor in interindividual variability in response to acupuncture treatment. It remains unclear, however, if the modulation of acupuncture on resting brain function is influenced by genetic factors. Catechol-o-methyltransferase (COMT) Val158Met polymorphism has been shown to regulate the resting brain network, especially in the default mode network (DMN), which is a target area that responds to acupuncture stimulation. Therefore, the present study investigated the effect of COMT Val158Met polymorphism on the modulation of acupuncture in DMN connectivity in healthy Chinese young adults. Using mixed-design ANOVA analysis, we found a significant interactive effect between acupuncture and the COMT gene. For subjects carrying the Val/Met genotype, acupuncture induced decreased DMN connectivity with the left middle frontal gyrus during the post-acupuncture stage compared with the pre-acupuncture stage, which was not observed in Val/Val homozygous subjects. These results demonstrated that during sustained periods after acupuncture stimulation, the brain network is likely under genetic control, and COMT might be a candidate gene that regulates the resting DMN response to acupuncture stimulation.
C1 [Yang, Xuejuan; Gong, Jie; Jin, Lingmin; Liu, Lin; Sun, Jinbo; Qin, Wei] Xidian Univ, Sch Life Sci & Technol, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China.
C3 Xidian University
RP Qin, W (corresponding author), Xidian Univ, Sch Life Sci & Technol, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China.
EM wqin@xidian.edu.cn
FU National Basic Research Program of China [2014CB543203, 2015CB856403]; National Natural Science Foundation of China [81471811, 61401346, 81271644]
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NR 58
TC 5
Z9 6
U1 1
U2 7
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 1931-7557
EI 1931-7565
J9 BRAIN IMAGING BEHAV
JI Brain Imaging Behav.
PD JUN 15
PY 2018
VL 12
IS 3
BP 798
EP 805
DI 10.1007/s11682-017-9735-6
PG 8
WC Neuroimaging
SC Neurosciences & Neurology
GA GI6PB
UT WOS:000434491400016
PM 28608189
DA 2026-01-16
ER

PT J
AU Tick, H
   Nielsen, A
   Pelletier, KR
   Bonakdar, R
   Simmons, S
   Glick, R
   Ratner, E
   Lemmon, RL
   Wayne, P
   Zador, V
AF Tick, Heather
   Nielsen, Arya
   Pelletier, Kenneth R
   Bonakdar, Robert
   Simmons, Samantha
   Glick, Ronald
   Ratner, Emily
   Lemmon, Russell L
   Wayne, Peter
   Zador, Veronica
TI Evidence-Based Nonpharmacologic Strategies for Comprehensive Pain Care: The
SO Explore (New York, N.Y.)
LA English
DT Journal Article
DE Acute Pain Management; Chronic Pain Management; Evidence-Based Practice in Health Care System; Integrative Medicine; Non Surgical Pain Management; Public Health
AB Medical pain management is in crisis; from the pervasiveness of pain to  inadequate pain treatment, from the escalation of prescription opioids to an  epidemic in addiction, diversion and overdose deaths. The rising costs of pain  care and managing adverse effects of that care have prompted action from state  and federal agencies including the DOD, VHA, NIH, FDA and CDC. There is pressure  for pain medicine to shift away from reliance on opioids, ineffective procedures  and surgeries toward comprehensive pain management that includes evidence-based  nonpharmacologic options. This White Paper details the historical context and  magnitude of the current pain problem including individual, social and economic  impacts as well as the challenges of pain management for patients and a  healthcare workforce engaging prevalent strategies not entirely based in current  evidence. Detailed here is the evidence-base for nonpharmacologic therapies  effective in postsurgical pain with opioid sparing, acute non-surgical pain,  cancer pain and chronic pain. Therapies reviewed include acupuncture therapy,  massage therapy, osteopathic and chiropractic manipulation, meditative movement  therapies Tai chi and yoga, mind body behavioral interventions, dietary  components and self-care/self-efficacy strategies. Transforming the system of  pain care to a responsive comprehensive model necessitates that options for  treatment and collaborative care must be evidence-based and include effective  nonpharmacologic strategies that have the advantage of reduced risks of adverse  events and addiction liability. The evidence demands a call to action to increase  awareness of effective nonpharmacologic treatments for pain, to train healthcare  practitioners and administrators in the evidence base of effective  nonpharmacologic practice, to advocate for policy initiatives that remedy system  and reimbursement barriers to evidence-informed comprehensive pain care, and to  promote ongoing research and dissemination of the role of effective  nonpharmacologic treatments in pain, focused on the short- and long-term  therapeutic and economic impact of comprehensive care practices.
C1 Departments of Family Medicine, Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA. 
   Department of Family Medicine & Community Health, Icahn School of Medicine at Mount Sinai, New York, NY. 
   Department of Medicine, University of California School of Medicine, San Francisco, CA.
   Department of Pain Management, Scripps Center for Integrative Medicine, La Jolla, CA.
   Oregon Collaborative for Integrative Medicine, Portland, OR.
   Departments of Psychiatry and Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine, Pittsburgh, PA.
   MedStar Health, Institute for Innovation, Integrative Medicine Initiatives, MedStar Montgomery Medical Center, Washington, DC.
   Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, Madison, WI.
   Osher Center for Integrative Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
   Beaumont Hospital Integrative Medicine, Oakland University William Beaumont School of Medicine, Rochester, MI.
EM Arya.Nielsen@mountsinai.org
NR 0
TC 0
SN 1878-754
EI 
J9 Explore (NY)
PD MAY 8
PY 2018
VL 14
IS 3
BP 177
EP 211
DI 10.1016/j.explore.2018.02.001
PG 34
WC Acupuncture Therapy; Acute Pain; therapy; Analgesics, Opioid; Cancer Pain; therapy; Chronic Pain; therapy; Diet; Humans; Mind-Body Therapies; Musculoskeletal Manipulations; Pain; etiology; Pain Management; methods; Pain, Postoperative; therapy; Physical Therapy Modalities; Treatment Outcome
UT PubMed:29735382
PM 29735382
DA 2018-05-08
ER

PT J
AU Kim, HW
   Yoo, JE
AF Kim, Hae-Won
   Yoo, Jeong-Eun
TI Inhibitory effect of traditional Korean medicine on the recurrent endometriosis after laparoscopic excision: a case report
SO INTEGRATIVE MEDICINE RESEARCH
LA English
DT Article
DE Boheotang; Dienogest; Endometriosis; Laparoscopic surgery; traditional Korean medicine
ID dienogest; multicenter; symptoms; acetate; trial; women; pain
AB Endometriosis is a common benign gynecologic tumor, and it can destroy a patient's life. Surgery and hormone therapy are established therapies for endometriosis. However, there are many cases of recurrent endometriosis after conventional therapies. This report presents a case of a patient who has repetitive recurrence of endometriosis after laparoscopic excision and hormone therapy. A 32-years-old female patient first had laparoscopic surgery to remove endometriosis in 2011. The disease recurred two more times after the first excision. Hormone therapy by dienogest and two more laparoscopic surgeries were done in 2012 and 2014. With acupuncture, moxibustion, fumigation therapy, and herbal medicine therapy, endometriosis didn't recur during treatment and observation period of 34 months. Menstrual pain numeric rating scales (NRS) decreased from 2 to none. Shortened menstrual cycle (24 days) after second surgery became longer (26.63 +/- 2.28 days) after traditional Korean medicine therapy. This case presents the therapeutic potential of TKM for inhibitory effect on the recurrent endometriosis after laparoscopic excision and hormone therapy. (C) 2018 Korea Institute of Oriental Medicine. Publishing services by Elsevier B.V.
C1 [Kim, Hae-Won; Yoo, Jeong-Eun] Dae Jeon Univ, Dept Korean Med Obstet & Gynecol, Coll Korean Med, Daejeon, South Korea.
RP Yoo, JE (corresponding author), Dae Jeon Univ, Dept Korean Med Obstet & Gynecol, Dunsan Korean Med Hosp, 75 Daeduk Daero 176 Beon Gil, Daejeon 35235, South Korea.
EM jeyoo@dju.ac.kr
CR Abbott JA, 2003, HUM REPROD, V18, P1922, DOI 10.1093/humrep/deg275
   Unknown -, 2008, FERTIL STERIL, V90, PS260, DOI 10.1016/j.fertnstert.2008.08.057
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   Dong-Il-Kim, 2002, THE JOURNAL OF ORIENTAL OBSTETRICS ＆ GYNECOLOGY 대한한방부인과학회지, V15, P126
   Farquhar CM, 2000, BMJ-BRIT MED J, V320, P1449, DOI 10.1136/bmj.320.7247.1449
   Garry R, 2004, CURR OPIN OBSTET GYN, V16, P299, DOI 10.1097/01.gco.0000136496.95075.79
   Harada T, 2009, FERTIL STERIL, V91, P675, DOI 10.1016/j.fertnstert.2007.12.080
   Holoch KJ, 2010, CLIN OBSTET GYNECOL, V53, P429, DOI 10.1097/GRF.0b013e3181db7d71
   정명주, 2015, THE JOURNAL OF ORIENTAL OBSTETRICS ＆ GYNECOLOGY, V0, P0
   Kang AR, 2010, J KOREAN MED ASSOC, V53, P424, DOI 10.5124/jkma.2010.53.5.424
   Kennedy S, 2005, HUM REPROD, V20, P2698, DOI 10.1093/humrep/dei135
   Lee EunBang Lee EunBang, 1999, KOREAN JOURNAL OF PHARMACOGNOSY, V30, P137
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NR 23
TC 4
Z9 5
U1 0
U2 8
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 2213-4220
EI 2213-4239
J9 INTEGR MED RES
JI Integr. Med. Res.
PD SEP 15
PY 2018
VL 7
IS 3
BP 296
EP 301
DI 10.1016/j.imr.2018.07.003
PG 6
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GV1GA
UT WOS:000445817600012
PM 30271719
DA 2026-01-16
ER

PT J
AU Zhao, L
   Li, X
   Shi, Z
AF Zhao, Li
   Li, Xueqing
   Shi, Zhimin
TI [Clinical observation on severe acute pancreatitis treated with
SO Zhongguo zhen jiu = Chinese acupuncture & moxibustion
LA chi
DT Journal Article
DE IL-6; Point BL 25 (Dachangshu); Point ST 37 (Shangjuxu); TNF-α; amylase; electroacupuncture; severe acute pancreatitis
AB OBJECTIVE: To observe the clinical therapeutic effects on severe acute  pancreatitis (SAP) treated with electroacupuncture (EA), sparse-dense wave and 2  Hz/15 Hz, at Dachangshu (BL 25) and Shangjuxu (ST 37) assisting ulinastetin and  explore the effective therapeutic method for SAP. METHODS: A total of 120  patients of SAP were randomized into an observation group and a control group, 60  cases in each one. In the control group, the routine western medicine was adopted  with the intravenous drip with ulinastatin. In the observation group, on the  basis of the treatment as the control group, EA was applied at Dachangshu (BL 25)  and Shangjuxu (ST 37). The treatment was given once every day, 20 min each time.  The treatment was 2 weeks in the two groups. The recovery time of defecation, the  recovery time of bowel sound, the remission time of abdominal pain and the  hospitalization time were recorded in the patients of the two groups. The changes  in the tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6) and amylase, as  well as the scores in the acute physiology and chronic health evaluation Ⅱ  (APACHE Ⅱ) were compared in the patients of the two groups before treatment, and  on the 3rd, 8th and 14th days of treatment. The therapeutic effects, the cases of  surgical transfer or the cases of the transfer of intensive care unit (ICU) were  compared between the two groups. RESULTS: The recovery time of defecation, the  recovery time of bowel sound and the remission time of abdominal pain, as well as  the hospitalization time in the observation group were shorter than those in the  control group (all P <0.05). The levels of TNF-α, IL-6 and amylase, as well as  the scores of APACHE Ⅱ on the 3rd, 8th and 14th days of treatment were all  reduced as compared with those before treatment in the two groups (all P <0.05).  The results in the observation group were lower than those in the control group  (all P <0.05). The total effective rate was 95.0% (57/60) in the observation  group, better than 81.7% (49/60) in the control group (P <0.05). There were 1  case of surgical transfer and 0 case in ICU transfer in the observation group, 3  cases of surgical transfer and 2 cases in ICU transfer in the control group,  indicating the significant differences between the two groups (both P <0.05). .  CONCLUSION: EA at Dachangshu (BL 25) and Shangjuxu (ST 37) displays the  satisfactory accessory therapeutic effects on SAP treated with ulinastatin.
C1 Department of Digestive Internal Medicine, Tangshan Worker Hospital, Tangshan 063000, Hebei Province, China.
   School of TCM, North China University of Science and Technology, Tangshan 063000, Hebei Province.
   Department of Spleen and Stomach Disorder, Tangshan Chinese Medicine Hospital.
NR 0
TC 0
SN 
EI 0255-293
J9 Zhongguo Zhen Jiu
PD FEB 24
PY 2018
VL 38
IS 2
BP 132
EP 6
DI 10.13703/j.0255-2930.2018.02.005
PG -126
WC Acupuncture Points; Amylases; blood; Combined Modality Therapy; Electroacupuncture; Glycoproteins; therapeutic use; Humans; Interleukin-6; blood; Pancreatitis; therapy; Tumor Necrosis Factor-alpha; blood
UT PubMed:29473354
PM 29473354
DA 2018-02-24
ER

PT J
AU Lopez, G
   Garcia, MK
   Liu, W
   Spano, M
   Underwood, S
   Dibaj, SS
   Li, Y
   Moguel, R
   Williams, J
   Bruera, E
   Cohen, L
AF Lopez, Gabriel
   Garcia, M Kay
   Liu, Wenli
   Spano, Michael
   Underwood, Susan
   Dibaj, Seyedeh S
   Li, Yisheng
   Moguel, Rocio
   Williams, Janet
   Bruera, Eduardo
   Cohen, Lorenzo
TI Outpatient acupuncture effects on patient self-reported symptoms in oncology
SO Journal of Cancer
LA English
DT Journal Article
DE Acupuncture; Complementary health approach; Edmonton Symptom Assessment System; Integrative Medicine; Integrative Oncology; Patient Reported Outcomes
AB Background: Increased access to complementary therapies such as acupuncture at  academic medical centers has created new opportunities for management of cancer  and cancer treatment related symptoms. Methods: Patients presenting for  acupuncture treatment during calendar year 2016 at an outpatient integrative  medicine clinic in a comprehensive cancer center were asked to complete a  modified Edmonton Symptom Assessment Scale (ESAS; 16 symptoms, score 0-10, 10  worst possible) before and after each visit. ESAS subscales analyzed included  global (GDS; score 0-90), physical (PHS, 0-60) and psychological distress (PSS,  0-20). ESAS symptom score change pre/post acupuncture treatment & from baseline  visit to first follow up were evaluated by paired t-test. Results: Of 375  participants [mean age 55.6, 68.3% female, 73.9% white, most common cancer  diagnosis of breast (32.8%) and thoracic/head & neck (25.9%)], 73.3% had at least  one follow up acupuncture treatment [mean 4.6 (SD 5.1) treatments]. Highest/worst  symptoms at baseline were poor sleep (3.92), fatigue (3.43), well-being (3.31),  and pain (3.29). Statistically significant reduction/improvement (pre/post) was  observed for all ESAS symptoms and subscales for the initial acupuncture  treatment (p <0.001). Hot flashes had the highest mean reduction (-1.93),  followed by fatigue (-1.72), numbness/tingling (-1.70), and nausea (-1.67).  Clinically significant reductions were also observed for ESAS subscales of GDS  (-12.2), PHS (-8.5), and PSS (-2.6). For symptom change from initial acupuncture  treatment to first follow up (pre/pre), statistically and clinically significant  improvement was observed for spiritual pain (-1.10; p<0.001) and ESAS subscale of  GDS (-6.09; p=0.048). Clinical response rates (reduction ≥1) on follow up were  highest for symptoms of spiritual pain (58.9%), dry mouth (57.8%) and nausea  (57.3%). Conclusions: Outpatient acupuncture was associated with immediate &  longitudinal significant improvement across a range of symptoms commonly  experienced by individuals during cancer care. Further research is needed to  better understand frequency of treatments needed in clinical practice to help  maintain benefit.
C1 Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Biostatistics, The University of Texas MD Anderson Cancer Center.
   Department of Biostatistics, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
   Department of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center.
NR 0
TC 0
SN 1837-966
EI 1837-966
J9 J Cancer
PD OCT 13
PY 2018
VL 9
IS 19
BP 3613
EP 3619
DI 10.7150/jca.26527
PG 6
UT PubMed:30310519
PM 30310519
DA 2018-10-13
ER

PT J
AU McPhail, P
   Sandhu, H
   Dale, J
   Stewart-Brown, S
AF McPhail, P
   Sandhu, H
   Dale, J
   Stewart-Brown, S
TI Acupuncture in hospice settings: A qualitative exploration of patients'
SO European journal of cancer care
LA English
DT Journal Article
DE acupuncture; grounded theory; hospice; qualitative; well-being
AB Whilst acupuncture has the potential to impact on many aspects of health and  well-being, including end-of-life care, there is little research regarding  patients' experiences of its effects within the context of palliative care in  hospice settings. The aim of this study was to address this gap, by exploring  patients' experiences of acupuncture within this setting. In-depth,  semi-structured interviews were conducted with a sample of eighteen patients who  had received acupuncture as part of hospice care. Transcription of data, with  thematic analysis, identified two overarching themes: (1) participant perceptions  of the effects of acupuncture including pain control, improved physical and  emotional health, spiritual well-being and awareness of health as a holistic  phenomenon; and (2) factors which participants believed enabled acupuncture to  have these effects including the quality of the practitioner relationship,  engagement of participants in the process of their treatment and prior  expectations that acupuncture could work. Acupuncture was found to be a highly  acceptable, accessible and popular treatment with positive holistic effects  reported across the domains of physical, mental and spiritual health and no  serious adverse effects. By enabling awareness of the holistic nature of health  and well-being, acupuncture was experienced as having the potential to contribute  to a better death, an emergent theory that needs testing in further studies. In  the meanwhile, the results of this study offer encouragement to hospices  currently providing or considering investing in acupuncture provision.
C1 Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
   Division of Health Sciences, Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
   Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
   Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
NR 0
TC 0
SN 1365-235
EI 
J9 Eur J Cancer Care (Engl)
PD JAN 13
PY 2018
VL 27
IS 2
BP e12802
EP e12802
DI 10.1111/ecc.12802
PG 1
WC Acupuncture Therapy; psychology; Adult; Female; Hospice Care; methods; Humans; Male; Mental Health; Middle Aged; Neoplasms; psychology; Pain Management; methods; Palliative Care; methods; Patient Satisfaction; Qualitative Research; Spirituality; Young Adult
UT PubMed:29323766
PM 29323766
DA 2018-01-13
ER

PT J
AU Stoerkel, E
   Bellanti, D
   Paat, C
   Peacock, K
   Aden, J
   Setlik, R
   Walter, J
   Inman, A
AF Stoerkel, Erika
   Bellanti, Dawn
   Paat, Charmagne
   Peacock, Kimberly
   Aden, James
   Setlik, Robert
   Walter, Joan
   Inman, Alice
TI Effectiveness of a Self-Care Toolkit for Surgical Breast Cancer Patients in a
SO Journal of alternative and complementary medicine (New York, N.Y.)
LA English
DT Journal Article
DE anxiety; breast cancer; mind–body skills; pain; self-care; surgery
AB OBJECTIVE: To assess whether a self-care toolkit (SCT) provided to breast cancer  patients undergoing surgery could mitigate distress and lessen symptoms  associated with surgery. DESIGN: One hundred women with breast cancer, planning  to undergo initial surgery, were randomly assigned to either one of two groups:  treatment as usual (TAU; n = 49) or TAU with the addition of an SCT (n = 51). The  SCT contained an MP3 player with audio-files of guided mind-body techniques  (breathing, progressive muscle relaxation, meditation, guided imagery, and  self-hypnosis) and acupressure antinausea wristbands. Anxiety, pain, nausea,  sleep, fatigue, global health, and quality of life (QOL) were assessed using  validated outcome measures. Two inflammatory blood markers (erythrocyte  sedimentation rate [ESR] and C-reactive protein [CRP]) were measured serially.  Data were collected at baseline (T1), immediately before surgery (T2), within  10 h postoperatively (T3), and ∼2 weeks postsurgery (T4). SETTINGS: Numerous  studies have shown that psychological distress associated with a cancer diagnosis  can affect pain perception and QOL. RESULTS: Between T1 and T4, there were  significant between-group differences in Patient-Reported Outcomes Measurement  Information System (PROMIS)-57 scores of Pain Interference, Fatigue, and  Satisfaction with Social Roles, favoring the SCT group compared with TAU  (p = 0.005, p = 0.023, and p = 0.021, respectively). There was a significant mean  change in Defense and Veterans Pain Rating Scale (DVPRS) scores from T2 to T3,  with the SCT group having significantly smaller increases in postoperative pain  (p = 0.008) and in postoperative ESR (p = 0.0197) compared with the TAU group.  Clinically significant reductions in anxiety occurred in the SCT group during the  main intervention period. CONCLUSION: These results suggest that using the SCT in  the perioperative period decreased pain perceptions, fatigue, and inflammatory  cytokine secretion.
C1 1 Thought Leadership and Innovation Foundation , McLean, VA.
   1 Thought Leadership and Innovation Foundation , McLean, VA.
   1 Thought Leadership and Innovation Foundation , McLean, VA.
   2 Department of Epidemiology & Biostatistics, University of Texas Health San Antonio , San Antonio, TX.
   3 Brooke Army Medical Center , Fort Sam Houston, TX.
   3 Brooke Army Medical Center , Fort Sam Houston, TX.
   4 Samueli Institute , Alexandria, VA.
   3 Brooke Army Medical Center , Fort Sam Houston, TX.
NR 0
TC 0
SN 1557-770
EI 1075-553
J9 J Altern Complement Med
PD SEP 25
PY 2018
VL 24
IS 9-10
BP 916
EP 925
DI 10.1089/acm.2018.0069
PG 9
WC Adult; Anxiety; therapy; Breast Neoplasms; surgery; Female; Hospitals, Military; Humans; Middle Aged; Military Personnel; Mind-Body Therapies; Pain Management; methods; Self Care; methods; Treatment Outcome
UT PubMed:30247967
PM 30247967
DA 2018-09-25
ER

PT J
AU Kim, TH
   Kang, JW
   Lee, TH
AF Kim, Tae-Hun
   Kang, Jung Won
   Lee, Tae Hee
TI Therapeutic options for aromatase inhibitor-associated arthralgia in breast cancer survivors: A systematic review of systematic reviews, evidence mapping, and network meta-analysis
SO MATURITAS
LA English
DT Review
DE Scoping study; Overview of systematic reviews; Network meta-analysis; Aromatase inhibitor-associated arthralgia; Acupuncture
ID induced musculoskeletal symptoms; acupuncture; trial; management; estrogen; electroacupuncture; women
AB Aromatase inhibitor-associated arthralgia (AIA) is a common problem in breast cancer survivors and is associated with noncompliance with aromatase inhibitor therapy. The aim of this research was to assess the current evidence for the various therapeutic options available for AIA. We searched the PubMed, EMBASE, Cochrane Database of Systematic Reviews, and Database of Abstracts of Reviews of Effects for systematic reviews of trials investigating treatments for AIA to June 2018. Eligible systematic reviews were subjected to evidence mapping and the randomized controlled trials included in the systematic reviews were hand-searched for a network meta analysis. Six systematic reviews were included in the evidence mapping. Acupuncture was the most common treatment modality studied (four randomized controlled trials), and pharmacological interventions, aerobic exercise, Nordic walking, omega-3 fatty acids, and vitamin D were assessed less frequently. In view of the limitations in the overall confidence level for each review, the evidence for acupuncture as an effective treatment for AIA was considered low. Second, data from 6 randomized controlled trials were included in the network meta-analysis. When compared with a waiting list control, acupuncture (mean difference [MD] -2.00, 95% confidence interval [CI] -3.16, -0.84), aerobic exercise (MD -0.80, 95% CI-1.33, -0.016), and omega-3 fatty acids (MD -2.10, 95% CI -3.23, -0.97) significantly improved pain severity scores. Network meta-analysis of adverse events was not possible because of poor reporting. Acupuncture is presently the most widely investigated intervention but is recommended for MA with low overall confidence based on the current evidence.
C1 [Kim, Tae-Hun] Kyung Hee Univ, Korean Med Hosp, Korean Med Clin Trial Ctr, 23 Kyungheedae Ro, Seoul 130872, South Korea.
   [Kang, Jung Won] Kyung Hee Univ, Coll Korean Med, Dept Acupuncture & Moxibust, 23 Kyungheedae Ro, Seoul 130872, South Korea.
   [Lee, Tae Hee] Gachon Univ, Coll Korean Med, Dept Formulae Pharmacol, Seong Nam, South Korea.
C3 Kyung Hee University; Kyung Hee University Hospital; Kyung Hee University; Gachon University
RP Kim, TH (corresponding author), Kyung Hee Univ, Korean Med Hosp, Korean Med Clin Trial Ctr, 23 Kyungheedae Ro, Seoul 130872, South Korea.
EM taehunkim@khu.ac.kr
FU Korea Institute of Oriental Medicine in Republic of Korea [K18122]
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NR 38
TC 23
Z9 29
U1 0
U2 24
PU ELSEVIER IRELAND LTD
PI CLARE
PA ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND
SN 0378-5122
EI 1873-4111
J9 MATURITAS
JI Maturitas
PD DEC 15
PY 2018
VL 118
IS 
BP 29
EP 37
DI 10.1016/j.maturitas.2018.09.005
PG 9
WC Geriatrics & Gerontology; Obstetrics & Gynecology
SC Geriatrics & Gerontology; Obstetrics & Gynecology
GA HC2TD
UT WOS:000451653900005
PM 30415752
DA 2026-01-16
ER

PT J
AU Bullen, A
   Awdishu, L
   Lester, W
   Moore, T
   Trzebinska, D
AF Bullen, Alexander
   Awdishu, Linda
   Lester, Wendy
   Moore, Teri
   Trzebinska, Danuta
TI Effect of Acupuncture or Massage on Health-Related Quality of Life of Hemodialysis Patients
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Article
DE acupuncture; massage; psychological; anxiety; renal dialysis
ID stage renal-disease; chronic kidney-disease; restless legs syndrome; united-states; dialysis patients; symptom management; cancer-patients; sleep quality; follow-up; pain
AB Objective: The purpose of this study was to evaluate the effect of acupuncture and massage on health-related quality of life (HR-QOL) among end stage renal disease (ESRD) patients. Design: Pre-post test design. Setting: A hemodialysis (HD) unit located in a university hospital. Intervention: Participants were given the option to choose between 20min sessions of massage or acupuncture therapy once a week for 8 weeks by licensed acupuncturists and massage therapists while undergoing their usual HD session in the University of California, San Diego Chronic HD unit. Outcome measures: Participants were asked to complete pre- and postintervention surveys, which consisted of the Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Short Form and a Generalized Anxiety Disorder 7-item Scale. Results: A total of 101 patients were included in this study. The average age was 57.6 (standard deviation: 14.5) dialysis vintage 7.5 years, 58% patients were male and the most common etiology of ESRD was diabetic nephropathy (45%). Patients had multiple comorbidities as can be expected for this population with the most common being hypertension (94%), diabetes mellitus (53%), and cardiovascular disease (53%). In this brief intervention study, we were able to find a trend toward improvement in overall HR-QOL as determined by the PROMIS score (p=0.08). PROMIS mental raw score improved with intervention, which was statistically significant (p=0.034). Conclusion: Use of complementary therapies such as massage and acupuncture during HD may contribute toward improvement of HR-QOL and thus should be considered when addressing overall health status of these patients.
C1 [Bullen, Alexander; Lester, Wendy; Moore, Teri; Trzebinska, Danuta] Univ Calif San Diego, Div Nephrol, San Diego, CA 92103 USA.
   [Awdishu, Linda] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, San Diego, CA 92103 USA.
C3 University of California System; University of California San Diego; University of California System; University of California San Diego
RP Trzebinska, D (corresponding author), Univ Calif San Diego, Sch Med, Div Nephrol, 200 West Arbor Dr 8781, San Diego, CA 92103 USA.
EM dtrzebinska@ucsd.edu
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NR 34
TC 13
Z9 15
U1 1
U2 34
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD NOV 15
PY 2018
VL 24
IS 11
BP 1069
EP 1075
DI 10.1089/acm.2018.0030
EA MAY 2018
PG 7
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA HA2KF
UT WOS:000434708700001
PM 29851511
DA 2026-01-16
ER

PT J
AU Lu, W
   Rosenthal, DS
AF Lu, Weidong
   Rosenthal, David S
TI Oncology Acupuncture for Chronic Pain in Cancer Survivors: A Reflection on the
SO Hematology/oncology clinics of North America
LA English
DT Review
DE ASCO practice guideline; Cancer survivors; Chronic pain; Oncology acupuncture
AB Chronic pain syndromes associated with cancer treatment are common but difficult  to manage. The American Society of Clinical Oncology recently published a  practice guideline to address the unmet needs of cancer survivors, Management of  Chronic Pain in Survivors of Adult Cancers, which stresses the importance of  implementing integrative therapies including acupuncture. This review focuses on  randomized clinical trials of acupuncture for chronic pain in cancer survivors,  including its use in chemotherapy-induced peripheral neuropathy, aromatase  inhibitor-associated arthralgia, and post neck dissection pain, and provides  future directions of oncology acupuncture research in cancer survivorship. The  features of oncology acupuncture are also discussed.
C1 Leonard P. Zakim Center for Integrative Therapies and Healthy Living, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215,USA. 
   Leonard P. Zakim Center for Integrative Therapies and Healthy Living, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215,USA.
EM weidong_lu@dfci.harvard.edu
NR 0
TC 0
SN 1558-197
EI 
J9 Hematol Oncol Clin North Am
PD MAY 8
PY 2018
VL 32
IS 3
BP 519
EP 533
DI 10.1016/j.hoc.2018.01.009
PG 14
WC Acupuncture Analgesia; methods; Cancer Survivors; Chronic Pain; etiology; Humans; Medical Oncology; Neoplasms; pathology; Practice Guidelines as Topic; Societies, Medical; United States
UT PubMed:29729786
PM 29729786
DA 2018-05-08
ER

PT J
AU Hou, S
   Huh, B
   Kim, HK
   Kim, KH
   Abdi, S
AF Hou, Saiyun
   Huh, Billy
   Kim, Hee Kee
   Kim, Kyung-Hoon
   Abdi, Salahadin
TI Treatment of Chemotherapy-Induced Peripheral Neuropathy: Systematic Review and
SO Pain physician
LA English
DT Journal Article
AB BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is a commonly  encountered disease entity following chemotherapy for cancer treatment. Although  only duloxetine is recommended by the American Society of Clinical Oncology  (ASCO) for the treatment of CIPN in 2014, the evidence of the clinical outcome  for new pharmaceutic therapies and non-pharmaceutic treatments has not been  clearly determined. OBJECTIVE: To provide a comprehensive review and  evidence-based recommendations on the treatment of CIPN. STUDY DESIGN: A  systematic review of each treatment regimen in patients with CIPN. METHODS: The  literature on the treatment of CIPN published from 1990 to 2017 was searched and  reviewed. The 2011 American Academy of Neurology Clinical Practice Guidelines  Process Manual was used to grade the evidence and risk of bias. We reviewed and  updated the recommendations of the ASCO in 2014, and evaluated new approaches for  treating CIPN. RESULTS: A total of 26 treatment options in 35 studies were  identified. Among these, 7 successful RCTs, 6 failed RCTs, 18 prospective  studies, and 4 retrospective studies were included. The included studies examined  not only pharmacologic therapy but also other modalities, including laser  therapy, scrambler therapy, magnetic field therapy and acupuncture, etc. Most of  the included studies had small sample sizes, and short follow-up periods. Primary  outcome measures were highly variable across the included studies. No studies  were prematurely closed owing to its adverse effects. LIMITATIONS: The  limitations of this systematic review included relatively poor homogeneous, with  variations in timing of treatment, primary outcomes, and chemotherapeutic agents  used. CONCLUSION: The evidence is considered of moderate benefit for duloxetine.  Photobiomodulation, known as low level laser therapy, is considered of moderate  benefit based on the evidence review. Evidence did not support the use of  lamotrigine and topical KA (4% ketamine and 2% amitriptyline). The evidence for  tricyclic antidepressants was inconclusive as amitriptyline showed no benefit but  nortriptyline had insufficient evidence. Further research on CIPN treatment is  needed with larger sample sizes, long-term follow-up, standardized outcome  measurements, and standardized treatment timing. KEY WORDS: Chemotherapy-induced  neuropathy, peripheral neuropathy, chemotherapy-tumor, neuropathic pain, chronic  pain, toxicology, treatment, reduction of pain, level of evidence.
C1 Department of Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Department of Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Department of Pain Medicine, Division of Anesthesia and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Department of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Yangsan, Republic of Korea.
   University of Texas, MD Anderson Cancer Center, Houston, TX.
NR 0
TC 0
SN 2150-114
EI 
J9 Pain Physician
PD DEC 5
PY 2018
VL 21
IS 6
BP 571
EP 592
DI 
PG 21
WC Adult; Antineoplastic Agents; adverse effects; Humans; Neuralgia; chemically induced; Pain Management; methods; Peripheral Nervous System Diseases; chemically induced; Prospective Studies; Retrospective Studies
UT PubMed:30508986
PM 30508986
DA 2018-12-05
ER

PT J
AU DeMoss, P
   Ramsey, LH
   Karlson, CW
AF DeMoss, Patrick
   Ramsey, Logan H
   Karlson, Cynthia Windham
TI Phantom Limb Pain in Pediatric Oncology.
SO Frontiers in neurology
LA English
DT Review
DE adolescent; amputation; cancer; children; pediatrics; phantom limb pain; therapy; treatment
AB Phantom limb pain (PLP) is a prevalent problem for children and adolescents  undergoing amputation due to cancer treatment. The symptoms are wide ranging from  sharp to tingling. PLP in children typically lasts for a few minutes but can be  almost constant and can be highly distressing. This focused review describes the  characteristics, epidemiology, mechanisms, and evidence-based treatment of PLP in  pediatric populations, focusing on pediatric cancer. In pediatric oncology, the  administration of chemotherapy is a risk factor that potentially sensitizes the  nervous system and predisposes pediatric cancer patients to develop PLP after  amputation. Gabapentin, tricyclic antidepressants, opiates, nerve blocks, and  epidural catheters have shown mixed success in adults and case reports document  potential utility in pediatric patients. Non-pharmacologic treatments, such as  mirror therapy, psychotherapy, and acupuncture have also been used in pediatric  PLP with success. Prospective controlled trials are necessary to advance care for  pediatric patients with PLP.
C1 Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS, United States.
   School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States.
   Division of Hematology/Oncology, Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS, United States.
NR 0
TC 0
SN 1664-229
EI 1664-229
J9 Front Neurol
PD APR 25
PY 2018
VL 9
IS 
BP 219
EP 219
DI 10.3389/fneur.2018.00219
PG 0
UT PubMed:29686645
PM 29686645
DA 2018-04-25
ER

PT J
AU Magno, S
   Filippone, A
   Scaldaferri, A
AF Magno, Stefano
   Filippone, Alessio
   Scaldaferri, Assunta
TI Evidence-based usefulness of integrative therapies in breast cancer
SO TRANSLATIONAL CANCER RESEARCH
LA English
DT Review
DE Integrative oncology; precision medicine; lifestyle; complementary therapies; breast cancer (BC)
ID quality-of-life; physical-activity; music-therapy; alternative medicine; postoperative pain; radical-mastectomy; double-blind; hot flashes; olive oil; acupuncture
AB In a modern concept of Precision Medicine, clinical approach should be tailored to a single patient with cancer rather than only to cancer itself, by combining a deep understanding of genetic and molecular features of her disease, the most updated and evidence-based treatments available and patient's values and needs. Integrative oncology is a global strategy that includes lifestyle interventions and complementary therapies into mainstream care, to reduce the huge impact of oncological treatments for breast cancer (BC) both on patients' physical and psycho-social aspects of life at any ages. This paper summarizes the major clinical and scientific evidences about the impact of lifestyle changes and usefulness of complementary treatments currently used in breast cancer management.
C1 [Magno, Stefano; Filippone, Alessio; Scaldaferri, Assunta] Univ Cattolica Sacro Cuore, Fdn Policlin Univ Agostino Gemelli, Multidisciplinary Breast Ctr, Rome, Italy.
C3 Catholic University of the Sacred Heart; IRCCS Policlinico Gemelli
RP Magno, S (corresponding author), Univ Cattolica Sacro Cuore, Fdn Policlin Univ Agostino Gemelli, Multidisciplinary Breast Ctr, Rome, Italy.
EM stefano.magno@policlinicogemelli.it
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NR 79
TC 5
Z9 5
U1 3
U2 16
PU AME PUBLISHING COMPANY
PI SHATIN
PA FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG 00000, PEOPLES R CHINA
SN 2218-676X
EI 2219-6803
J9 TRANSL CANCER RES
JI Transl. Cancer Res.
PD APR 15
PY 2018
VL 7
IS 
BP S379
EP S389
DI 10.21037/tcr.2018.02.06
PG 11
WC Oncology
SC Oncology
GA GF3IM
UT WOS:000431841600013
DA 2026-01-16
ER

PT J
AU Tick, H
   Nielsen, A
   Pelletier, KR
   Bonakdar, R
   Simmons, S
   Glick, R
   Ratner, E
   Lemmon, RL
   Wayne, P
   Zador, V
AF Tick, Heather
   Nielsen, Arya
   Pelletier, Kenneth R.
   Bonakdar, Robert
   Simmons, Samantha
   Glick, Ronald
   Ratner, Emily
   Lemmon, Russell L.
   Wayne, Peter
   Zador, Veronica
TI EVIDENCE-BASED NONPHARMACOLOGIC STRATEGIES FOR COMPREHENSIVE PAIN CARE: THE CONSORTIUM PAIN TASK FORCE WHITE PAPER
SO EXPLORE-THE JOURNAL OF SCIENCE AND HEALING
LA English
DT Article
DE Non Surgical Pain Management; Public Health; Evidence-Based Practice in Health Care System; Acute Pain Management; Integrative Medicine; Chronic Pain Management
ID low-back-pain; cognitive-behavioral therapy; chronic musculoskeletal pain; randomized controlled-trial; arthroscopic partial meniscectomy; mindfulness-based interventions; polyunsaturated fatty-acids; alexander technique lessons; chronic neuropathic pain; mental-health disorders
AB Medical pain management is in crisis; from the pervasiveness of pain to inadequate pain treatment, from the escalation of prescription opioids to an epidemic in addiction, diversion and overdose deaths. The rising costs of pain care and managing adverse effects of that care have prompted action from state and federal agencies including the DOD, VHA, NIH, FDA and CDC. There is pressure for pain medicine to shift away from reliance on opioids, ineffective procedures and surgeries toward comprehensive pain management that includes evidence-based nonpharmacologic options. This White Paper details the historical context and magnitude of the current pain problem including individual, social and economic impacts as well as the challenges of pain management for patients and a healthcare workforce engaging prevalent strategies not entirely based in current evidence. Detailed here is the evidence-base for nonpharmacologic therapies effective in postsurgical pain with opioid sparing, acute non-surgical pain, cancer pain and chronic pain. Therapies reviewed include acupuncture therapy, massage therapy, osteopathic and chiropractic manipulation, meditative movement therapies Tai chi and yoga, mind body behavioral interventions, dietary components and self-care/self-efficacy strategies. Transforming the system of pain care to a responsive comprehensive model necessitates that options for treatment and collaborative care must be evidence-based and include effective nonpharmacologic strategies that have the advantage of reduced risks of adverse events and addiction liability. The evidence demands a call to action to increase awareness of effective nonpharmacologic treatments for pain, to train healthcare practitioners and administrators in the evidence base of effective nonpharmacologic practice, to advocate for policy initiatives that remedy system and reimbursement barriers to evidence informed comprehensive pain care, and to promote ongoing research and dissemination of the role of effective nonpharmacologic treatments in pain, focused on the short- and long-term therapeutic and economic impact of comprehensive care practices.
C1 [Tick, Heather] Univ Washington, Sch Med, Dept Family Med, Seattle, WA 98195 USA.
   [Tick, Heather] Univ Washington, Sch Med, Dept Anesthesiol, Seattle, WA 98195 USA.
   [Tick, Heather] Univ Washington, Sch Med, Dept Pain Med, Seattle, WA 98195 USA.
   [Nielsen, Arya] Icahn Sch Med Mt Sinai, Dept Family Med & Community Hlth, New York, NY 10029 USA.
   [Pelletier, Kenneth R.] Univ Calif San Francisco, Sch Med, Dept Med, San Francisco, CA USA.
   [Bonakdar, Robert] Scripps Ctr Integrat Med, Dept Pain Management, La Jolla, CA USA.
   [Simmons, Samantha] Oregon Collaborat Integrat Med, Portland, OR USA.
   [Glick, Ronald] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA USA.
   [Glick, Ronald] Univ Pittsburgh, Sch Med, Dept Phys Med & Rehabil, Pittsburgh, PA USA.
   [Ratner, Emily] MedStar Montgomery Med Ctr, Integrat Med Initiat, Inst Innovat, MedStar Hlth, Washington, DC USA.
   [Lemmon, Russell L.] Univ Wisconsin, Dept Family Med & Community Hlth, Sch Med & Publ Hlth, Madison, WI USA.
   [Wayne, Peter] Brigham & Womens Hosp, Osher Ctr Integrat Med, 75 Francis St, Boston, MA 02115 USA.
   [Wayne, Peter] Harvard Med Sch, Boston, MA USA.
   [Zador, Veronica] Oakland Univ, Beaumont Hosp Integrat Med, William Beaumont Sch Med, Rochester, MI 48063 USA.
C3 University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; Icahn School of Medicine at Mount Sinai; University of California System; University of California San Francisco; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Wisconsin System; University of Wisconsin Madison; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Oakland University
RP Tick, H (corresponding author), Univ Washington, Sch Med, Dept Family Med, Seattle, WA 98195 USA.; Tick, H (corresponding author), Univ Washington, Sch Med, Dept Anesthesiol, Seattle, WA 98195 USA.; Tick, H (corresponding author), Univ Washington, Sch Med, Dept Pain Med, Seattle, WA 98195 USA.; Nielsen, A (corresponding author), Icahn Sch Med Mt Sinai, Dept Family Med & Community Hlth, New York, NY 10029 USA.
EM HTick@uw.edu; Arya.Nielsen@mountsinai.org
FU National Center for Complementary and Integrative Health [K24AT009282] Funding Source: NIH RePORTER; NCCIH NIH HHS [K24 AT009282] Funding Source: Medline
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NR 463
TC 227
Z9 284
U1 4
U2 54
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1550-8307
EI 1878-7541
J9 EXPLORE-NY
JI Explore-J Sci. Heal.
PD MAY-JUN 15
PY 2018
VL 14
IS 3
BP 177
EP 211
DI 10.1016/j.explore.2018.02.001
PG 35
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GM1GM
UT WOS:000437814100011
PM 29735382
DA 2026-01-16
ER

PT J
AU DeMoss, P
   Ramsey, LH
   Karlson, CW
AF DeMoss, Patrick
   Ramsey, Logan H.
   Karlson, Cynthia Windham
TI Phantom Limb Pain in Pediatric Oncology
SO FRONTIERS IN NEUROLOGY
LA English
DT Review
DE phantom limb pain; pediatrics; cancer; therapy; amputation; children; adolescent; treatment
ID mirror therapy; postamputation pain; adolescent amputees; amputation; gabapentin; child; amitriptyline; sensations; placebo
AB Phantom limb pain (PLP) is a prevalent problem for children and adolescents undergoing amputation due to cancer treatment. The symptoms are wide ranging from sharp to tingling. PLP in children typically lasts for a few minutes but can be almost constant and can be highly distressing. This focused review describes the characteristics, epidemiology, mechanisms, and evidence-based treatment of PLP in pediatric populations, focusing on pediatric cancer. In pediatric oncology, the administration of chemotherapy is a risk factor that potentially sensitizes the nervous system and predisposes pediatric cancer patients to develop PLP after amputation. Gabapentin, tricyclic antidepressants, opiates, nerve blocks, and epidural catheters have shown mixed success in adults and case reports document potential utility in pediatric patients. Non-pharmacologic treatments, such as mirror therapy, psychotherapy, and acupuncture have also been used in pediatric PLP with success. Prospective controlled trials are necessary to advance care for pediatric patients with PLP.
C1 [DeMoss, Patrick] Univ Mississippi, Med Ctr, Dept Pediat, Jackson, MS 39216 USA.
   [Ramsey, Logan H.] Univ Mississippi, Med Ctr, Sch Med, Jackson, MS 39216 USA.
   [Karlson, Cynthia Windham] Univ Mississippi, Med Ctr, Dept Pediat, Div Hematol Oncol, Jackson, MS 39216 USA.
C3 University of Mississippi Medical Center; University of Mississippi; University of Mississippi; University of Mississippi Medical Center; University of Mississippi Medical Center; University of Mississippi
RP DeMoss, P (corresponding author), Univ Mississippi, Med Ctr, Dept Pediat, Jackson, MS 39216 USA.
EM pdemoss@umc.edu
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NR 37
TC 22
Z9 25
U1 0
U2 18
PU FRONTIERS MEDIA SA
PI LAUSANNE
PA AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
SN 1664-2295
EI 
J9 FRONT NEUROL
JI Front. Neurol.
PD APR 9
PY 2018
VL 9
IS 
BP 
EP 
DI 10.3389/fneur.2018.00219
PG 4
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA GC0NU
UT WOS:000429475000001
PM 29686645
DA 2026-01-16
ER

PT J
AU Lopez, G
   Garcia, MK
   Liu, WL
   Spano, M
   Underwood, S
   Dibaj, SS
   Li, YS
   Moguel, R
   Williams, J
   Bruera, E
   Cohen, L
AF Lopez, Gabriel
   Garcia, M. Kay
   Liu, Wenli
   Spano, Michael
   Underwood, Susan
   Dibaj, Seyedeh S.
   Li, Yisheng
   Moguel, Rocio
   Williams, Janet
   Bruera, Eduardo
   Cohen, Lorenzo
TI Outpatient acupuncture effects on patient self-reported symptoms in oncology care: a retrospective analysis
SO JOURNAL OF CANCER
LA English
DT Article
DE Integrative Medicine; Integrative Oncology; Acupuncture; Complementary health approach; Patient Reported Outcomes; Edmonton Symptom Assessment System
ID cancer-patients; pain
AB Background: Increased access to complementary therapies such as acupuncture at academic medical centers has created new opportunities for management of cancer and cancer treatment related symptoms. Methods: Patients presenting for acupuncture treatment during calendar year 2016 at an outpatient integrative medicine clinic in a comprehensive cancer center were asked to complete a modified Edmonton Symptom Assessment Scale (ESAS; 16 symptoms, score 0-10, 10 worst possible) before and after each visit. ESAS subscales analyzed included global (GDS; score 0-90), physical (PHS, 0-60) and psychological distress (PSS, 0-20). ESAS symptom score change pre/post acupuncture treatment & from baseline visit to first follow up were evaluated by paired t-test. Results: Of 375 participants [mean age 55.6, 68.3% female, 73.9% white, most common cancer diagnosis of breast (32.8%) and thoracic/head & neck (25.9%)], 73.3% had at least one follow up acupuncture treatment [mean 4.6 (SD 5.1) treatments]. Highest/worst symptoms at baseline were poor sleep (3.92), fatigue (3.43), well-being (3.31), and pain (3.29). Statistically significant reduction/improvement (pre/post) was observed for all ESAS symptoms and subscales for the initial acupuncture treatment (p <0.001). Hot flashes had the highest mean reduction (-1.93), followed by fatigue (-1.72), numbness/tingling (-1.70), and nausea (-1.67). Clinically significant reductions were also observed for ESAS subscales of GDS (-12.2), PHS (-8.5), and PSS (-2.6). For symptom change from initial acupuncture treatment to first follow up (pre/pre), statistically and clinically significant improvement was observed for spiritual pain (-1.10; p<0.001) and ESAS subscale of GDS (-6.09; p=0.048). Clinical response rates (reduction >= 1) on follow up were highest for symptoms of spiritual pain (58.9%), dry mouth (57.8%) and nausea (57.3%). Conclusions: Outpatient acupuncture was associated with immediate & longitudinal significant improvement across a range of symptoms commonly experienced by individuals during cancer care. Further research is needed to better understand frequency of treatments needed in clinical practice to help maintain benefit.
C1 [Lopez, Gabriel; Garcia, M. Kay; Liu, Wenli; Spano, Michael; Underwood, Susan; Moguel, Rocio; Williams, Janet; Bruera, Eduardo; Cohen, Lorenzo] Univ Texas MD Anderson Canc Ctr, Dept Palliat Rehabil & Integrat Med, Houston, TX 77030 USA.
   [Dibaj, Seyedeh S.; Li, Yisheng] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center
RP Lopez, G (corresponding author), Univ Texas MD Anderson Canc Ctr, Dept Palliat Rehabil & Integrat Med, Houston, TX 77030 USA.
EM gabriel.lopez@mdanderson.org
FU Duncan Family Institute for Cancer Prevention and Risk Assessment
CR Bruera E, 1991, J PALLIAT CARE, V7, P6
   Delgado-Guay MO, 2016, PALLIAT SUPPORT CARE, V14, P341, DOI 10.1017/S147895151500108X
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NR 14
TC 21
Z9 25
U1 0
U2 5
PU IVYSPRING INT PUBL
PI LAKE HAVEN
PA PO BOX 4546, LAKE HAVEN, NSW 2263, AUSTRALIA
SN 1837-9664
EI 
J9 J CANCER
JI J. Cancer
PD JUN 15
PY 2018
VL 9
IS 19
BP 3613
EP 3619
DI 10.7150/jca.26527
PG 7
WC Oncology
SC Oncology
GA GS9EM
UT WOS:000444018800021
PM 30310519
DA 2026-01-16
ER

PT J
AU Bao, T
   Seidman, AD
   Piulson, L
   Vertosick, E
   Chen, X
   Vickers, AJ
   Blinder, VS
   Zhi, WI
   Li, Q
   Vahdat, LT
   Dickler, MN
   Robson, ME
   Mao, JJ
AF Bao, Ting
   Seidman, Andrew D
   Piulson, Lauren
   Vertosick, Emily
   Chen, Xi
   Vickers, Andrew J
   Blinder, Victoria S
   Zhi, Wanqing I
   Li, Qing
   Vahdat, Linda T
   Dickler, Maura N
   Robson, Mark E
   Mao, Jun J
TI A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral
SO European journal of cancer (Oxford, England : 1990)
LA English
DT Journal Article
DE Acupuncture; Breast cancer; CIPN; Chemotherapy; Chemotherapy-induced peripheral neuropathy; Paclitaxel
AB PURPOSE: Chemotherapy-induced peripheral neuropathy (CIPN) is a common and  potentially dose-limiting side-effect of neurotoxic chemotherapy for cancer  patients. We evaluated the preliminary efficacy of acupuncture in preventing  worsening CIPN in patients receiving paclitaxel. METHODS: In this phase IIA  single-arm clinical trial, we screened stage I-III breast cancer patients  receiving neoadjuvant/adjuvant weekly paclitaxel for development of CIPN. The  primary objective was to assess acupuncture's efficacy in preventing the  escalation of National Cancer Institute-Common Toxicity Criteria for Adverse  Events (NCI-CTCAE), version 4.0, grade II CIPN to higher grades. Acupuncture was  deemed worthy of further study if 23 or more of the 27 enrolled patients did not  develop grade III CIPN. Outcome measures (NCI-CTCAE CIPN grade, Functional  Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity  [FACT/GOG-Ntx], Neuropathic Pain Scale [NPS]) were obtained weekly during the  intervention. RESULTS: Of 104 patients screened, 37 developed grade II CIPN  (36%), and 28 (27%) enrolled into the intervention phase; one was removed due to  protocol violation. Of the 27 patients receiving acupuncture, 26 completed  paclitaxel treatment without developing grade III CIPN, meeting our prespecified  success criteria for declaring acupuncture worthy of further study. FACT/GOG-Ntx  and NPS scores remained stable during the intervention while continuing weekly  paclitaxel. Acupuncture treatment was well tolerated; 4 of 27 (15%) patients  reported grade I bruising. CONCLUSIONS: Acupuncture was safe and showed  preliminary evidence of effectiveness in reducing the incidence of high grade  CIPN during chemotherapy. A follow-up randomised controlled trial is needed to  establish definitive efficacy in CIPN prevention for patients at risk.
C1 Memorial Sloan Kettering Cancer Center, 1429 First Avenue, New York, NY, 10021, USA. 
   Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA. 
   Memorial Sloan Kettering Cancer Center, 1429 First Avenue, New York, NY, 10021, USA. 
   Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, New York, NY, 10017, USA. 
   Memorial Sloan Kettering Cancer Center, 444 E 68th Street, New York, NY, 10065, USA. 
   Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, New York, NY, 10017, USA. 
   Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, New York, NY, 10017, USA. 
   Memorial Sloan Kettering Cancer Center Commack, 650 Commack Road, Commack, NY, 11725, USA. 
   Memorial Sloan Kettering Cancer Center, 1429 First Avenue, New York, NY, 10021, USA. 
   Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA. 
   Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA. 
   Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA. 
   Memorial Sloan Kettering Cancer Center, 1429 First Avenue, New York, NY, 10021, USA.
EM maoj@mskcc.org
NR 0
TC 0
SN 1879-085
EI 0959-804
J9 Eur J Cancer
PD JUL 17
PY 2018
VL 101
IS 
BP 12
EP 19
DI 10.1016/j.ejca.2018.06.008
PG 7
WC Acupuncture Therapy; adverse effects; Adult; Antineoplastic Combined Chemotherapy Protocols; adverse effects; Breast Neoplasms; drug therapy; Chemotherapy, Adjuvant; Contusions; etiology; Female; Humans; Middle Aged; Neoadjuvant Therapy; Paclitaxel; administration & dosage; Peripheral Nervous System Diseases; chemically induced; Severity of Illness Index; Treatment Outcome
UT PubMed:30007894
PM 30007894
DA 2018-07-17
ER

PT J
AU Genovese, TJ
   Mao, JJ
AF Genovese, Timothy J
   Mao, Jun J
TI Genetic Predictors of Response to Acupuncture for Aromatase Inhibitor-Associated
SO Pain medicine (Malden, Mass.)
LA English
DT Journal Article
AB OBJECTIVE: To evaluate the associations between polymorphisms in two genes,  catechol-O-methyltransferase and T-cell leukemia/lymphoma 1 A, and  acupuncture-mediated pain reduction among breast cancer survivors with aromatase  inhibitor-associated arthralgia. DESIGN, SETTING, AND SUBJECTS: Biospecimens were  obtained from 38 patients enrolled in a clinical trial of acupuncture for  aromatase inhibitor-associated arthralgia in postmenopausal hormone  receptor-positive breast cancer survivors. METHODS: We used polymerase chain  reaction to genotype the rs4680 (Val158Met) and rs4633 (His62His) variants in the  catechol-O-methyltransferase gene and rs2369049 (A > G) and rs7158782 (A > G)  variants in the T-cell leukemia/lymphoma 1 A gene. Response to acupuncture was  defined by 30% reduction in end-of-treatment average pain, measured by the Brief  Pain Inventory. We used Fisher exact tests to evaluate associations between  genotype and treatment response. RESULTS: Among participants, all six (15.8%)  subjects who expressed AA in locus rs4680 responded to acupuncture. In a combined  analysis, the 18 (47.4%) subjects with the responder genotype at either rs4680  (AA) or rs2369049 (GG or AG) were significantly more likely to respond to  acupuncture than those without (77.8% vs 45.0%, P = 0.039). CONCLUSIONS: Specific  genetic variations at loci rs4680 and rs2369049 are associated with response to  acupuncture-type intervention for management of arthralgia. These results serve  as a proof of concept for applying a precision medicine framework to the study of  cancer pain management.
C1 The Warren Alpert Medical School, Brown University, Providence, Rhode Island.
   Department of Integrative Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
NR 0
TC 0
SN 1526-463
EI 1526-237
J9 Pain Med
PD JUN 19
PY 2018
VL 20
IS 1
BP 191
EP 194
DI 10.1093/pm/pny067
PG 3
WC Acupuncture Therapy; methods; Aged; Aromatase Inhibitors; adverse effects; Arthralgia; complications; Breast Neoplasms; complications; Cancer Survivors; statistics & numerical data; Catechol O-Methyltransferase; genetics; Female; Humans; Middle Aged; Pain Measurement; Treatment Outcome
UT PubMed:29912452
PM 29912452
DA 2018-06-19
ER

PT J
AU Miller, KR
   Patel, JN
   Symanowski, JT
   Edelen, CA
   Walsh, D
AF Miller, Katherine R
   Patel, Jai N
   Symanowski, James T
   Edelen, Connie A
   Walsh, Declan
TI Acupuncture for Cancer Pain and Symptom Management in a Palliative Medicine
SO The American journal of hospice & palliative care
LA English
DT Journal Article
DE acupuncture; cancer; pain; palliative; supportive care; symptom
AB OBJECTIVE: Studies suggest acupuncture improves cancer-related symptoms; however,  it is unclear whether patient characteristics predict pain response. This study  determined acupuncture's effect on cancer-related pain and identified variables  associated with pain response. METHODS: A retrospective chart review included  adult patients with cancer referred to palliative medicine and received  acupuncture for pain management. Paired t tests compared differences in pain  scores from pre- to postacupuncture. Clinically meaningful pain improvement was  defined as ≥2-point reduction in pain score. Logistic regression was used to  evaluate associations between patient characteristics and pain improvement.  RESULTS: One hundred seventy acupuncture treatments from 68 individual patients  were studied. Significant reductions in mean pain scores were observed after the  first treatment (-1.9 ± 1.8; P < .001) and across all treatments (-1.7 ± 1.9; P <  .001). Multivariable analysis demonstrated clinically meaningful pain improvement  with higher baseline pain scores (odds ratio [OR]: 1.79, 95% confidence interval  [CI]: 1.44-2.22; P < .001) and stage III/IV disease (OR: 3.23, 95% CI: 1.11-9.40;  P < .001). There were significant improvements in anxiety, depression,  drowsiness, dyspnea, fatigue, nausea, and well-being after the first treatment  and across all treatments ( P < .001). CONCLUSIONS: Acupuncture improved  cancer-related pain and other symptoms. Those with higher baseline pain scores  and advanced disease were more likely to achieve significant pain reduction.  Improved depression and fatigue were closely related to pain reduction. Further  studies are needed to confirm pain response variables, establish durability, and  develop a personalized approach to acupuncture.
C1 1 Department of Cancer Pharmacology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
   1 Department of Cancer Pharmacology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
   2 Section of Palliative Medicine, Department of Supportive Oncology, Atrium 
   3 Department of Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
   2 Section of Palliative Medicine, Department of Supportive Oncology, Atrium Health, Charlotte, NC, USA.
   2 Section of Palliative Medicine, Department of Supportive Oncology, Atrium Health, Charlotte, NC, USA.
NR 0
TC 0
SN 1938-271
EI 
J9 Am J Hosp Palliat Care
PD OCT 6
PY 2018
VL 36
IS 4
BP 326
EP 332
DI 10.1177/1049909118804464
PG 6
WC Acupuncture Therapy; methods; Adult; Age Factors; Aged; Aged, 80 and over; Cancer Pain; complications; Fatigue; etiology; Female; Health Status; Humans; Logistic Models; Male; Mental Health; statistics & numerical data; Middle Aged; Pain Measurement; Palliative Care; methods; Retrospective Studies; Severity of Illness Index; Sex Factors
UT PubMed:30286611
PM 30286611
DA 2018-10-06
ER

PT J
AU You, X
   Wang, Y
   Wu, J
   Liu, Q
   Liu, Y
   Qian, Y
   Chen, J
   Tang, D
   Wang, D
AF You, Xiaolan
   Wang, Yuanjie
   Wu, Jian
   Liu, Qinghong
   Liu, Yanqing
   Qian, Yayun
   Chen, Jue
   Tang, Dong
   Wang, Daorong
TI Zusanli (ST36) Acupoint Injection with Neostigmine for Paralytic Postoperative
SO Journal of Cancer
LA English
DT Journal Article
DE ST36 acupoint injection; ST36 acupucture; gastric cancer; paralytic postoperative ileus
AB Background: The Zusanli (ST36) acupoint has been associated with treatment of  various gastrointestinal conditions. There have been no studies of acupuncture  therapy for paralytic postoperative ileus (PPOI). Materials and methods: Patients  with PPOI following gastrectomy for gastric cancer were randomized to receive  ST36 acupoint injection with neostigmine, gluteal intramuscular injection with  1.0 mg neostigmine, ST36 acupuncture alone, or standard therapy. The main outcome  was the effectiveness rate for recovery of peristalsis. Secondary outcomes were  time to bowel sound recovery, time to first flatus, and time to first defecation.  Tertiary outcomes were drug-related adverse events, including abdominal pain,  diarrhea, nausea, vomiting, tearing, delirium, seizure, and anxiety. Results:  ST36 acupoint injection with neostigmine and gluteal intramuscular injection of  neostigmine gave a higher rate of peristalsis recovery, and the ST36 acupoint  injection group showed significantly higher total effectiveness rate than that of  the intramuscular injection group. These interventions gave significantly shorter  times to bowel sound recovery, shorter times to first flatus and first defecation  compared with ST36 acupuncture and standard post-operative therapy (P < 0.01).  ST36 acupoint injection group gave shorter time to bowel sound recovery, shorter  time to first flatus and first defecation than those of the intramuscular  injection group (P < 0.01). Drug-related adverse events in the intramuscular  injection group were more serious than in the ST36 acupoint injection group (P <  0.05). Conclusion: ST36 acupoint injection with neostigmine is safe and effective  for treatment of PPOI.
C1 Department of Integrated Traditional Chinese and Western Medicine, Medical College of Yangzhou University. Yangzhou, Jiangsu Province, China.
   Department of Gastrointestinal Surgery, Taizhou people's Hospital, Taizhou, 
   Department of Gastrointestinal Surgery, Taizhou people's Hospital, Taizhou, Jiangsu Province, China.
   Department of Gastrointestinal Surgery, Taizhou people's Hospital, Taizhou, Jiangsu Province, China.
   Department of Gastrointestinal Surgery, Taizhou people's Hospital, Taizhou, Jiangsu Province, China.
   Department of Integrated Traditional Chinese and Western Medicine, Medical College of Yangzhou University. Yangzhou, Jiangsu Province, China.
   Department of Integrated Traditional Chinese and Western Medicine, Medical College of Yangzhou University. Yangzhou, Jiangsu Province, China.
   Department of Integrated Traditional Chinese and Western Medicine, Medical College of Yangzhou University. Yangzhou, Jiangsu Province, China.
   Department of Gastrointestinal Surgery, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou JiangsuProvince, China.
   Department of Gastrointestinal Surgery, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou JiangsuProvince, China.
NR 0
TC 0
SN 1837-966
EI 1837-966
J9 J Cancer
PD JUL 22
PY 2018
VL 9
IS 13
BP 2266
EP 2274
DI 10.7150/jca.24767
PG 8
UT PubMed:30026821
PM 30026821
DA 2018-07-22
ER

PT J
AU Mao, JJ
   Farrar, JT
AF Mao, Jun J
   Farrar, John T
TI Acupuncture for Aromatase Inhibitor-Related Joint Pain Among Breast Cancer
SO JAMA
LA English
DT Letter
C1 Memorial Sloan Kettering Cancer Center, New York, New York.
   University of Pennsylvania, Philadelphia.
NR 0
TC 0
SN 1538-359
EI 
J9 JAMA
PD DEC 5
PY 2018
VL 320
IS 21
BP 2269
EP 2270
DI 10.1001/jama.2018.16736
PG 1
WC Acupuncture Therapy; Aromatase; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Female; Humans
UT PubMed:30512092
PM 30512092
DA 2018-12-05
ER

PT J
AU Deng, G
   Bao, T
   Mao, JJ
AF Deng, Gary
   Bao, Ting
   Mao, Jun J
TI Understanding the Benefits of Acupuncture Treatment for Cancer Pain Management.
SO Oncology (Williston Park, N.Y.)
LA English
DT Review
AB This article summarizes the current evidence regarding the use of acupuncture for  pain management in cancer patients. It includes a description of how acupuncture  is thought to work and what the intervention entails, data on acupuncture for  managing pain caused by cancer or by cancer treatment (radiation, chemotherapy,  endocrine therapy), how acupuncture is practiced in the US medical system,  discussion of safety issues, and practical tips on how to integrate acupuncture  into cancer care.
NR 0
TC 0
SN 
EI 0890-909
J9 Oncology (Williston Park)
PD JUN 26
PY 2018
VL 32
IS 6
BP 310
EP 6
DI 
PG -304
WC Acupuncture Therapy; methods; Antineoplastic Agents; adverse effects; Aromatase Inhibitors; adverse effects; Arthralgia; etiology; Cancer Pain; therapy; Humans; Musculoskeletal Diseases; etiology; Neoplasms; drug therapy; Pain Management; methods; Peripheral Nervous System Diseases; etiology
UT PubMed:29940063
PM 29940063
DA 2018-06-26
ER

PT J
AU Mohanty, S
   Panigrahi, MK
   Turuk, J
   Dhal, S
AF Mohanty, Srujana
   Panigrahi, Manas Kumar
   Turuk, Jyotirmayee
   Dhal, Sagarika
TI Liver Abscess due to Streptococcus constellatus in an Immunocompetent Adult: A
SO Journal of the National Medical Association
LA English
DT Journal Article
DE Hepatic abscess; Liver abscess; Pyogenic liver abscess; Streptococcus constellatus
AB BACKGROUND: Pyogenic liver abscesses (PLAs) are an uncommon, but potentially life  threatening infection. We report a case of PLA due to Streptococcus constellatus,  a member of the Streptococcus anginosus group (SAG) bacteria, commonly found as  commensals of the oropharyngeal, gastrointestinal and genitourinary flora. CASE:  The patient, a 42-year-old man with no premorbidities, non-smoker and  non-alcoholic, presented to our hospital with high-grade fever associated with  chills and rigors and right upper quadrant pain of one month duration. Culture of  the ultrasound-guided liver aspirate yielded a pure growth of S. constellatus  subspecies constellatus identified by conventional biochemical tests. In a  standard antimicrobial disk-diffusion test, the isolate was susceptible to  cefepime, cefotaxime, ceftriaxone, vancomcyin, levofloxacin, clindamycin and  linezolid. Treatment with parenteral ceftriaxone alongwith appropriate surgical  management led to resolution of the abscess with no recurrence of infection at  three months follow-up. CONCLUSIONS: The pathogenic potential of SAG has  generally been disregarded because of the commensal nature of these  microorganisms; however, streptococci belonging to this group have been  increasingly reported as relevant pathogens in abscesses and blood cultures. An  underlying condition, such as diabetes, cirrhosis or cancer or some medical  manipulation, such as dental extraction, acupuncture, or hemorrhoidectomy is  associated with the majority of patients with SAG abscess. However, the present  case highlights the need to include S. constellatus and other members of the SAG  while investigating for etiology of PLA, even in immunocompetent adults.
C1 Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, 751019, Odisha, India. 
   Department of Gastroenterology, All India Institute of Medical Sciences, Bhubaneswar, 751019, Odisha, India.
   Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, 751019, Odisha, India.
   Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, 751019, Odisha, India.
EM srujana_micro@yahoo.co.in
NR 0
TC 0
SN 
EI 0027-968
J9 J Natl Med Assoc
PD AUG 22
PY 2018
VL 110
IS 6
BP 591
EP 595
DI 10.1016/j.jnma.2018.03.006
PG 4
WC Adult; Anti-Bacterial Agents; pharmacology; Ceftriaxone; pharmacology; Disk Diffusion Antimicrobial Tests; Humans; Immunocompetence; Liver Abscess; drug therapy; Male; Streptococcal Infections; complications; Streptococcus constellatus; drug effects
UT PubMed:30129495
PM 30129495
DA 2018-08-22
ER

PT J
AU Bao, T
   Li, SQ
   Dearing, JL
   Piulson, LA
   Seluzicki, CM
   Sidlow, R
   Mao, JJ
AF Bao, Ting
   Li, Susan Q
   Dearing, Josh L
   Piulson, Lauren A
   Seluzicki, Christina M
   Sidlow, Robert
   Mao, Jun J
TI Acupuncture versus medication for pain management: a cross-sectional study of
SO Acupuncture in medicine : journal of the British Medical Acupuncture Society
LA English
DT Journal Article
DE acupuncture; complementary medicine; oncology; pain management
AB AIM OF THE STUDY: Breast cancer survivors who take aromatase inhibitors (AI)  often suffer from chronic pain. Emerging evidence supports the use of acupuncture  as an effective pain management strategy for this condition, but its  acceptability among cancer survivors is unknown. We evaluated breast cancer  survivors' preferences for acupuncture as compared with medication use and  identified factors predictive of this preference. METHODS: We conducted a  cross-sectional study among breast cancer survivors who were currently, or had  been, taking an AI. The primary outcome was degree of preference for acupuncture  as compared with medication for pain management. We conducted multivariate  logistic regression analyses to evaluate the effects of socioeconomic status  (SES) factors and health beliefs on treatment preference. RESULTS: Among 592  participants, 160 (27.0%) preferred acupuncture, 153 (25.8%) preferred medication  and 279 (47.1%) had no clear preference. In a multivariate analysis that only  included SES, higher education and white race were significantly associated with  greater preference for acupuncture. When health beliefs were added, SES effects  were attenuated, while greater expectation of acupuncture's effect, lower  perceived barriers to its use, higher social norm (endorsement from family  members and healthcare professionals) related to acupuncture and higher holistic  health beliefs were associated with greater preference for acupuncture.  CONCLUSION: We found similar rates of preference for acupuncture versus  medication among breast cancer survivors for pain management. Specific attitudes  and beliefs predicted such preferences, highlighting the importance of a  patient-centred approach to align patient beliefs and preferences with  therapeutic options for more effective pain management. TRIAL REGISTRATION  NUMBER: NCT01013337; Results.
C1 Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA.
   Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA.
   Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA.
   Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA.
   Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA.
   Division of Survivorship and Supportive Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
   Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA.
NR 0
TC 0
SN 1759-987
EI 0964-528
J9 Acupunct Med
PD FEB 15
PY 2018
VL 36
IS 2
BP 80
EP 87
DI 10.1136/acupmed-2017-011435
PG 7
WC Acupuncture Therapy; Adult; Aged; Aged, 80 and over; Aromatase Inhibitors; therapeutic use; Breast Neoplasms; complications; Cancer Survivors; psychology; Chronic Pain; drug therapy; Cross-Sectional Studies; Culture; Female; Humans; Longitudinal Studies; Middle Aged; Pain; drug therapy; Patient Preference; Prospective Studies
UT PubMed:29440043
PM 29440043
DA 2018-02-15
ER

PT J
AU Hall, M
   Bifano, SM
   Leibel, L
   Golding, LS
   Tsai, SL
AF Hall, Missy
   Bifano, Susanne M.
   Leibel, Leigh
   Golding, Linda S.
   Tsai, Shiu-Lin
TI The Elephant in the Room: The Need for Increased Integrative Therapies in Conventional Medical Settings
SO CHILDREN-BASEL
LA English
DT Article
DE Integrative therapies; art therapy; music therapy; yoga therapy; acupuncture; pastoral care; creative arts therapy; pediatrics
ID chemotherapy-induced nausea; quality-of-life; pediatric oncology; breast-cancer; acupuncture; multicenter; yoga; pain
AB Pediatric integrative therapy programs are essential to the treatment and well-being of patients. Identifying an effective integrative therapy model within conventional pediatric medical settings, however, often proves difficult. Our goal in this article is to explore varied solutions to increase access and inclusion of integrative therapies in an effort to promote best practice and holistic care. The main methods applied in this article are vignettes that illustrate how the integrative therapies in a metropolitan academic hospital successfully treat the patient by complementing conventional medicine. This leads to comprehensive care. The central finding of the article proposes viable solutions to increase interdisciplinary collaboration both internally within the institution and externally. Integrative therapists detail how they were able to increase visibility and yield best practice through increased educational initiatives and interdisciplinary collaboration.
C1 [Hall, Missy; Bifano, Susanne M.] Columbia Univ, NewYork Presbyterian Morgan Stanley Childrens Hos, Child Life Dept, Med Ctr, 3959 Broadway, New York, NY 10032 USA.
   [Leibel, Leigh] Columbia Univ, Med Ctr, Div Hematol Oncol, 161 Ft Washington Ave,Suite 922, New York, NY 10032 USA.
   [Golding, Linda S.] Columbia Univ, Med Ctr, NewYork Presbyterian Milstein, Pastoral Care, 622 W 168th St, New York, NY 10032 USA.
   [Tsai, Shiu-Lin] Columbia Univ Coll Phys & Surg, Dept Emergency Med, Div Pediat Emergency Med, 3959 Broadway,CHN-W116, New York, NY 10032 USA.
C3 Cornell University; Weill Cornell Medicine; NewYork-Presbyterian Hospital; Morgan Stanley Children's Hospital; Columbia University; Columbia University; Columbia University; Columbia University
RP Hall, M (corresponding author), Columbia Univ, NewYork Presbyterian Morgan Stanley Childrens Hos, Child Life Dept, Med Ctr, 3959 Broadway, New York, NY 10032 USA.
EM mmh9010@nyp.org; sub9053@nyp.org; LL3125@cumc.columbia.edu; lig9048@nyp.org; st166@cumc.columbia.edu
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NR 43
TC 4
Z9 6
U1 0
U2 23
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 
EI 2227-9067
J9 CHILDREN-BASEL
JI Children-Basel
PD NOV 15
PY 2018
VL 5
IS 11
BP 
EP 
DI 10.3390/children5110154
PG 13
WC Pediatrics
SC Pediatrics
GA HB8BJ
UT WOS:000451308700012
PM 30453586
DA 2026-01-16
ER

PT J
AU You, XL
   Wang, YJ
   Wu, J
   Liu, QH
   Liu, YQ
   Qian, YY
   Chen, J
   Tang, D
   Wang, DR
AF You, Xiaolan
   Wang, Yuanjie
   Wu, Jian
   Liu, Qinghong
   Liu, Yanqing
   Qian, Yayun
   Chen, Jue
   Tang, Dong
   Wang, Daorong
TI Zusanli (ST36) Acupoint Injection with Neostigmine for Paralytic Postoperative Ileus following Radical Gastrectomy for Gastric Cancer: a Randomized Clinical Trial
SO JOURNAL OF CANCER
LA English
DT Article
DE gastric cancer; paralytic postoperative ileus; ST36 acupucture; ST36 acupoint injection
ID gastrointestinal motility disorders; chewing gum; laparoscopic surgery; enhanced recovery; risk-factors; acupuncture; chemotherapy; symptoms; pathways; care
AB Background: The Zusanli (ST36) acupoint has been associated with treatment of various gastrointestinal conditions. There have been no studies of acupuncture therapy for paralytic postoperative ileus (PPOI). Materials and methods: Patients with PPOI following gastrectomy for gastric cancer were randomized to receive ST36 acupoint injection with neostigmine, gluteal intramuscular injection with 1.0 mg neostigmine, ST36 acupuncture alone, or standard therapy. The main outcome was the effectiveness rate for recovery of peristalsis. Secondary outcomes were time to bowel sound recovery, time to first flatus, and time to first defecation. Tertiary outcomes were drug-related adverse events, including abdominal pain, diarrhea, nausea, vomiting, tearing, delirium, seizure, and anxiety. Results: ST36 acupoint injection with neostigmine and gluteal intramuscular injection of neostigmine gave a higher rate of peristalsis recovery, and the ST36 acupoint injection group showed significantly higher total effectiveness rate than that of the intramuscular injection group. These interventions gave significantly shorter times to bowel sound recovery, shorter times to first flatus and first defecation compared with ST36 acupuncture and standard post-operative therapy (P < 0.01). ST36 acupoint injection group gave shorter time to bowel sound recovery, shorter time to first flatus and first defecation than those of the intramuscular injection group (P < 0.01). Drug-related adverse events in the intramuscular injection group were more serious than in the ST36 acupoint injection group (P < 0.05). Conclusion: ST36 acupoint injection with neostigmine is safe and effective for treatment of PPOI.
C1 [You, Xiaolan; Liu, Yanqing; Qian, Yayun; Chen, Jue] Yangzhou Univ, Med Coll, Dept Integrated Tradit Chinese & Western Med, Yangzhou, Jiangsu, Peoples R China.
   [You, Xiaolan; Wang, Yuanjie; Wu, Jian; Liu, Qinghong] Taizhou Peoples Hosp, Dept Gastrointestinal Surg, Taizhou, Jiangsu, Peoples R China.
   [Tang, Dong; Wang, Daorong] Yangzhou Univ, Subei Peoples Hosp Jiangsu Prov, Clin Med Coll, Dept Gastrointestinal Surg, Yangzhou 225000, Jiangsu, Peoples R China.
C3 Yangzhou University; Yangzhou University
RP Wang, DR (corresponding author), Yangzhou Univ, Subei Peoples Hosp Jiangsu Prov, Clin Med Coll, Dept Gastrointestinal Surg, Yangzhou 225000, Jiangsu, Peoples R China.
EM wdaorong666@sina.com
FU National Natural Science Foundation of China [81172279, 81572343]
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NR 36
TC 23
Z9 31
U1 2
U2 41
PU IVYSPRING INT PUBL
PI LAKE HAVEN
PA PO BOX 4546, LAKE HAVEN, NSW 2263, AUSTRALIA
SN 1837-9664
EI 
J9 J CANCER
JI J. Cancer
PD JUN 15
PY 2018
VL 9
IS 13
BP 2266
EP 2274
DI 10.7150/jca.24767
PG 9
WC Oncology
SC Oncology
GA GJ3BH
UT WOS:000435149400004
PM 30026821
DA 2026-01-16
ER

PT J
AU Liu, C
   Zhang, H
   Sun, CG
AF Liu, Cun
   Zhang, Heng
   Sun, Changgang
TI Acupuncture for Aromatase Inhibitor-Related Joint Pain Among Breast Cancer Patients
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Letter
ID sham acupuncture; women
C1 [Liu, Cun; Zhang, Heng] Shandong Univ Tradit Chinese Med, Coll Tradit Chinese Med, Jinan, Shandong, Peoples R China.
   [Sun, Changgang] Weifang Tradit Chinese Hosp, Weifang, Peoples R China.
C3 Shandong University of Traditional Chinese Medicine
RP Sun, CG (corresponding author), Weifang Tradit Chinese Hosp, Dept Tradit Chinese Med Oncol, Weifang 261000, Peoples R China.
EM zhongliuyike@163.com
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NR 5
TC 3
Z9 3
U1 0
U2 29
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD DEC 4
PY 2018
VL 320
IS 21
BP 2270
EP 2270
DI 10.1001/jama.2018.16740
PG 1
WC Medicine, General & Internal
SC General & Internal Medicine
GA HD4MB
UT WOS:000452500600022
PM 30512093
DA 2026-01-16
ER

PT J
AU Jang, CE
   Jung, MS
   Sohn, EH
   Kim, M
   Yoo, HS
   Bae, K
   Kim, JR
   Lee, JS
AF Jang, Chang Eun
   Jung, Mi Sook
   Sohn, Eun Hee
   Kim, Mijung
   Yoo, Hwa-Seung
   Bae, Kyeore
   Kim, Je Ryong
   Lee, Jin Sun
TI The evaluation of changes in peripheral neuropathy and quality-of-life using low-frequency electrostimulation in patients treated with chemotherapy for breast cancer: a study protocol
SO TRIALS
LA English
DT Article
DE Chemotherapy-induced peripheral neuropathy; Health-related quality of life; Low-frequency electrostimulation device; Breast cancer
ID functional-assessment; symptom management; scrambler therapy; fact-b; pain; acupuncture; validity; neurotoxicity; reliability; validation
AB Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, enduring, and sometimes irreversible neurotoxic symptom that occurs in 30-40% of chemotherapy-treated cancer patients. CIPN negatively affects both the patient's abilities to perform daily activities and their health-related quality of life (HRQOL) after chemotherapy treatment. Although this neuropathy has been treated with duloxetine and/or gabapentin, limited therapeutic benefits have been reported, thereby necessitating the development of an integrated approach that combines pharmacological management and complementary methods such as acupuncture and electric nerve stimulation. Therefore, this study is designed to examine the effect of a portable, low-frequency electrostimulation (ES) device on CIPN symptoms and HRQOL of female patients diagnosed with CIPN immediately after chemotherapy for breast cancer. Methods: This study is a single-center, randomized, placebo-controlled trial with two parallel groups and a 2-week follow-up. We will enroll 80 breast cancer patients who are newly diagnosed with CIPN after chemotherapy. Duloxetine or pregabalin will be prescribed to all participants from the initial assessment. Half of the patients will be assigned into the experimental group and the other half to the control group. The CarebandR (Piomed Inc., Seoul, Korea), a wearable wristband that generates low-frequency electrostimulation, will be administered only to the experimental group. Electrostimulation will be administered on the unilateral PC6 acupoint. A numerical rating scale will be used to assess the overall intensity of CIPN symptoms. The key secondary outcome variables include patient-reported CIPN symptom distress tested by a self-rated questionnaire, physician-rated symptom severity assessed by the Total Neuropathy Score, and HRQOL. Discussion: It is expected that the combination of a low-frequency electrostimulation device and pharmacological intervention (duloxetine or pregabalin) will produce synergistic effects in breast cancer patients with CIPN after treatment. To our knowledge, this is the first study to investigate the beneficial effect of a new integrated approach for CIPN management after breast cancer treatment. The study findings can expand our knowledge and understanding of the occurrence of CIPN and the efficacy of integrated intervention efforts to ameliorate CIPN symptoms.
C1 [Jang, Chang Eun] Yonsei Univ, Coll Med, Dept Surg, Seoul, South Korea.
   [Jung, Mi Sook; Kim, Mijung] Chungnam Natl Univ, Coll Nursing, Daejeon, South Korea.
   [Sohn, Eun Hee] Chungnam Natl Univ Hosp, Dept Neurol, Daejeon, South Korea.
   [Yoo, Hwa-Seung; Bae, Kyeore] Daejeon Univ, East West Canc Ctr, Dunsan Korean Med Hosp, Daejeon, South Korea.
   [Kim, Je Ryong; Lee, Jin Sun] Chungnam Natl Univ, Coll Med, Dept Surg, 33 Munwha Ro, Daejeon, South Korea.
   [Kim, Je Ryong; Lee, Jin Sun] Chungnam Natl Univ, Coll Med, Res Inst Med Sci, 33 Munwha Ro, Daejeon, South Korea.
C3 Yonsei University; Yonsei University Health System; Chungnam National University; Chungnam National University; Chungnam National University Hospital; Daejeon University; Chungnam National University; Chungnam National University
RP Lee, JS (corresponding author), Chungnam Natl Univ, Coll Med, Dept Surg, 33 Munwha Ro, Daejeon, South Korea.; Lee, JS (corresponding author), Chungnam Natl Univ, Coll Med, Res Inst Med Sci, 33 Munwha Ro, Daejeon, South Korea.
EM leejin123@hanmail.net
FU Ministry of Health and Welfare, Republic of Korea [HI15C0007]
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NR 55
TC 8
Z9 10
U1 1
U2 20
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 
EI 1745-6215
J9 TRIALS
JI Trials
PD SEP 29
PY 2018
VL 19
IS 
BP 
EP 
DI 10.1186/s13063-018-2874-2
PG 9
WC Medicine, Research & Experimental
SC Research & Experimental Medicine
GA GV2MI
UT WOS:000445923700001
PM 30268158
DA 2026-01-16
ER

PT J
AU Scarborough, BM
   Smith, CB
AF Scarborough, Bethann M
   Smith, Cardinale B
TI Optimal pain management for patients with cancer in the modern era.
SO CA: a cancer journal for clinicians
LA English
DT Review
DE addiction; adjuvant; cancer; opioid; pain assessment; pain management
AB Pain is a common symptom among patients with cancer. Adequate pain assessment and  management are critical to improve the quality of life and health outcomes in  this population. In this review, the authors provide a framework for safely and  effectively managing cancer-related pain by summarizing the evidence for the  importance of controlling pain, the barriers to adequate pain management,  strategies to assess and manage cancer-related pain, how to manage pain in  patients at risk of substance use disorder, and considerations when managing pain  in a survivorship population. CA Cancer J Clin 2018;68:182-196. © 2018 American  Cancer Society.
C1 Assistant Professor, Brookdale Department of Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai, New York, NY.
   Associate Professor of Medicine, Division of Hematology and Medical Oncology, Brookdale Department of Geriatrics and Palliative Care, Icahn School of Medicineat Mount Sinai, New York, NY.
   Director of Quality for Cancer Services, Mount Sinai Health System, Tisch Cancer
NR 0
TC 0
SN 1542-486
EI 0007-923
J9 CA Cancer J Clin
PD APR 1
PY 2018
VL 68
IS 3
BP 182
EP 196
DI 10.3322/caac.21453
PG 14
WC Acupuncture Therapy; Analgesics, Non-Narcotic; therapeutic use; Analgesics, Opioid; therapeutic use; Anticonvulsants; therapeutic use; Antidepressive Agents; therapeutic use; Cancer Pain; diagnosis; Delayed-Action Preparations; Healthcare Disparities; Humans; Injections, Epidural; Injections, Spinal; Medical Marijuana; therapeutic use; Mindfulness; Nerve Block; Pain Measurement; Prescription Drug Misuse; Quality of Life; Radiotherapy; Substance-Related Disorders; diagnosis
UT PubMed:29603142
PM 29603142
DA 2018-04-01
ER

PT J
AU García, Espinosa MV
   Prieto, Checa I
AF García Espinosa, María Victoria
   Prieto Checa, Isabel
TI [Non-oncologic chronic pain: Where we are and where we want to go].
SO Atencion primaria
LA spa
DT Editorial
C1 Medicina Familiar y Comunitaria, Centro de Salud Los Alpes, Madrid, España. 
   Medicina Familiar y Comunitaria, Centro de Salud Los Alpes, Madrid, España.
EM vgespinosa@gmail.com
NR 0
TC 0
SN 1578-127
EI 0212-656
J9 Aten Primaria
PD MAY 8
PY 2018
VL 50
IS 9
BP 517
EP 518
DI 10.1016/j.aprim.2017.12.006
PG 1
WC Acupuncture Therapy; Chronic Pain; drug therapy; Humans; Mind-Body Therapies; Opioid-Related Disorders; etiology; Pain Management; adverse effects; Prescription Drug Overuse; mortality; Spain
UT PubMed:29735179
PM 29735179
DA 2018-05-08
ER

PT J
AU Zhi, WI
   Ingram, E
   Li, SQ
   Chen, P
   Piulson, L
   Bao, T
AF Zhi, W. Iris
   Ingram, Evan
   Li, Susan Qing
   Chen, Patricia
   Piulson, Lauren
   Bao, Ting
TI Acupuncture for Bortezomib-Induced Peripheral Neuropathy: Not Just for Pain
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE acupuncture; bortezomib; multiple myeloma; peripheral neuropathy
ID small fiber neuropathy; multiple-myeloma; oncology-group; breast-cancer; chemotherapy; trial; activation; mechanisms; prevention; receptors
AB Background: Bortezomib-induced peripheral neuropathy (BIPN) is a common and debilitating side effect. Our pilot study demonstrated that acupuncture is safe and can decrease total neuropathic symptoms. However, there is lack of knowledge in which individual BIPN symptoms benefited from acupuncture. Purpose: To characterize individual symptoms reduced by acupuncture in patients with BIPN. Methods: Patients with multiple myeloma treated with bortezomib who developed BIPN grade 2 or above, based on National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE), were enrolled and received 10 acupuncture treatments over 10 weeks. Self-reported BIPN-associated symptoms assessments were collected weekly at baseline, during, and after acupuncture treatment using the Neuropathy Pain Scale (NPS) and the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (FACT/GOG-Ntx) questionnaires. Changes in individual symptoms were analyzed based on FACT/GOG-Ntx and NPS scores. Results: There were statistically significant reductions in individual symptoms in both NPS and FACT/GOG-Ntx. The FACT/GOG-Ntx reductions were most pronounced in hand/feet numbness/tingling, discomfort, and trouble walking. The sensory symptoms, such as tingling and numbness, especially in the feet, reduced the most (P < .0001), and motor dysfunction also reduced significantly (P = .0001). Both hearing and dysfunction scores were also statistically significantly increased, indicating improved symptoms. The NPS scores showed significant symptom relief in all 10 items from the NPS assessment, particularly in cold sensitivity and an unpleasant feeling. Conclusions: Acupuncture can improve multiple symptoms associated with BIPN, particularly numbness and tingling in hands and feet, cold sensitivity, and an unpleasant feeling. Further randomized control trials are warranted to confirm our findings.
C1 [Zhi, W. Iris; Li, Susan Qing; Chen, Patricia; Piulson, Lauren; Bao, Ting] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA.
   [Ingram, Evan] Univ Toledo, 2801 W Bancroft St, Toledo, OH 43606 USA.
C3 Memorial Sloan Kettering Cancer Center; University System of Ohio; University of Toledo
RP Bao, T (corresponding author), Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1429 First Ave, New York, NY 10021 USA.
EM baot@mskcc.org
FU Memorial Sloan Kettering Cancer Center P30 Grant [P30-CA008748];  [R21CA173263]; National Cancer Institute [P30CA008748] Funding Source: NIH RePORTER
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NR 33
TC 28
Z9 37
U1 1
U2 20
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD DEC 15
PY 2018
VL 17
IS 4
BP 1079
EP 1086
DI 10.1177/1534735418788667
PG 8
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA HA5OG
UT WOS:000450322400008
PM 30027756
DA 2026-01-16
ER

PT J
AU Xu, LL
   Wan, YX
   Huang, J
   Xu, FY
AF Xu, Lili
   Wan, Yongxian
   Huang, Juan
   Xu, Fangyuan
TI Clinical analysis of electroacupuncture and multiple acupoint stimulation in relieving cancer pain in patients with advanced hepatocellular carcinoma
SO JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
LA English
DT Article
DE Cancerous pain; electroacupuncture; hepatocellular carcinoma; multiple acupoint stimulation; pain relief
ID acupuncture; management
AB Objective: The objective of this study is to investigate the clinical efficacy and safety of electroacupuncture and multiple acupoint stimulation in relieving cancer pain in patients with advanced hepatocellular carcinoma. Methods: Sixty-five cases of advanced hepatocellular carcinoma with cancer pain were selected in our hospital and were divided into electroacupuncture multiple acupoint stimulation group (electroacupuncture group) (n = 32) and fentanyl transdermal patch analgesia group (control group) (n = 33) according to analgesic methods and intentions. In the electroacupuncture group, electric acupuncture treatment was administered at different acupoints, including Baihui, Quchi, Neiguan, Xuehai, Zusanli, and Sanyinjiao acupoint, once a day for 7 days. In the control group, a fentanyl transdermal patch was placed on the upper left arm every 3 days and replaced with a continuous external paste once for 7 days. Pain scores in the two groups before and during the treatment were evaluated with a visual analog scale (VAS), and adverse reactions during the treatment were recorded. Results: The VAS pain score of the electroacupuncture group was significantly decreased on day 3 (P < 0.05), but the pain scores were not significantly different (P > 0.05) between the two groups 4 days after treatment. For treatment-related side effects, there were 3 cases of subcutaneous hemorrhage in the electroacupuncture group; 1 case of skin rashes and 3 cases of nausea and vomiting in the control group. The incidences of adverse reactions in the two groups were 9.4% and 12.1%, respectively, without significant difference (P > 0.05). Conclusion: Cancer pain in patients with advanced hepatocellular carcinoma can be alleviated with electroacupuncture and multiple acupoint stimulation, but the onset pain relief was slow. To improve the analgesic effects of this technique, the combination of various analgesic methods should be necessary in early stage of the treatment.
C1 [Xu, Lili; Huang, Juan; Xu, Fangyuan] Southwest Med Univ, Affiliated Hosp, Dept Rehabil, Luzhou 646000, Peoples R China.
   [Wan, Yongxian] Southwest Med Univ, Affiliated Hosp, Dept Bone & Joint Surg, Luzhou, Peoples R China.
C3 Southwest Medical University; Southwest Medical University
RP Xu, LL (corresponding author), Southwest Med Univ, Affiliated Hosp, Dept Rehabil, Luzhou 646000, Peoples R China.
EM 171714336@qq.com
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NR 16
TC 13
Z9 18
U1 2
U2 15
PU WOLTERS KLUWER MEDKNOW PUBLICATIONS
PI MUMBAI
PA WOLTERS KLUWER INDIA PVT LTD , A-202, 2ND FLR, QUBE, C T S  NO 1498A-2 VILLAGE MAROL, ANDHERI EAST, MUMBAI, 400059, INDIA
SN 0973-1482
EI 1998-4138
J9 J CANCER RES THER
JI J. Canc. Res. Ther.
PD JAN 15
PY 2018
VL 14
IS 1
BP 99
EP 102
DI 10.4103/jcrt.JCRT_736_17
PG 4
WC Oncology
SC Oncology
GA FZ1WL
UT WOS:000427368100019
PM 29516968
DA 2026-01-16
ER

PT J
AU Zhang, B
   Xu, F
   Hu, PP
   Zhang, MY
   Tong, KH
   Ma, G
   Xu, YM
   Zhu, L
   Chen, JDDZ
AF Zhang, Bo
   Xu, Feng
   Hu, Pingping
   Zhang, Mingyuan
   Tong, Kehui
   Ma, Gang
   Xu, Yuemei
   Zhu, Liang
   Chen, Jiande D. Z.
TI Needleless Transcutaneous Electrical Acustimulation: A Pilot Study Evaluating Improvement in Post-Operative Recovery
SO AMERICAN JOURNAL OF GASTROENTEROLOGY
LA English
DT Article
ID heart-rate-variability; gastrointestinal motility; functional dyspepsia; laparoscopic surgery; induced impairment; rectal distension; vagus nerve; electroacupuncture; ileus; acupuncture
AB BACKGROUND: Functional gastrointestinal disturbance occurs after abdominal surgeries and could last for an extended period of time in some cases. This study was designed (1) to evaluate the effects of needleless transcutaneous electrical acustimulation (TEA) on postoperative recovery, and (2) to investigate the mechanisms involving autonomic function in postoperative patients after removal of gastrointestinal cancers. METHODS: Forty-two patients (33 male, age: 69.5 +/- 1.5 years) scheduled for abdominal surgical removal of gastrointestinal cancers were randomized to TEA (n = 21) and sham-TEA (n = 21). TEA was performed via acupoints ST36 and PC6 1 h twice daily from the postoperative day (POD) 1 to day 3. Sham-TEA was performed at non-acupoints. RESULTS: (1) TEA improved major postoperative symptoms by about 30%, including a reduction in time to defecation by 31.7% (P < 0.01 vs. sham-TEA), time to first flatus by 35.9% (P < 0.001), time to ambulation by 42.8% (P < 0.01), time to resuming diet by 26.5% (P < 0.01) and hospital stay by 30% (P < 0.05) as well as pain score by 50% (P < 0.01). (2) TEA significantly increased vagal activity (P < 0.001) and decreased sympathetic activity on POD 4 (P < 0.001) compared with POD 1 as well as the serum level of NE (P < 0.05). (3) The vagal activity, high frequency assessed from the spectral analysis of heart rate variability, was negatively correlated with time to resuming diet, whereas the sympathetic measurement, serum norepinephrine was positively correlated with time to resuming diet and time to flatus. (4) TEA but not sham-TEA decreased TNF-alpha by 17.4% from POD 1 to POD 4. (5) TEA was an independent predictor of a shorter hospital stay. CONCLUSIONS: Needleless TEA improves major postoperative symptoms by enhancing vagal and suppressing sympathetic activities.
C1 [Zhang, Bo; Zhu, Liang] Second Mil Med Univ, Changzheng Hosp, Dept Gastroenterol, Shanghai 200003, Peoples R China.
   [Zhang, Bo; Ma, Gang; Chen, Jiande D. Z.] Ningbo Pace Translat Med Res Ctr, Ningbo, Zhejiang, Peoples R China.
   [Xu, Feng; Hu, Pingping; Xu, Yuemei] Ningbo Univ, Sch Med, Yinzhou Hosp, Div Gastroenterol, Ningbo, Zhejiang, Peoples R China.
   [Zhang, Mingyuan; Tong, Kehui] Ningbo Univ, Sch Med, Yinzhou Hosp, Gastroenterol Surg Dept, Ningbo, Zhejiang, Peoples R China.
   [Ma, Gang] Nanjing Med Univ, Huaian Peoples Hosp 1, Dept Gastroenterol, Huaian, Jiangsu, Peoples R China.
   [Chen, Jiande D. Z.] Johns Hopkins Ctr Neurogastroenterol, Div Gastroenterol & Hepatol, Baltimore, MD 21224 USA.
C3 Naval Medical University; Ningbo University; Ningbo University; Nanjing Medical University; Johns Hopkins University; Johns Hopkins Medicine
RP Zhu, L (corresponding author), Second Mil Med Univ, Changzheng Hosp, Dept Gastroenterol, Shanghai 200003, Peoples R China.; Chen, JDDZ (corresponding author), Ningbo Pace Translat Med Res Ctr, Ningbo, Zhejiang, Peoples R China.; Chen, JDDZ (corresponding author), Johns Hopkins Ctr Neurogastroenterol, Div Gastroenterol & Hepatol, Baltimore, MD 21224 USA.
EM czzhuliang@smmu.edu.cn; jchen184@jhmi.edu
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NR 63
TC 45
Z9 57
U1 0
U2 37
PU NATURE PUBLISHING GROUP
PI NEW YORK
PA 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA
SN 0002-9270
EI 1572-0241
J9 AM J GASTROENTEROL
JI Am. J. Gastroenterol.
PD JUL 15
PY 2018
VL 113
IS 7
BP 1026
EP 1035
DI 10.1038/s41395-018-0156-y
PG 10
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA GR3KF
UT WOS:000442487800019
PM 29925916
DA 2026-01-16
ER

PT J
AU Mao, JJ
   Farrar, JT
AF Mao, Jun J.
   Farrar, John T.
TI Acupuncture for Aromatase Inhibitor-Related Joint Pain Among Breast Cancer Patients
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Letter
C1 [Mao, Jun J.] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA.
   [Farrar, John T.] Univ Penn, Philadelphia, PA 19104 USA.
C3 Memorial Sloan Kettering Cancer Center; University of Pennsylvania
RP Mao, JJ (corresponding author), Mem Sloan Kettering Canc Ctr, Bendheim Integrat Med Ctr, 1429 First Ave, New York, NY 10021 USA.
EM maoj@mskcc.org
FU Office of Diversity, Inclusion, Community Engagement, and Equity at the Yale School of Medicine
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NR 4
TC 1
Z9 2
U1 0
U2 23
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD DEC 4
PY 2018
VL 320
IS 21
BP 2269
EP 2270
DI 10.1001/jama.2018.16736
PG 2
WC Medicine, General & Internal
SC General & Internal Medicine
GA HD4MB
UT WOS:000452500600021
PM 30512092
DA 2026-01-16
ER

PT J
AU Cherniack, EP
   Govorushko, S
AF Cherniack, E. Paul
   Govorushko, Sergey
TI To bee or not to bee: The potential efficacy and safety of bee venom acupuncture in humans
SO TOXICON
LA English
DT Review
DE Efficacy; Safety; Bee venom acupuncture
ID neuropathic cold allodynia; acupoint stimulation; fos expression; formalin test; cancer cells; pain; melittin; pharmacopuncture; apipuncture; injection
AB Bee venom acupuncture is a form of acupuncture in which bee venom is applied to the tips of acupuncture needles, stingers are extracted from bees, or bees are held with an instrument exposing the stinger, and applied to acupoints on the skin. Bee venom is a complex substance consisting of multiple anti-inflammatory compounds such as melittin, adolapin, apamin. Other substances such as phospholipase A2 can be anti-inflammatory in low concentrations and pro-inflammatory in others. However, bee venom also contains proinflammatory substances, melittin, mast cell degranulation peptide 401, and histamine. Nevertheless, in small studies, bee venom acupuncture has been used in man to successfully treat a number of musculoskeletal diseases such as lumbar disc disease, osteoarthritis of the knee, rheumatoid arthritis, adhesive capsulitis, and lateral epicondylitis. Bee venom acupuncture can also alleviate neurological conditions, including peripheral neuropathies, stroke and Parkinson's Disease. The treatment has even been piloted in one series to alleviate depression. An important concern is the safety of bee venom. Bee venom can cause anaphylaxis, and several deaths have been reported in patients who successfully received the therapy prior to the adverse event. While the incidence of adverse events is unknown, the number of published reports of toxicity is small. Refining bee venom to remove harmful substances may potentially limit its toxicity. New uses for bee venom acupuncture may also be considered.
C1 [Cherniack, E. Paul] Univ Miami, Miller Sch Med, Miami VA Med Ctr, Div Geriatr & Palliat Med, Miami, FL 33136 USA.
   [Govorushko, Sergey] Russian Acad Sci, Pacific Geog Inst, Vladivostok, Russia.
   [Govorushko, Sergey] Far Eastern Fed Univ, Vladivostok, Russia.
C3 University of Miami; Russian Academy of Sciences; Pacific Geographical Institute of the Far Eastern Branch of the Russian Academy of Sciences; Far Eastern Federal University
RP Cherniack, EP (corresponding author), Miami VA Med Ctr, Room NH445,1201 NW 16 St, Miami, FL 33125 USA.
EM evan.cherniack@va.gov
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NR 74
TC 64
Z9 72
U1 2
U2 79
PU PERGAMON-ELSEVIER SCIENCE LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
SN 0041-0101
EI 
J9 TOXICON
JI Toxicon
PD NOV 15
PY 2018
VL 154
IS 
BP 74
EP 78
DI 10.1016/j.toxicon.2018.09.013
PG 5
WC Pharmacology & Pharmacy; Toxicology
SC Pharmacology & Pharmacy; Toxicology
GA GZ2TS
UT WOS:000449241900010
PM 30268393
DA 2026-01-16
ER

PT J
AU Liu, C
   Zhang, H
   Sun, C
AF Liu, Cun
   Zhang, Heng
   Sun, Changgang
TI Acupuncture for Aromatase Inhibitor-Related Joint Pain Among Breast Cancer
SO JAMA
LA English
DT Letter
C1 College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
   College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
   Weifang Traditional Chinese Hospital, Weifang, China.
NR 0
TC 0
SN 1538-359
EI 
J9 JAMA
PD DEC 5
PY 2018
VL 320
IS 21
BP 2270
EP 2270
DI 10.1001/jama.2018.16740
PG 0
WC Acupuncture Therapy; Aromatase; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Female; Humans
UT PubMed:30512093
PM 30512093
DA 2018-12-05
ER

PT J
AU Zick, S
   Schrepf, A
   Hasset, A
   Sen, A
   Harris, R
AF Zick, Suzanna
   Schrepf, Andrew
   Hasset, Afton
   Sen, Ananda
   Harris, Richard
TI Depression, anxiety, and pain as potential mediators and moderators of self-administered acupressure's effect on fatigue and sleep quality in breast cancer survivors
SO PSYCHO-ONCOLOGY
LA English
DT Meeting Abstract
C1 [Zick, Suzanna; Schrepf, Andrew; Hasset, Afton; Sen, Ananda; Harris, Richard] Univ Michigan, Ann Arbor, MI 48109 USA.
C3 University of Michigan System; University of Michigan
FU National Institutes of Health [R01 CA151445, 2UL1 TR000433-06]
NR 0
TC 1
Z9 1
U1 0
U2 8
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1057-9249
EI 1099-1611
J9 PSYCHO-ONCOLOGY
JI Psycho-Oncol.
PD FEB 15
PY 2018
VL 27
IS 
BP 74
EP 74
DI 
PG 1
WC Oncology; Psychology; Psychology, Multidisciplinary; Social Sciences, Biomedical
SC Oncology; Psychology; Biomedical Social Sciences
GA FV8OH
UT WOS:000424845700175
DA 2026-01-16
ER

PT J
AU Xie, DW
   Shi, XY
   Zhang, YX
AF Xie, Duowen
   Shi, Xiaoyuan
   Zhang, Yinxia
TI Effect of Combined Acupuncture Anesthesia on Surgical Dosage and Serum IL-4, IL-10 of Pneumonectomy Patients
SO JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
LA English
DT Article
DE Combined acupuncture anesthesia; Pneumonectomy; Propofol; Fentanyl; Interleukin-4; Interleukin-10
ID cancer; stimulation; frequency; immune; cell
AB Objective: To analyse the effects of combined acupuncture anesthesia on surgical dosage and serum interleukin-4 (IL-4), interleukin-10 (IL-10) of pneumonectomy patients. Study Design: A randomised controlled trial (RCT). Place and Duration of Study: Lanzhou University Second Hospital, Lanzhou, China, from January 2016 to November 2017. Methodology: A total of 110 patients undergoing pneumonectomy were randomly divided into group A and group B, with 55 cases in each group. Group A was treated with combined 2Hz acupuncture anesthesia, while group B was treated with combined 2Hz/100Hz acupuncture anesthesia. The additional propofol, fentanyl dosage, and changes in heart rate and systolic blood pressure 5 min before and during extubation were compared between the two groups. The serum IL-4 and IL-10 levels were measured 10 minutes after skin incision and 24 hours after surgery using ELISA. Pain was rated by visual analogue scale (VAS) at 24 hours after surgery. Results: There was no statistically significant difference between group A and group B in the intraoperative additional propofol and fentanyl dosags (p=0.541 and 0.719, respectively). There is no statistical difference in heart rate and systolic blood pressure between group A and group B at 5 minutes before and during extubation (p=0.151, 0.660 and 0.734, 0.528, respectively). There is no statistical difference between group A and group B in serum IL-4 and IL-10 levels 10 minutes after surgical incision (p=0.916 and 0.841, respectively). However, serum IL-4 and IL-2 levels in group A are statistically lower than that of group B at 24 hours after surgery (all p<0.001). The VAS score at 24 hours after surgery in group A was 2.44 +/- 0.71 points, which was significantly lower than that of group B (3.82 +/- 0.77 points, p<0.001). Conclusion: Combined 2 Hz, 2 Hz/100 Hz acupuncture anesthesia need few anesthetic dosages of propofol and fentanyl to stabilise the patient's blood pressure and heart rate when intubated under general anesthesia; but combined 2 Hz acupuncture anesthesia can reduce IL-4 and IL-10 levels during surgery stress to a greater extent than the latter, and can effectively lower patients' serum IL-4, IL-10 expression after surgery.
C1 [Xie, Duowen] Lanzhou Univ, Hosp 2, Dept Intens Care Unit, Lanzhou 730000, Gansu, Peoples R China.
   [Shi, Xiaoyuan] Lanzhou Univ, Hosp 2, Med Record, Lanzhou 730000, Gansu, Peoples R China.
   [Zhang, Yinxia] Northwest Minzu Univ Hosp, Dept Hlth, Lanzhou 730000, Gansu, Peoples R China.
C3 Lanzhou University; Lanzhou University
RP Zhang, YX (corresponding author), Northwest Minzu Univ Hosp, Dept Hlth, Lanzhou 730000, Gansu, Peoples R China.
EM pu088u@163.com
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NR 21
TC 3
Z9 4
U1 1
U2 21
PU COLL PHYSICIANS & SURGEONS PAKISTAN
PI KARACHI
PA SEVENTH CENTRAL ST, DEFENCE HOUSING AUTHORITY, KARACHI, 75500, PAKISTAN
SN 1022-386X
EI 1681-7168
J9 JCPSP-J COLL PHYSICI
JI JCPSP-J. Coll. Physicians Surg.
PD NOV 15
PY 2018
VL 28
IS 11
BP 817
EP 820
DI 10.29271/jcpsp.2018.11.817
PG 4
WC Medicine, General & Internal
SC General & Internal Medicine
GA GZ6NX
UT WOS:000449556100002
PM 30369370
DA 2026-01-16
ER

PT J
AU Kim, K
   Lee, S
AF Kim, Kyungsuk
   Lee, Sanghun
TI Intradermal Acupuncture Along with Analgesics for Pain Control in Advanced Cancer
SO Integrative cancer therapies
LA English
DT Journal Article
DE acupuncture; advanced cancer; analgesics; intradermal; pain management
AB PURPOSE: Ninety percent of patients with advanced cancer have moderate to severe  pain, and up to 70% of patients with cancer pain do not receive adequate pain  relief. This randomized controlled clinical trial was designed to determine the  feasibility and evaluate the effects and safety of intradermal acupuncture (IA)  in patients who were being administered analgesics for cancer pain. METHODS:  Advanced cancer patients experiencing pain were randomly assigned to IA or sham  IA treatment for 3 weeks (15 patients for each group), wherein the CV12,  bilateral ST25, LI4, LR3, PC06, and Ashi points were selected and stimulated.  Follow-up evaluations were conducted 3 weeks after the end of treatments. The  grade and dosage of analgesics for cancer pain, pain intensity, quality of life,  and safety were assessed. RESULTS: Twenty-seven patients (90%) completed 6-week  trial, and no serious adverse events were associated with either IA or sham IA  procedures except the transient side effect such as fatigue. Nine patients in the  IA group (64.3%) and 5 in the sham IA group (38.5%) responded to the 3-week  intervention. These patients were mostly in the nonopioid and the weak opioid  levels of the World Health Organization analgesic ladder. Self-reported pain  declined by -1.54 ± 1.45 and -1.15 ± 1.57 in the IA and sham IA groups,  respectively, with improved quality of life reported. CONCLUSIONS: IA treatment  appears feasible and safe for advanced cancer patients. It might reduce analgesic  usage in the early World Health Organization analgesic ladder stage cancer  patient, though it could not show significant outcome differences due to design  limitation of sham IA.
C1 1 Department of Medical Consilience, Graduate school, Dankook University, Yongin-si, Republic of Korea.
   1 Department of Medical Consilience, Graduate school, Dankook University, Yongin-si, Republic of Korea.
NR 0
TC 0
SN 1552-695
EI 1534-735
J9 Integr Cancer Ther
PD JUL 17
PY 2018
VL 17
IS 4
BP 1137
EP 1143
DI 10.1177/1534735418786797
PG 6
WC Acupuncture Therapy; methods; Analgesics; therapeutic use; Fatigue; therapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasms; complications; Pain; drug therapy; Pain Management; methods; Pain Measurement; methods; Pilot Projects; Quality of Life; World Health Organization
UT PubMed:30009652
PM 30009652
DA 2018-07-17
ER

PT J
AU Bosco, F
   Cidin, S
   Maceri, F
   Ghilli, M
   Roncella, M
   De, Simone L
AF Bosco, F
   Cidin, S
   Maceri, F
   Ghilli, M
   Roncella, M
   De Simone, L
TI An integrated approach with homeopathic medicine and electro-acupuncture in
SO Journal of pharmacopuncture
LA English
DT Journal Article
DE Anaesthesiology; Breast cancer; Electro-acupuncture; Homeopathy; Multidisciplinary approach
AB This study investigates the effect of a combination of homeopathic medicine and  electro-acupuncture in two patients with breast cancer and severe liver disease  who could not receive standard anaesthesia therapy due to liver problems.  Specifically, measurable and quantifiable parameters were used to evaluate  whether an integrated approach-consisting of electro-acupuncture and a  homeopathic medicine diluted above Avogadro's limit (that is, above a potency of  12CH) during the pre-surgical, surgical and post-surgical phases--can improve  general well-being of a patient undergoing breast cancer surgery. In breast  cancer surgery, we employed an integrated approach consisting of induction with  hypnotics and muscle relaxants, followed by maintenance with anaesthetic gas,  combined with a homeopathic treatment (Arnica montana 15CH and Apis mellifica  15CH) before and after surgery and an electro-acupuncture treatment performed in  the pre- and post-surgical phases without any analgesic/pain relieving  medications. Both of the patients treated with the integrated approach improved  their overall condition without need for other common pain relieving medicines.  Additionally, thanks to their rapid awakening, the patients were not relocated to  a protected area and the hospitalization was shorter. A multidisciplinary  approach incorporating homeopathic medicine and electro-acupuncture can be a  solution for patients who need or ask about a different and/or safer alternative  to the standard treatment. This approach can offer a safe, much less expensive,  non-invasive and viable alternative for such cases. Moreover it can be useful for  an opioids free anesthesia.
C1 S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust ofPisa, Via Roma 67, 56126,Pisa, Italy.
   S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust ofPisa, Via Roma 67, 56126,Pisa, Italy.
   S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust ofPisa, Via Roma 67, 56126,Pisa, Italy.
   Breast Cancer Surgical Unit, University Hospital Trust of Pisa, Via Roma 67, 56126, Pisa, Italy.
   Breast Cancer Surgical Unit, University Hospital Trust of Pisa, Via Roma 67, 56126, Pisa, Italy.
   S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust ofPisa, Via Roma 67, 56126,Pisa, Italy.
NR 0
TC 0
SN 2234-685
EI 2093-696
J9 J Pharmacopuncture
PD AUG 29
PY 2018
VL 21
IS 2
BP 126
EP 131
DI 10.3831/KPI.2018.21.016
PG 5
UT PubMed:30151314
PM 30151314
DA 2018-08-29
ER

PT J
AU Sharon, H
   Goldway, N
   Goor-Aryeh, I
   Eisenberg, E
   Brill, S
AF Sharon, Haggai
   Goldway, Noam
   Goor-Aryeh, Itay
   Eisenberg, Elon
   Brill, Silviu
TI Personal experience and attitudes of pain medicine specialists in Israel regarding the medical use of cannabis for chronic pain
SO JOURNAL OF PAIN RESEARCH
LA English
DT Article
DE cannabis; pain; survey
ID chronic noncancer pain; inhaled cannabis; marijuana; prescription; management; efficacy
AB Introduction: The scientific study of the role of cannabis in pain medicine still lags far behind the growing use driven by public approval. Accumulated clinical experience is therefore an important source of knowledge. However, no study to date has targeted physicians who actually use cannabis in their daily practice. Methods: Registered, active, board-certified pain specialists in Israel (n=79) were asked to complete a Web-based survey. The survey was developed using the Qualtrics Online Survey Software. Questions were formulated as multiple-choice questions, and these addressed three areas of interest: 1) doctors' personal experience; 2) the role of cannabis in pain medicine; and 3) cannabis medicalization and legalization. Results: Sixty-four percent of all practicing pain specialists in Israel responded. Almost all prescribe cannabis. Among them, 63% find cannabis moderately to highly effective, 56% have encountered mild or no side effects, and only 5% perceive it as significantly harmful. Common indications are neuropathic pain (65%), oncological pain (50%), arthralgias (25%), and any intractable pain (29%). Leading contraindications are schizophrenia (76%), pregnancy/breastfeeding (65%), and age <18 years (59%). Only 12% rated cannabis as more hazardous than opiates. On a personal note, 45% prefer cannabis for themselves or a family member. Lastly, 54% would like to see cannabis legalized in Israel. Conclusion: In this survey, pain clinicians experienced in prescribing cannabis over prolonged periods view it as an effective and relatively safe treatment for chronic pain, based on their own experience. Their responses suggest a possible change of paradigm from using cannabis as the last resort.
C1 [Sharon, Haggai; Brill, Silviu] Tel Aviv Sourasky Med Ctr, Inst Pain Med, Dept Anesthesiol & Crit Care Med, Tel Aviv, Israel.
   [Sharon, Haggai; Goldway, Noam] Tel Aviv Sourasky Med Ctr, Ctr Brain Funct, Wohl Inst Adv Imaging, Tel Aviv, Israel.
   [Sharon, Haggai] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel.
   [Sharon, Haggai] Guys & St Thomas Hosp, Pain Management & Neuromodulat Ctr, London, England.
   [Goor-Aryeh, Itay] Sheba Med Ctr, Pain Ctr, Tel Hashomer, Israel.
   [Eisenberg, Elon] Inst Pain Med, Rambam Hlth Care Campus, Haifa, Israel.
   [Eisenberg, Elon] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel.
   [Brill, Silviu] Ben Gurion Univ Negev, Fac Hlth Sci, Goldman Sch Med, Beer Sheva, Israel.
C3 Tel Aviv University; Sackler Faculty of Medicine; Tel Aviv Sourasky Medical Center; Tel Aviv University; Sackler Faculty of Medicine; Tel Aviv Sourasky Medical Center; Tel Aviv University; Sackler Faculty of Medicine; Guy's & St Thomas' NHS Foundation Trust; Chaim Sheba Medical Center; Tel Aviv University; Rambam Health Care Campus; Technion Israel Institute of Technology; Rappaport Faculty of Medicine; Ben-Gurion University of the Negev
RP Sharon, H (corresponding author), Tel Aviv Sourasky Med Ctr, Inst Pain Med, Dept Anesthesia & Crit Care Med, 6 Weitzman St, IL-64239 Tel Aviv, Israel.
EM haggais@tasmc.gov.il
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NR 38
TC 27
Z9 33
U1 0
U2 13
PU DOVE MEDICAL PRESS LTD
PI ALBANY
PA PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND
SN 1178-7090
EI 
J9 J PAIN RES
JI J. Pain Res.
PD JUN 15
PY 2018
VL 11
IS 
BP 1411
EP 1419
DI 10.2147/JPR.S159852
PG 9
WC Clinical Neurology
SC Neurosciences & Neurology
GA GO8BQ
UT WOS:000440308500003
PM 30104896
DA 2026-01-16
ER

PT J
AU Schuster, L
AF Schuster, Lynn
TI Integrative Medicine in the Oncology Setting, What Does the Research Show?
SO JNP-JOURNAL FOR NURSE PRACTITIONERS
LA English
DT Article
DE acupuncture; cancer; cancer prevention; complementary; complementary alternative medicine; integrative; integrative oncology; massage; meditation; supplements; yoga
ID breast-cancer; interventions; massage; chemotherapy; acupuncture; pain
AB Most oncology patients are using some form of complementary alternative medicine (CAM). These can include acupuncture, massage, yoga, homeopathy, energy work, spiritual healers, vitamins and supplements, mind-body interventions, diets, and many other modalities. Although many of these interventions are safe and beneficial, some of them can be harmful. Unfortunately, because of time constraints, knowledge deficits, and the acuity of our patients, assessment of the use of CAM is often overlooked. As nurse practitioners, we must educate ourselves about the evidence for safety and efficacy of these interventions.
C1 [Schuster, Lynn] Univ Arizona, Integrat Med, Tucson, AZ 85721 USA.
C3 University of Arizona
RP Schuster, L (corresponding author), Univ Arizona, Integrat Med, Tucson, AZ 85721 USA.
EM Lynn.schuster2@bannerhealth.com
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NR 19
TC 1
Z9 1
U1 0
U2 14
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1555-4155
EI 1878-058X
J9 JNP-J NURSE PRACT
JI JNP-J. Nurse Pract.
PD APR 15
PY 2018
VL 14
IS 4
BP 276
EP 282
DI 10.1016/j.nurpra.2017.11.015
PG 7
WC Nursing
SC Nursing
GA GC8QS
UT WOS:000430061700018
DA 2026-01-16
ER

PT J
AU Zeng, YJ
   Lin, YH
   Wang, YC
   Chang, JH
   Wu, JH
   Hsu, SF
   Tsai, SY
   Lin, CH
   Wen, YR
AF Zeng, Yen-Jing
   Lin, Yu-Hsiang
   Wang, You-Cheng
   Chang, Ju-Hsin
   Wu, Jih-Huah
   Hsu, Sheng-Feng
   Tsai, Shih-Ying
   Lin, Ching-Huang
   Wen, Yeong-Ray
TI Laser acupuncture-induced analgesic effect and molecular alterations in an incision pain model: a comparison with electroacupuncture-induced effects
SO LASERS IN MEDICAL SCIENCE
LA English
DT Article
DE Laser acupuncture; Postoperative pain; MAPK; iNOS; TNF
ID postoperative pain; thermal hyperalgesia; management; microglia; kinase; injury; rats
AB Low-level laser acupuncture (LLLA) produces photobiomodulation through acupuncture point and is an alternative to low-level laser therapy. Although the analgesic effect of LLLA on chronic pain has been proven, its effect on acute postincisional pain has yet to be investigated. A plantar incision (PI) model was used to mimic human postsurgical pain. Male adult rats received GaAlAs laser irradiation at the right ST36 acupoint immediately after operation and on the following 4 days. Three laser treatment groups (two red laser groups with a 30- or 15-min treatment duration and one 30-min near-infrared laser group) were compared with sham LLLA and naive groups and an electroacupuncture (EA) group (separate study). Behavioral withdrawal thresholds of both hind paws were measured before and after incision. Expression of mitogen-activated protein kinases (p-ERK and p-p38), inducible nitric oxide synthase (iNOS), and tumor necrosis factor (TNF) in the spinal cord was analyzed. All three LLLA treatments attenuated post-PI tactile allodynia in the ipsilateral paw, but only the 30-min red laser treatment affected the contralateral paw and had similar efficacy to that of EA. All laser treatments barely reduced heat hyperalgesia in both hind paws. At 3 days after PI, the 30-min red laser group showed reversed increases of PI-induced p-ERK, p-p38, and iNOS but not TNF expression in the spinal cord. Repetitive LLLA treatments ameliorated PI-induced mechanical pain. The inhibition of multiple sensitization signals highlights the unique clinical role of LLLA. Thus, LLLA is an alternative to EA as an adjuvant for postoperative pain control.
C1 [Zeng, Yen-Jing; Chang, Ju-Hsin] China Med Univ, Coll Med, Grad Inst Clin Med, Taichung, Taiwan.
   [Lin, Yu-Hsiang; Lin, Ching-Huang] Natl Yunlin Univ Sci & Technol, Microelect & Optoelect Engn Dept Elect Engn, Touliu, Yunlin, Taiwan.
   [Wang, You-Cheng; Lin, Ching-Huang] Natl Yunlin Univ Sci & Technol, Dept Elect Engn, Touliu, Yunlin, Taiwan.
   [Chang, Ju-Hsin; Tsai, Shih-Ying; Wen, Yeong-Ray] China Med Univ Hosp, Dept Anesthesiol, 2 Yuh Der Rd, Taichung 40447, Taiwan.
   [Wu, Jih-Huah] Ming Chuan Univ, Dept Biomed Engn, Taipei, Taiwan.
   [Hsu, Sheng-Feng; Wen, Yeong-Ray] China Med Univ, Coll Chinese Med, Grad Inst Acupuncture Sci, Taichung, Taiwan.
   [Hsu, Sheng-Feng] China Med Univ Hosp, Taipei Branch, Dept Acupuncture, Taipei, Taiwan.
   [Hsu, Sheng-Feng; Wen, Yeong-Ray] China Med Univ, Acupuncture Res Ctr, Taichung, Taiwan.
   [Wen, Yeong-Ray] China Med Univ, Sch Med, Dept Anesthesiol, Taichung, Taiwan.
   [Wen, Yeong-Ray] China Med Univ, Sch Med, Dept Anesthesiol, Ctr Pain Res & Management, Taichung, Taiwan.
C3 China Medical University Taiwan; National Yunlin University Science & Technology; National Yunlin University Science & Technology; China Medical University Taiwan; China Medical University Hospital - Taiwan; Ming Chuan University; China Medical University Taiwan; China Medical University Taiwan; China Medical University Hospital - Taiwan; China Medical University Taiwan; China Medical University Taiwan; China Medical University Taiwan
RP Wen, YR (corresponding author), China Med Univ Hosp, Dept Anesthesiol, 2 Yuh Der Rd, Taichung 40447, Taiwan.; Wen, YR (corresponding author), China Med Univ, Coll Chinese Med, Grad Inst Acupuncture Sci, Taichung, Taiwan.; Wen, YR (corresponding author), China Med Univ, Acupuncture Res Ctr, Taichung, Taiwan.; Wen, YR (corresponding author), China Med Univ, Sch Med, Dept Anesthesiol, Taichung, Taiwan.; Wen, YR (corresponding author), China Med Univ, Sch Med, Dept Anesthesiol, Ctr Pain Res & Management, Taichung, Taiwan.
EM yr.wen@yahoo.com.tw
FU National Science Council in Taiwan [NSC101-2314-B-039-005-MY3]; Taiwan Ministry of Health and Welfare Clinical Trial Center [MOHW106-TDU-B-212-113004]; China Medical University Hospital [DMR-106-217, DMR-106-181];  [MOST 104-2314-B-039-020-MY2];  [MOST 105-2320-B-039-029]
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NR 44
TC 27
Z9 29
U1 2
U2 18
PU SPRINGER LONDON LTD
PI LONDON
PA 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND
SN 0268-8921
EI 1435-604X
J9 LASER MED SCI
JI Lasers Med. Sci.
PD FEB 15
PY 2018
VL 33
IS 2
BP 295
EP 304
DI 10.1007/s10103-017-2367-7
PG 10
WC Engineering, Biomedical; Surgery
SC Engineering; Surgery
GA FV3HO
UT WOS:000424458900010
PM 29103083
DA 2026-01-16
ER

PT J
AU Birch, S
   Lee, MS
   Alraek, T
   Kim, TH
AF Birch, Stephen
   Lee, Myeong Soo
   Alraek, Terje
   Kim, Tae-Hun
TI Overview of Treatment Guidelines and Clinical Practical Guidelines That Recommend the Use of Acupuncture: A Bibliometric Analysis
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Review
DE clinical practice guideline; treatment guideline; acupuncture; systematic review; recommendation; snowballing method
ID traditional chinese medicine; posttraumatic-stress-disorder; randomized controlled-trials; irritable-bowel-syndrome; individual-patient-data; in-vitro fertilization; cancer-related fatigue; quality-of-life; low-back-pain; alternative medicine
AB Introduction: As positive evidence emerges for the use of an intervention to treat a health problem, the intervention gradually becomes incorporated into treatment guidelines (TGs) or clinical practice guidelines (CPGs) that are related to that health problem. To assess whether this general hypothesis can apply to acupuncture, 96 health problems were identified for which positive conclusions in systematic reviews and meta-analyses regarding the effectiveness of acupuncture have been made and then searched for TGs or CPGs that have recommended the use of acupuncture. Methods: Through August 31, 2017, searches were performed in relevant medical databases and Google using treatment guideline, clinical practice guideline, and the names of the 96 medical conditions as search terms. A snow-balling search approach was adopted. All positive recommendations were added into the registry. Results: A total of 1311 publications were found that recommended using acupuncture published between 1991 and 2017. The number per year reached 50 in 2005 and 100 in 2009. In addition, 2189 positive recommendations were found for the use of acupuncture. Of these, 1486 were related to 107 pain indications and 703 were related to 97 nonpain indications. These recommendations were made by a wide range of groups, such as government health institutions, national guideline, and medical specialty groups. The recommendations came from around the world but were especially abundant in North America, Europe, and Australasia. Discussion and conclusion: Considerably more recommendations were found for the use of acupuncture than are known within the acupuncture or medical communities. A trend by year was also found; a rise in the number of positive statements about acupuncture was typically followed by a rise in the number of recommendations of acupuncture. Thus, the recommendations followed the emergent evidence for acupuncture. Better implementation plans need to be developed for the CPG/TG recommendations about acupuncture to be more effective/efficient.
C1 [Birch, Stephen; Alraek, Terje] Kristiania Univ Coll, Dept Hlth Sci, N-0107 Oslo, Norway.
   [Lee, Myeong Soo] Korea Inst Oriental Med, Clin Med Div, Daejeon, South Korea.
   [Alraek, Terje] UiT Arctic Univ Norway, Dept Community Med, Natl Res Ctr Complementary & Alternat Med, Fac Med, Tromso, Norway.
   [Kim, Tae-Hun] Kyung Hee Univ, Korean Med Hosp, Korean Med Clin Trial Ctr, Seoul, South Korea.
C3 Kristiania University College; Korea Institute of Oriental Medicine (KIOM); UiT The Arctic University of Tromso; Kyung Hee University; Kyung Hee University Hospital
RP Birch, S (corresponding author), Kristiania Univ Coll, Dept Hlth Sci, N-0107 Oslo, Norway.
EM sjbirch@gmail.com
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NR 306
TC 60
Z9 75
U1 1
U2 40
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD AUG 15
PY 2018
VL 24
IS 8
BP 752
EP 769
DI 10.1089/acm.2018.0092
EA JUN 2018
PG 18
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GQ7KY
UT WOS:000435549600001
PM 29912569
DA 2026-01-16
ER

PT J
AU Meng, FF
   Feng, YH
AF Meng, Fan-Feng
   Feng, Yan-Hong
TI A pilot study of acupuncture at pain acupoints for cervical cancer pain.
SO Medicine
LA English
DT Journal Article
AB This retrospective study aimed to investigate the feasible effectiveness of  acupuncture at pain acupoints for the treatment of patients with cervical cancer  pain (CCP). A total of 64 cases were analyzed. All these cases were assigned to  an acupuncture group or a control group according to the different therapies they  received. The cases in the acupuncture group received acupuncture treatment at  pain acupoints, while the subjects in the control group underwent acupuncture at  regular acupoints. The primary endpoint was CCP, assessed by numeric rating scale  (NRS). The secondary endpoints were evaluated by the European Organization for  Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC  QLQ-C30), and Karnofsky Performance Status (KPS). In addition, adverse events  were also recorded during the treatment period. After treatment, patients in the  acupuncture group exerted greater outcomes in CCP reduction when compared with  patients in the control group (P < .01). In addition, no adverse events were  recorded in either group. The results of this study showed that acupuncture at  pain acupoints might be efficacious in patients with CCP after 14-day treatment.
C1 Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.
NR 0
TC 0
SN 1536-596
EI 0025-797
J9 Medicine (Baltimore)
PD DEC 30
PY 2018
VL 97
IS 52
BP e13736
EP e13736
DI 10.1097/MD.0000000000013736
PG 1
WC Acupuncture Points; Acupuncture Therapy; methods; Cancer Pain; etiology; Feasibility Studies; Female; Humans; Karnofsky Performance Status; Middle Aged; Pilot Projects; Quality of Life; Retrospective Studies; Surveys and Questionnaires; Treatment Outcome; Uterine Cervical Neoplasms; complications
UT PubMed:30593148
PM 30593148
DA 2018-12-30
ER

PT J
AU Kim, TH
   Kang, JW
   Lee, TH
AF Kim, Tae-Hun
   Kang, Jung Won
   Lee, Tae Hee
TI Therapeutic options for aromatase inhibitor-associated arthralgia in breast
SO Maturitas
LA English
DT Journal Article
DE Acupuncture; Aromatase inhibitor-associated arthralgia; Network meta-analysis; Overview of systematic reviews; Scoping study
AB Aromatase inhibitor-associated arthralgia (AIA) is a common problem in breast  cancer survivors and is associated with noncompliance with aromatase inhibitor  therapy. The aim of this research was to assess the current evidence for the  various therapeutic options available for AIA. We searched the PubMed, EMBASE,  Cochrane Database of Systematic Reviews, and Database of Abstracts of Reviews of  Effects for systematic reviews of trials investigating treatments for AIA to June  2018. Eligible systematic reviews were subjected to evidence mapping and the  randomized controlled trials included in the systematic reviews were  hand-searched for a network meta-analysis. Six systematic reviews were included  in the evidence mapping. Acupuncture was the most common treatment modality  studied (four randomized controlled trials), and pharmacological interventions,  aerobic exercise, Nordic walking, omega-3 fatty acids, and vitamin D were  assessed less frequently. In view of the limitations in the overall confidence  level for each review, the evidence for acupuncture as an effective treatment for  AIA was considered low. Second, data from 6 randomized controlled trials were  included in the network meta-analysis. When compared with a waiting list control,  acupuncture (mean difference [MD] -2.00, 95% confidence interval [CI] -3.16,  -0.84), aerobic exercise (MD -0.80, 95% CI -1.33, -0.016), and omega-3 fatty  acids (MD -2.10, 95% CI -3.23, -0.97) significantly improved pain severity  scores. Network meta-analysis of adverse events was not possible because of poor  reporting. Acupuncture is presently the most widely investigated intervention but  is recommended for AIA with low overall confidence based on the current evidence.
C1 Korean Medicine Clinical Trial Center, Korean Medicine Hospital, Kyung Hee University, (#)23 kyungheedae-ro, Dondaemun-gu, Seoul, 130-872, South Korea.
   Department of Acupuncture & Moxibustion, College of Korean Medicine, Kyung Hee University, (#)23 kyungheedae-ro, Dondaemun-gu, Seoul, 130-872, South Korea.
   Department of Formulae Pharmacology, College of Korean Medicine, Gachon University, Seong-Nam, South Korea.
EM taehunkim@khu.ac.kr
NR 0
TC 0
SN 1873-411
EI 
J9 Maturitas
PD NOV 13
PY 2018
VL 118
IS 
BP 29
EP 37
DI 10.1016/j.maturitas.2018.09.005
PG 8
WC Acupuncture Therapy; Aromatase Inhibitors; adverse effects; Arthralgia; chemically induced; Breast Neoplasms; drug therapy; Cancer Survivors; Evidence-Based Medicine; Exercise; Fatty Acids, Omega-3; therapeutic use; Female; Humans; Pain Measurement; Review Literature as Topic; Vitamin D; therapeutic use
UT PubMed:30415752
PM 30415752
DA 2018-11-13
ER

PT J
AU Anshasi, HA
   Ahmad, M
AF Anshasi, Huda A
   Ahmad, Muayyad
TI An assessment of methodological quality of systematic reviews of acupuncture and
SO Complementary therapies in clinical practice
LA English
DT Journal Article
DE A systematic literature review; Acupuncture; Cancer-related pain; Meta-analyses; Patients with cancer
AB BACKGROUND AND PURPOSE: There currently exist many systematic reviews aimed at  assessing acupuncture and related therapy effectiveness in cancer-related pain  management. However, the methodological quality of existing systematic reviews  remains unclear. The purpose of this review was to summarize and evaluate the  methodological quality of these systematic reviews and meta-analyses papers.  METHODS: A comprehensive search on multiple databases was performed using  Assessing the Methodological Quality of Systematic Reviews (AMSTAR). RESULTS:  Fourteen systematic reviews published between 2005 and 2017 were eligible for  inclusion. The consensus across the included reviews was that acupuncture and  related therapies alone did not have superior pain-relieving effects as compared  with analgesic administration using various validated pain scales. However, as  compared with analgesic administration alone, acupuncture and related therapies  plus analgesics resulted in reduced cancer related-pain. CONCLUSION: The study  findings emphasized that acupuncture and related therapies alone did not have  clinically significant effects at cancer-related pain reduction as compared with  analgesic administration alone. Clinicians may consider acupuncture and related  therapies as adjunctive therapies for cancer-related pain management, in  particular, when pain control is unsatisfactory under analgesics alone.  Furthermore, the researchers should conduct the SRs and meta-analyses according  to the AMSTAR and PRISMA.
C1 The University of Jordan, School of Nursing, Amman, Jordan. 
   The University of Jordan, School of Nursing, Amman, Jordan.
EM mma4jo@yahoo.com
NR 0
TC 0
SN 1873-694
EI 
J9 Complement Ther Clin Pract
PD JUL 31
PY 2018
VL 32
IS 
BP 163
EP 168
DI 10.1016/j.ctcp.2018.06.013
PG 5
WC Acupuncture Therapy; Cancer Pain; therapy; Humans
UT PubMed:30057045
PM 30057045
DA 2018-07-31
ER

PT J
AU Dogan, MD
AF Dogan, Melike Demir
TI The effect of reiki on pain: A meta-analysis
SO COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
LA English
DT Article
DE Reiki; Meta-analysis; Pain
ID nursing intervention; therapy; anxiety; cancer; management; trial; acupuncture; adults
AB Objective: Pain is one of the most common symptoms and may lead to important psychological, mental, and physiological problems in individuals. According to data by The Center for Reiki Research, Reiki is an effective approach to decrease the levels of pain, depression, and anxiety. Therefore, the aim of this meta-analysis was to investigate the effect of Reiki on pain level. Methods: Randomized controlled clinical trials in databases of Pubmed, ISI Web of Sciences, and Google Scholar were investigated. 4 randomized controlled studies involving 212 participants were included in the meta-analysis. Results: The result obtained after the final Reiki application was evaluated in VAS pain score. When Reiki (n = 104) group was compared with control group (n = 108), standardized mean difference was observed to be -0.927 (95% CI: -1.867 to 0.0124). Reiki was observed to cause a statistically significant decrease in VAS score. Conclusion: Consequently, this meta-analysis revealed that Reiki was an effective approach in relieving the pain. (C) 2018 Elsevier Ltd. All rights reserved.
C1 [Dogan, Melike Demir] Gumushane Univ, Fac Hlth Sci, Baglarbasi Mahallesi, TR-29100 Gumushane, Turkey.
C3 Gumushane University
RP Dogan, MD (corresponding author), Gumushane Univ, Fac Hlth Sci, Baglarbasi Mahallesi, TR-29100 Gumushane, Turkey.
EM melekdm@gmail.com
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NR 26
TC 52
Z9 66
U1 1
U2 62
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1744-3881
EI 1873-6947
J9 COMPLEMENT THER CLIN
JI Complement. Ther. Clin. Pract.
PD MAY 15
PY 2018
VL 31
IS 
BP 384
EP 387
DI 10.1016/j.ctcp.2018.02.020
PG 4
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GG2KG
UT WOS:000432520800061
PM 29551623
DA 2026-01-16
ER

PT J
AU Browne, N
   Bush, P
   Cabo, F
AF Browne, Neil
   Bush, Philippa
   Cabo, Fernando
TI Relieving pressure - An evaluation of Shiatsu treatments for cancer & palliative care patients in an NHS setting
SO EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
LA English
DT Article
DE Shiatsu; Bodywork; Cancer; MYCaW; NHS; Palliative care
ID well-being mycaw; complementary therapy; support care; integrative oncology; yourself concerns; acupressure; medicine; pain; questionnaire; experiences
AB Introduction: The study investigated the effectiveness of Shiatsu therapy in relation to the management of health and wellbeing concerns of cancer and palliative care patients in an out-patient clinic. Method: Patients are referred to the Complementary Therapies Service for symptom management, particularly stress and anxiety, but also other symptoms such as nausea or insomnia. Data was collected following use of the Measure Yourself Concerns and Wellbeing (MYCaW) questionnaire, which was designed for evaluating supportive care interventions. Results: Mean changes in post-intervention MYCaW scores were highly significant (p < 0.001), demonstrating considerable improvements in both presenting symptoms and perceptions of wellbeing. Based on a significance level of 0.05, both the Wilcoxon signed-ranks test and the two-tailed t-test indicated that post-treatment ranks and means were statistically significantly lower than pre-treatment ranks and means in the categories. Conclusion: Anxiety, stress management and pain scores were the most improved. Wellbeing scores also improved, on average, by two points on the Likert scale. Patients stated that 'being listened to' and 'being heard' were important factors when describing how Shiatsu had helped. We suggest that a study using larger numbers is necessary in order to provide more robust evidence rather than emerging trends.
C1 [Browne, Neil; Bush, Philippa; Cabo, Fernando] Whipps Cross Univ Hosp, Margaret Ctr, Barts Hlth NHS Trust, London E11 1NR, England.
C3 Barts Health NHS Trust; Whipps Cross University Hospital
RP Browne, N (corresponding author), Whipps Cross Univ Hosp, Margaret Ctr, Barts Hlth NHS Trust, London E11 1NR, England.
EM neil.browne@bartshealth.nhs.uk; Fernando.Cabo@marywardcentre.ac.uk
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NR 47
TC 3
Z9 3
U1 0
U2 14
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1876-3820
EI 1876-3839
J9 EUR J INTEGR MED
JI Eur. J. Integr. Med.
PD AUG 15
PY 2018
VL 21
IS 
BP 27
EP 33
DI 10.1016/j.eujim.2018.06.002
PG 7
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GS5UR
UT WOS:000443737400005
DA 2026-01-16
ER

PT J
AU Lam, WL
   Yeung, WF
   Wong, MK
   Cheung, CW
   Chan, KKL
   Ngan, HYS
   Wong, CKH
   Chen, HY
   Lao, L
AF Lam, Wing Lok
   Yeung, Wing Fai
   Wong, Mei Kuen
   Cheung, Chi Wai
   Chan, Karen Kar Loen
   Ngan, Hextan Yuen Sheung
   Wong, Carlos King Ho
   Chen, Hai Yong
   Lao, Lixing
TI Combined electroacupuncture and auricular acupuncture for postoperative pain
SO Trials
LA English
DT Journal Article
DE AUC; Acupuncture; Analgesia; Health economic analysis; Morphine consumption; Operation; Placebo; RCT
AB BACKGROUND: Postoperative pain is a major complaint following abdominal surgery  for gynecological diseases. Effective postoperative pain control after abdominal  surgery is particularly important for patient recovery, mobility, and  satisfaction. Acupuncture has been commonly used for pain management. However,  its efficacy in postoperative pain control is inconclusive and health economic  evaluation is limited. METHODS: A randomized, sham-controlled, patient- and-  assessor-blind trial is designed to evaluate the efficacy and safety of  acupuncture in managing postoperative pain following abdominal surgery of  gynecological diseases. Patients who are eligible for laparotomy with a midline  incision for gynecological neoplasia, including ovarian mass, uterine mass, and  cervical lesions, will be recruited. Seventy-two participants will be randomly  allocated to an acupuncture or non-invasive sham control in a 1:1 ratio.  Treatment will be done within 2 h before operation, upon arrival to the ward and  once daily for 5 days. The Pain Numerical Rating Scale (NRS) on the first 5 days  during hospitalization will be the primary outcome and will be analyzed using the  area-under-the-curve (AUC) method. The secondary outcome measures include  frequency of rescue analgesic use during hospital stay, cumulative morphine  consumption; quality of recovery as measured by time to recovery variables and  the Quality of Recovery-9 (QoR-9); quality of life as measured by the Short  Form-6 dimension (SF-6D) and EuroQol-5 Dimension-5 Level (EQ-5D-5 L). The  incremental cost-effectiveness ratio of acupuncture vs sham acupuncture will be  calculated. DISCUSSION: This study protocol provides an example of integrative  medicine practice in a hospital setting for the management of postoperative pain  using acupuncture treatment. The acupuncture treatment protocol, if proven to be  effective, can be implemented in routine settings to play a role in postoperative  pain management for patients who have undergone abdominal surgery for  gynecological diseases. TRIAL REGISTRATION: ClinicalTrials.gov, ID: NCT02851186 .  Registered on 19 July 2016.
C1 School of Chinese Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, Special Administrative Region of China.
   School of Nursing, the Hong Kong Polytechnic University, Kowloon, Hong Kong, Special Administrative Region of China.
   School of Chinese Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, Special Administrative Region of China.
   Department of Anesthesiology, The University of Hong Kong, 4/F, K Block, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong, Special AdministrativeRegion of China.
   Department of Obstetrics and Gynecology, The University of Hong Kong, 6/F, Professorial Block, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong,Special Administrative Region of China.
   Department of Obstetrics and Gynecology, The University of Hong Kong, 6/F, Professorial Block, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong,Special Administrative Region of China.
   Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F, Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Pokfulam, Hong Kong, SpecialAdministrative Region of China.
   School of Chinese Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, Special Administrative Region of China.
   School of Chinese Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, Special Administrative Region of China. lxlao1@hku.hk.
NR 0
TC 0
SN 1745-621
EI 
J9 Trials
PD JAN 6
PY 2018
VL 19
IS 1
BP 8
EP 8
DI 10.1186/s13063-017-2359-8
PG 0
WC Abdomen; surgery; Acupuncture, Ear; adverse effects; Analgesics; therapeutic use; Double-Blind Method; Electroacupuncture; adverse effects; Female; Genital Diseases, Female; surgery; Gynecologic Surgical Procedures; adverse effects; Hong Kong; Humans; Pain Measurement; Pain, Postoperative; diagnosis; Quality of Life; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome
UT PubMed:29301556
PM 29301556
DA 2018-01-06
ER

PT J
AU Litscher, G
AF Litscher, Gerhard
TI Introduction to the Medicines Special Issue on Acupuncture-Basic Research and
SO Medicines (Basel, Switzerland)
LA English
DT Editorial
DE acupuncture; depression; low back pain (LBP); moxibustion; myopia; osteoarthritis; post-stroke; pulse diagnosis; sciatica; uterine cancer
AB This Medicines special issue focuses on the further investigation, development,  and modernization of acupuncture in basic research settings, as well as in  clinical applications. The special issue contains 12 articles reporting latest  evidence-based results of acupuncture research, and exploring acupuncture in  general. Altogether 44 authors from all over the world contributed to this  special issue.
C1 Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and TCMResearch Center Graz, Medical University of Graz, Auenbruggerplatz 39, EG19, 8036Graz, Austria. gerhard.litscher@medunigraz.at.
NR 0
TC 0
SN 2305-632
EI 2305-632
J9 Medicines (Basel)
PD SEP 6
PY 2018
VL 5
IS 3
BP 
EP 
DI 10.3390/medicines5030099
PG 0
UT PubMed:30181449
PM 30181449
DA 2018-09-06
ER

PT J
AU Bao, T
   Seidman, AD
   Piulson, L
   Vertosick, E
   Chen, X
   Vickers, AJ
   Blinder, VS
   Zhi, WQI
   Li, Q
   Vahdat, LT
   Dickler, MN
   Robson, ME
   Mao, JJ
AF Bao, Ting
   Seidman, Andrew D.
   Piulson, Lauren
   Vertosick, Emily
   Chen, Xi
   Vickers, Andrew J.
   Blinder, Victoria S.
   Zhi, Wanqing I.
   Li, Qing
   Vahdat, Linda T.
   Dickler, Maura N.
   Robson, Mark E.
   Mao, Jun J.
TI A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients
SO EUROPEAN JOURNAL OF CANCER
LA English
DT Article
DE Breast cancer; Acupuncture; Chemotherapy-induced peripheral neuropathy; CIPN; Paclitaxel; Chemotherapy
ID small fiber neuropathy; pain; electroacupuncture; prevention
AB Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is a common and potentially dose-limiting side-effect of neurotoxic chemotherapy for cancer patients. We evaluated the preliminary efficacy of acupuncture in preventing worsening CIPN in patients receiving paclitaxel. Methods: In this phase IIA single-arm clinical trial, we screened stage I-III breast cancer patients receiving neoadjuvant/adjuvant weekly paclitaxel for development of CIPN. The primary objective was to assess acupuncture's efficacy in preventing the escalation of National Cancer Institute-Common Toxicity Criteria for Adverse Events (NCI-CTCAE), version 4.0, grade II CIPN to higher grades. Acupuncture was deemed worthy of further study if 23 or more of the 27 enrolled patients did not develop grade III CIPN. Outcome measures (NCI-CTCAE CIPN grade, Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity [FACT/GOG-Ntx], Neuropathic Pain Scale [NPS]) were obtained weekly during the intervention. Results: Of 104 patients screened, 37 developed grade II CIPN (36%), and 28 (27%) enrolled into the intervention phase; one was removed due to protocol violation. Of the 27 patients receiving acupuncture, 26 completed paclitaxel treatment without developing grade III CIPN, meeting our prespecified success criteria for declaring acupuncture worthy of further study. FACT/GOG-Ntx and NPS scores remained stable during the intervention while continuing weekly paclitaxel. Acupuncture treatment was well tolerated; 4 of 27 (15%) patients reported grade I bruising. Conclusions: Acupuncture was safe and showed preliminary evidence of effectiveness in reducing the incidence of high grade CIPN during chemotherapy. A follow-up randomised controlled trial is needed to establish definitive efficacy in CIPN prevention for patients at risk. (C) 2018 Elsevier Ltd. All rights reserved.
C1 [Bao, Ting; Piulson, Lauren; Li, Qing; Mao, Jun J.] Mem Sloan Kettering Canc Ctr, 1429 First Ave, New York, NY 10021 USA.
   [Seidman, Andrew D.; Vahdat, Linda T.; Dickler, Maura N.; Robson, Mark E.] Mem Sloan Kettering Canc Ctr, 300 East 66th St, New York, NY 10065 USA.
   [Vertosick, Emily; Vickers, Andrew J.; Blinder, Victoria S.] Mem Sloan Kettering Canc Ctr, 485 Lexington Ave, New York, NY 10017 USA.
   [Chen, Xi] Mem Sloan Kettering Canc Ctr, 444 E 68th St, New York, NY 10065 USA.
   [Zhi, Wanqing I.] Mem Sloan Kettering Canc Ctr Commack, 650 Commack Rd, Commack, NY 11725 USA.
C3 Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center
RP Bao, T (corresponding author), Bendheim Integrat Med Ctr, 1429 First Ave, New York, NY 10021 USA.
EM baot@mskcc.org; seidmana@mskcc.org; piulsonl@mskcc.org; vertosie@mskcc.org; chenx2@mskcc.org; vickersa@mskcc.org; blinderv@mskcc.org; zhiw@mskcc.org; liq2@mskcc.org; vahdatl@mskcc.org; dicklerm@mskcc.org; robsonm@mskcc.org; maoj@mskcc.org
FU National Cancer Institute [R21CA173263, R01CA158243]; Memorial Sloan Kettering Cancer Center P30 grant [P30-CA008748]; Byrne Fund at Memorial Sloan Kettering Cancer Center; Translational Research and Integrative Medicine Fund at Memorial Sloan Kettering Cancer Center; National Cancer Institute [P30CA008748] Funding Source: NIH RePORTER
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NR 33
TC 82
Z9 97
U1 2
U2 53
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0959-8049
EI 1879-0852
J9 EUR J CANCER
JI Eur. J. Cancer
PD SEP 15
PY 2018
VL 101
IS 
BP 12
EP 19
DI 10.1016/j.ejca.2018.06.008
PG 8
WC Oncology
SC Oncology
GA GQ7BP
UT WOS:000441888700002
PM 30007894
DA 2026-01-16
ER

PT J
AU Aderibigbe, O
   Groft-MacFarlane, C
   Chu, EY
AF Aderibigbe, Oyinade
   Groft-MacFarlane, Caroline
   Chu, Emily Y
TI A Blue-Gray Macule on the Back: Challenge.
SO The American Journal of dermatopathology
LA English
DT Journal Article
C1 Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA
   and.
   Dermatology Associates of Bryn Mawr Medical Specialists, Bryn Mawr, PA.
   Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA
   and.
NR 0
TC 0
SN 1533-031
EI 
J9 Am J Dermatopathol
PD OCT 12
PY 2018
VL 42
IS 1
BP e4
EP e4
DI 10.1097/DAD.0000000000001268
PG 1
WC Acupuncture Therapy; methods; Biopsy, Needle; Chronic Pain; therapy; Diagnosis, Differential; Follow-Up Studies; Humans; Immunohistochemistry; Low Back Pain; diagnosis; Male; Middle Aged; Nevus, Blue; diagnosis; Ochronosis; diagnosis; Pigmentation Disorders; diagnosis; Rare Diseases
UT PubMed:30308544
PM 30308544
DA 2018-10-12
ER

PT J
AU Pan, Y
   Yang, K
   Shi, X
   Liang, H
   Shen, X
   Wang, R
   Ma, L
   Cui, Q
   Yu, R
   Dong, Y
AF Pan, Yuanqing
   Yang, Kehu
   Shi, Xiue
   Liang, Haiqian
   Shen, Xiping
   Wang, Renjie
   Ma, Li
   Cui, Qi
   Yu, Runze
   Dong, Yi
TI Clinical Benefits of Acupuncture for the Reduction of Hormone Therapy-Related
SO Integrative cancer therapies
LA English
DT Journal Article
DE acupuncture; breast cancer; hormone therapy–related side effects; quality of life; systematic review
AB IMPORTANCE: Acupuncture can help reduce unpleasant side effects associated with  endocrine therapy for breast cancer. Nevertheless, comprehensive evaluation of  current evidence from randomized controlled trials(RCTs) is lacking. OBJECTIVE:  To estimate the efficacy of acupuncture for the reduction of hormone  therapy-related side effects in breast cancer patients. EVIDENCE REVIEW: RCTs of  acupuncture in breast cancer patients that examined reductions in hormone  therapy-related side effects were retrieved from PubMed, EMBASE, Web of Science,  Ovid MEDLINE, and Cochrane Library databases through April 2016. The quality of  the included studies was evaluated according to the 5.2 Cochrane Handbook  standards, and CONSORT and STRICTA (Revised Standards for Reporting Interventions  in Clinical Trials of Acupuncture) statements. INTERVENTION: Interventions  included conventional acupuncture treatment compared with no treatment, placebo,  or conventional pharmaceutical medication. Major outcome measures were the  alleviation of frequency and symptoms and the presence of hormone therapy-related  side effects. Findings/Results. A total of 17 RCTs, including a total of 810  breast cancer patients were examined. The methodological quality of the trials  was relatively rigorous in terms of randomization, blinding, and sources of bias.  Compared with control therapies, the pooled results suggested that acupuncture  had moderate effects in improving stiffness. No significant differences were  observed in hot flashes, fatigue, pain, gastrointestinal symptoms, Kupperman  index, general well-being, physical well-being, tumor necrosis factor (TNF), and  interleukin (IL). CONCLUSIONS: Acupuncture therapy appears to be potentially  useful in relieving functional stiffness. However, further large-sample trials  with evidence-based design are still needed to confirm these findings.
C1 1 Tianjin Medical College, Tianjin, China.
   2 Lanzhou University, Lanzhou, Gansu, China.
   2 Lanzhou University, Lanzhou, Gansu, China.
   3 Gansu Rehabilitation Center Hospital, Lanzhou, China.
   4 Tianjin Pingjin Hospital, Tianjin, China.
   2 Lanzhou University, Lanzhou, Gansu, China.
   4 Tianjin Pingjin Hospital, Tianjin, China.
   5 General Hospital of Tianjin Medical University, Tianjin, China.
   6 The First Affiliated Hospital of Lanzhou University, Lanzhou, Gansu, China.
   1 Tianjin Medical College, Tianjin, China.
   1 Tianjin Medical College, Tianjin, China.
NR 0
TC 0
SN 1552-695
EI 1534-735
J9 Integr Cancer Ther
PD AUG 18
PY 2018
VL 17
IS 3
BP 602
EP 618
DI 10.1177/1534735418786801
PG 16
WC Acupuncture; methods; Animals; Breast Neoplasms; drug therapy; Clinical Trials as Topic; Female; Hormone Replacement Therapy; adverse effects; Humans
UT PubMed:30117343
PM 30117343
DA 2018-08-18
ER

PT J
AU Su, CF
AF Su, Ching-Feng
TI Home care with acupuncture increased the quality of life in a patient with
SO Journal of integrative medicine
LA English
DT Journal Article
DE Acupuncture; Cancer; Case report; Hospice care; Neuropathic pain; Palliative care; Quality of life
AB A 66-year-old female patient was diagnosed with hepatocellular carcinoma  accompanied by neuropathic pain induced by a metastatic tumor that compromised  root and spinal canal. Although her pain was relieved following medical  treatment, breakthrough pain occurring 1-2 times a day was still distressing.  Neuropathic pain in her right lower limb caused discomfort and irritability and  decreased her quality of life. We had limited options to adjust her prescription  drug regime, due to the side effect of these drugs. Although acupuncture therapy  was only performed at her home once a week, the efficacy was outstanding. The  patient did not report any further instances of breakthrough pain, and she did  not require additional bolus morphine. She could comfortably live in her familiar  surroundings with her family and did not require any emergency room visits or  admission into the hospital during the last month of her life. She had excellent  quality of life in the terminal period of her life, and could even participate in  a family function during this time. The present case report suggests that  acupuncture may have a role in treating neuropathic pain induced by bone  metastasis in patients with advanced cancer across clinical and in-home settings.
C1 Department of Family Medicine, Pingtung Christian Hospital, Pingtung County 900, Taiwan, China.
EM 04836@ptch.org.tw
NR 0
TC 0
SN 
EI 2095-496
J9 J Integr Med
PD APR 25
PY 2018
VL 16
IS 3
BP 208
EP 210
DI 10.1016/j.joim.2018.04.003
PG 2
WC Acupuncture Therapy; Aged; Bone Neoplasms; complications; Carcinoma, Hepatocellular; pathology; Female; Home Care Services; Humans; Liver Neoplasms; pathology; Neoplasms; pathology; Neuralgia; etiology; Quality of Life
UT PubMed:29691187
PM 29691187
DA 2018-04-25
ER

PT J
AU Sun, ZR
   Lü, XL
   Yin, HN
   Hao, JS
   Zeng, XX
   Li, ZX
AF Sun, Zhong-Ren
   Lü, Xiao-Lin
   Yin, Hong-Na
   Hao, Ji-Shun
   Zeng, Xiang-Xin
   Li, Zhu-Xin
TI [Progress of Researches on Mechanisms of Acupuncture Therapy in Regulating Brain
SO Zhen ci yan jiu = Acupuncture research
LA chi
DT Review
DE Acupuncture; Brain plasticity; Mechanism research; Protein expression
AB Brain plasticity is referred to the ability of the brain to change in structure  and functional activities from microscopic aspects (synapses) in individual  neurons to larger-scale aspects such as cortical remapping, neuronal remodeling,  etc. in response to injury. Acupuncture has a positive effect in the treatment of  cerebral diseases, thus leading to an increasing research on its underlying  mechanisms in regulating brain plasticity. The present paper reviewed recent  development of studies on acupuncture treatment of Alzheimer's disease, vascular  dementia, cerebral ischemia, bone cancer pain, autism, etc. from 1) regulating  synaptic plasticity (up-regulating the proportion of hippocampal synapses,  increasing synaptic curvature, post-synaptic density, and numerical density,  areal density, and lowering synaptic cleft); 2) increasing hippocampal  post-synaptic potential slop, peak and peak area of population spikes to evoke  long-term potentiation (LTP) by regulating the expression of glutamate  N-methyl-D-aspartate (NMDA) and alpha  amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors, and growth  associated protein (GAP-43); 3) down-regulating the expression of glial  fibrillary acidic protein (GFAP) to suppress the activity of astrocytes in the  ischemic cerebral area and hippocampus in cerebral ischemia rats, and in the  spinal cord dorsal horns of bone cancer rats, etc. and promoting vimentin and  connexin 43 expression; and 4) promoting neuronal remodeling, and repair and  regeneration of the injured nerve in the central nervous system via regulating  neuron-glia network, expression of nerve growth factor, brain derived  neurotrophic factor, etc. The future studies should pay more attention to 1) the  contribution of acupuncture intervention to the correlation between the  initiation of the endogenous protective effect and the brain plasticity during  the onset of nerve injury and repair of the injured nerve, and 2) standarization  of stimulating quantity, manipulation and duration of acupuncture treatment, as  well as the relationship between the stimulating quantity and efficacy.
C1 Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China.
   The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150001.
   The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150001.
   American International Neural Acupuncture and Moxibustion Institution, New Mexico, USA.
   The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150001.
   Graduate School of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040.
NR 0
TC 0
SN 
EI 1000-060
J9 Zhen Ci Yan Jiu
PD OCT 27
PY 2018
VL 43
IS 10
BP 674
EP 7
DI 10.13702/j.1000-0607.170039
PG -667
WC Acupuncture Therapy; Animals; Brain; Hippocampus; Humans; Neuronal Plasticity; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses
UT PubMed:30365266
PM 30365266
DA 2018-10-27
ER

PT J
AU Lyman, GH
   Greenlee, H
   Bohlke, K
   Bao, T
   DeMichele, AM
   Deng, GE
   Fouladbakhsh, JM
   Gil, B
   Hershman, DL
   Mansfield, S
   Mussallem, DM
   Mustian, KM
   Price, E
   Rafte, S
   Cohen, L
AF Lyman, Gary H.
   Greenlee, Heather
   Bohlke, Kari
   Bao, Ting
   DeMichele, Angela M.
   Deng, Gary E.
   Fouladbakhsh, Judith M.
   Gil, Brigitte
   Hershman, Dawn L.
   Mansfield, Sami
   Mussallem, Dawn M.
   Mustian, Karen M.
   Price, Erin
   Rafte, Susan
   Cohen, Lorenzo
TI Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement of the SIO Clinical Practice Guideline
SO JOURNAL OF CLINICAL ONCOLOGY
LA English
DT Article
ID induced peripheral neuropathy; estrogen-receptor-alpha; american society; chemotherapy; survivors; ginseng; acupressure; management; nausea; trial
AB PurposeThe Society for Integrative Oncology (SIO) produced an evidence-based guideline on use of integrative therapies during and after breast cancer treatment that was determined to be relevant to the American Society of Clinical Oncology (ASCO) membership. ASCO considered the guideline for endorsement.MethodsThe SIO guideline addressed the use of integrative therapies for the management of symptoms and adverse effects, such as anxiety and stress, mood disorders, fatigue, quality of life, chemotherapy-induced nausea and vomiting, lymphedema, chemotherapy-induced peripheral neuropathy, pain, and sleep disturbance. Interventions of interest included mind and body practices, natural products, and lifestyle modifications. SIO systematic reviews focused on randomized controlled trials that were published from 1990 through 2015. The SIO guideline was reviewed by ASCO content experts for clinical accuracy and by ASCO methodologists for developmental rigor. On favorable review, an ASCO Expert Panel was convened to review the guideline contents and recommendations.ResultsThe ASCO Expert Panel determined that the recommendations in the SIO guidelinepublished in 2017are clear, thorough, and based on the most relevant scientific evidence. ASCO endorsed the guideline with a few added discussion points.RecommendationsKey recommendations include the following: Music therapy, meditation, stress management, and yoga are recommended for anxiety/stress reduction. Meditation, relaxation, yoga, massage, and music therapy are recommended for depression/mood disorders. Meditation and yoga are recommended to improve quality of life. Acupressure and acupuncture are recommended for reducing chemotherapy-induced nausea and vomiting. Acetyl-l-carnitine is not recommended to prevent chemotherapy-induced peripheral neuropathy because of a possibility of harm. No strong evidence supports the use of ingested dietary supplements to manage breast cancer treatment-related adverse effects. Additional information is available at: www.asco.org/supportive-care-guidelines.
C1 [Lyman, Gary H.; Greenlee, Heather] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
   [Lyman, Gary H.; Greenlee, Heather] Univ Washington, Seattle, WA 98195 USA.
   [Bohlke, Kari] Amer Soc Clin Oncol, Alexandria, VA USA.
   [Bao, Ting; Deng, Gary E.] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA.
   [Hershman, Dawn L.] Columbia Univ, Med Ctr, New York, NY USA.
   [Mustian, Karen M.] Univ Rochester, Med Ctr, Rochester, NY 14642 USA.
   [DeMichele, Angela M.] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.
   [Fouladbakhsh, Judith M.] Oakland Univ, Rochester, MI 48063 USA.
   [Gil, Brigitte] Lahey Hosp & Med Ctr, Burlington, MA USA.
   [Mansfield, Sami] Canc Wellness Life, Shawnee, KS USA.
   [Mansfield, Sami] Sarah Cannon Canc Inst, Kansas City, MO USA.
   [Mussallem, Dawn M.] Mayo Clin, Jacksonville, FL 32224 USA.
   [Price, Erin] Smith Ctr Healing & Arts, Washington, DC USA.
   [Cohen, Lorenzo] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA.
C3 Fred Hutchinson Cancer Center; University of Washington; University of Washington Seattle; American Society of Clinical Oncology; Memorial Sloan Kettering Cancer Center; Columbia University; University of Rochester; University of Pennsylvania; Oakland University; Lahey Hospital & Medical Center; Sarah Cannon Research Institute; Mayo Clinic; University of Texas System; UTMD Anderson Cancer Center
RP Lyman, GH (corresponding author), Amer Soc Clin Oncol, 2318 Mill Rd,Suite 800, Alexandria, VA 22314 USA.
EM guidelines@asco.org
FU Amgen (Inst); Pfizer (Inst); Genentech (Inst); Incyte (Inst); Veridex (Inst); Calithera Biosciences (Inst)
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NR 39
TC 294
Z9 333
U1 6
U2 139
PU AMER SOC CLINICAL ONCOLOGY
PI ALEXANDRIA
PA 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA
SN 0732-183X
EI 1527-7755
J9 J CLIN ONCOL
JI J. Clin. Oncol.
PD SEP 1
PY 2018
VL 36
IS 25
BP 2647
EP +
DI 10.1200/JCO.2018.79.2721
PG 11
WC Oncology
SC Oncology
GA GU9MB
UT WOS:000445669200011
PM 29889605
DA 2026-01-16
ER

PT J
AU Bao, T
   Li, SSQ
   Dearing, JL
   Piulson, LA
   Seluzicki, CM
   Sidlow, R
   Mao, JJ
AF Bao, Ting
   Li, Susan Q.
   Dearing, Josh L.
   Piulson, Lauren A.
   Seluzicki, Christina M.
   Sidlow, Robert
   Mao, Jun J.
TI Acupuncture versus medication for pain management: a cross-sectional study of breast cancer survivors
SO ACUPUNCTURE IN MEDICINE
LA English
DT Article
DE acupuncture; pain management; complementary medicine; oncology
ID alternative medicine use; aromatase inhibitors; cost-effectiveness; randomized-trial; persistent pain; joint symptoms; risk-factors; complementary; prevalence; women
AB Aim of the study Breast cancer survivors who take aromatase inhibitors (AI) often suffer from chronic pain. Emerging evidence supports the use of acupuncture as an effective pain management strategy for this condition, but its acceptability among cancer survivors is unknown. We evaluated breast cancer survivors' preferences for acupuncture as compared with medication use and identified factors predictive of this preference. Methods We conducted a cross-sectional study among breast cancer survivors who were currently, or had been, taking an AI. The primary outcome was degree of preference for acupuncture as compared with medication for pain management. We conducted multivariate logistic regression analyses to evaluate the effects of socioeconomic status (SES) factors and health beliefs on treatment preference. Results Among 592 participants, 160 (27.0%) preferred acupuncture, 153 (25.8%) preferred medication and 279 (47.1%) had no clear preference. In a multivariate analysis that only included SES, higher education and white race were significantly associated with greater preference for acupuncture. When health beliefs were added, SES effects were attenuated, while greater expectation of acupuncture's effect, lower perceived barriers to its use, higher social norm (endorsement from family members and healthcare professionals) related to acupuncture and higher holistic health beliefs were associated with greater preference for acupuncture. Conclusion We found similar rates of preference for acupuncture versus medication among breast cancer survivors for pain management. Specific attitudes and beliefs predicted such preferences, highlighting the importance of a patient-centred approach to align patient beliefs and preferences with therapeutic options for more effective pain management. Trial registration number NCT01013337; Results.
C1 [Bao, Ting; Li, Susan Q.; Dearing, Josh L.; Piulson, Lauren A.; Seluzicki, Christina M.; Mao, Jun J.] Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1275 York Ave, New York, NY 10021 USA.
   [Sidlow, Robert] Mem Sloan Kettering Canc Ctr, Div Survivorship & Support Care, 1275 York Ave, New York, NY 10021 USA.
C3 Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center
RP Bao, T (corresponding author), Mem Sloan Kettering Canc Ctr, Integrat Med & Breast Med Serv, 1275 York Ave, New York, NY 10021 USA.
EM baot@mskcc.org
FU National Cancer Institute [R01CA158243, R21CA173263]; Memorial Sloan Kettering Cancer Center P30 grant [P30-CA008748]; Byrne Fund at Memorial Sloan Kettering Cancer Center; National Cancer Institute [P30CA008748] Funding Source: NIH RePORTER
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NR 31
TC 26
Z9 28
U1 0
U2 33
PU BMJ PUBLISHING GROUP
PI LONDON
PA BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
SN 0964-5284
EI 1759-9873
J9 ACUPUNCT MED
JI Acupunct. Med.
PD APR 15
PY 2018
VL 36
IS 2
BP 80
EP 87
DI 10.1136/acupmed-2017-011435
PG 8
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GC4CB
UT WOS:000429729700003
PM 29440043
DA 2026-01-16
ER

PT J
AU Lee, YC
   Lin, CH
   Hung, SY
   Chung, HY
   Luo, ST
   MacDonald, I
   Chu, YT
   Lin, PL
   Chen, YH
AF Lee, Yu-Chen
   Lin, Chia-Hsien
   Hung, Shih-Ya
   Chung, Hsin-Yi
   Luo, Sih-Ting
   MacDonald, Iona
   Chu, Yu-Ting
   Lin, Pei-Lin
   Chen, Yi-Hung
TI Manual acupuncture relieves bile acid-induced itch in mice: the role of microglia and TNF-α
SO INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
LA English
DT Article
DE acupuncture; pruritogen; microglial activation; spinal cord; cholestatic pruritus
ID h-1 receptor antagonists; i hypersensitivity itch; c-fos expression; scratching behavior; neuropathic pain; proliferation; minocycline; modulation; activation; pruritus
AB Pruritus, or itch, is a frequent complaint amongst patients with cholestatic hepatobiliary disease and is difficult to manage, with many patients refractory to currently available antipruritic treatments. In this study, we examined whether manual acupuncture (MA) at particular acupoints represses deoxycholic acid (DCA)-induced scratching behavior and microglial activation and compared these effects with those induced by another pruritogen, 5'-guanidinonaltrindole (GNTI, a kappa opioid receptor antagonist). MA at Hegu (LI4) and Quchi (LI11) acupoints significantly attenuated DCA- and GNTI-induced scratching, whereas no such effects were observed at the bilateral Zusanli acupoints (ST36). Interestingly, GNTI-induced scratching was reduced similarly by both MA and electroacupuncture (EA) at the LI4 and LI11 acupoints. MA at non-acupoints did not affect scratching behavior. Intraperitoneal injection of minocycline (a microglial inhibitor) reduced GNTI- and DCA-induced scratching behavior. In Western blot analysis, subcutaneous DCA injection to the back of the neck increased spinal cord expression of ionized calcium-binding adapter molecule 1 (Iba1) and tumor necrosis factor-alpha (TNF-alpha) as compared with saline injection, while MA at LI4 and LI11 reduced these DCA-induced changes. Immunofluorescence confocal microcopy revealed that DCA-induced Iba1 -positive cells with thicker processes emanated from the enlarged cell bodies, while this effect was attenuated by pretreatment with MA. It is concluded that microglia and TNF-alpha play important roles in the itching sensation and MA reduces DCA-induced scratching behavior by alleviating spinal microglial activation. MA may be an effective treatment for cholestatic pruritus.
C1 [Lee, Yu-Chen] China Med Univ Hosp, Dept Acupuncture, Taichung 40402, Taiwan.
   [Lee, Yu-Chen; Chung, Hsin-Yi; Luo, Sih-Ting; MacDonald, Iona; Chu, Yu-Ting; Chen, Yi-Hung] China Med Univ, Grad Inst Acupuncture Sci, Taichung 40402, Taiwan.
   [Lin, Chia-Hsien] Kainan Univ, Dept Hlth Ind Management, 1 Kainan Rd, Taoyuan 33857, Taiwan.
   [Hung, Shih-Ya] China Med Univ, Dept Med Lab Sci & Biotechnol, Taichung 40402, Taiwan.
   [Lin, Pei-Lin] Natl Taiwan Univ Hosp, Dept Anesthesiol, Taipei 10002, Taiwan.
   [Chen, Yi-Hung] China Med Univ, Chinese Med Res Ctr, Taichung 40402, Taiwan.
   [Chen, Yi-Hung] Asia Univ, Dept Photon & Commun Engn, Taichung, Taiwan.
C3 China Medical University Taiwan; China Medical University Hospital - Taiwan; China Medical University Taiwan; Kainan University; China Medical University Taiwan; National Taiwan University; National Taiwan University Hospital; China Medical University Taiwan; Asia University Taiwan
RP Chen, YH (corresponding author), China Med Univ, Grad Inst Acupuncture Sci, Taichung 40402, Taiwan.; Lin, PL (corresponding author), Natl Taiwan Univ Hosp, Dept Anesthesiol, Taipei 10002, Taiwan.; Chen, YH (corresponding author), China Med Univ, Chinese Med Res Ctr, Taichung 40402, Taiwan.; Chen, YH (corresponding author), Asia Univ, Dept Photon & Commun Engn, Taichung, Taiwan.
EM pll5611@ntu.edu.tw; yihungchen@mail.cmu.edu.tw
FU Ministry of Science and Technology, Taipei, Taiwan [MOST104-2320-B-039-020-MY2, 106-2320-B-039-019-]; China Medical University Hospital, Taiwan [DMR-106-004]; "Chinese Medicine Research Center, China Medical University" from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project under the Ministry of Education (MOE) in Taiwan
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NR 51
TC 18
Z9 19
U1 0
U2 14
PU IVYSPRING INT PUBL
PI LAKE HAVEN
PA PO BOX 4546, LAKE HAVEN, NSW 2263, AUSTRALIA
SN 1449-1907
EI 
J9 INT J MED SCI
JI Int. J. Med. Sci.
PD JUN 15
PY 2018
VL 15
IS 9
BP 953
EP 960
DI 10.7150/ijms.24146
PG 8
WC Medicine, General & Internal
SC General & Internal Medicine
GA GM6IH
UT WOS:000438268100012
PM 30008609
DA 2026-01-16
ER

PT J
AU Lemanne, D
   Maizes, V
AF Lemanne, Dawn
   Maizes, Victoria
TI Advising Women Undergoing Treatment for Breast Cancer: A Narrative Review
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Review
DE cancer; integrative therapies; nutrition; dietary supplements; intermittent fasting; stress management
ID follow-up; all-cause; adjuvant chemotherapy; integrative therapy; coffee consumption; physical-activity; controlled-trial; supplement use; survivors; exercise
AB A majority of women undergoing conventional treatment for breast cancer also undertake complementary and integrative approaches. Practitioners knowledgeable about the evidence base behind common integrative approaches can help patients attain improved quality of life, and at times, improved survival. Evidence-based recommendations include the following: a plant-based diet for general health after diagnosis, and carbohydrate restriction for patients with estrogen receptor-positive postmenopausal breast cancer may be prudent. Other dietary recommendations include a 13-h daily overnight fast. Carefully selected patients may choose to fast the day before and the day of chemotherapy to decrease side effects. Specific food recommendations include avoidance or limitation of alcohol, and liberal culinary use of cruciferous vegetables, coffee, green tea, soy, and flaxseed. Promising supplements include diindolylmethane and melatonin. Omega 3 fatty acids may help with bone density in patients on aromatase inhibitors, but may increase chemotherapy resistance. Findings regarding the usefulness of multivitamins, vitamin D, vitamin C, and vitamin E are weak and/or mixed different exercise modalities may have different effects and thus play different roles in breast cancer therapy. Aerobic and resistance training combined during breast cancer chemotherapy may confer a survival benefit, while yoga may improve outcome in lymphedema patients. Current evidence suggests that meditation, yoga, breathing, music therapy, guided imagery, and hypnosis may improve mood and quality of life during breast cancer treatment. Acupuncture is useful for treating side effects of breast cancer therapies, including hot flushes, aromatase inhibitor-induced joint pain, chemotherapy-induced peripheral neuropathy, and vulvodynia. Vaginal moisturizers and vaginal rings supplying low-dose estrogen can be useful in the treatment of symptoms of estrogen-deprivation states caused by breast cancer treatments; such symptoms include vaginal dryness, dyspareunia, and sexual dysfunction. Carbon dioxide laser technology can rejuvenate atrophied vaginal mucosa and relieve dyspareunia, allowing avoidance of estrogen therapy. Tertiary sexual health centers are available for referral.
C1 [Lemanne, Dawn; Maizes, Victoria] Univ Arizona, Ctr Integrat Med, 1249N Mt Ave,POB 245153, Tucson, AZ 85724 USA.
   [Lemanne, Dawn] Oregon Integrat Oncol, Ashland, OR USA.
   [Lemanne, Dawn] Natl Inst Integrat Med, Melbourne, Vic, Australia.
C3 University of Arizona; National Institute of Integrative Medicine - Australia
RP Maizes, V (corresponding author), Univ Arizona, Ctr Integrat Med, 1249N Mt Ave,POB 245153, Tucson, AZ 85724 USA.
EM vmaizes@email.arizona.edu
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NR 79
TC 10
Z9 14
U1 0
U2 47
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD SEP 15
PY 2018
VL 24
IS 9-10
BP 902
EP 909
DI 10.1089/acm.2018.0150
PG 8
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GU6VP
UT WOS:000445455600007
PM 30247957
DA 2026-01-16
ER

PT J
AU Su, CF
AF Su, Ching-Feng
TI Home care with acupuncture increased the quality of life in a patient with advanced cancer with neuropathic pain induced by bone metastasis: a case report
SO JOURNAL OF INTEGRATIVE MEDICINE-JIM
LA English
DT Article
DE Acupuncture; Case report; Cancer; Neuropathic pain; Quality of life; Hospice care; Palliative care
ID peripheral neuropathy; etiology; burden; impact
AB A 66-year-old female patient was diagnosed with hepatocellular carcinoma accompanied by neuropathic pain induced by a metastatic tumor that compromised root and spinal canal. Although her pain was relieved following medical treatment, breakthrough pain occurring 1-2 times a day was still distressing. Neuropathic pain in her right lower limb caused discomfort and irritability and decreased her quality of life. We had limited options to adjust her prescription drug regime, due to the side effect of these drugs. Although acupuncture therapy was only performed at her home once a week, the efficacy was outstanding. The patient did not report any further instances of breakthrough pain, and she did not require additional bolus morphine. She could comfortably live in her familiar surroundings with her family and did not require any emergency room visits or admission into the hospital during the last month of her life. She had excellent quality of life in the terminal period of her life, and could even participate in a family function during this time. The present case report suggests that acupuncture may have a role in treating neuropathic pain induced by bone metastasis in patients with advanced cancer across clinical and in-home settings. (C) 2018 Shanghai Changhai Hospital. Published by Elsevier B.V. All rights reserved.
C1 [Su, Ching-Feng] Pingtung Christian Hosp, Dept Family Med, Pingtung 900, Pingtung County, Taiwan.
RP Su, CF (corresponding author), Pingtung Christian Hosp, Dept Family Med, Pingtung 900, Pingtung County, Taiwan.
EM 04836@ptch.org.tw
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NR 22
TC 5
Z9 9
U1 1
U2 18
PU ELSEVIER
PI AMSTERDAM
PA RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
SN 2095-4964
EI 
J9 J INTEGR MED-JIM
JI J. Integr. Med.-JIM
PD MAY 15
PY 2018
VL 16
IS 3
BP 208
EP 210
DI 10.1016/j.joim.2018.04.003
PG 3
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GG4LZ
UT WOS:000432669500010
PM 29691187
DA 2026-01-16
ER

PT J
AU Serçe, S
   Ovayolu, Ö
   Pirbudak, L
   Ovayolu, N
AF Serce, Sibel
   Ovayolu, Ozlem
   Pirbudak, Lutfiye
   Ovayolu, Nimet
TI The Effect of Acupressure on Pain in Cancer Patients With Bone Metastasis: A Nonrandomized Controlled Trial
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE cancer; pain; metastasis; radiotherapy; acupressure; nursing
ID quality-of-life; symptom management; analgesia; myeloma; breast
AB Background: Pain is a serious and common problem in bone metastases. For this purpose, complementary and supportive practices are also applied along with medical treatment. This study was conducted for the purpose of evaluating the effect of acupressure on pain in cancer patients with bone metastasis. Methods: The study was conducted in a nonrandomized controlled trial with patients who applied to the radiotherapy unit of an oncology hospital. The data of the study were collected by using a questionnaire and the Visual Analog Scale. A total of 8 acupressure sessions, which lasted for approximately 10 minutes each (with warming and acupressure periods), was applied to the intervention group. The data were analyzed by using (2) test, paired t test, and Pearson's correlation coefficient. Results: It was determined that the pain mean score of the intervention group was 7.6 +/- 1.9 before the acupressure and decreased to 6.8 +/- 1.9 after the acupressure and this result was statistically significant. On the other hand, no significant difference was determined in the pain mean score of the control group. Conclusions: Acupressure is applicable for cancer patients with bone metastasis by nursing staff after receiving brief training and may make a difference in relieving pain of the patients. Further well-designed trials should be conducted.
C1 [Serce, Sibel] Gaziantep Univ Hosp, Gaziantep, Turkey.
   [Ovayolu, Ozlem; Ovayolu, Nimet] Gaziantep Univ, Dept Nursing, Fac Hlth Sci, TR-27310 Gaziantep, Turkey.
   [Pirbudak, Lutfiye] Gaziantep Univ, Sch Med, Gaziantep, Turkey.
C3 Gaziantep University; Gaziantep University; Gaziantep University
RP Ovayolu, Ö (corresponding author), Gaziantep Univ, Dept Nursing, Fac Hlth Sci, TR-27310 Gaziantep, Turkey.
EM oucan@gantep.edu.tr
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   Turk AGG, 2006, HACETTEPE UNIVERSITESI HEMSIRELIK YUKSEKOKULU DERGISI, V13, P43
   Ucan O, 2007, FIRAT SAGLIK HIZMETLERI DERGISI, V2, P123
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   Zick SM, 2012, BMC COMPLEM ALTERN M, V12, P0, DOI 10.1186/1472-6882-12-132
NR 30
TC 15
Z9 17
U1 0
U2 11
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD SEP 15
PY 2018
VL 17
IS 3
BP 728
EP 736
DI 10.1177/1534735418769153
PG 9
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA GQ8BY
UT WOS:000441976400015
PM 29649905
DA 2026-01-16
ER

PT J
AU Wang, MM
   Yu, XH
   Geng, W
   Cui, HF
   Wang, CC
   Han, J
   Yang, DH
AF Wang, Meng-Meng
   Yu, Xiao-Hua
   Geng, Wei
   Cui, Hua-Feng
   Wang, Chang-Chun
   Han, Jing
   Yang, Dian-Hui
TI [Effect of Manual Acupuncture Preconditioning on Behavior and Contents of Serum
SO Zhen ci yan jiu = Acupuncture research
LA chi
DT Journal Article
DE Behavioral score; Calcitonin gene-related peptide; Liver-soothing and mental-activity-regulating needling; Manual acupuncture; Migraine; Substance P; Tumor necrosis factor-α; interleukin-1 β
AB OBJECTIVE: To observe the effect of liver-soothing and mental-activity-regulating  (LSMAR) needling on behavior reactions and contents of serum calcitonin  gene-related peptide (CGRP), substance P (SP), interleukin-1 β (IL-1 β) and tumor  necrosis factor-α (TNF-α) in migraine rats, so as to explore its mechanism  underlying relief of migraine. METHODS: Thirty-two male Wistar rats were randomly  divided into control, model, LSMAR needling and conventional needling groups (n=8  rats in each). The migraine model was established by hypodermic injection of  glyceryl trinitrate (5 mg/kg) at the napex. Acupuncture preconditioning was  conducted once daily for 8 days before modeling. Acupuncture needles were  inserted into "Baihui" (GV 20), and bilateral "Fengchi" (GB 20), "Neiguan" (PC 6)  and "Taichong" (LR 3), manipulated for a while and retained for 30 min. The rats'  behavioral changes (times of head scratching, tail-biting, cage-crawling, and to-  and fro-movement in 30 min) were scored (one symptom = one point) before  modeling, after modeling, and after intervention. The concentrations of CGRP, SP,  IL-1 β, TNF-α in serum were assayed by enzyme-linked immunosorbent assay (ELISA).  RESULTS: After modeling, the behavioral scores were significantly increased in  the migraine model rats relevant to the control group (P<0.05). Whereas after the  treatment, the behavior scores were considerably decreased during 60-90 min and  120-150 min of the measuring period in both LSMAR and conventional needling  groups compared with the model group (P<0.05). The concentrations of CGRP, SP,  IL-1 β and TNF-α were significantly higher in the model group than in the control  group (P<0.05), and notably lower in both LSMAR and conventional needling groups  than in the model group (P<0.05). The therapeutic effect of LSMAR was markedly  superior to that of conventional needling in down-regulating the concentrations  of CGRP, SP, IL-1 β and TNF-α (P<0.05). CONCLUSION: Acupuncture preconditioning  can effectively relieve pain in migraine rats possibly by decreasing the  concentrations of CGRP, SP, IL-1 β and TNF-α in the peripheral blood, and the  therapeutic effect of LSMAR is evidently superior to that of conventional  needling.
C1 College of Acupuncture-moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan 250014, China.
   College of Acupuncture-moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan 250014, China
   Department of Acupuncture and Moxibustion,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011.
   Department of Traditional Chinese Medicine, Shandong Maternal and Child Health Care Hospital, Jinan 250014.
   Department of Acupuncture and Moxibustion, the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011.
   Department of Acupuncture and Moxibustion, the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011.
   College of Acupuncture-moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan 250014, China
   Department of Acupuncture and Moxibustion,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011.
   College of Acupuncture-moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan 250014, China
   Shandong Provincial Key Laboratory ofTraditional Chinese Medicine, the Acupuncture Neurobio-logy Laboratory, Jinan250355.
NR 0
TC 0
SN 
EI 1000-060
J9 Zhen Ci Yan Jiu
PD AUG 10
PY 2018
VL 43
IS 6
BP 375
EP 9
DI 10.13702/j.1000-0607.170415
PG -366
WC Acupuncture Therapy; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Interleukin-1beta; Male; Migraine Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substance P; Tumor Necrosis Factor-alpha
UT PubMed:30091544
PM 30091544
DA 2018-08-10
ER

PT J
AU Zhi, WI
   Ingram, E
   Li, SQ
   Chen, P
   Piulson, L
   Bao, T
AF Zhi, W Iris
   Ingram, Evan
   Li, Susan Qing
   Chen, Patricia
   Piulson, Lauren
   Bao, Ting
TI Acupuncture for Bortezomib-Induced Peripheral Neuropathy: Not Just for Pain.
SO Integrative cancer therapies
LA English
DT Journal Article
DE acupuncture; bortezomib; multiple myeloma; peripheral neuropathy
AB BACKGROUND: Bortezomib-induced peripheral neuropathy (BIPN) is a common and  debilitating side effect. Our pilot study demonstrated that acupuncture is safe  and can decrease total neuropathic symptoms. However, there is lack of knowledge  in which individual BIPN symptoms benefited from acupuncture. PURPOSE: To  characterize individual symptoms reduced by acupuncture in patients with BIPN.  METHODS: Patients with multiple myeloma treated with bortezomib who developed  BIPN grade 2 or above, based on National Cancer Institute Common Terminology  Criteria for Adverse Events (NCI CTCAE), were enrolled and received 10  acupuncture treatments over 10 weeks. Self-reported BIPN-associated symptoms  assessments were collected weekly at baseline, during, and after acupuncture  treatment using the Neuropathy Pain Scale (NPS) and the Functional Assessment of  Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (FACT/GOG-Ntx)  questionnaires. Changes in individual symptoms were analyzed based on  FACT/GOG-Ntx and NPS scores. RESULTS: There were statistically significant  reductions in individual symptoms in both NPS and FACT/GOG-Ntx. The FACT/GOG-Ntx  reductions were most pronounced in hand/feet numbness/tingling, discomfort, and  trouble walking. The sensory symptoms, such as tingling and numbness, especially  in the feet, reduced the most ( P < .0001), and motor dysfunction also reduced  significantly ( P = .0001). Both hearing and dysfunction scores were also  statistically significantly increased, indicating improved symptoms. The NPS  scores showed significant symptom relief in all 10 items from the NPS assessment,  particularly in cold sensitivity and an unpleasant feeling. CONCLUSIONS:  Acupuncture can improve multiple symptoms associated with BIPN, particularly  numbness and tingling in hands and feet, cold sensitivity, and an unpleasant  feeling. Further randomized control trials are warranted to confirm our findings.
C1 1 Memorial Sloan Kettering Cancer Center, New York, NY, USA.
   2 University of Toledo, Toledo, OH, USA.
   1 Memorial Sloan Kettering Cancer Center, New York, NY, USA.
   1 Memorial Sloan Kettering Cancer Center, New York, NY, USA.
   1 Memorial Sloan Kettering Cancer Center, New York, NY, USA.
   1 Memorial Sloan Kettering Cancer Center, New York, NY, USA.
NR 0
TC 0
SN 1552-695
EI 1534-735
J9 Integr Cancer Ther
PD JUL 22
PY 2018
VL 17
IS 4
BP 1079
EP 1086
DI 10.1177/1534735418788667
PG 7
WC Acupuncture; methods; Acupuncture Therapy; methods; Aged; Bortezomib; adverse effects; Female; Humans; Male; Middle Aged; Multiple Myeloma; drug therapy; Pain; physiopathology; Pain Measurement; methods; Peripheral Nervous System Diseases; chemically induced; Pilot Projects
UT PubMed:30027756
PM 30027756
DA 2018-07-22
ER

PT J
AU McPhail, P
   Sandhu, H
   Dale, J
   Stewart-Brown, S
AF McPhail, P.
   Sandhu, H.
   Dale, J.
   Stewart-Brown, S.
TI Acupuncture in hospice settings: A qualitative exploration of patients' experiences
SO EUROPEAN JOURNAL OF CANCER CARE
LA English
DT Article
DE acupuncture; grounded theory; hospice; qualitative; well-being
ID palliative care; symptom management; cancer; complementary; intervention
AB Whilst acupuncture has the potential to impact on many aspects of health and well-being, including end-of-life care, there is little research regarding patients' experiences of its effects within the context of palliative care in hospice settings. The aim of this study was to address this gap, by exploring patients' experiences of acupuncture within this setting. In-depth, semi-structured interviews were conducted with a sample of eighteen patients who had received acupuncture as part of hospice care. Transcription of data, with thematic analysis, identified two overarching themes: (1) participant perceptions of the effects of acupuncture including pain control, improved physical and emotional health, spiritual well-being and awareness of health as a holistic phenomenon; and (2) factors which participants believed enabled acupuncture to have these effects including the quality of the practitioner relationship, engagement of participants in the process of their treatment and prior expectations that acupuncture could work. Acupuncture was found to be a highly acceptable, accessible and popular treatment with positive holistic effects reported across the domains of physical, mental and spiritual health and no serious adverse effects. By enabling awareness ofthe holistic nature of health and well-being, acupuncture was experienced as havingthe potential to contribute to a better death, an emergent theory that needs testing in further studies. In the meanwhile, the results of this study offer encouragement to hospices currently providing or considering investing in acupuncture provision.
C1 [McPhail, P.] Univ Warwick, Warwick Med Sch, Div Hlth Sci, Coventry, W Midlands, England.
   [Dale, J.] Univ Warwick, Warwick Med Sch, Div Hlth Sci, Primary Care, Coventry, W Midlands, England.
   [Stewart-Brown, S.] Univ Warwick, Warwick Med Sch, Div Hlth Sci, Publ Hlth, Coventry, W Midlands, England.
   [Sandhu, H.] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Div Hlth Sci, Coventry, W Midlands, England.
C3 University of Warwick; University of Warwick; University of Warwick; University of Warwick
RP McPhail, P (corresponding author), Univ Warwick, Warwick Med Sch, Div Hlth Sci, Coventry, W Midlands, England.
EM paulahearle@hotmail.co.uk
CR Alfred A, 2011, AUST FAM PHYSICIAN, V40, P718
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NR 34
TC 10
Z9 12
U1 1
U2 7
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0961-5423
EI 1365-2354
J9 EUR J CANCER CARE
JI Eur. J. Cancer Care
PD MAR 15
PY 2018
VL 27
IS 2
BP 
EP 
DI 10.1111/ecc.12802
PG 9
WC Oncology; Health Care Sciences & Services; Nursing; Rehabilitation
SC Oncology; Health Care Sciences & Services; Nursing; Rehabilitation
GA GA4SH
UT WOS:000428321300039
PM 29323766
DA 2026-01-16
ER

PT J
AU Kim, K
   Lee, S
AF Kim, Kyungsuk
   Lee, Sanghun
TI Intradermal Acupuncture Along with Analgesics for Pain Control in Advanced Cancer Cases: A Pilot, Randomized, Patient-Assessor-Blinded, Controlled Trial
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE acupuncture; intradermal; advanced cancer; analgesics; pain management
ID quality-of-life; cell lung-cancer; auricular acupuncture; clinical-trials; sample-size; management; complementary; prevalence; medicine; qlq-c30
AB Purpose: Ninety percent of patients with advanced cancer have moderate to severe pain, and up to 70% of patients with cancer pain do not receive adequate pain relief. This randomized controlled clinical trial was designed to determine the feasibility and evaluate the effects and safety of intradermal acupuncture (IA) in patients who were being administered analgesics for cancer pain. Methods: Advanced cancer patients experiencing pain were randomly assigned to IA or sham IA treatment for 3 weeks (15 patients for each group), wherein the CV12, bilateral ST25, LI4, LR3, PC06, and Ashi points were selected and stimulated. Follow-up evaluations were conducted 3 weeks after the end of treatments. The grade and dosage of analgesics for cancer pain, pain intensity, quality of life, and safety were assessed. Results: Twenty-seven patients (90%) completed 6-week trial, and no serious adverse events were associated with either IA or sham IA procedures except the transient side effect such as fatigue. Nine patients in the IA group (64.3%) and 5 in the sham IA group (38.5%) responded to the 3-week intervention. These patients were mostly in the nonopioid and the weak opioid levels of the World Health Organization analgesic ladder. Self-reported pain declined by -1.54 +/- 1.45 and -1.15 +/- 1.57 in the IA and sham IA groups, respectively, with improved quality of life reported. Conclusions: IA treatment appears feasible and safe for advanced cancer patients. It might reduce analgesic usage in the early World Health Organization analgesic ladder stage cancer patient, though it could not show significant outcome differences due to design limitation of sham IA.
C1 [Kim, Kyungsuk; Lee, Sanghun] Dankook Univ, Grad Sch, Dept Med Consilience, 152 Jukjeon Ro, Yongin 16890, Gyeonggi Do, South Korea.
C3 Dankook University
RP Lee, S (corresponding author), Dankook Univ, Grad Sch, Dept Med Consilience, 152 Jukjeon Ro, Yongin 16890, Gyeonggi Do, South Korea.
EM integrative@korea.com
FU Ministry of Science, ICT and Future Planning through the National Research Foundation [NRF-2017M3A9C4065964]; Comprehensive and Integrative Medicine Institute (CIMI), Daegu, Republic of Korea [CIMI-15-01-07]
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NR 33
TC 30
Z9 37
U1 1
U2 35
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD DEC 15
PY 2018
VL 17
IS 4
BP 1137
EP 1143
DI 10.1177/1534735418786797
PG 7
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA HA5OG
UT WOS:000450322400016
PM 30009652
DA 2026-01-16
ER

PT J
AU Sand-Jecklin, K
   Reiser, V
AF Sand-Jecklin, Kari
   Reiser, Victoria
TI Use of Seva Stress Release Acupressure to Reduce Pain, Stress, and Fatigue in Patients Hospitalized for Cancer Treatment
SO JOURNAL OF HOSPICE & PALLIATIVE NURSING
LA English
DT Article
DE acupressure; complementary and alternative medicine (CAM); fatigue; integrative; pain; stress; symptom
ID symptom cluster; anxiety; acupuncture; management; impact
AB Patients undergoing treatment for cancer often experience stress, fatigue, and pain during their treatment. Medical management of these symptoms can cause additional adverse effects, but it is possible that noninvasive complementary therapies may be able to reduce these symptoms without unwanted adverse effects. The purpose of this study was to assess the feasibility and impact of the Seva Stress Release acupressure protocol on stress, fatigue, pain, and vital signs of patients hospitalized for cancer treatment. Thirty patients receiving cancer treatment and experiencing stress, fatigue, and pain were recruited for the study. After obtaining informed consent, baseline data (survey and vital signs) were obtained, followed by administration of the Seva Stress Release. After the intervention, vital signs were obtained, and patients completed 2 additional surveys. After Seva, patient stress, fatigue, pain, heart rate, and respirations were significantly decreased (P = .000). Sixty-six percent of participants experienced symptom relief for at least 1 to 4 hours. Qualitative findings also indicated that patients reported better sleep and mental clarity after the intervention. The Seva protocol could be taught to nurses and be used as an independent intervention for patients experiencing adverse effects of cancer treatment, to promote comfort and reduce stress and fatigue.
C1 [Sand-Jecklin, Kari] West Virginia Univ, Sch Nursing, POB 9640 HSS, Morgantown, WV 26506 USA.
   [Reiser, Victoria] Univ Pittsburgh, Sch Nursing, Pittsburgh, PA 15261 USA.
C3 West Virginia University; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh
RP Sand-Jecklin, K (corresponding author), West Virginia Univ, Sch Nursing, POB 9640 HSS, Morgantown, WV 26506 USA.
EM ksandjecklin@hsc.wvu.edu
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NR 24
TC 2
Z9 3
U1 1
U2 25
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 1522-2179
EI 1539-0705
J9 J HOSP PALLIAT NURS
JI J. Hosp. Palliat. Nurs.
PD DEC 15
PY 2018
VL 20
IS 6
BP 521
EP 528
DI 10.1097/NJH.0000000000000484
PG 8
WC Nursing
SC Nursing
GA HA7AM
UT WOS:000450433100005
PM 30379796
DA 2026-01-16
ER

PT J
AU Abbasi, J
AF Abbasi, Jennifer
TI Can Acupuncture Keep Women on Their Breast Cancer Drugs?
SO JAMA
LA English
DT Journal Article
NR 0
TC 0
SN 1538-359
EI 
J9 JAMA
PD AUG 10
PY 2018
VL 320
IS 8
BP 744
EP 746
DI 10.1001/jama.2018.11068
PG 2
WC Acupuncture Therapy; Aromatase Inhibitors; adverse effects; Breast Neoplasms; drug therapy; Female; Humans; Medication Adherence; Pain; chemically induced; Pain Management; methods
UT PubMed:30090939
PM 30090939
DA 2018-08-10
ER

PT J
AU Cheon, S
   Lee, H
AF Cheon, Soyeon
   Lee, Hyangsook
TI Correspondence regarding Anshasi and Ahmad's "an assessment of methodological
SO Complementary therapies in clinical practice
LA English
DT Letter
DE Acupoint injection; Acupuncture; Cancer; Pharmacopuncture
C1 Acupuncture and Meridian Science Research Centre, College of Korean Medicine, Kyung Hee University, Seoul, 02447, South Korea
   Department of Public Health,College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
   Acupuncture and Meridian Science Research Centre, College of Korean Medicine, Kyung Hee University, Seoul, 02447, South Korea.
EM rc633@khu.ac.kr
NR 0
TC 0
SN 1873-694
EI 
J9 Complement Ther Clin Pract
PD NOV 7
PY 2018
VL 33
IS 
BP 138
EP 138
DI 10.1016/j.ctcp.2018.09.008
PG 0
WC Acupuncture Therapy; Cancer Pain; Humans
UT PubMed:30396611
PM 30396611
DA 2018-11-07
ER

PT J
AU Hershman, DL
   Unger, JM
   Crew, K
AF Hershman, Dawn L
   Unger, Joseph M
   Crew, Katherine
TI Acupuncture for Aromatase Inhibitor-Related Joint Pain Among Breast Cancer
SO JAMA
LA English
DT Letter
C1 Columbia University Medical Center, New York, New York.
   Fred Hutchinson Cancer Research Center, Seattle, Washington.
   Columbia University Medical Center, New York, New York.
NR 0
TC 0
SN 1538-359
EI 
J9 JAMA
PD DEC 5
PY 2018
VL 320
IS 21
BP 2270
EP 2271
DI 10.1001/jama.2018.16744
PG 1
WC Acupuncture Therapy; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Humans; Personality
UT PubMed:30512095
PM 30512095
DA 2018-12-05
ER

PT J
AU Hou, S
   Huh, B
   Kim, HK
   Kim, KH
   Abdi, S
AF Hou, Saiyun
   Huh, Billy
   Kim, Hee Kee
   Kim, Kyung-Hoon
   Abdi, Salahadin
TI Treatment of Chemotherapy-Induced Peripheral Neuropathy: Systematic Review and Recommendations
SO PAIN PHYSICIAN
LA English
DT Review
DE Chemotherapy-induced neuropathy; peripheral neuropathy; chemotherapy-tumor; neuropathic pain; chronic pain; toxicology; treatment; reduction of pain; level of evidence
ID evidence-based guideline; quality-of-life; induced polyneuropathy; double-blind; scrambler therapy; american academy; controlled-trial; pilot trial; pain; acupuncture
AB Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a commonly encountered disease entity following chemotherapy for cancer treatment. Although only duloxetine is recommended by the American Society of Clinical Oncology (ASCO) for the treatment of CIPN in 2014, the evidence of the clinical outcome for new pharmaceutic therapies and non-pharmaceutic treatments has not been clearly determined. Objective: To provide a comprehensive review and evidence-based recommendations on the treatment of CIPN. Study Design: A systematic review of each treatment regimen in patients with CIPN. Methods: The literature on the treatment of CIPN published from 1990 to 2017 was searched and reviewed. The 2011 American Academy of Neurology Clinical Practice Guidelines Process Manual was used to grade the evidence and risk of bias. We reviewed and updated the recommendations of the ASCO in 2014, and evaluated new approaches for treating CIPN. Results: A total of 26 treatment options in 35 studies were identified. Among these, 7 successful RCTs, 6 failed RCTs, 18 prospective studies, and 4 retrospective studies were included. The included studies examined not only pharmacologic therapy but also other modalities, including laser therapy, scrambler therapy, magnetic field therapy and acupuncture, etc. Most of the included studies had small sample sizes, and short follow-up periods. Primary outcome measures were highly variable across the included studies. No studies were prematurely closed owing to its adverse effects. Limitations: The limitations of this systematic review included relatively poor homogeneous, with variations in timing of treatment, primary outcomes, and chemotherapeutic agents used. Conclusion: The evidence is considered of moderate benefit for duloxetine. Photobiomodulation, known as low level laser therapy, is considered of moderate benefit based on the evidence review. Evidence did not support the use of lamotrigine and topical KA (4% ketamine and 2% amitriptyline). The evidence for tricyclic antidepressants was inconclusive as amitriptyline showed no benefit but nortriptyline had insufficient evidence. Further research on CIPN treatment is needed with larger sample sizes, long-term follow-up, standardized outcome measurements, and standardized treatment timing.
C1 [Hou, Saiyun; Huh, Billy; Kim, Hee Kee; Abdi, Salahadin] Univ Texas MD Anderson Canc Ctr, Dept Pain Med, 1400 Holcombe Blvd,Unit 0409, Houston, TX 77030 USA.
   [Kim, Kyung-Hoon] Pusan Natl Univ, Pusan, South Korea.
C3 University of Texas System; UTMD Anderson Cancer Center; Pusan National University
RP Abdi, S (corresponding author), Univ Texas MD Anderson Canc Ctr, Dept Pain Med, 1400 Holcombe Blvd,Unit 0409, Houston, TX 77030 USA.
EM sabdi@mdanderson.org
FU Helen Buchanan and Stanley Joseph Seeger Endowment at The University of Texas MD Anderson Cancer Center
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NR 70
TC 103
Z9 122
U1 0
U2 19
PU AM SOC INTERVENTIONAL PAIN PHYSICIANS
PI PADUCAH
PA 81 LAKEVIEW DR, PADUCAH, KY 42001 USA
SN 1533-3159
EI 
J9 PAIN PHYSICIAN
JI Pain Physician
PD NOV-DEC 15
PY 2018
VL 21
IS 6
BP 571
EP 592
DI 
PG 22
WC Anesthesiology; Clinical Neurology
SC Anesthesiology; Neurosciences & Neurology
GA HC2OC
UT WOS:000451640600015
PM 30508986
DA 2026-01-16
ER

PT J
AU Garcia, MK
   Cohen, L
   Spano, M
   Spelman, A
   Hashmi, Y
   Chaoul, A
   Wei, Q
   Lopez, G
AF Garcia, M. Kay
   Cohen, Lorenzo
   Spano, Michael
   Spelman, Amy
   Hashmi, Yousra
   Chaoul, Alejandro
   Wei, Qi
   Lopez, Gabriel
TI Inpatient Acupuncture at a Major Cancer Center
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE cancer; oncology; integrative medicine; acupuncture; inpatient
ID complementary therapy; oncology; model; pain
AB Background: Use of complementary and integrative therapies is increasing among cancer patients, but data regarding the impact treatments such as acupuncture have in an inpatient oncology setting are limited. Methods: Patients who received acupuncture in an inpatient hospital environment between December 2014 and December 2015 were asked to complete a modified Edmonton Symptom Assessment Scale (ESAS; 0-10 scale) before and after each visit. Pre- and post-treatment scores were examined for each symptom using paired t tests. Results: A total of 172 inpatients were treated with acupuncture in their hospital beds (257 visits). Thirty percent (n = 51) received at least one additional follow-up treatment (mean visits/patient = 1.5). Completion rate of the modified ESAS after acupuncture was 42%. The most common reasons for not completing the post-treatment ESAS were patient too drowsy or patient fell asleep (72%). For patients who reported a baseline symptom score 1, the greatest improvements (mean change +/- SD) after acupuncture on the initial visit were found for pain (-1.8 +/- 2.2; n = 69; P < .0001), nausea (-1.2 +/- 1.9; n = 30; P < .001), anxiety (-0.8 +/- 1.8; n = 36; P = .01), drowsiness (-0.6 +/- 1.8; n = 57; P = .02), and fatigue (-0.4 +/- 1.1; n = 67; P = .008). For patients who received at least one follow-up visit, significant improvement from baseline was found for sleep disturbance (-2.5 +/- 4.4; n = 17; P = .03), anxiety (-2.4 +/- 1.7; n = 9; P = .002), pain (-2.3 +/- 2.7; n = 20; P = .001), and drowsiness (-2.0 +/- 2.6; n = 16; P = .008). Conclusions: Patients who received inpatient acupuncture at a major cancer center experienced significant improvement after treatment for pain, sleep disturbance, anxiety, drowsiness, nausea, and fatigue.
C1 [Garcia, M. Kay; Cohen, Lorenzo; Spano, Michael; Spelman, Amy; Hashmi, Yousra; Chaoul, Alejandro; Wei, Qi; Lopez, Gabriel] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA.
C3 University of Texas System; UTMD Anderson Cancer Center
RP Garcia, MK (corresponding author), Univ Texas MD Anderson Canc Ctr, Dept Palliat Care Rehabil & Integrat Med, 1515 Holcombe Blvd,Unit 0462, Houston, TX 77030 USA.
EM kaygarcia@mdanderson.org
FU Duncan Family Institute; University of Texas M.D. Anderson Cancer Center; National Institutes of Health [P30 CA016672]
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NR 18
TC 23
Z9 26
U1 0
U2 10
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD MAR 15
PY 2018
VL 17
IS 1
BP 148
EP 152
DI 10.1177/1534735416685403
PG 5
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA FW2TE
UT WOS:000425156600017
PM 28050924
DA 2026-01-16
ER

PT J
AU Shafto, K
   Gouda, S
   Catrine, K
   Brown, ML
AF Shafto, Kate
   Gouda, Suzanne
   Catrine, Kris
   Brown, Melanie L.
TI Integrative Approaches in Pediatric Palliative Care
SO CHILDREN-BASEL
LA English
DT Article
DE pediatrics; palliative care; integrative medicine; symptom management; mind-body medicine; pain management; acupuncture; yoga
ID heart-rate-variability; controlled-trial; alternative medicine; nerve-stimulation; pain management; cancer-patients; mental-health; acupuncture; complementary; children
AB Pediatric palliative care is a field which focuses on caring for and treating the symptoms and distress typically associated with life-limiting illness. Integrative medicine is supported by evidence and aims to heal the whole person, including all aspects of one's lifestyle. Therapies offered by integrative medicine often empower patients and families, allowing for a sense of control. This review addresses the merging of integrative medicine philosophy and modalities with the care given to children with life-limiting illness. We review an introduction to integrative medicine, trends in its incorporation in the healthcare setting, application to patients receiving palliative care and the management of specific symptoms. A case study is offered to illustrate these principles.
C1 [Shafto, Kate] Univ Minnesota, Dept Internal Med & Pediat, Minneapolis, MN 55455 USA.
   [Gouda, Suzanne] Univ Chicago, Dept Pediat, Chicago, IL 60637 USA.
   [Catrine, Kris; Brown, Melanie L.] Childrens Hosp & Clin Minnesota, Dept Pain Med Palliat Care & Integrat Med, Minneapolis, MN 55404 USA.
   [Brown, Melanie L.] Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
C3 University of Minnesota System; University of Minnesota Twin Cities; University of Chicago; Children's Hospitals & Clinics of Minnesota; University of Minnesota System; University of Minnesota Twin Cities
RP Brown, ML (corresponding author), Childrens Hosp & Clin Minnesota, Dept Pain Med Palliat Care & Integrat Med, Minneapolis, MN 55404 USA.; Brown, ML (corresponding author), Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
EM kshafto@umn.edu; suzanne.gouda@uchospitals.edu; kris.catrine@childrensmn.org; melanie.brown@childrensmn.org
FU Coleman Foundation; Oberweiler Foundation; Patient-Centered Outcomes Research Institute
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NR 61
TC 7
Z9 9
U1 1
U2 16
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 
EI 2227-9067
J9 CHILDREN-BASEL
JI Children-Basel
PD JUN 15
PY 2018
VL 5
IS 6
BP 
EP 
DI 10.3390/children5060075
PG 12
WC Pediatrics
SC Pediatrics
GA GK6DQ
UT WOS:000436273300012
PM 29899281
DA 2026-01-16
ER

PT J
AU Armstrong, K
   Lanni, T Jr
   Anderson, MM
   Patricolo, GE
AF Armstrong, Karen
   Lanni, Thomas Jr
   Anderson, Maureen M
   Patricolo, Gail Elliott
TI Integrative medicine and the oncology patient: options and benefits.
SO Supportive care in cancer : official journal of the Multinational Association of
LA English
DT Journal Article
DE Acupuncture; Cancer; Integrative medicine; Naturopathic oncology; Oncology massage; Oncology patients
AB Cancer is a major public health problem, and cancer patients and survivors face  many physical and emotional challenges after the initial diagnosis, through  treatment, and in the post-treatment period. Different integrative medicine (IM)  modalities can be used to mitigate some of the physical issues that originate  from the cancer itself or the treatment and to promote well-being and emotional  health. Here, we discuss how an IM Department can function in a hospital system,  particularly with regard to oncology patients, the modalities appropriate for  oncology patients, how these modalities can benefit this patient population, and  the role of IM in cancer survivorship. A dedicated IM Department that works with  oncologists provides support and care for the whole person. These different  modalities work together to reduce pain, anxiety, and chemotherapy-induced nausea  and peripheral neuropathy, while promoting immune function and improving sleep,  range of motion, and an overall sense of well-being. However, each modality has  different contraindications for the oncology patient, and proper training is  required for safe and effective care. We illustrate how IM can be a valuable  component of the care of the oncology patient.
C1 Integrative Medicine, Beaumont Health, 3577 W. Thirteen Mile Road, Royal Oak, MI, 48073, USA.
   Oncology, Medicine, and Imaging, Beaumont Cancer Institute, Beaumont Health, Royal Oak, MI, 48073, USA.
   Integrative Medicine, Beaumont Health, 3577 W. Thirteen Mile Road, Royal Oak, MI, 48073, USA.
   Integrative Medicine, Beaumont Health, 3577 W. Thirteen Mile Road, Royal Oak, MI, 48073, USA. gail.elliottpatricolo@beaumont.org.
NR 0
TC 0
SN 1433-733
EI 
J9 Support Care Cancer
PD FEB 6
PY 2018
VL 26
IS 7
BP 2267
EP 2273
DI 10.1007/s00520-017-4007-y
PG 6
WC Humans; Integrative Medicine; methods; Medical Oncology; methods; Neoplasms; therapy
UT PubMed:29396594
PM 29396594
DA 2018-02-06
ER

PT J
AU Jeong, YJ
   Kwak, MA
   Seo, JC
   Park, SH
   Bong, JG
   Shin, IH
   Park, SH
AF Jeong, Young Ju
   Kwak, Min Ah
   Seo, Jung Chul
   Park, Seong Hoon
   Bong, Jin Gu
   Shin, Im Hee
   Park, Sung Hwan
TI Acupuncture for the Treatment of Taxane-Induced Peripheral Neuropathy in Breast
SO Evidence-based complementary and alternative medicine : eCAM
LA English
DT Journal Article
AB OBJECTIVES: Some chemotherapy drugs can damage the nerves and cause peripheral  neuropathy which is accompanied by severe neuropathic pain or gait impairment.  The purpose of this study was to assess the feasibility and the safety of  acupuncture for the treatment of peripheral neuropathy following chemotherapy in  Korean breast cancer patients. DESIGN: This study was a prospective single-arm  observational study using before and after measurements in breast cancer patients  presenting with taxane-induced peripheral neuropathy. SETTINGS/LOCATION: This  study was performed at East-West Medical Center at Daegu Catholic University  Hospital, Daegu, South Korea. INTERVENTIONS: Acupuncture was administered 3 times  a week for 4 consecutive weeks, for 25 ± 5 minutes at each session. OUTCOME  MEASURES: The primary outcome measure was severity of CIPN using the Neuropathic  Pain Symptom Inventory (NPSI) assessed by a self-administered questionnaire and  Nerve Conduction Study (NCS) of extremities. The secondary outcome measure was  quality of life (QoL) assessed by a self-administered questionnaire using the  36-Item Short From Health Survey (SF-36). RESULTS: Acupuncture significantly  reduced the severity of CIPN assessed by NPSI score. Four weeks after the last  treatment, the symptoms were not aggravated. According to NCS, 42.9% of  participants showed improvement of sensory neuropathy. At the end of the  treatment, SF-36 scores were significantly increased for variables including  physical functioning, role limitations due to physical health problems, social  functioning, and general health perceptions compared to those of baseline  measurement. CONCLUSIONS: Acupuncture improved symptoms of CIPN and QoL in Korean  women suffering from peripheral neuropathy after chemotherapy using taxane for  breast cancer. The effects of acupuncture lasted for at least 1 month after the  treatment.
C1 Department of Surgery, School of Medicine, Catholic University of Daegu, Daegu, Republic of Korea.
   Department of Oriental Internal Medicine, College of Oriental Medicine, Daegu Haany University, Daegu, Republic of Korea.
   Comprehensive and Integrative Medicine Institute, Daegu, Republic of Korea.
   Comprehensive and Integrative Medicine Institute, Daegu, Republic of Korea.
   Department of Surgery, Raphael Hospital, Daegu, Republic of Korea.
   Department of Medical Statistics, School of Medicine, Catholic University of Daegu, Daegu, Republic of Korea.
   Department of Surgery, School of Medicine, Catholic University of Daegu, Daegu, Republic of Korea.
NR 0
TC 0
SN 1741-428
EI 1741-427
J9 Evid Based Complement Alternat Med
PD NOV 14
PY 2018
VL 2018
IS 
BP 5367014
EP 5367014
DI 10.1155/2018/5367014
PG 0
UT PubMed:30420895
PM 30420895
DA 2018-11-14
ER

PT J
AU Lemanne, D
   Maizes, V
AF Lemanne, Dawn
   Maizes, Victoria
TI Advising Women Undergoing Treatment for Breast Cancer: A Narrative Review.
SO Journal of alternative and complementary medicine (New York, N.Y.)
LA English
DT Review
DE cancer; dietary supplements; integrative therapies; intermittent fasting; nutrition; stress management
AB A majority of women undergoing conventional treatment for breast cancer also  undertake complementary and integrative approaches. Practitioners knowledgeable  about the evidence base behind common integrative approaches can help patients  attain improved quality of life, and at times, improved survival. Evidence-based  recommendations include the following: a plant-based diet for general health  after diagnosis, and carbohydrate restriction for patients with estrogen  receptor-positive postmenopausal breast cancer may be prudent. Other dietary  recommendations include a 13-h daily overnight fast. Carefully selected patients  may choose to fast the day before and the day of chemotherapy to decrease side  effects. Specific food recommendations include avoidance or limitation of  alcohol, and liberal culinary use of cruciferous vegetables, coffee, green tea,  soy, and flaxseed. Promising supplements include diindolylmethane and melatonin.  Omega 3 fatty acids may help with bone density in patients on aromatase  inhibitors, but may increase chemotherapy resistance. Findings regarding the  usefulness of multivitamins, vitamin D, vitamin C, and vitamin E are weak and/or  mixed different exercise modalities may have different effects and thus play  different roles in breast cancer therapy. Aerobic and resistance training  combined during breast cancer chemotherapy may confer a survival benefit, while  yoga may improve outcome in lymphedema patients. Current evidence suggests that  meditation, yoga, breathing, music therapy, guided imagery, and hypnosis may  improve mood and quality of life during breast cancer treatment. Acupuncture is  useful for treating side effects of breast cancer therapies, including hot  flushes, aromatase inhibitor-induced joint pain, chemotherapy-induced peripheral  neuropathy, and vulvodynia. Vaginal moisturizers and vaginal rings supplying  low-dose estrogen can be useful in the treatment of symptoms of  estrogen-deprivation states caused by breast cancer treatments; such symptoms  include vaginal dryness, dyspareunia, and sexual dysfunction. Carbon dioxide  laser technology can rejuvenate atrophied vaginal mucosa and relieve dyspareunia,  allowing avoidance of estrogen therapy. Tertiary sexual health centers are  available for referral.
C1 1 The University of Arizona Center for Integrative Medicine , Tucson, Arizona.
   2 Oregon Integrative Oncology , Ashland, Oregon.
   3 National Institute of Integrative Medicine , Melbourne, Australia .
   1 The University of Arizona Center for Integrative Medicine , Tucson, Arizona.
NR 0
TC 0
SN 1557-770
EI 
J9 J Altern Complement Med
PD SEP 25
PY 2018
VL 24
IS 9-10
BP 902
EP 909
DI 10.1089/acm.2018.0150
PG 7
WC Acupuncture Therapy; Breast Neoplasms; therapy; Diet Therapy; Diet, Vegetarian; Dietary Supplements; Evidence-Based Medicine; Exercise; Fasting; Female; Health Knowledge, Attitudes, Practice; Humans; Integrative Oncology; Oncologists; Phytotherapy
UT PubMed:30247957
PM 30247957
DA 2018-09-25
ER

PT J
AU Anshasi, HA
   Ahmad, M
AF Anshasi, Huda A.
   Ahmad, Muayyad
TI An assessment of methodological quality of systematic reviews of acupuncture and related therapies for cancer-related pain
SO COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
LA English
DT Review
DE Acupuncture; Cancer-related pain; Patients with cancer; A systematic literature review; Meta-analyses
ID palliative care; complementary; management
AB Background and purpose: There currently exist many systematic reviews aimed at assessing acupuncture and related therapy effectiveness in cancer-related pain management. However, the methodological quality of existing systematic reviews remains unclear. The purpose of this review was to summarize and evaluate the methodological quality of these systematic reviews and meta-analyses papers. Methods: A comprehensive search on multiple databases was performed using Assessing the Methodological Quality of Systematic Reviews (AMSTAR). Results: Fourteen systematic reviews published between 2005 and 2017 were eligible for inclusion. The consensus across the included reviews was that acupuncture and related therapies alone did not have superior pain-relieving effects as compared with analgesic administration using various validated pain scales. However, as compared with analgesic administration alone, acupuncture and related therapies plus analgesics resulted in reduced cancer related-pain. Conclusion: The study findings emphasized that acupuncture and related therapies alone did not have clinically significant effects at cancer-related pain reduction as compared with analgesic administration alone. Clinicians may consider acupuncture and related therapies as adjunctive therapies for cancer-related pain management, in particular, when pain control is unsatisfactory under analgesics alone. Furthermore, the researchers should conduct the SRs and meta-analyses according to the AMSTAR and PRISMA.
C1 [Anshasi, Huda A.; Ahmad, Muayyad] Univ Jordan, Sch Nursing, Amman, Jordan.
C3 University of Jordan
RP Ahmad, M (corresponding author), Univ Jordan, Sch Nursing, Amman, Jordan.
EM anshasi_6@yahoo.com; mma4jo@yahoo.com
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NR 45
TC 11
Z9 14
U1 0
U2 16
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1744-3881
EI 1873-6947
J9 COMPLEMENT THER CLIN
JI Complement. Ther. Clin. Pract.
PD AUG 15
PY 2018
VL 32
IS 
BP 163
EP 168
DI 10.1016/j.ctcp.2018.06.013
PG 6
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GO3OX
UT WOS:000439902900029
PM 30057045
DA 2026-01-16
ER

PT J
AU Kong, C
   Han, MF
   Zhang, CP
   Zhao, ZB
   Fang, FF
   Zhang, Z
   Huang, F
   Luan, XW
   Li, B
AF Kong, Chen
   Han, Mengfei
   Zhang, Chunpeng
   Zhao, Zhibin
   Fang, Fanfu
   Zhang, Zhan
   Huang, Feng
   Luan, Xiaowei
   Li, Bai
TI Auricular point acupressure improved nausea, vomiting, diarrhea and nutritional status in gastric cancer patients receiving oral S-1. therapy
SO INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
LA English
DT Article
DE Auricular point acupressure; chemotherapy; nausea; vomiting; diarrhea; nutrition
ID low-back-pain; acupuncture; chemotherapy; fatigue; trial
AB Objective: This study explored the efficacy of auricular point acupressure (APA) on controlling gastrointestinal dysfunction and improving nutritional status in gastric cancer patients receiving oral S-1 treatments. Methods: One-hundred and ten gastric cancer patients who received oral S-1 therapy were enrolled and randomized into two sub-cohorts (1:1). In the experimental sub-cohort, specific auricular points were stimulated to control nausea, vomiting, and diarrhea, including the shenmen, cardia, stomach, sympathetic, digestive subcortex, liver, and spleen. The auricular points that were stimulated in the control cohort included the eye, wrist, toe, and external genitals. Patients wore auricular seeds for 21 days and recorded instances of nausea, vomiting, and diarrhea using the National Cancer Institute common toxicity criteria as benchmarks. Weight, height, total blood protein, and albumin levels were measured twice per patient at the start and end of the experimental course. Results: Incidence rates of nausea, vomiting, and diarrhea were similar between the two sub-cohorts (p>0.05). Patients in the experimental sub-cohort experienced lower severities and shorter durations of nausea, vomiting, and diarrhea when compared to controls (p<0.05). Additionally, patients in the experimental sub-cohort experienced less dramatic reductions in nutrition indices, including body weight, body mass index, total blood protein, and albumin levels (p<0.05). Conclusions: The data presented here indicate that APA treatment decreased the severity and duration of nausea, vomiting and diarrhea in gastric cancer patients receiving oral S-1 chemotherapy. This treatment may improve the nutritional status of treated patients. However, incidence rates of S-1 treatment-related side effects were unaltered by APA.
C1 [Kong, Chen; Han, Mengfei; Zhang, Chunpeng; Fang, Fanfu; Zhang, Zhan; Huang, Feng; Luan, Xiaowei; Li, Bai] Second Mil Med Univ, Changhai Hosp Tradit Chinese Med, Dept Rehabil Med, Shanghai, Peoples R China.
   [Zhao, Zhibin] Second Mil Med Univ, Changhai Hosp Tradit Chinese Med, Dept Acupuncture & Moxibust, Shanghai, Peoples R China.
   [Kong, Chen] New Jiangwan City Community Hlth Serv Ctr, Dept Tradit Chinese Med, Shanghai, Peoples R China.
C3 Naval Medical University; Naval Medical University
RP Li, B (corresponding author), Dept Rehabil Med, 168 Changhai Rd, Shanghai 200433, Peoples R China.
EM yadianna560@126.com
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NR 28
TC 6
Z9 6
U1 1
U2 19
PU E-CENTURY PUBLISHING CORP
PI MADISON
PA 40 WHITE OAKS LN, MADISON, WI 53711 USA
SN 1940-5901
EI 
J9 INT J CLIN EXP MED
JI Int. J. Clin. Exp. Med.
PD JUN 15
PY 2018
VL 11
IS 9
BP 9200
EP 9209
DI 
PG 10
WC Medicine, Research & Experimental
SC Research & Experimental Medicine
GA GY8AL
UT WOS:000448839700036
DA 2026-01-16
ER

PT J
AU Pan, YQ
   Yang, KH
   Shi, X
   Liang, HQ
   Shen, XP
   Wang, RJ
   Ma, L
   Cui, Q
   Yu, RZ
   Dong, Y
AF Pan, Yuanqing
   Yang, Kehu
   Shi, Xiue
   Liang, Haiqian
   Shen, Xiping
   Wang, Renjie
   Ma, Li
   Cui, Qi
   Yu, Runze
   Dong, Yi
TI Clinical Benefits of Acupuncture for the Reduction of Hormone Therapy-Related Side Effects in Breast Cancer Patients: A Systematic Review
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Review
DE acupuncture; hormone therapy-related side effects; breast cancer; systematic review; quality of life
ID randomized controlled-trial; treating hot flashes; alternative medicine; aromatase inhibitors; musculoskeletal symptoms; postmenopausal women; applied relaxation; joint symptoms; tnf-alpha; electroacupuncture
AB Importance. Acupuncture can help reduce unpleasant side effects associated with endocrine therapy for breast cancer. Nevertheless, comprehensive evaluation of current evidence from randomized controlled trials(RCTs) is lacking. Objective. To estimate the efficacy of acupuncture for the reduction of hormone therapy-related side effects in breast cancer patients. Evidence review. RCTs of acupuncture in breast cancer patients that examined reductions in hormone therapy-related side effects were retrieved from PubMed, EMBASE, Web of Science, Ovid MEDLINE, and Cochrane Library databases through April 2016. The quality of the included studies was evaluated according to the 5.2 Cochrane Handbook standards, and CONSORT and STRICTA (Revised Standards for Reporting Interventions in Clinical Trials of Acupuncture) statements. Intervention. Interventions included conventional acupuncture treatment compared with no treatment, placebo, or conventional pharmaceutical medication. Major outcome measures were the alleviation of frequency and symptoms and the presence of hormone therapy-related side effects. Findings/Results. A total of 17 RCTs, including a total of 810 breast cancer patients were examined. The methodological quality of the trials was relatively rigorous in terms of randomization, blinding, and sources of bias. Compared with control therapies, the pooled results suggested that acupuncture had moderate effects in improving stiffness. No significant differences were observed in hot flashes, fatigue, pain, gastrointestinal symptoms, Kupperman index, general well-being, physical well-being, tumor necrosis factor (TNF), and interleukin (IL). Conclusions. Acupuncture therapy appears to be potentially useful in relieving functional stiffness. However, further large-sample trials with evidence-based design are still needed to confirm these findings.
C1 [Pan, Yuanqing; Yu, Runze; Dong, Yi] Tianjin Med Coll, Tianjin, Peoples R China.
   [Pan, Yuanqing; Yang, Kehu; Shen, Xiping] Lanzhou Univ, Lanzhou, Gansu, Peoples R China.
   [Shi, Xiue] Gansu Rehabil Ctr Hosp, Lanzhou, Gansu, Peoples R China.
   [Liang, Haiqian; Wang, Renjie] Tianjin Pingjin Hosp, Tianjin, Peoples R China.
   [Ma, Li] Tianjin Med Univ, Gen Hosp, Tianjin, Peoples R China.
   [Cui, Qi] Lanzhou Univ, Affiliated Hosp 1, Lanzhou, Gansu, Peoples R China.
C3 Tianjin Medical University; Lanzhou University; Tianjin Medical University; Lanzhou University
RP Yang, KH (corresponding author), Lanzhou Univ, WHO Guide Implementat & Knowledge Convers Coopera, Sch Basic Med Sci, Evidence Based Med Ctr,Key Lab Clin Translat Res, 199 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.
EM kehuyangebm2006@126.com
CR Unknown -, 2011, EVID BASED COMPLEMEN, V0, P0
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NR 49
TC 21
Z9 26
U1 0
U2 35
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD SEP 15
PY 2018
VL 17
IS 3
BP 602
EP 618
DI 10.1177/1534735418786801
PG 17
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA GQ8BY
UT WOS:000441976400003
PM 30117343
DA 2026-01-16
ER

PT J
AU Zhang, H
   Chen, ZY
   Wu, JP
   Chen, N
   Xu, WJ
   Li, TH
   Liu, SP
AF Zhang, Heng
   Chen, Zhenyi
   Wu, Jiping
   Chen, Na
   Xu, Wenjie
   Li, Taihao
   Liu, Shupeng
TI Laser stimulating ST36 with optical fiber induce blood component changes in mice: a Raman spectroscopy study
SO JOURNAL OF BIOPHOTONICS
LA English
DT Article
DE acupuncture; laser therapy; optical fiber; Raman scattering; ST36
ID cancers
AB ST36 is a commonly-used acupoint in traditional Chinese medicine (TCM) for treatment of inflammations, pains and gastrointestinal disturbs. For decades, the low power laser acupuncture has been widely applied as an alternative therapy to traditional metal needle acupuncture and achieved relatively fine therapeutic effect for ST36-related symptoms with reduction of uncomfortableness and infection risks. However its disadvantages of low penetrativity and lack of manipulation skills limit its potential performance. An optical fiber laser acupuncture introduced by the previous study combines traditional needling acupuncture and the laser stimulation together, making a stronger therapeutic effect and showing a potential value in clinical application. To evaluate its acupunctural effect on blood, mice are taken as experimental model and Raman spectroscopic technique is used to analysis the changes of blood components after stimulating on ST36. The results show that both the traditional needling acupuncture and optical fiber acupuncture could lead to some spectral changes of blood in mice. This study explores the optical fiber acupuncture's effect on blood in mice using Raman spectroscopy technique for mechanism of acupuncture therapy.
C1 [Zhang, Heng; Chen, Zhenyi; Wu, Jiping; Chen, Na; Xu, Wenjie; Liu, Shupeng] Shanghai Univ, Shanghai Inst Adv Commun & Data Sci, Joint Int Res Lab Specialty Fiber Opt & Adv Commu, Key Lab Specialty Fiber Opt & Opt Access Networks, 333 Nanchen Rd, Shanghai 200444, Peoples R China.
   [Li, Taihao] Capital Normal Univ, Beijing Adv Innovat Ctr Imaging Technol, Beijing, Peoples R China.
C3 Shanghai University; Capital Normal University
RP Liu, SP (corresponding author), Shanghai Univ, Shanghai Inst Adv Commun & Data Sci, Joint Int Res Lab Specialty Fiber Opt & Adv Commu, Key Lab Specialty Fiber Opt & Opt Access Networks, 333 Nanchen Rd, Shanghai 200444, Peoples R China.
EM liusp@shu.edu.cn
FU National Natural Science Foundation of China [61475095, 61575120]; Key Laboratory of Specialty Fiber Optics and Optical Access Networks [SKLSFO2015-06, SKLSFO2017-02]; Natural Science Foundation of China (NSFC) [61475095, 61575120, 61520106014, 61422507]
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NR 80
TC 5
Z9 6
U1 2
U2 31
PU WILEY-V C H VERLAG GMBH
PI WEINHEIM
PA POSTFACH 101161, 69451 WEINHEIM, GERMANY
SN 1864-063X
EI 1864-0648
J9 J BIOPHOTONICS
JI J. Biophotonics
PD JUN 15
PY 2018
VL 11
IS 6
BP 
EP 
DI 10.1002/jbio.201700262
PG 11
WC Biochemical Research Methods; Biophysics; Optics
SC Biochemistry & Molecular Biology; Biophysics; Optics
GA GI6VR
UT WOS:000434641700005
PM 29446873
DA 2026-01-16
ER

PT J
AU Zeng, YS
   Wang, C
   Ward, KE
   Hume, AL
AF Zeng, Yvette S.
   Wang, Connie
   Ward, Kristina E.
   Hume, Anne L.
TI Complementary and Alternative Medicine in Hospice and Palliative Care: A Systematic Review
SO JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
LA English
DT Review
DE Complementary therapy; alternative therapy; palliative care; hospice care; symptom management; review
ID quality-of-life; randomized controlled-trial; aromatherapy massage; music-therapy; cancer; pain; management; instrument; anxiety; people
AB Context. The aim of palliative care is to improve quality of life for patients with serious illnesses by treating their symptoms and adverse effects. Hospice care also aims for this for patients with a life expectancy of six months or less. When conventional therapies do not provide adequate symptom management or produce their own adverse effects, patients, families, and caregivers may prefer complementary or alternative approaches in their care. Objectives. The objectives of this study were to evaluate the available evidence on the use of complementary or alternative medicine (CAM) in hospice and palliative care and to summarize their potential benefits. Methods. A defined search strategy was used in reviewing literature from major databases. Searches were conducted using base terms and the symptom in question. Symptoms included anxiety, pain, dyspnea, cough, fatigue, insomnia, nausea, and vomiting. Studies were selected for further evaluation based on relevancy and study type. References of systematic reviews were also assessed. After evaluation using quality assessment tools, findings were summarized and the review was structured based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results. Out of 4682 studies, 17 were identified for further evaluation. Therapies included acupressure, acupuncture, aromatherapy massage, breathing, hypnotherapy, massage, meditation, music therapy, reflexology, and reiki. Many studies demonstrated a short-term benefit in symptom improvement from baseline with CAM, although a significant benefit was not found between groups. Conclusion. CAM may provide a limited short-term benefit in patients with symptom burden. Additional studies are needed to clarify the potential value of CAM in the hospice or palliative setting. (C) 2018 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.
C1 [Zeng, Yvette S.; Wang, Connie; Ward, Kristina E.; Hume, Anne L.] Univ Rhode Isl, Kingston, RI 02881 USA.
C3 University of Rhode Island
RP Hume, AL (corresponding author), Univ Rhode Isl, Coll Pharm, 7 Greenhouse Rd, Kingston, RI 02881 USA.
EM alhume@uri.edu
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NR 40
TC 61
Z9 79
U1 1
U2 105
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0885-3924
EI 1873-6513
J9 J PAIN SYMPTOM MANAG
JI J. Pain Symptom Manage.
PD NOV 15
PY 2018
VL 56
IS 5
BP 781
EP +
DI 10.1016/j.jpainsymman.2018.07.016
PG 18
WC Health Care Sciences & Services; Medicine, General & Internal; Clinical Neurology
SC Health Care Sciences & Services; General & Internal Medicine; Neurosciences & Neurology
GA GX0EG
UT WOS:000447382000016
PM 30076965
DA 2026-01-16
ER

PT J
AU Lyman, GH
   Greenlee, H
   Bohlke, K
   Bao, T
   DeMichele, AM
   Deng, GE
   Fouladbakhsh, JM
   Gil, B
   Hershman, DL
   Mansfield, S
   Mussallem, DM
   Mustian, KM
   Price, E
   Rafte, S
   Cohen, L
AF Lyman, Gary H
   Greenlee, Heather
   Bohlke, Kari
   Bao, Ting
   DeMichele, Angela M
   Deng, Gary E
   Fouladbakhsh, Judith M
   Gil, Brigitte
   Hershman, Dawn L
   Mansfield, Sami
   Mussallem, Dawn M
   Mustian, Karen M
   Price, Erin
   Rafte, Susan
   Cohen, Lorenzo
TI Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement
SO Journal of clinical oncology : official journal of the American Society of
LA English
DT Journal Article
AB Purpose The Society for Integrative Oncology (SIO) produced an evidence-based  guideline on use of integrative therapies during and after breast cancer  treatment that was determined to be relevant to the American Society of Clinical  Oncology (ASCO) membership. ASCO considered the guideline for endorsement.  Methods The SIO guideline addressed the use of integrative therapies for the  management of symptoms and adverse effects, such as anxiety and stress, mood  disorders, fatigue, quality of life, chemotherapy-induced nausea and vomiting,  lymphedema, chemotherapy-induced peripheral neuropathy, pain, and sleep  disturbance. Interventions of interest included mind and body practices, natural  products, and lifestyle modifications. SIO systematic reviews focused on  randomized controlled trials that were published from 1990 through 2015. The SIO  guideline was reviewed by ASCO content experts for clinical accuracy and by ASCO  methodologists for developmental rigor. On favorable review, an ASCO Expert Panel  was convened to review the guideline contents and recommendations. Results The  ASCO Expert Panel determined that the recommendations in the SIO  guideline-published in 2017-are clear, thorough, and based on the most relevant  scientific evidence. ASCO endorsed the guideline with a few added discussion  points. Recommendations Key recommendations include the following: Music therapy,  meditation, stress management, and yoga are recommended for anxiety/stress  reduction. Meditation, relaxation, yoga, massage, and music therapy are  recommended for depression/mood disorders. Meditation and yoga are recommended to  improve quality of life. Acupressure and acupuncture are recommended for reducing  chemotherapy-induced nausea and vomiting. Acetyl-l-carnitine is not recommended  to prevent chemotherapy-induced peripheral neuropathy because of a possibility of  harm. No strong evidence supports the use of ingested dietary supplements to  manage breast cancer treatment-related adverse effects. Additional information is  available at: www.asco.org/supportive-care-guidelines .
C1 Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
   Gary H. Lyman and Heather Greenlee, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA
   Kari Bohlke, American Society of ClinicalOncology, Alexandria, VA
   Ting Bao and Gary E. Deng, Memorial Sloan KetteringCancer Center
   Dawn L. Hershman, Columbia University Medical Center, New York;Karen M. Mustian, University of Rochester Medical Center, Rochester, NY
   AngelaM. DeMichele, Perelman School of Medicine, University of Pennsylvania,Philadelphia, PA
   Judith M. Fouladbakhsh, Oakland University, Rochester, MI;Brigitte Gil, Lahey Hospital and Medical Center, Burlington, MA
   Sami Mansfield,Cancer Wellness for Life, Shawnee, KS
   Sarah Cannon Cancer Institute, KansasCity, MO
   Dawn M. Mussallem, The Mayo Clinic, Jacksonville, FL
   Erin Price, SmithCenter for Healing and the Arts, Washington, DC
   Susan Rafte, Houston, TX
   andLorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX.
NR 0
TC 0
SN 1527-775
EI 
J9 J Clin Oncol
PD JUN 12
PY 2018
VL 36
IS 25
BP 2647
EP 2655
DI 10.1200/JCO.2018.79.2721
PG 8
WC Breast Neoplasms; therapy; Female; Humans; Integrative Oncology; methods
UT PubMed:29889605
PM 29889605
DA 2018-06-12
ER

PT J
AU Zhao, HY
   Liu, LY
   Cai, J
   Cui, YJ
   Xing, GG
AF Zhao, Hong-Yan
   Liu, Ling-Yu
   Cai, Jie
   Cui, Yan-Jun
   Xing, Guo-Gang
TI Electroacupuncture Treatment Alleviates the Remifentanil-Induced Hyperalgesia by Regulating the Activities of the Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats
SO NEURAL PLASTICITY
LA English
DT Article
ID local-field potentials; gamma-band activity; spinal dorsal-horn; bone cancer pain; neuropathic pain; brain; oscillations; cord; contributes; morphine
AB Mechanisms underlying remifentanil- (RF-) induced hyperalgesia, a phenomenon that is generally named as opioid-induced hyperalgesia (OIH), still remain elusive. The ventral posterior lateral nucleus (VPL) of the thalamus, a key relay station for the transmission of nociceptive information to the cerebral cortex, is activated by RF infusion. Electroacupuncture (EA) is an effective method for the treatment of pain. This study aimed to explore the role of VPL in the development of OIH and the effect of EA treatment on OIH in rats. RF was administered to rats via the tail vein for OIH induction. Paw withdrawal threshold (PWT) in response to mechanical stimuli and paw withdrawal latency (PWL) to thermal stimulation were tested in rats for the assessment of mechanical allodynia and thermal hyperalgesia, respectively. Spontaneous neuronal activity and local field potential (LFP) in VPL were recorded in freely moving rats using the in vivo multichannel recording technique. EA at 2 Hz frequency (pulse width 0.6 ms, 1-3 mA) was applied to the bilateral acupoints "Zusanli" (ST.36) and "Sanyinjiao" (SP.6) in rats. The results showed that both the PWT and PWL were significantly decreased after RF infusion to rats. Meanwhile, both the spontaneous neuronal firing rate and the theta band oscillation in VPL LFP were increased on day 3 post-RF infusion, indicating that the VPL may promote the development of RF- induced hyperalgesia by regulating the pain-related cortical activity. Moreover, 2 Hz-EA reversed the RF- induced decrease both in PWT and PWL of rats and also abrogated the RF-induced augmentation of the spontaneous neuronal activity and the power spectral density (PSD) of the theta band oscillation in VPL LFP. These results suggested that 2 Hz-EA attenuates the remifentanil- induced hyperalgesia via reducing the excitability of VPL neurons and the low-frequency (theta band) oscillation in VPL LFP.
C1 [Zhao, Hong-Yan; Liu, Ling-Yu; Cai, Jie; Xing, Guo-Gang] Peking Univ, Neurosci Res Inst, Sch Basic Med Sci, Beijing 100083, Peoples R China.
   [Zhao, Hong-Yan; Liu, Ling-Yu; Cai, Jie; Xing, Guo-Gang] Peking Univ, Dept Neurobiol, Sch Basic Med Sci, Beijing 100083, Peoples R China.
   [Cui, Yan-Jun] Peking Univ Hosp, Dept Internal Med, Beijing 100871, Peoples R China.
   [Xing, Guo-Gang] Xinxiang Med Univ, Affiliated Hosp 2, Xinxiang 453002, Henan, Peoples R China.
   [Xing, Guo-Gang] Minist Educ, Key Lab Neurosci, Natl Hlth & Family Planning Commiss, Beijing 100083, Peoples R China.
C3 Peking University; Peking University; Peking University; Henan Medical University
RP Xing, GG (corresponding author), Peking Univ, Neurosci Res Inst, Sch Basic Med Sci, Beijing 100083, Peoples R China.; Xing, GG (corresponding author), Peking Univ, Dept Neurobiol, Sch Basic Med Sci, Beijing 100083, Peoples R China.; Cui, YJ (corresponding author), Peking Univ Hosp, Dept Internal Med, Beijing 100871, Peoples R China.; Xing, GG (corresponding author), Xinxiang Med Univ, Affiliated Hosp 2, Xinxiang 453002, Henan, Peoples R China.; Xing, GG (corresponding author), Minist Educ, Key Lab Neurosci, Natl Hlth & Family Planning Commiss, Beijing 100083, Peoples R China.
EM cyj@pku.edu.cn; ggxing@bjmu.edu.cn
FU National Natural Science Foundation of China [81671085, 81371237, 61527815]; National Basic Research Program of China (973 Program) [2013CB531905]; Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences [ZZ04004]
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NR 83
TC 17
Z9 18
U1 0
U2 8
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 2090-5904
EI 1687-5443
J9 NEURAL PLAST
JI Neural. Plast.
PD JUN 15
PY 2018
VL 2018
IS 
BP 
EP 
DI 10.1155/2018/6109723
PG 15
WC Neurosciences
SC Neurosciences & Neurology
GA HB6TL
UT WOS:000451205000001
PM 30534151
DA 2026-01-16
ER

PT J
AU Serçe, S
   Ovayolu, Ö
   Pirbudak, L
   Ovayolu, N
AF Serçe, Sibel
   Ovayolu, Özlem
   Pirbudak, Lütfiye
   Ovayolu, Nimet
TI The Effect of Acupressure on Pain in Cancer Patients With Bone Metastasis: A
SO Integrative cancer therapies
LA English
DT Journal Article
DE acupressure; cancer; metastasis; nursing; pain; radiotherapy
AB BACKGROUND: Pain is a serious and common problem in bone metastases. For this  purpose, complementary and supportive practices are also applied along with  medical treatment. This study was conducted for the purpose of evaluating the  effect of acupressure on pain in cancer patients with bone metastasis. METHODS:  The study was conducted in a nonrandomized controlled trial with patients who  applied to the radiotherapy unit of an oncology hospital. The data of the study  were collected by using a questionnaire and the Visual Analog Scale. A total of 8  acupressure sessions, which lasted for approximately 10 minutes each (with  warming and acupressure periods), was applied to the intervention group. The data  were analyzed by using χ(2) test, paired t test, and Pearson's correlation  coefficient. RESULTS: It was determined that the pain mean score of the  intervention group was 7.6 ± 1.9 before the acupressure and decreased to 6.8 ±  1.9 after the acupressure and this result was statistically significant. On the  other hand, no significant difference was determined in the pain mean score of  the control group. CONCLUSIONS: Acupressure is applicable for cancer patients  with bone metastasis by nursing staff after receiving brief training and may make  a difference in relieving pain of the patients. Further well-designed trials  should be conducted.
C1 1 Gaziantep University Hospital.
   2 Department of Nursing, Faculty of Health Science, Gaziantep University.
   3 School of Medicine, Gaziantep University.
   4 Department of Nursing, Faculty of Health Science, Gaziantep University.
NR 0
TC 0
SN 1552-695
EI 1534-735
J9 Integr Cancer Ther
PD APR 14
PY 2018
VL 17
IS 3
BP 728
EP 736
DI 10.1177/1534735418769153
PG 8
WC Acupressure; methods; Adult; Bone Neoplasms; complications; Cancer Pain; etiology; Female; Humans; Male; Middle Aged; Pain Management; methods; Surveys and Questionnaires; Visual Analog Scale; Young Adult
UT PubMed:29649905
PM 29649905
DA 2018-04-14
ER

PT J
AU Zhang, Y
   Li, A
   Xin, J
   Ren, K
   Berman, BM
   Lao, L
   Zhang, RX
AF Zhang, Y.
   Li, A.
   Xin, J.
   Ren, K.
   Berman, B. M.
   Lao, L.
   Zhang, R-X
TI Electroacupuncture alleviates chemotherapy-induced pain through inhibiting phosphorylation of spinal CaMKII in rats
SO EUROPEAN JOURNAL OF PAIN
LA English
DT Article
ID 5-ht1a receptor agonist; induced peripheral neuropathy; fos protein expression; kinase-ii; brain-stem; mechanical allodynia; inflammatory pain; noxious stimulus; serotonin 5-ht1a; paclitaxel
AB BackgroundCurrent medical treatments for chemotherapy-induced pain (CIP) are either ineffective or have adverse side effects. Acupuncture may alleviate CIP, but its effectiveness against this condition has not been studied. Paclitaxel causes neuropathic pain in cancer patients. MethodsWe evaluated the effects of electroacupuncture (EA) on paclitaxel-induced CIP in a rat model. Paclitaxel (2mg/kg) or vehicle was injected (i.p.) on alternate days of 0-6. The resulting pain was treated with 10Hz/2mA/0.4ms pulse EA for 30min at the equivalent of human acupoint GB30 (Huantiao) once every other day between days 14 and 26. For sham control, EA needles were inserted into GB30 without stimulation. Von Frey filaments with bending forces of 2-8g and 15g were used to assess mechanical allodynia and hyperalgesia, respectively, on day 13 and once every other day between 14-26days and then for 2-3weeks after EA treatment. ResultsCompared to sham control, EA significantly alleviated paclitaxel-induced mechanical allodynia and hyperalgesia, as shown by less frequent withdrawal responses to the filaments. The alleviation of allodynia/hyperalgesia lasted up to 3weeks after the EA treatment. EA significantly inhibited phosphorylation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in the spinal cord. KN-93, a selective inhibitor of p-CaMKII, inhibited mechanical allodynia/hyperalgesia and p-CaMKII. 5-HT1A receptor antagonist blocked EA inhibition of allodynia/hyperalgesia and p-CaMKII. ConclusionsElectroacupuncture activates 5-HT 1A receptors in the spinal cord and inhibits p-CaMKII to alleviate both allodynia and hyperalgesia. The data support acupuncture/EA as a complementary therapy for CIP. SignificanceElectroacupuncture (EA) activates spinal 5-HT1A receptors to inhibit p-CaMKII to alleviate paclitaxel-induced pain. Acupuncture/EA may be used as a complementary therapy for CIP.
C1 [Zhang, Y.] Shanxi Med Univ, Dept Physiol, Taiyuan, Shanxi, Peoples R China.
   [Li, A.; Xin, J.; Berman, B. M.; Lao, L.; Zhang, R-X] Univ Maryland, Sch Med, Ctr Integrat Med, Baltimore, MD 21201 USA.
   [Ren, K.] Univ Maryland, Sch Dent, Dept Neural & Pain Sci, Baltimore, MD 21201 USA.
C3 Shanxi Medical University; University System of Maryland; University of Maryland Baltimore; University System of Maryland; University of Maryland Baltimore
RP Zhang, RX (corresponding author), Univ Maryland, Sch Med, Ctr Integrat Med, Baltimore, MD 21201 USA.
EM Rzhang@som.umaryland.edu
FU NIH [R21 AT004113, R21 AT008467-01A1]
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NR 61
TC 31
Z9 39
U1 0
U2 25
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1090-3801
EI 1532-2149
J9 EUR J PAIN
JI Eur. J. Pain
PD APR 15
PY 2018
VL 22
IS 4
BP 679
EP 690
DI 10.1002/ejp.1132
PG 12
WC Anesthesiology; Clinical Neurology; Neurosciences
SC Anesthesiology; Neurosciences & Neurology
GA FZ4LO
UT WOS:000427563900005
PM 29034548
DA 2026-01-16
ER

PT J
AU Xie, YH
   Ma, J
   Wang, D
   Chai, XQ
   Gao, C
AF Xie, Yanhu
   Ma, Jun
   Wang, Di
   Chai, Xiaoqing
   Gao, Chen
TI Electro-acupuncture stimulation prevents remifentanil-induced postoperative by peralgesia by suppressing spinal microglia in rats
SO EXPERIMENTAL AND THERAPEUTIC MEDICINE
LA English
DT Article
DE electro-acupuncture; remifentanil; postoperative hyperalgesia; pro-inflammatory cytokines; microglia
ID opioid-induced hyperalgesia; inflammatory pain; neuropathic pain; model; acupuncture; receptors; contributes; activation; anesthesia; fentanyl
AB The aim of the present study was to assess the effect of electro-acupuncture (EA) stimulation on remifentanil-induced postoperative hyperalgesia (RIPH) and the possible involvement of spinal microglia suppression. A model of RIPH was established using adult male Sprague-Dawley rats by administration of remifentanil at 0.08 mg/kg intravenously for 60 min. The Huantiao and Yanglingquan acupoints were stimulated continuously by EA (2 Hz, similar to 1 mA) for 90 min from before paw incision to the end of remifentanil administration. Sham acupoints were stimulated by EA in the sham group. paw withdrawal threshold (PWT) and paw thermal withdrawal latency (PWL) were determined. Cluster of differentiation (CD)11b, tumor necrosis factor (TNF)-alpha, interleukin (IL)-1 beta and IL-6 levels in spinal cord samples were measured using immunohistochemistry and ELISA. PWT and PWL values were decreased following the administration of remifentanill; however, following EA, PWT and PWL, values increased compared with the sham group (P<0.05), indicating that EA alleviates remifentanil-induced RIPH. CD11b, TNF-alpha, IL-1 beta and IL-6 levels were increased following remifentanil administration and these effects were counteracted by EA (all P<0.05). In the sham group, no significant differences were observed in PWT and PWL values or CD11b, TNF-alpha, IL-beta and IL-6 levels compared with the control group, suggesting that EA was responsible for the reduction in CD11b and pro-inflammatory cytokine expression following remifentanil administration. The results of the present study demonstrated that EA at the Huantiao and Yanglingquan acupoints may reduce remifentanil-induced postoperative hyperalgesia, likely by inhibiting spinal microglia via reduction of CD11b and pro-inflammatory cytokine expression. However, these results are preliminary and require further validation.
C1 [Xie, Yanhu; Ma, Jun; Wang, Di; Chai, Xiaoqing; Gao, Chen] Anhui Med Univ, Anhui Prov Hosp, Dept Anesthesiol, 17 Lujiang Rd, Hefei 230001, Anhui, Peoples R China.
C3 Anhui Medical University
RP Chai, XQ (corresponding author), Anhui Med Univ, Anhui Prov Hosp, Dept Anesthesiol, 17 Lujiang Rd, Hefei 230001, Anhui, Peoples R China.
EM 2660747430@qq.com
FU Department of Health of Anhui Province [2012zy45]
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NR 44
TC 7
Z9 10
U1 1
U2 6
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1792-0981
EI 1792-1015
J9 EXP THER MED
JI Exp. Ther. Med.
PD JUL 15
PY 2018
VL 16
IS 1
BP 353
EP 359
DI 10.3892/etm.2018.6161
PG 7
WC Medicine, Research & Experimental
SC Research & Experimental Medicine
GA GL4IZ
UT WOS:000437115500050
PM 29896261
DA 2026-01-16
ER

PT J
AU Hershman, DL
   Unger, JM
   Crew, K
AF Hershman, Dawn L.
   Unger, Joseph M.
   Crew, Katherine
TI Acupuncture for Aromatase Inhibitor-Related Joint Pain Among Breast Cancer Patients Reply
SO JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
LA English
DT Letter
C1 [Hershman, Dawn L.; Crew, Katherine] Columbia Univ, Med Ctr, 161 Ft Washington Ave,10-1068, New York, NY 10032 USA.
   [Unger, Joseph M.] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
C3 Columbia University; Fred Hutchinson Cancer Center
RP Hershman, DL (corresponding author), Columbia Univ, Med Ctr, 161 Ft Washington Ave,10-1068, New York, NY 10032 USA.
EM dlh23@cumc.columbia.edu
FU NCI NIH HHS [UG1 CA189974] Funding Source: Medline; National Cancer Institute [UG1CA189974] Funding Source: NIH RePORTER
CR Farrar JT, 2001, PAIN, V94, P149, DOI 10.1016/S0304-3959(01)00349-9
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NR 6
TC 10
Z9 10
U1 0
U2 16
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 0098-7484
EI 1538-3598
J9 JAMA-J AM MED ASSOC
JI JAMA-J. Am. Med. Assoc.
PD DEC 4
PY 2018
VL 320
IS 21
BP 2270
EP 2271
DI 10.1001/jama.2018.16744
PG 2
WC Medicine, General & Internal
SC General & Internal Medicine
GA HD4MB
UT WOS:000452500600023
PM 30512095
DA 2026-01-16
ER

PT J
AU Deng, G
   Giralt, S
   Chung, DJ
   Landau, H
   Siman, J
   Search, B
   Coleton, M
   Vertosick, E
   Shapiro, N
   Chien, C
   Wang, XS
   Cassileth, B
   Mao, JJ
AF Deng, Gary
   Giralt, Sergio
   Chung, David J.
   Landau, Heather
   Siman, Jonathan
   Search, Benjamin
   Coleton, Marci
   Vertosick, Emily
   Shapiro, Nathan
   Chien, Christine
   Wang, Xin S.
   Cassileth, Barrie
   Mao, Jun J.
TI Acupuncture for reduction of symptom burden in multiple myeloma patients undergoing autologous hematopoietic stem cell transplantation: a randomized sham-controlled trial
SO SUPPORTIVE CARE IN CANCER
LA English
DT Article
DE Acupuncture; Multiple myeloma; Hematopoietic stem cell transplantation; Symptom management; Complementary therapies; Integrative medicine
ID chemotherapy-induced nausea; quality-of-life; cancer-patients; oral-surgery; efficacy; pain; electroacupuncture; distress
AB Hematopoietic stem cell transplantation (HCT) is potentially curative for a number of hematologic malignancies, but is associated with high symptom burden. We conducted a randomized sham-controlled trial (RCT) to evaluate efficacy and safety of acupuncture as an integrative treatment for managing common symptoms during HCT. Adult patients with multiple myeloma undergoing high-dose melphalan followed by autologous HCT (AHCT) were randomized to receive either true or sham acupuncture once daily for 5 days starting the day after chemotherapy. Patients and clinical evaluators, but not acupuncturists, were blinded to group assignment. Symptom burden, the primary outcome was assessed with the MD Anderson Symptom Inventory (MDASI) at baseline, during transplantation, and at 15 and 30 days post transplantation. Among 60 participants, true acupuncture produced nonsignificant reductions in overall MDASI core symptom scores and symptom interference scores during transplantation (P = .4 and .3, respectively), at 15 days (P = .10 and .3), and at 30 days posttransplantation (P = .2 and .4) relative to sham. However, true acupuncture was significantly more efficacious in reducing nausea, lack of appetite, and drowsiness at 15 days (P = .042, .025, and .010, respectively). Patients receiving sham acupuncture were more likely to increase pain medication use posttransplantation (odds ratio 5.31, P = .017). Acupuncture was well tolerated with few attributable adverse events. True acupuncture may prevent escalation of symptoms including nausea, lack of appetite, and drowsiness experienced by patients undergoing AHCT, and reduce the use of pain medications. These findings need to be confirmed in a future definitive study. NCT01811862.
C1 [Deng, Gary; Siman, Jonathan; Search, Benjamin; Coleton, Marci; Cassileth, Barrie; Mao, Jun J.] Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1429 First Ave, New York, NY 10021 USA.
   [Giralt, Sergio; Chung, David J.; Landau, Heather] Mem Sloan Kettering Canc Ctr, Bone Marrow Transplantat Serv, 1275 York Ave, New York, NY 10021 USA.
   [Vertosick, Emily; Shapiro, Nathan; Chien, Christine] Mem Sloan Kettering Canc Ctr, Hlth Outcomes Res Grp, 1275 York Ave, New York, NY 10021 USA.
   [Wang, Xin S.] Univ Texas MD Anderson Canc Ctr, Dept Symptom Res, Houston, TX 77030 USA.
C3 Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; University of Texas System; UTMD Anderson Cancer Center
RP Deng, G (corresponding author), Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1429 First Ave, New York, NY 10021 USA.
EM dengg@mskcc.org
FU Gateway for Cancer Research; MSK Integrative Medicine and Translational Research Grant; National Institutes of Health/National Cancer Institute (NIH/NCI) Cancer Center Support Grant [P30 CA008748]; AC Israel Foundation; Byrne Fund; National Cancer Institute [P30CA008748] Funding Source: NIH RePORTER
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NR 28
TC 27
Z9 31
U1 2
U2 23
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0941-4355
EI 1433-7339
J9 SUPPORT CARE CANCER
JI Support. Care Cancer
PD FEB 15
PY 2018
VL 26
IS 2
BP 657
EP 665
DI 10.1007/s00520-017-3881-7
PG 9
WC Oncology; Health Care Sciences & Services; Rehabilitation
SC Oncology; Health Care Sciences & Services; Rehabilitation
GA FR8XS
UT WOS:000419358600039
PM 28920142
DA 2026-01-16
ER

PT J
AU Jeong, YJ
   Kwak, MA
   Seo, JC
   Park, SH
   Bong, JG
   Shin, IH
   Parkwo, SH
AF Jeong, Young Ju
   Kwak, Min Ah
   Seo, Jung Chul
   Park, Seong Hoon
   Bong, Jin Gu
   Shin, Im Hee
   Parkwo, Sung Hwan
TI Acupuncture for the Treatment of Taxane-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Trial
SO EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
LA English
DT Article
ID management; efficacy; oncology; pain
AB Objectives. Some chemotherapy drugs can damage the nerves and cause peripheral neuropathy which is accompanied by severe neuropathic pain or gait impairment. The purpose of this study was to assess the feasibility and the safety of acupuncture for the treatment of peripheral neuropathy following chemotherapy in Korean breast cancer patients. Design. This study was a prospective single-arm observational study using before and after measurements in breast cancer patients presenting with taxane-induced peripheral neuropathy. Settings/Location. This study was performed at East-West Medical Center at Daegu Catholic University Hospital, Daegu, South Korea. Interventions. Acupuncture was administered 3 times a week for 4 consecutive weeks, for 25 +/- 5 minutes at each session. Outcome Measures. The primary outcome measure was severity of CIPN using the Neuropathic Pain Symptom Inventory (NPSI) assessed by a self-administered questionnaire and Nerve Conduction Study (NCS) of extremities. The secondary outcome measure was quality of life (QoL) assessed by a self-administered questionnaire using the 36-Item Short From Health Survey (SF-36). Results. Acupuncture significantly reduced the severity of CIPN assessed by NPSI score. Four weeks after the last treatment, the symptoms were not aggravated. According to NCS, 42.9% of participants showed improvement of sensory neuropathy. At the end of the treatment, SF-36 scores were significantly increased for variables including physical functioning, role limitations due to physical health problems, social functioning, and general health perceptions compared to those of baseline measurement. Conclusions. Acupuncture improved symptoms of CIPN and QoL in Korean women suffering from peripheral neuropathy after chemotherapy using taxane for breast cancer. The effects of acupuncture lasted for at least 1 month after the treatment.
C1 [Jeong, Young Ju; Parkwo, Sung Hwan] Catholic Univ Daegu, Sch Med, Dept Surg, Daegu, South Korea.
   [Kwak, Min Ah] Daegu Haany Univ, Coll Oriental Med, Dept Oriental Internal Med, Daegu, South Korea.
   [Seo, Jung Chul; Park, Seong Hoon] Comprehens & Integrat Med Inst, Daegu, South Korea.
   [Bong, Jin Gu] Raphael Hosp, Dept Surg, Daegu, South Korea.
   [Shin, Im Hee] Catholic Univ Daegu, Sch Med, Dept Med Stat, Daegu, South Korea.
C3 Catholic University of Daegu; Daegu Haany University; Catholic University of Daegu
RP Park, SH (corresponding author), Comprehens & Integrat Med Inst, Daegu, South Korea.
EM shwpark@cu.ac.kr
FU Ministry of Health and Welfare, Republic of Korea [090-091-3000-3038-301-320-01]
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NR 34
TC 21
Z9 25
U1 0
U2 13
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1741-427X
EI 1741-4288
J9 EVID-BASED COMPL ALT
JI Evid.-based Complement Altern. Med.
PD JUN 15
PY 2018
VL 2018
IS 
BP 
EP 
DI 10.1155/2018/5367014
PG 11
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GZ3WW
UT WOS:000449319600001
PM 30420895
DA 2026-01-16
ER

PT J
AU Teoh, AYB
   Chong, CCN
   Leung, WW
   Chan, SKC
   Tse, YK
   Ng, EKW
   Lai, PBS
   Wu, JCY
   Lau, JYW
AF Teoh, Anthony Yuen Bun
   Chong, Charing Ching Ning
   Leung, Wing Wa
   Chan, Simon Kin Cheong
   Tse, Yee Kit
   Ng, Enders Kwok Wai
   Lai, Paul Bo San
   Wu, Justin Che Yuen
   Lau, James Yun Wong
TI Electroacupuncture-reduced sedative and analgesic requirements for diagnostic EUS: a prospective, randomized, double-blinded, sham-controlled study
SO GASTROINTESTINAL ENDOSCOPY
LA English
DT Article
ID controlled-trial; gi endoscopy; acupuncture; disorders; cancer; gastroscopy; colonoscopy
AB Background and Aims: The role of electroacupuncture (EA) in reducing sedative and analgesic requirements during EUS is uncertain. The aim of this study was to investigate the efficacy of EA in reducing procedure-related pain and discomfort during EUS. Methods: This was a double-blinded randomized controlled study conducted between March 2014 and July 2016. Consecutive patients who were scheduled for diagnostic EUS were recruited and randomized to receive EA or sham-electroacupuncture (SA). The primary outcome was the dosage of propofol used. Other outcome measurements included pain scores, anxiety scores, satisfaction scores, patients' willingness to repeat the procedure, total procedure time, and adverse events. Results: A total of 128 patients were recruited to the study. The patients who received EA had significantly fewer requirements for patient-controlled sedation and analgesia (PCA). The median (interquartile range) number of demands for PCA (2 [1-5] vs 16.5 [8.5-33.8]; P < .001), the number of successful demands (2 [1-4] vs 9 [5.3-13]; P < .001), and the total dose of propofol (0.15 [0.08-0.34] vs 0.77 [0.38-1.09]; P < .001) and alfentanil (0.38 [0.20-0.86] vs 1.92 [0.94-2.72]; P < .001) were all significantly less. Patients who received EA also had significantly lower procedural pain scores and anxiety scores (P < .001), and higher satisfaction scores (P < .001), and they were more willing to repeat the procedure (P < .001). Being in the SA group and the procedure time were significant predictors of increased PCA demands (P < .001 and P = .009, respectively). Conclusions: In conclusion, the use of EA reduced sedative and analgesia demands, improved patient experience, and was associated with a low risk of adverse events during diagnostic EUS.
C1 [Teoh, Anthony Yuen Bun; Chong, Charing Ching Ning; Leung, Wing Wa; Ng, Enders Kwok Wai; Lai, Paul Bo San; Lau, James Yun Wong] Chinese Univ Hong Kong, Dept Surg, Shatin, Hong Kong, Peoples R China.
   [Chan, Simon Kin Cheong; Lau, James Yun Wong] Chinese Univ Hong Kong, Dept Anaesthesia & Intens Care, Shatin, Hong Kong, Peoples R China.
   [Tse, Yee Kit; Ng, Enders Kwok Wai; Lai, Paul Bo San; Wu, Justin Che Yuen] Chinese Univ Hong Kong, Inst Digest Dis, Shatin, Hong Kong, Peoples R China.
   [Wu, Justin Che Yuen] Chinese Univ Hong Kong, Inst Integrat Med, Prince Wales Hosp, Shatin, Hong Kong, Peoples R China.
C3 Chinese University of Hong Kong; Chinese University of Hong Kong; Chinese University of Hong Kong; Prince of Wales Hospital Hong Kong; Chinese University of Hong Kong
RP Teoh, AYB (corresponding author), Chinese Univ Hong Kong, Prince Wales Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China.
EM anthonyteoh@surgery.cuhk.edu.hk
FU Health and Medical Research Fund, Hong Kong
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NR 25
TC 13
Z9 15
U1 1
U2 18
PU MOSBY-ELSEVIER
PI NEW YORK
PA 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0016-5107
EI 1097-6779
J9 GASTROINTEST ENDOSC
JI Gastrointest. Endosc.
PD FEB 15
PY 2018
VL 87
IS 2
BP 476
EP 485
DI 10.1016/j.gie.2017.07.029
PG 10
WC Gastroenterology & Hepatology
SC Gastroenterology & Hepatology
GA FV2LO
UT WOS:000424398500022
PM 28750840
DA 2026-01-16
ER

PT J
AU de Barros, JC
   Valentim, LG
   Dias, RC
   Pereira, AHT
   Di Santis, GW
   Arias, MVB
AF de Barros, Juliana Campos
   Valentim, Larissa Garbelini
   Dias, Raira Costa
   Tanaka Pereira, Alfredo Hajime
   Di Santis, Giovana Wingeter
   Bahr Arias, Monica Vicky
TI Surgical Excision of an Osteochondroma in a Nerve Root of the Cauda Equina of a Dog
SO ACTA SCIENTIAE VETERINARIAE
LA Portuguese
DT Article
DE diseases; nervous system; neoplasms; spinal nerve roots
ID imaging diagnosis; extradural chondroma; cervical-spine
AB Background: Spinal neoplasms are classified into extradural, in tradural/extramedullary or in tramedullary. Intradural/extramedullary tumors include meningiomas and nerve sheath tumors, which arise from meninges or peripheral nerves around the spinal cord. Clinical signs are related to dysfunction of the involved nerve and include pain, nerve root signature and atrophy. Osteochondromas are benign tumors located within the bone, on its surface or in extra-osseous regions, when they are classified as soft tissue osteochondoma. The aim of this study is to describe a case of an osteochondroma in a nervous root of the cauda equina in a dog, whose surgical resection allowed the resolution of the clinical signs. Case: A 12-year-old, male, Labrador Retriever dog, was presented with a 40-day history of progressive, painful, pelvic limb paresis, with no improvement when treated with analgesics and acupuncture. Neurological abnormalities included paraparesis, sometimes worse in the left pelvic limb, that was carried flexed at the level of the stifle, hindlimb atrophy, decreased interdigital reflexes and pain in the lumbar spinal region, mainly over L6 vertebra. Results of blood count and serum biochemical analysis were unremarkable. Computed tomography (CT) of the lumbosacral area was performed and the evaluation of images in transverse and reconstructed dorsal and sagittal planes allowed the visualization of a hyperattenuating and calcified round structure with 8 mm x 6 mm, in the left side of vertebral canal, at the level of caudal epiphysis of L6. Lumbosacral (L7-S1) CT abnormalities, as subchondral sclerosis, mild disc margin bulging, spondylosis deformans and foraminal proliferation were also observed but were considered clinically insignificant. Then, a dorsal 1.6 laminectomy was performed and after opening of the vertebral canal it was observed the presence of an ovoid mass, in the left side of the medullary cone, measuring approximately 0.9 cm in length, originating from a sacral nerve root. This structure was excised and submitted to histopathological evaluation. The dog improved after surgery without any complications, and neurological functions were gradually recovered. The histopathology of the mass was confirmed as an osteochondroma. Discussion: The history and neurologic examination findings as well the improvement after surgery were compatible with the lesion visualized by TC in L6, rather than the degenerative changes in L7-S1. Regarding the position of the mass, the main differential would be nerve sheath tumor, one of the most common types of primary neoplasia of the peripheral nervous system, however in a CT study in dogs with brachial plexus and nerve roots neoplasms, calcification of the tumor was not observed. Most of benign cartilaginous tumors of soft tissue are chondromas/osteochondromas, and this lesion should not be confused with multiple osteochondroma or multiple cartilaginous exostoses, which have been reported as multifocal, proliferative lesions involving the surface of ribs, vertebrae and pelvis of young dogs. If this lesion is unique, it is called osteochondroma. There are two reports of chondromas into the first lumbar vertebrae of dogs, with adherence to the floor of the vertebral canal and one report of an osteochondroma originated from the left pedicle of T11 in a cat. Radiculopathy and myelopathy caused by osteochondromas inside the spine are rare in humans and description of this tumor arising from nerve roots were not found in the veterinary literature. Probably the origin of the mass was metaplasia of the meninges surrounding the nervous root. In conclusion, neurological examination, CT and surgical exploration allowed the diagnosis and removal of a soft tissue osteochondroma, a rare benign tumor, with good patient recovery.
C1 [de Barros, Juliana Campos; Valentim, Larissa Garbelini; Dias, Raira Costa; Tanaka Pereira, Alfredo Hajime] MV Autonomo, Londrina, Parana, Brazil.
   [Di Santis, Giovana Wingeter] Univ Estadual Londrina UEL, Dept Med Vet Prevent, Londrina, Parana, Brazil.
   [Bahr Arias, Monica Vicky] Univ Estadual Londrina UEL, Dept Clin Vet, Londrina, Parana, Brazil.
C3 Universidade Estadual de Londrina; Universidade Estadual de Londrina
RP Arias, MVB (corresponding author), Univ Estadual Londrina UEL, Rodovia Celso Garcia Cid,Km 380 Caixa Postal 1001, BR-86051970 Londrina, Parana, Brazil.
EM vicky@uel.br
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NR 22
TC 0
Z9 0
U1 0
U2 7
PU UNIV FED RIO GRANDE DO SUL
PI PORTO ALEGRE RS
PA FAC VET, CAIXA POSTAL 15017, PORTO ALEGRE RS, 91501-570, BRAZIL
SN 1678-0345
EI 1679-9216
J9 ACTA SCI VET
JI Acta Sci. Vet.
PD JUN 15
PY 2018
VL 46
IS 
BP 
EP 
DI 
PG 6
WC Veterinary Sciences
SC Veterinary Sciences
GA VJ5IA
UT WOS:000606326600076
DA 2026-01-16
ER

PT J
AU Huang, W
   Yu, TY
   Long, WF
   Xiao, JB
AF Huang, Wei
   Yu, Ting-Yu
   Long, Wen-Fei
   Xiao, Jian-Bin
TI [Application of Transcutaneous Electrical Acupoint Stimulation Combined with
SO Zhen ci yan jiu = Acupuncture research
LA chi
DT Journal Article
DE Clinical trial; Enhanced recovery after surgery; Laparoscopic colorectal cancer resection; Transcutaneous electrical acupoint stimulation; Transversus abdominis plane block
AB OBJECTIVE: To explore the effect of transcutaneous electrical acupoint  stimulation (TEAS) combined with transversus abdominis plane (TAP) block in the  enhanced recovery after surgery (ERAS) in patients undergoing laparoscopic  colorectal cancer resection (LCCR). METHODS: A total of 101 patients undergoing  LCCR were randomly divided into three groups: control (n＝34), TAP (n＝35) and  TEAS＋TAP (n＝32). Conventional perioperative anesthesia management of the 3 groups  was performed according to the ERAS guidelines. All the patients experienced  patient controlled epidural analgesia (PCEA), and those of the TAP and TEAS＋TAP  groups received TAP block by injection of 0.3% Roperca hydrochloride (15 mL) into  the space between the internal oblique and the transverse abdominis after  induction of anesthesia. For patients of the TEAS＋TAP group, TEAS (2 Hz/10 Hz, an  endurable stimulation strength) was applied to bilateral Zusanli (ST 36) from 30  min before anesthesia to the end of the surgery. The blood glucose value and  dosage of Remifentanil used were recorded. The pain severity was assessed at 4,  12, 24 and 48 h after surgery by using visual analogue scale (VAS). Moreover,  postoperative anal exhaust time, postoperative oral feeding time, postoperative  first ambulation time and postoperative hospital stay length were recorded.  RESULTS: The total dosages of Remifentanil used during surgery, and the blood  glucose levels were significantly lower in the TAP and TEAS＋TAP groups than in  the control group (P<0.05), but had no significant differences between the TAP  and TEAS＋TAP groups (P>0.05). The VAS scores of the TAP and TEAS＋TAP groups were  considerably lower than those of the control group at 4, 12, 24 and 48 h after  surgery (P<0.05, except 48 h of TAP group). Of the 34, 35 and 32 cases in the  control, TAP and TEAS＋TAP groups, 5(14.7%), 3(8.6%) and 1(3.1%) on the 1(st) day  post-surgery, and 2(5.9%), 0(0) and 0(0) on the 2(nd) day after surgery  experienced nausea and vomiting. The postoperative anal exhaust time and  postoperative oral feeding time were significantly earlier in both TAP and  TEAS＋TAP groups than in the control group (P<0.05), and the exhaust time of the  TEAS＋TAP group was even earlier than that of the TAP group (P<0.05). No  significant differences were found among the 3 groups in the postoperative  ambulation time and postoperative hospitalization time (P>0.05). CONCLUSION: TEAS  combined with TAP block analgesia is superior to simple TAP block analgesia in  relieving postoperative pain, shortening the recovery time of gastrointestinal  function and promoting postoperative rehabilitation in patients undergoing LCCR.
C1 The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China.
   The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China.
   The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China.
   The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China.
NR 0
TC 0
SN 
EI 1000-060
J9 Zhen Ci Yan Jiu
PD OCT 27
PY 2018
VL 43
IS 10
BP 611
EP 5
DI 10.13702/j.1000-0607.180005
PG -606
WC Abdominal Muscles; Acupuncture Points; Analgesics, Opioid; Colorectal Neoplasms; therapy; Humans; Laparoscopy; Nerve Block; Pain Measurement; Pain, Postoperative
UT PubMed:30365254
PM 30365254
DA 2018-10-27
ER

PT J
AU Dusek, JA
   Griffin, KH
   Finch, MD
   Rivard, RL
   Watson, D
AF Dusek, Jeffery A.
   Griffin, Kristen H.
   Finch, Michael D.
   Rivard, Rachael L.
   Watson, David
TI Cost Savings from Reducing Pain Through the Delivery of Integrative Medicine Program to Hospitalized Patients
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Article
DE integrative medicine; outcomes research; pain; electronic health record; costs and cost analysis; inpatients; hospitalization
ID acute postoperative pain; randomized controlled-trials; alternative medicine; massage therapy; back-pain; complementary; acupuncture; metaanalysis; economics; oncology
AB Objectives: An important task facing hospitals is improving pain management without raising costs. Integrative medicine (IM), a promising nonpharmacologic pain management strategy, is yet to be examined for its cost implications in an inpatient setting. This institution has had an inpatient IM department for over a decade. The purpose was to examine the relationship between changes in patients' pain, as a result of receiving IM therapy, and total cost of care during an inpatient hospital admission. Design: In this retrospective analysis, data from an EPIC-based electronic health record (EHR) patient demographics, length of stay (LOS), and All Patient Refined Diagnosis Related Groups (APR-DRG) severity of illness measures were utilized. IM practitioners collected and entered patient-reported pain scores into the EHR. The authors regressed the demographic, change in pain, LOS, and APR-DRG variables with changes in pain on total cost for the hospital admission. To estimate cost savings to the hospital, they computed the average reduction in cost associated with reduction in pain by multiplying the coefficient for change in pain by average total cost. Setting/Location: A large, tertiary care hospital in Minneapolis, MN. Subjects: Adult inpatient admissions, 2730, during the study period where patients received IM for pain and met eligibility criteria. Intervention: IM services provided to inpatients. Outcome measures: Change in pain on an 11-point numeric rating scale before and after initial IM sessions; total costs for hospital admissions. Results: Both LOS and age were found to increase cost, as did being white, male, married, and having APR-DRG severity coded as extreme. For patients receiving IM therapies, pain was reduced by an average of 2.05 points and this pain reduction was associated with a cost savings of $898 per hospital admission. Conclusions: For patients receiving IM therapies, pain was significantly reduced and costs were lowered by about 4%.
C1 [Dusek, Jeffery A.; Griffin, Kristen H.; Rivard, Rachael L.] Allina Hlth, Penny George Inst Hlth & Healing, Integrat Hlth Res Ctr, Minneapolis, MN USA.
   [Finch, Michael D.; Watson, David] Childrens Minnesota, Childrens Minnesota Res Inst, Minneapolis, MN USA.
   [Finch, Michael D.; Watson, David] Kripalu Ctr Yoga & Hlth, 57 Interlaken Rd, Stockbridge, MA 01262 USA.
C3 Allina Health System; Children's Hospitals & Clinics of Minnesota
RP Dusek, JA (corresponding author), Kripalu Ctr Yoga & Hlth, 57 Interlaken Rd, Stockbridge, MA 01262 USA.
EM jeffd@kripalu.org
FU National Center for Complementary and Integrative Health (NCCIH) of the National Institutes of Health [AT006518]
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NR 54
TC 49
Z9 62
U1 0
U2 10
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD JUN 15
PY 2018
VL 24
IS 6
BP 557
EP 563
DI 10.1089/acm.2017.0203
EA FEB 2018
PG 7
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA HK9XQ
UT WOS:000426036900001
PM 29474095
DA 2026-01-16
ER

PT J
AU Lam, WL
   Yeung, WF
   Wong, MK
   Cheung, CW
   Chan, KKL
   Ngan, HYS
   Wong, CKH
   Chen, HY
   Lao, LX
AF Lam, Wing Lok
   Yeung, Wing Fai
   Wong, Mei Kuen
   Cheung, Chi Wai
   Chan, Karen Kar Loen
   Ngan, Hextan Yuen Sheung
   Wong, Carlos King Ho
   Chen, Hai Yong
   Lao, Lixing
TI Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial
SO TRIALS
LA English
DT Article
DE RCT; Health economic analysis; Placebo; Analgesia; Morphine consumption; AUC; Acupuncture; Operation
ID oral-surgery; rating-scale; metaanalysis; recovery
AB Background: Postoperative pain is a major complaint following abdominal surgery for gynecological diseases. Effective postoperative pain control after abdominal surgery is particularly important for patient recovery, mobility, and satisfaction. Acupuncture has been commonly used for pain management. However, its efficacy in postoperative pain control is inconclusive and health economic evaluation is limited. Methods: A randomized, sham-controlled, patient-and-assessor-blind trial is designed to evaluate the efficacy and safety of acupuncture in managing postoperative pain following abdominal surgery of gynecological diseases. Patients who are eligible for laparotomy with a midline incision for gynecological neoplasia, including ovarian mass, uterine mass, and cervical lesions, will be recruited. Seventy-two participants will be randomly allocated to an acupuncture or non-invasive sham control in a 1:1 ratio. Treatment will be done within 2 h before operation, upon arrival to the ward and once daily for 5 days. The Pain Numerical Rating Scale (NRS) on the first 5 days during hospitalization will be the primary outcome and will be analyzed using the area-under-the-curve (AUC) method. The secondary outcome measures include frequency of rescue analgesic use during hospital stay, cumulative morphine consumption; quality of recovery as measured by time to recovery variables and the Quality of Recovery-9 (QoR-9); quality of life as measured by the Short Form-6 dimension (SF-6D) and EuroQol-5 Dimension-5 Level (EQ-5D-5 L). The incremental cost-effectiveness ratio of acupuncture vs sham acupuncture will be calculated. Discussion: This study protocol provides an example of integrative medicine practice in a hospital setting for the management of postoperative pain using acupuncture treatment. The acupuncture treatment protocol, if proven to be effective, can be implemented in routine settings to play a role in postoperative pain management for patients who have undergone abdominal surgery for gynecological diseases.
C1 [Lam, Wing Lok; Wong, Mei Kuen; Chen, Hai Yong; Lao, Lixing] Univ Hong Kong, Sch Chinese Med, 10 Sassoon Rd, Pokfulam, Hong Kong, Peoples R China.
   [Yeung, Wing Fai] Hong Kong Polytech Univ, Sch Nursing, Kowloon, Hong Kong, Peoples R China.
   [Cheung, Chi Wai] Univ Hong Kong, Dept Anesthesiol, Queen Mary Hosp, 4-F K Block,102 Pokfulam Rd, Pokfulam, Hong Kong, Peoples R China.
   [Chan, Karen Kar Loen; Ngan, Hextan Yuen Sheung] Univ Hong Kong, Dept Obstet & Gynecol, Queen Mary Hosp, 6-F Professorial Block,102 Pokfulam Rd, Pokfulam, Hong Kong, Peoples R China.
   [Wong, Carlos King Ho] Univ Hong Kong, Dept Family Med & Primary Care, Ap Lei Chau Clin, 3-F,161 Main St, Pokfulam, Hong Kong, Peoples R China.
C3 University of Hong Kong; Hong Kong Polytechnic University; University of Hong Kong; University of Hong Kong; University of Hong Kong
RP Lao, LX (corresponding author), Univ Hong Kong, Sch Chinese Med, 10 Sassoon Rd, Pokfulam, Hong Kong, Peoples R China.
EM lxlao1@hku.hk
FU Health and Medical Research Fund (HMRF), Hong Kong [13142951]
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NR 46
TC 7
Z9 8
U1 1
U2 6
PU BMC
PI LONDON
PA CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
SN 1745-6215
EI 
J9 TRIALS
JI Trials
PD JAN 4
PY 2018
VL 19
IS 
BP 
EP 
DI 10.1186/s13063-017-2359-8
PG 13
WC Medicine, Research & Experimental
SC Research & Experimental Medicine
GA FS2KK
UT WOS:000419607200007
PM 29301556
DA 2026-01-16
ER

PT J
AU Xu, L
   Wan, Y
   Huang, J
   Xu, F
AF Xu, Lili
   Wan, Yongxian
   Huang, Juan
   Xu, Fangyuan
TI Clinical analysis of electroacupuncture and multiple acupoint stimulation in
SO Journal of cancer research and therapeutics
LA English
DT Journal Article
DE Cancerous pain; electroacupuncture; hepatocellular carcinoma; multiple acupoint stimulation; pain relief
AB OBJECTIVE: The objective of this study is to investigate the clinical efficacy  and safety of electroacupuncture and multiple acupoint stimulation in relieving  cancer pain in patients with advanced hepatocellular carcinoma. METHODS:  Sixty-five cases of advanced hepatocellular carcinoma with cancer pain were  selected in our hospital and were divided into electroacupuncture multiple  acupoint stimulation group (electroacupuncture group) (n = 32) and fentanyl  transdermal patch analgesia group (control group) (n = 33) according to analgesic  methods and intentions. In the electroacupuncture group, electric acupuncture  treatment was administered at different acupoints, including Baihui, Quchi,  Neiguan, Xuehai, Zusanli, and Sanyinjiao acupoint, once a day for 7 days. In the  control group, a fentanyl transdermal patch was placed on the upper left arm  every 3 days and replaced with a continuous external paste once for 7 days. Pain  scores in the two groups before and during the treatment were evaluated with a  visual analog scale (VAS), and adverse reactions during the treatment were  recorded. RESULTS: The VAS pain score of the electroacupuncture group was  significantly decreased on day 3 (P < 0.05), but the pain scores were not  significantly different (P > 0.05) between the two groups 4 days after treatment.  For treatment-related side effects, there were 3 cases of subcutaneous hemorrhage  in the electroacupuncture group; 1 case of skin rashes and 3 cases of nausea and  vomiting in the control group. The incidences of adverse reactions in the two  groups were 9.4% and 12.1%, respectively, without significant difference (P >  0.05). CONCLUSION: Cancer pain in patients with advanced hepatocellular carcinoma  can be alleviated with electroacupuncture and multiple acupoint stimulation, but  the onset pain relief was slow. To improve the analgesic effects of this  technique, the combination of various analgesic methods should be necessary in  early stage of the treatment.
C1 Department of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, PR China.
   Department of Bone and Joint Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, PR China.
   Department of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, PR China.
   Department of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, PR China.
NR 0
TC 0
SN 1998-413
EI 
J9 J Cancer Res Ther
PD MAR 9
PY 2018
VL 14
IS 1
BP 99
EP 102
DI 10.4103/jcrt.JCRT_736_17
PG 3
WC Acupuncture Points; Aged; Cancer Pain; diagnosis; Carcinoma, Hepatocellular; complications; Electroacupuncture; adverse effects; Female; Humans; Liver Neoplasms; complications; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pain Management; Pain Measurement; Treatment Outcome
UT PubMed:29516968
PM 29516968
DA 2018-03-09
ER

PT J
AU Hughes, J
   Cummings, M
   Filshie, J
   Kassab, S
   Leng, G
   Mackereth, P
   MacPherson, H
   de Valois, B
   Fisher, P
AF Hughes, John
   Cummings, Mike
   Filshie, Jacqueline
   Kassab, Sosie
   Leng, Graham
   Mackereth, Peter
   MacPherson, Hugh
   de Valois, Beverley
   Fisher, Peter
TI Ensuring model validity in a feasibility study of acupuncture to improve quality of life in cancer patients undergoing radiotherapy treatment
SO EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
LA English
DT Article
DE Acupuncture; Model validity; Cancer; Randomised controlled trial; Radiotherapy
AB Introduction: A feasibility study of acupuncture for quality of life in cancer patients is planned. The pragmatic randomised controlled trial will aim to assess the feasibility of training radiographers to administer acupuncture to their patients undergoing radiotherapy intended to cure their cancer. The preliminary phase covered in this paper aimed to develop the trial acupuncture intervention and ensure its model validity. Methods: A mixed methods approach will be adopted. Systematic review conducted examining the treatments administered in papers reporting acupuncture treatment for cancer patients. Subsequently, one-day workshop held with an acupuncture expert panel. Informed by the systematic review and their clinical expertise the expert panel devised and agreed the trial acupuncture intervention. Results: The acupuncture expert panel came to a consensus on the trial acupuncture intervention. Trial radiographers will treat patients for 30 min, with needles inserted for approximately 20 min of this time. The trial will employ a standard treatment protocol for constitutional symptoms (fatigue, hot flushes, mood problems, anxiety, depression, and sleep problems) consisting of non traditional ASAD (anxiety, sickness and dyspnoea) acupoints, LI4, LR3, SP6 and ST36. Additional acupoints can be utilised for nausea/vomiting and pain. Guidelines on safe practice were also agreed. Conclusions: Few clinical trials of acupuncture, and complementary medicine interventions generally, document details of the process by which they ensured the model validity of their trial intervention. It is recommended that researchers in acupuncture, and other forms of complementary medicine, adopt appropriate methodological approaches to ensure model validity.
C1 [Hughes, John; Cummings, Mike; Kassab, Sosie; Fisher, Peter] UCLH NHS Trust, Royal London Hosp Integrated Med, Great Ormond St, London WC1N 3HR, England.
   [Filshie, Jacqueline] Royal Marsden NHS Fdn Trust, Fulham Rd, London SW3 6JJ, England.
   [Leng, Graham] Hosp Good Shepherd, Gordon Lane, Chester CH2 4DG, Cheshire, England.
   [Mackereth, Peter] Christie Hosp NHS Trust, Wilmslow Rd, Manchester M20 4BX, Lancs, England.
   [MacPherson, Hugh] Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England.
   [de Valois, Beverley] Mt Vernon Canc Ctr, Lynda Jackson Macmillan Ctr, Northwood HA6 2RN, Middx, England.
C3 University College London Hospitals NHS Foundation Trust; Royal London Hospital For Integrated Medicine; University of London; University College London; Great Ormond Street Hospital for Children NHS Foundation Trust; Royal Marsden NHS Foundation Trust; Christie NHS Foundation Trust; Christie Hospital; University of York - UK; Mount Vernon Cancer Centre
RP Hughes, J (corresponding author), Royal London Hosp Integrated Med, 60 Great Ormond St, London WC1N 3HR, England.
EM John.Hughes8@nhs.net
FU UCLH
CR Boon H, 2007, EVID-BASED COMPL ALT, V4, P279, DOI 10.1093/ecam/nel079
   Bornhoft Gudrun, 2006, BMC MED RES METHODOL, V6, P56
   Filshie J, 2001, ACUPUNCT MED, V19, P117
   Filshie Jacqueline, 2006, ACUPUNCT MED, V24, P172
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NR 9
TC 3
Z9 3
U1 0
U2 8
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 1876-3820
EI 1876-3839
J9 EUR J INTEGR MED
JI Eur. J. Integr. Med.
PD AUG 15
PY 2018
VL 21
IS 
BP 50
EP 52
DI 10.1016/j.eujim.2018.06.010
PG 3
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GS5UR
UT WOS:000443737400009
DA 2026-01-16
ER

PT J
AU Li, ZG
   Li, Y
   Li, XK
   Zhang, LD
   Zhao, NQ
   Du, HB
   Zhou, B
   Ye, YA
AF Li, Zhiguo
   Li, Ying
   Li, Xiaoke
   Zhang, Ludan
   Zhao, Nanqi
   Du, Hongbo
   Zhou, Bo
   Ye, Yong'an
TI Statins on hepatocellular carcinoma risk in hepatitis B or C patients protocol for a systematic review and meta-analysis
SO MEDICINE
LA English
DT Review
DE hepatitis; hepatocellular carcinoma; statins; systematic review
ID low-back-pain; lumbar disc herniation; intervertebral disc; clinical importance; functional status; acupotomy; outcm; acupuncture; medicine; safety
AB Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Chronic hepatitis B (HBV) and C virus (HCV) infection causes liver cancer. This protocol is to provide the methods used to assess the relationship between statins and HCC risk in hepatitis B or C patients. Methods: We will search comprehensively the PubMed (medline), Embase, Web of Science, Cochrane Library, and China National Knowledge Infrastructure, Wanfang Database from their inception to November 2017. We will include studies that evaluated and clearly defined exposure to statins, reported the HCC incidence in hepatitis B/C patients or HBV/HCV-related cirrhosis patients, provided effective comparison groups, and reported risk estimates, such as hazard ratios, relative risks, or odds ratios with corresponding 95% confidence intervals or sufficient data for their estimation. We will use Stata (version 15.0) to compute the data synthesis carefully when a meta-analysis is allowed. Results: This study will provide a high-quality synthesis of current evidence of statins on HCC risk in hepatitis B or C patients. Conclusion: The conclusion of our systematic review will provide evidence to judge whether statin is an effective intervention for hepatitis B or C patients.
C1 [Li, Zhiguo; Li, Ying; Li, Xiaoke; Zhang, Ludan; Du, Hongbo; Ye, Yong'an] BUCM, Dongzhimen Hosp, Dept Gastroenterol, Beijing 100700, Peoples R China.
   [Li, Zhiguo; Li, Ying; Zhang, Ludan; Zhao, Nanqi; Zhou, Bo] Beijing Univ Chinese Med, Beijing, Peoples R China.
   [Li, Xiaoke; Du, Hongbo; Ye, Yong'an] BUCM, Inst Liver Dis, Beijing, Peoples R China.
   [Zhao, Nanqi] BUCM, Ctr Evidence Based Chinese Med, Beijing, Peoples R China.
C3 Beijing University of Chinese Medicine; Beijing University of Chinese Medicine; Beijing University of Chinese Medicine
RP Ye, YA (corresponding author), BUCM, Dongzhimen Hosp, Dept Gastroenterol, Beijing 100700, Peoples R China.
EM Yeyongan@vip.163.com
FU China National Science and Technology major projects 12th 5-year plan [2012ZX10005004]
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NR 33
TC 7
Z9 7
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD AUG 15
PY 2018
VL 97
IS 34
BP 
EP 
DI 10.1097/MD.0000000000011950
PG 12
WC Medicine, General & Internal
SC General & Internal Medicine
GA GW0XD
UT WOS:000446592300069
PM 30142817
DA 2026-01-16
ER

PT J
AU Choi, HS
   Kang, SY
   Roh, DH
   Choi, SR
   Ryu, Y
   Lee, JH
AF Choi, Hoon-Seong
   Kang, Suk-Yun
   Roh, Dae-Hyun
   Choi, Sheu-Ran
   Ryu, Yeonhee
   Lee, Jang-Hern
TI Bee venom stimulation of a lung meridian acupoint reduces inflammation in carrageenan-induced pleurisy: an alternative therapeutic approach for respiratory inflammation
SO JOURNAL OF VETERINARY SCIENCE
LA English
DT Article
DE acupuncture; anti-inflammation; bee venoms; carrageenan-induced pleurisy
ID induced paw inflammation; water-soluble fraction; antiinflammatory drugs; rheumatoid-arthritis; model; rats; pain; electroacupuncture; acupuncture; activation
AB Respiratory inflammation is a frequent and fatal pathologic state encountered in veterinary medicine. Although diluted bee venom (dBV) has potent anti-inflammatory effects, the clinical use of dBV is limited to several chronic inflammatory diseases. The present study was designed to propose an acupoint dBV treatment as a novel therapeutic strategy for respiratory inflammatory disease. Experimental pleurisy was induced by injection of carrageenan into the left pleural space in mouse. The dBV was injected into a specific lung meridian acupoint (LU-5) or into an arbitrary non-acupoint located near the midline of the back in mouse. The inflammatory responses were evaluated by analyzing inflammatory indicators in pleural exudate. The dBV injection into the LU-5 acupoint significantly suppressed the carrageenan-induced increase of pleural exudate volume, leukocyte accumulation, and myeloperoxidase activity. Moreover, dBV acupoint treatment effectively inhibited the production of interleukin 1 beta, but not tumor necrosis factor alpha in the pleural exudate. On the other hand, dBV treatment at non-acupoint did not inhibit the inflammatory responses in carrageenan-induced pleurisy. The present results demonstrate that dBV stimulation in the LU-5 lung meridian acupoint can produce significant anti-inflammatory effects on carrageenan-induced pleurisy suggesting that dBV acupuncture may be a promising alternative medicine therapy for respiratory inflammatory diseases.
C1 [Choi, Hoon-Seong; Choi, Sheu-Ran; Lee, Jang-Hern] Seoul Natl Univ, Res Inst Vet Sci, PLUS Program Creat Vet Sci Res BK21, Dept Vet Physiol, Seoul 08826, South Korea.
   [Choi, Hoon-Seong; Choi, Sheu-Ran; Lee, Jang-Hern] Seoul Natl Univ, Coll Vet Med, Seoul 08826, South Korea.
   [Kang, Suk-Yun; Ryu, Yeonhee] Korea Inst Oriental Med, KM Fundamental Res Div, Daejeon 34054, South Korea.
   [Roh, Dae-Hyun] Kyung Hee Univ, Sch Dent, Dept Oral Physiol, Seoul 02447, South Korea.
C3 Seoul National University (SNU); Seoul National University (SNU); Korea Institute of Oriental Medicine (KIOM); Kyung Hee University
RP Lee, JH (corresponding author), Seoul Natl Univ, Res Inst Vet Sci, PLUS Program Creat Vet Sci Res BK21, Dept Vet Physiol, Seoul 08826, South Korea.; Lee, JH (corresponding author), Seoul Natl Univ, Coll Vet Med, Seoul 08826, South Korea.; Ryu, Y (corresponding author), Korea Inst Oriental Med, KM Fundamental Res Div, Daejeon 34054, South Korea.
EM yhryu@kiom.re.kr; jhl1101@snu.ac.kr
FU Korea Institute of Oriental Medicine (Daejeon, Republic of Korea) [K18181]
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NR 39
TC 8
Z9 9
U1 1
U2 8
PU KOREAN SOC VETERINARY SCIENCE
PI SEOUL
PA SEOUL NATL UNIV,  COLLEGE VETERINARY MEDICINE,, SEOUL, 151-742, SOUTH KOREA
SN 1229-845X
EI 1976-555X
J9 J VET SCI
JI J. Vet. Sci.
PD SEP 15
PY 2018
VL 19
IS 5
BP 708
EP 715
DI 10.4142/jvs.2018.19.5.708
PG 8
WC Veterinary Sciences
SC Veterinary Sciences
GA GV2TS
UT WOS:000445944700016
PM 29929357
DA 2026-01-16
ER

PT J
AU Xia, BJ
   Xie, YP
   Hu, SF
   Xu, TT
   Tong, PJ
AF Xia, Bingjiang
   Xie, Yiping
   Hu, Songfeng
   Xu, Taotao
   Tong, Peijian
TI Effect of Auricular Point Acupressure on Axial Neck Pain After Anterior Cervical Discectomy and Fusion: A Randomized Controlled Trial
SO PAIN MEDICINE
LA English
DT Article
DE Auricular Point Acupressure; Axial Neck Pain; Anterior Cervical Discectomy and Fusion
ID intervertebral disc; disorders
AB Objectives. To evaluate the effect of auricular point acupressure (APA) on axial neck pain after anterior cervical discectomy and fusion (ACDF) surgery. Design. A prospective randomized controlled trial was performed. Subjects and setting. Twenty-nine participants were randomly divided into two groups, real or sham APA. Participants were enrolled from Shaoxing Hospital of Traditional Chinese Medicine, affiliated with Zhejiang Chinese Medical University. Methods. Eligible participants received a four-week real or sham APA treatment according to their assigned groups. The clinical outcomes were assessed by the criteria of Hosono et al., the Brief Pain Inventory Short Form (BPI), and the 36-item Short Form Health Survey (SF-36). In addition, plasma interleukin (IL)-1 beta, IL-6, and tumor necrosis factor (TNF)-alpha were analyzed. Results. Patients with severe or moderate axial neck pain accounted for 28.6% and 35.7% in the real APA group at the end of treatment and one-month follow-up. BPI scores were decreased in the real APA group at the end of treatment and one-month follow-up. The total mean score of SF-36 was improved in the real APA group and significantly higher than in the sham APA group. Additional, the levels of IL-1 beta, IL-6, and TNF-alpha were decreased in the real APA group. Conclusions. The findings supported the therapeutic effect of APA treatment on axial neck pain after ACDF surgery, and they exert the possible therapeutic effect on downregulating the levels of plasma IL-1 beta, IL-6, and TNF-alpha.
C1 [Xia, Bingjiang; Hu, Songfeng] Zhejiang Chinese Med Univ, Shaoxing Hosp Tradit Chinese Med TCM, Shaoxing, Zhejiang, Peoples R China.
   [Xia, Bingjiang; Xu, Taotao; Tong, Peijian] Zhejiang Chinese Med Univ, Hangzhou 310053, Zhejiang, Peoples R China.
   [Xia, Bingjiang; Hu, Songfeng] Res Dept Spine & Joint Shaoxing, Shaoxing, Zhejiang, Peoples R China.
   [Xie, Yiping] Shangyu Hosp TCM, Shaoxing, Zhejiang, Peoples R China.
C3 Zhejiang Chinese Medical University; Zhejiang Chinese Medical University
RP Tong, PJ (corresponding author), Zhejiang Chinese Med Univ, Hangzhou 310053, Zhejiang, Peoples R China.
EM zhongxiyijieheguke@163.com
FU State Administration of Tradition Chinese Medicine of Zhejiang province [2016ZB132]; Science Technology Bureau of Shaoxing [2015B70060]
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NR 27
TC 18
Z9 20
U1 0
U2 15
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1526-2375
EI 1526-4637
J9 PAIN MED
JI Pain Med.
PD JAN 15
PY 2018
VL 19
IS 1
BP 193
EP 201
DI 10.1093/pm/pnx112
PG 9
WC Anesthesiology; Medicine, General & Internal
SC Anesthesiology; General & Internal Medicine
GA FT0UG
UT WOS:000422842800021
PM 28505292
DA 2026-01-16
ER

PT J
AU Seo, YJ
   Jeong, YS
   Park, HS
   Park, SW
   Choi, JY
   Jung, KJ
   Lim, JY
AF Seo, Young Jae
   Jeong, Yong Sung
   Park, Hyo Sik
   Park, Shin Who
   Choi, Ja Young
   Jung, Kang Jae
   Lim, Jong Youb
TI Late-Onset Post-radiation Lymphedema Provoked by Bee Venom Therapy: A Case
SO Annals of rehabilitation medicine
LA English
DT Journal Article
DE Acupuncture; Bee venoms; Lymphedema
AB Lymphedema is a common complication associated with cancer itself or with cancer  treatment. Lymphedema infrequently occurs after drug therapy. Bee venom is one of  the materials used in acupuncture, and it has been used in the treatment of a  variety of inflammatory diseases including arthritis. We report a 74-year-old  male patient with late-onset post-radiation lymphedema provoked by bee venom  therapy. He was free of lymphedema for 5 years after the complete remission of  prostate cancer which had been treated with transurethral resection and radiation  therapy. The patient developed left leg swelling after undergoing bee venom  therapy for left hip pain. Computed tomography and lymphoscintigraphy showed  lymphedema without tumor recurrence or infection. The lymphatic system was  suspected to be injured by bee venom therapy and lymphedema was provoked. Bee  venom therapy should be used cautiously in patients prone to lymphedema.
C1 Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
   Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
   Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
   Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
   Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
   Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
   Department of Rehabilitation Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
NR 0
TC 0
SN 2234-065
EI 2234-064
J9 Ann Rehabil Med
PD SEP 6
PY 2018
VL 42
IS 4
BP 626
EP 629
DI 10.5535/arm.2018.42.4.626
PG 3
UT PubMed:30180534
PM 30180534
DA 2018-09-06
ER

PT J
AU Lu, WD
   Rosenthal, DS
AF Lu, Weidong
   Rosenthal, David S.
TI Oncology Acupuncture for Chronic Pain in Cancer Survivors: A Reflection on the American Society of Clinical Oncology Chronic Pain Guideline
SO HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
LA English
DT Article
DE Oncology acupuncture; ASCO practice guideline; Chronic pain; Cancer survivors
ID randomized controlled-trial; breast-cancer; integrative oncology; complementary therapy; arthralgia; management; women; electroacupuncture; stimulation; symptoms
AB Chronic pain syndromes associated with cancer treatment are common but difficult to manage. The American Society of Clinical Oncology recently published a practice guideline to address the unmet needs of cancer survivors, Management of Chronic Pain in Survivors of Adult Cancers, which stresses the importance of implementing integrative therapies, including acupuncture. This article focuses on randomized clinical trials of acupuncture for chronic pain in cancer survivors, including its use in chemotherapy-induced peripheral neuropathy, aromatase inhibitor associated arthralgia, and post neck dissection pain, and provides future directions of oncology acupuncture research in cancer survivorship. The features of oncology acupuncture are also discussed.
C1 [Lu, Weidong; Rosenthal, David S.] Harvard Med Sch, Leonard P Zakim Ctr Integrat Therapies & Hlth Liv, Dana Farber Canc Inst, 450 Brookline Ave, Boston, MA 02215 USA.
C3 Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Dana-Farber Cancer Institute
RP Lu, WD (corresponding author), Harvard Med Sch, Leonard P Zakim Ctr Integrat Therapies & Hlth Liv, Dana Farber Canc Inst, 450 Brookline Ave, Boston, MA 02215 USA.
EM weidong_lu@dfci.harvard.edu
FU Asia-Pacific Cancer Research Fund
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NR 43
TC 25
Z9 26
U1 0
U2 36
PU W B SAUNDERS CO-ELSEVIER INC
PI PHILADELPHIA
PA 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA
SN 0889-8588
EI 1558-1977
J9 HEMATOL ONCOL CLIN N
JI Hematol. Oncol. Clin. North Am.
PD JUN 15
PY 2018
VL 32
IS 3
BP 519
EP +
DI 10.1016/j.hoc.2018.01.009
PG 16
WC Oncology; Hematology
SC Oncology; Hematology
GA GI8DW
UT WOS:000434753000015
PM 29729786
DA 2026-01-16
ER

PT J
AU Ruela, LD
   Iunes, DH
   Nogueira, DA
   Stefanello, J
   Gradim, CVC
AF Ruela, Ludmila de Oliveira
   Iunes, Denise Hollanda
   Nogueira, Denismar Alves
   Stefanello, Juliana
   Cortes Gradim, Clicia Valim
TI Effectiveness of auricular acupuncture in the treatment of cancer pain: randomized clinical trial
SO REVISTA DA ESCOLA DE ENFERMAGEM DA USP
LA Portuguese
DT Article
DE Acupuncture; Ear; Complementary Therapies; Pain; Neoplasms; Oncology Nursing
ID management
AB Objective: To evaluate the effectiveness of auricular acupuncture in the pain of cancer patients receiving chemotherapy and to verify if there were alterations in the use of analgesics after the application of this intervention. Method: Randomized controlled trial with cancer patients with complaints of pain greater than or equal to four in the Numerical Pain Scale. Two parallel groups were created, an Experimental group, which received auricular acupuncture at energy balance points and at points indicated for the treatment of pain, and a Placebo group, in which fixed placebo points were used. Both groups received the application of semipermanent needles in eight sessions. Results: 31 cancer patients participated in the study. After the eight auricular acupuncture sessions, there was a significant difference between the groups regarding the reduction of pain intensity (p < 0.001) and of the use of medications (p < 0.05). Conclusion: Auricular acupuncture was effective in reducing the pain of patients receiving chemotherapy.
C1 [Ruela, Ludmila de Oliveira; Cortes Gradim, Clicia Valim] Univ Fed Alfenas, Escola Enfermagem, Alfenas, MG, Brazil.
   [Iunes, Denise Hollanda] Univ Fed Alfenas, Inst Ciencias Motricidade Alfenas, Alfenas, MG, Brazil.
   [Nogueira, Denismar Alves] Univ Fed Alfenas, Inst Ciencias Exatas, Dept Estat, Alfenas, MG, Brazil.
   [Stefanello, Juliana] Univ Sao Paulo, Escola Enfermagem Ribeirao Preto, Dept Maternoinfantil & Saude Publ, Ribeirao Preto, SP, Brazil.
C3 Universidade Federal de Alfenas; Universidade Federal de Alfenas; Universidade Federal de Alfenas; Universidade de Sao Paulo
RP Ruela, LD (corresponding author), Rua Joao Pinheiro 203, BR-37140000 Areado, MG, Brazil.
EM ludmilaoliveira.r@hotmail.com
CR Alimi D, 2003, J CLIN ONCOL, V21, P4120, DOI 10.1200/JCO.2003.09.011
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NR 31
TC 31
Z9 41
U1 1
U2 34
PU UNIV SAO PAOLO
PI CERQUERA CESAR
PA AV  DR ENEAS DE CARVALHO AGUIAR, 419, CERQUERA CESAR, SP 05403-000, BRAZIL
SN 0080-6234
EI 1980-220X
J9 REV ESC ENFERM USP
JI Rev. Esc. Enferm. USP
PD JUN 15
PY 2018
VL 52
IS 
BP 
EP 
DI 10.1590/S1980-220X2017040503402
PG 8
WC Nursing
SC Nursing
GA HF0OT
UT WOS:000453862200002
PM 30570087
DA 2026-01-16
ER

PT J
AU Jung, M
   Rein, N
   Fuchs, B
AF Jung, M.
   Rein, N.
   Fuchs, B.
TI Physical Therapy for Chemotherapy-induced Peripheral Neuropathy in Pediatric Oncology
SO PHYSIKALISCHE MEDIZIN REHABILITATIONSMEDIZIN KURORTMEDIZIN
LA German
DT Article
DE chemotherapy-induced peripheral neuropathy; pediatric oncology; physical therapy; neurologic rehabilitation; systematic review; vinchristin-induced polyneuropathy
ID cancer; children; polyneuropathy; acupuncture; vincristine; performance; management; cipn; life
AB Background Chemotherapy-induced peripheral neuropathy is a frequent side-effect of drugs that are used in the treatment of cancer. People affected can suffer from motor, sensory or autonomy nerve damage. Further medication is used for the treatment of CIPN which can cause further side-effects. Patients should be offered physical therapy treatment to relieve the symptoms. Objective The aim of this article is to give an overview of available literature affecting physical therapy in CIPN in pediatric oncology. Methods To determine relevant literature, a systematic review was conducted in the databases CINAHL, The Cochrane Library, ERIC, MEDPILOT, PEDro, PsycARTICLES, PsycINFO, PubMed and DIMDI. Besides the methodological quality of the identified literature is supposed to be reviewed. Results There is no current literature regarding the subject of this article, so no evaluation of the quality could be carried out. Although several publications concerning adults could be identified and transfer could be established for pediatrics. Conclusion Acupuncture appeared to be effective in the treatment of CIPN in adults. Good results appeared especially regarding pain. Sensorimotor training, balance training, electrotherapy and alternative methods like Reiki and Yoga showed good results for patients symptoms. These treatment methods give a future prospect how CIPN in children can be treated successfully - but further pediatric research is necessary.
C1 [Jung, M.; Fuchs, B.] Hsch Fresenius gGmbH, Sch Therapy & Social Works, Marienburgstr 2, D-65510 Idstein, Germany.
   [Rein, N.] Hsch Fresenius gGmbH, Sch Med, Idstein, Germany.
RP Jung, M (corresponding author), Hsch Fresenius gGmbH, Sch Therapy & Social Works, Marienburgstr 2, D-65510 Idstein, Germany.
EM jung.michael@hs-fresenius.de
CR Cavaletti G, 2002, EUR J CANCER, V38, P1832, DOI 10.1016/S0959-8049(02)00229-0
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NR 30
TC 2
Z9 4
U1 1
U2 18
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0940-6689
EI 1439-085X
J9 PHYS MED REHAB KUROR
JI Physik. Med. Rehabilitationsmed. Kurort.
PD JAN 15
PY 2018
VL 28
IS 1
BP 46
EP 52
DI 10.1055/s-0043-124644
PG 7
WC Rehabilitation; Sport Sciences
SC Rehabilitation; Sport Sciences
GA FW2ZA
UT WOS:000425173100006
DA 2026-01-16
ER

PT J
AU Stomski, NJ
   Petterson, A
   Kristjanson, L
   Lobb, EA
   Phillips, M
   Williamsa, A
   Morrison, P
   Joske, D
AF Stomski, N. J.
   Petterson, A.
   Kristjanson, L.
   Lobb, E. A.
   Phillips, M.
   Williamsa, A.
   Morrison, P.
   Joske, D.
TI The effect of self-selected complementary therapies on cancer patients' quality of life and symptom distress: A prospective cohort study in an integrative oncology setting
SO COMPLEMENTARY THERAPIES IN MEDICINE
LA English
DT Article
DE Cancer; Complementary therapies; Quality of life; Distress; Prospective study
ID alternative medicine; care; pain; communication; acupuncture
AB Objective: To examine the effectiveness of a multifaceted complementary therapies intervention, delivered in a systematic manner within an Australian public hospital setting, on quality of life and symptom distress outcomes for cancer patients. Methods: Adults receiving treatment for any form of cancer were eligible to participate in this study. Self-referred participants were offered a course of six complementary therapy sessions. Measures were administered at baseline, and at the third and sixth visit. The primary outcomes were quality of life and symptom distress. Linear mixed models were used to assess change in the primary outcomes. Results: In total, 1376 cancer patients participated in this study. The linear mixed models demonstrated that there were significant improvements in quality of life and significant reductions in symptom distress over six sessions. Body-based therapies demonstrated significantly superior improvement in quality of life over counselling, but no other differences between therapies were identified. Reduced symptom distress was not significantly associated with any particular type of therapy. Conclusion: A self-selected complementary therapies intervention, provided in an Australian public hospital by accredited therapists, for cancer patients significantly improved quality of life and reduced symptom distress. The effect of this intervention on quality of life has particular salience, since cancer impacts on many areas of people's lives and impairs quality of life.
C1 [Stomski, N. J.; Williamsa, A.; Morrison, P.] Murdoch Univ, Sch Hlth Profess, 90 South St, Murdoch, WA 6150, Australia.
   [Petterson, A.; Joske, D.] Sir Charles Gairdner Hosp, SolarisCare Fdn, Nedlands, WA, Australia.
   [Kristjanson, L.] Swinburne Univ Technol, Chancellery, Hawthorn, Vic, Australia.
   [Lobb, E. A.] Univ Notre Dame Sydney, Sch Med, Darlinghurst, NSW, Australia.
   [Lobb, E. A.] Calvary Hlth Care Sydney, Kogarah, NSW, Australia.
   [Lobb, E. A.] Cunningham Ctr Palliat Care, Darlinghurst, NSW, Australia.
   [Phillips, M.] Harry Perkins Inst Med Res, Nedlands, WA, Australia.
   [Phillips, M.] Univ Western Australia, Ctr Med Res, Crawley, WA, Australia.
   [Phillips, M.] Royal Perth Hosp, Perth, WA, Australia.
   [Williamsa, A.] Sir Charles Gairdner Hosp, Ctr Nursing Res, Nedlands, WA, Australia.
   [Joske, D.] Sir Charles Gairdner Hosp, Dept Haematol, Nedlands, WA, Australia.
   [Joske, D.] Univ Western Australia, Fac Hlth & Med Sci, Crawley, WA, Australia.
C3 Murdoch University; University of Western Australia; Sir Charles Gairdner Hospital; Swinburne University of Technology; The University of Notre Dame Australia; University of Notre Dame Australia - Sydney; University of Notre Dame Australia - Sydney Campus Darlinghurst; Harry Perkins Institute of Medical Research; University of Western Australia; University of Western Australia; East Metropolitan Health Service; Royal Perth Hospital; University of Western Australia; Sir Charles Gairdner Hospital; University of Western Australia; Sir Charles Gairdner Hospital; University of Western Australia
RP Stomski, NJ (corresponding author), Murdoch Univ, Sch Hlth Profess, 90 South St, Murdoch, WA 6150, Australia.
EM N.Stomski@murdoch.edu.au
CR Bardia A, 2006, J CLIN ONCOL, V24, P5457, DOI 10.1200/JCO.2006.08.3725
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NR 23
TC 8
Z9 12
U1 0
U2 13
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0965-2299
EI 1873-6963
J9 COMPLEMENT THER MED
JI Complement. Ther. Med.
PD APR 15
PY 2018
VL 37
IS 
BP 1
EP 5
DI 10.1016/j.ctim.2018.01.006
PG 5
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GD8RT
UT WOS:000430780500001
PM 29609920
DA 2026-01-16
ER

PT J
AU Amraoui, J
   Pouliquen, C
   Fraisse, J
   Dubourdieu, J
   Guzer, SRD
   Leclerc, G
   de Forges, H
   Jarlier, M
   Gutowski, M
   Bleuse, JP
   Janiszewski, C
   Diaz, J
   Cuvillon, P
AF Amraoui, Jibba
   Pouliquen, Camille
   Fraisse, Julien
   Dubourdieu, Jacques
   Guzer, Sophie Rey Dit
   Leclerc, Gilles
   de Forges, Helene
   Jarlier, Marta
   Gutowski, Marian
   Bleuse, Jean-Pierre
   Janiszewski, Chloe
   Diaz, Jesus
   Cuvillon, Philippe
TI Effects of a Hypnosis Session Before General Anesthesia on Postoperative Outcomes in Patients Who Underwent Minor Breast Cancer Surgery The HYPNOSEIN Randomized Clinical Trial
SO JAMA NETWORK OPEN
LA English
DT Article
ID auricular acupuncture; recovery; quality; blocks
AB IMPORTANCE Hypnosis is now widespread in medical practice and is emerging as an alternative technique for pain management and anxiety. However, its effects on postoperative outcomes remain unclear. OBJECTIVE To evaluate the efficacy of a preoperative hypnosis session for reducing postoperative breast pain in patients who underwent minor breast cancer surgery. DESIGN, SETTING, AND PARTICIPANTS The HYPNOSEIN prospective randomized clinical trial was conducted from October 7, 2014, to April 5, 2016. In this multicenter study in France, 150 women scheduled for minor breast cancer surgery were randomized between control and hypnosis arms, and 148 (71 control and 77 hypnosis) were included in the intent-to-treat analysis. INTERVENTION On the day of surgery, eligible patients were randomly assigned (1:1) to the control arm or the hypnosis arm. Patients (but not the care teams) were blinded to the arm to which they were assigned. A 15-minute hypnosis session before general anesthesia in the operating room was performed in the hypnosis arm. MAIN OUTCOMES AND MEASURES The primary end point was breast pain reduction (by 2 on a visual analog scale), assessed immediately before discharge from the postanesthesia care unit (PACU). Secondary end points were nausea/vomiting, fatigue, comfort/well-being, anxiety, and PACU length of stay, assessed at different times until postoperative day 30. RESULTS The median patient age was 57 years (range, 33-79 years) in the control arm and 53 years (range, 20-84 years) in the hypnosis arm. Baseline characteristics were similar in the 2 arms. The median duration of the hypnosis session was 6 minutes (range, 2-15 minutes). The use of intraoperative opioids and hypnotics was lower in the hypnosis arm. The mean (SD) breast pain score (range, 0-10) was 1.75 (1.59) in the control arm vs 2.63 (1.62) in the hypnosis arm (P = .004). At PACU discharge and with longer follow-up, no statistically significant difference in breast pain was reported. Fatigue was significantly lower in the hypnosis arm on the evening of surgery (mean [SD] score, 3.81 [2.15] in the control arm vs 2.99 [2.56] in the hypnosis arm; P = .03). The median PACU length of stay was 60 minutes (range, 20-290 minutes) in the control arm vs 46 minutes (range, 5-100 minutes) in the hypnosis arm (P = .002). Exploratory analyses according to patient perception of whether she received hypnosis showed significantly lower fatigue scores in the perceived hypnosis subgroup on the evening of surgery (mean [SD], 4.13[2.26] for no perceived hypnosis vs 2.97 [2.42] for perceived hypnosis; P = .01). Anxiety was also significantly lower on the evening of surgery in the perceived hypnosis subgroup (mean [SD], 0.75 [1.64] for perceived hypnosis vs 1.67 [2.29] for no perceived hypnosis; P = .03). CONCLUSIONS AND RELEVANCE The results of this study do not support a benefit of hypnosis on postoperative breast pain in women undergoing minor breast cancer surgery. However, other outcomes seem to be improved, which needs to be confirmed by further studies.
C1 [Amraoui, Jibba; Guzer, Sophie Rey Dit; Leclerc, Gilles; Diaz, Jesus; Cuvillon, Philippe] Univ Montpellier, Montpellier Canc Inst ICM, Dept Anesthesia, 208 Ave Apothicaires, F-34298 Montpellier, France.
   [Pouliquen, Camille] Paoli Calmette Inst, Dept Anesthesia, Marseille, France.
   [Fraisse, Julien; Jarlier, Marta] Univ Montpellier, Biometr Unit, Montpellier Canc Inst ICM, Montpellier, France.
   [Dubourdieu, Jacques] Univ Montpellier, CHU Montpellier, Dept Anesthesia, Montpellier, France.
   [de Forges, Helene; Bleuse, Jean-Pierre; Janiszewski, Chloe] Univ Montpellier, Montpellier Canc Inst ICM, Dept Clin Res, Montpellier, France.
   [Gutowski, Marian] Univ Montpellier, Montpellier Canc Inst ICM, Dept Surg Oncol, Montpellier, France.
   [Cuvillon, Philippe] Univ Montpellier, CHU Nimes, Dept Anesthesia, Nimes, France.
C3 Universite de Montpellier; Institut National de la Sante et de la Recherche Medicale (Inserm); Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Montpellier; Universite de Montpellier; CHU de Montpellier; Universite de Montpellier; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Montpellier; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Montpellier; CHU de Nimes
RP Amraoui, J (corresponding author), Univ Montpellier, Montpellier Canc Inst ICM, Dept Anesthesia, 208 Ave Apothicaires, F-34298 Montpellier, France.
EM jibba.amraou@icm.unicancer.fr
FU Montpellier Cancer Institute (ICM)
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NR 23
TC 46
Z9 48
U1 0
U2 12
PU AMER MEDICAL ASSOC
PI CHICAGO
PA 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA
SN 2574-3805
EI 
J9 JAMA NETW OPEN
JI JAMA Netw. Open
PD AUG 15
PY 2018
VL 1
IS 4
BP 
EP 
DI 10.1001/jamanetworkopen.2018.1164
PG 13
WC Medicine, General & Internal
SC General & Internal Medicine
GA HD6JG
UT WOS:000452643200013
PM 30646110
DA 2026-01-16
ER

PT J
AU Hershman, DL
   Unger, JM
   Greenlee, H
   Capodice, JL
   Lew, DL
   Darke, AK
   Kengla, AT
   Melnik, MK
   Jorgensen, CW
   Kreisle, WH
   Minasian, LM
   Fisch, MJ
   Henry, NL
   Crew, KD
AF Hershman, Dawn L
   Unger, Joseph M
   Greenlee, Heather
   Capodice, Jillian L
   Lew, Danika L
   Darke, Amy K
   Kengla, Alice T
   Melnik, Marianne K
   Jorgensen, Carla W
   Kreisle, William H
   Minasian, Lori M
   Fisch, Michael J
   Henry, N Lynn
   Crew, Katherine D
TI Effect of Acupuncture vs Sham Acupuncture or Waitlist Control on Joint Pain
SO JAMA
LA English
DT Journal Article
AB IMPORTANCE: Musculoskeletal symptoms are the most common adverse effects of  aromatase inhibitors and often result in therapy discontinuation. Small studies  suggest that acupuncture may decrease aromatase inhibitor-related joint symptoms.  OBJECTIVE: To determine the effect of acupuncture in reducing aromatase  inhibitor-related joint pain. DESIGN, SETTING, AND PATIENTS: Randomized clinical  trial conducted at 11 academic centers and clinical sites in the United States  from March 2012 to February 2017 (final date of follow-up, September 5, 2017).  Eligible patients were postmenopausal women with early-stage breast cancer who  were taking an aromatase inhibitor and scored at least 3 on the Brief Pain  Inventory Worst Pain (BPI-WP) item (score range, 0-10; higher scores indicate  greater pain). INTERVENTIONS: Patients were randomized 2:1:1 to the true  acupuncture (n = 110), sham acupuncture (n = 59), or waitlist control (n = 57)  group. True acupuncture and sham acupuncture protocols consisted of 12  acupuncture sessions over 6 weeks (2 sessions per week), followed by 1 session  per week for 6 weeks. The waitlist control group did not receive any  intervention. All participants were offered 10 acupuncture sessions to be used  between weeks 24 and 52. MAIN OUTCOMES AND MEASURES: The primary end point was  the 6-week BPI-WP score. Mean 6-week BPI-WP scores were compared by study group  using linear regression, adjusted for baseline pain and stratification factors  (clinically meaningful difference specified as 2 points). RESULTS: Among 226  randomized patients (mean [SD] age, 60.7 [8.6] years; 88% white; mean [SD]  baseline BPI-WP score, 6.6 [1.5]), 206 (91.1%) completed the trial. From baseline  to 6 weeks, the mean observed BPI-WP score decreased by 2.05 points (reduced  pain) in the true acupuncture group, by 1.07 points in the sham acupuncture  group, and by 0.99 points in the waitlist control group. The adjusted difference  for true acupuncture vs sham acupuncture was 0.92 points (95% CI, 0.20-1.65;  P = .01) and for true acupuncture vs waitlist control was 0.96 points (95% CI,  0.24-1.67; P = .01). Patients in the true acupuncture group experienced more  grade 1 bruising compared with patients in the sham acupuncture group (47% vs  25%; P = .01). CONCLUSIONS AND RELEVANCE: Among postmenopausal women with  early-stage breast cancer and aromatase inhibitor-related arthralgias, true  acupuncture compared with sham acupuncture or with waitlist control resulted in a  statistically significant reduction in joint pain at 6 weeks, although the  observed improvement was of uncertain clinical importance. TRIAL REGISTRATION:  ClinicalTrials.gov Identifier: NCT01535066.
C1 Columbia University Medical Center, New York, New York.
   Fred Hutchinson Cancer Research Center, Seattle, Washington.
   SWOG Statistics and Data Management Center, Seattle, Washington.
   Fred Hutchinson Cancer Research Center, Seattle, Washington.
   Mount Sinai Hospital, New York, New York.
   Fred Hutchinson Cancer Research Center, Seattle, Washington.
   SWOG Statistics and Data Management Center, Seattle, Washington.
   Fred Hutchinson Cancer Research Center, Seattle, Washington.
   SWOG Statistics and Data Management Center, Seattle, Washington.
   Kaiser Permanente Medical Center, Walnut Creek, California.
   Spectrum Health Medical Group, Grand Rapids, Michigan.
   NCORP of the Carolinas (Greenville Health System), Greenville, South Carolina.
   St Luke's Mountain States Tumor Institute (PCRC NCORP), Boise, Idaho.
   Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland.
   AIM Specialty Health, Chicago, Illinois.
   University of Utah Huntsman Cancer Institute, Salt Lake City.
NR 0
TC 0
SN 1538-359
EI 0098-748
J9 JAMA
PD JUL 13
PY 2018
VL 320
IS 2
BP 167
EP 176
DI 10.1001/jama.2018.8907
PG 9
WC Acupuncture Therapy; adverse effects; Adult; Aged; Aged, 80 and over; Aromatase Inhibitors; adverse effects; Arthralgia; chemically induced; Breast Neoplasms; drug therapy; Female; Humans; Middle Aged; Neoplasm Staging; Postmenopause; Single-Blind Method; Waiting Lists
UT PubMed:29998338
PM 29998338
DA 2018-07-13
ER

PT J
AU Kim, HW
   Yoo, JE
AF Kim, Hae-Won
   Yoo, Jeong-Eun
TI Inhibitory effect of traditional Korean medicine on the recurrent endometriosis
SO Integrative medicine research
LA English
DT Journal Article
DE Boheotang; Dienogest; Endometriosis; Laparoscopic surgery; traditional Korean medicine
AB Endometriosis is a common benign gynecologic tumor, and it can destroy a  patient's life. Surgery and hormone therapy are established therapies for  endometriosis. However, there are many cases of recurrent endometriosis after  conventional therapies. This report presents a case of a patient who has  repetitive recurrence of endometriosis after laparoscopic excision and hormone  therapy. A 32-years-old female patient first had laparoscopic surgery to remove  endometriosis in 2011. The disease recurred two more times after the first  excision. Hormone therapy by dienogest and two more laparoscopic surgeries were  done in 2012 and 2014. With acupuncture, moxibustion, fumigation therapy, and  herbal medicine therapy, endometriosis didn't recur during treatment and  observation period of 34 months. Menstrual pain numeric rating scales (NRS)  decreased from 2 to none. Shortened menstrual cycle (24 days) after second  surgery became longer (26.63 ± 2.28 days) after traditional Korean medicine  therapy. This case presents the therapeutic potential of TKM for inhibitory  effect on the recurrent endometriosis after laparoscopic excision and hormone  therapy.
C1 Dept. of Korean Medicine Obstetrics & Gynecology, College of Korean Medicine, Dae-jeon University, Korea.
   Dept. of Korean Medicine Obstetrics & Gynecology, College of Korean Medicine, Dae-jeon University, Korea.
NR 0
TC 0
SN 2213-423
EI 2213-422
J9 Integr Med Res
PD OCT 3
PY 2018
VL 7
IS 3
BP 296
EP 301
DI 10.1016/j.imr.2018.07.003
PG 5
UT PubMed:30271719
PM 30271719
DA 2018-10-03
ER

PT J
AU Meng, FF
   Feng, YH
AF Meng, Fan-feng
   Feng, Yan-hong
TI A pilot study of acupuncture at pain acupoints for cervical cancer pain
SO MEDICINE
LA English
DT Article
DE acupuncture; adverse event; cancer pain; cervical cancer; effectiveness
ID quality-of-life; management; opioids
AB This retrospective study aimed to investigate the feasible effectiveness of acupuncture at pain acupoints for the treatment of patients with cervical cancer pain (CCP). A total of 64 cases were analyzed. All these cases were assigned to an acupuncture group or a control group according to the different therapies they received. The cases in the acupuncture group received acupuncture treatment at pain acupoints, while the subjects in the control group underwent acupuncture at regular acupoints. The primary endpoint was CCP, assessed by numeric rating scale (NRS). The secondary endpoints were evaluated by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30), and Karnofsky Performance Status (KPS). In addition, adverse events were also recorded during the treatment period. After treatment, patients in the acupuncture group exerted greater outcomes in CCP reduction when compared with patients in the control group (P<.01). In addition, no adverse events were recorded in either group. The results of this study showed that acupuncture at pain acupoints might be efficacious in patients with CCP after 14-day treatment.
C1 [Meng, Fan-feng; Feng, Yan-hong] Shaanxi Univ Chinese Med, Affiliated Hosp 2, Dept Gynecol & Obstet, 5 Weiyang West Rd, Xianyang 712000, Peoples R China.
C3 Shaanxi University of Chinese Medicine
RP Feng, YH (corresponding author), Shaanxi Univ Chinese Med, Affiliated Hosp 2, Dept Gynecol & Obstet, 5 Weiyang West Rd, Xianyang 712000, Peoples R China.
EM 50448538@qq.com
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NR 30
TC 9
Z9 10
U1 1
U2 12
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD DEC 15
PY 2018
VL 97
IS 52
BP 
EP 
DI 10.1097/MD.0000000000013736
PG 4
WC Medicine, General & Internal
SC General & Internal Medicine
GA HI3HD
UT WOS:000456338700024
PM 30593148
DA 2026-01-16
ER

PT J
AU Deng, G
   Bao, T
   Mao, JJ
AF Deng, Gary
   Bao, Ting
   Mao, Jun J.
TI Understanding the Benefits of Acupuncture Treatment for Cancer Pain Management
SO ONCOLOGY-NEW YORK
LA English
DT Article
ID induced peripheral neuropathy; clinical-practice guidelines; breast-cancer; american society; chemotherapy; trial; electroacupuncture; metaanalysis; arthralgia; prevention
AB This article summarizes the current evidence regarding the use of acupuncture for pain management in cancer patients. It includes a description of how acupuncture is thought to work and what the intervention entails, data on acupuncture for managing pain caused by cancer or by cancer treatment (radiation, chemotherapy, endocrine therapy), how acupuncture is practiced in the US medical system, discussion of safety issues, and practical tips on how to integrate acupuncture into cancer care.
C1 [Deng, Gary; Mao, Jun J.] Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1429 First Ave, New York, NY 10017 USA.
   [Bao, Ting] Mem Sloan Kettering Canc Ctr, Integrat Breast Oncol, 1275 York Ave, New York, NY 10021 USA.
C3 Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center
RP Deng, G (corresponding author), Mem Sloan Kettering Canc Ctr, Integrat Med Serv, 1429 First Ave, New York, NY 10017 USA.
EM dengg@mskcc.org
FU National Institutes of Health/National Cancer Institute Cancer Center [P30 CA008748]; National Cancer Institute [P30CA008748] Funding Source: NIH RePORTER
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NR 43
TC 22
Z9 24
U1 0
U2 23
PU UBM MEDICA
PI NORWALK
PA 535 CONNECTICUT AVE, STE 300, NORWALK, CT 06854 USA
SN 0890-9091
EI 
J9 ONCOLOGY-NY
JI Oncology-NY
PD JUN 15
PY 2018
VL 32
IS 6
BP 310
EP 316
DI 
PG 7
WC Oncology
SC Oncology
GA GJ7RG
UT WOS:000435586000009
PM 29940063
DA 2026-01-16
ER

PT J
AU Li, SS
   Tu, WZ
   Jia, CQ
   Jiang, X
   Qian, XR
   Yang, GH
   Hu, QM
   Chen, WC
   Lu, B
   Jiang, SH
AF Li, Si-Si
   Tu, Wen-Zhan
   Jia, Cheng-Qian
   Jiang, Xia
   Qian, Xin-Ru
   Yang, Guan-Hu
   Hu, Qi-Miao
   Chen, Wen-Ci
   Lu, Bin
   Jiang, Song-He
TI KCC2-GABAA pathway correlates with the analgesic effect of electro-acupuncture in CCI rats
SO MOLECULAR MEDICINE REPORTS
LA English
DT Article
DE electro-acupuncture; KCC2; GABAA receptor; chronic constriction injury; analgesic
ID cation-chloride-cotransporters; central-nervous-system; tumor-necrosis-factor; gaba-a-receptor; neuropathic pain; gene-expression; anion gradient; dorsal-horn; neurons; mechanisms
AB Potassium-chloride cotransporter 2 (KCC2) has been indicated to serve a crucial role during chronic neuropathic pain (NP). Following the emergence of NP, gamma-aminobutyric acid (GABA) A receptor-mediated signaling may be further impaired by the changes of KCC2 chloride anion gradient. In the present study, the authors investigate the effect of electro-acupuncture (EA) on the behavior and the expression of KCC2 and GABAA receptor gamma(2) subunit in the spinal cord of chronic constriction injury (CCI) model rats. A total of 60 adult male Sprague-Dawley rats were divided into four groups: Normal group, sham-CCI group, CCI group and CCI+EA group. The effect of EA was assessed via the values of mechanical withdrawal threshold and thermal withdrawal latency, which were significantly improved upon stimulation of the ST-36 and GB-34 acupoints. In addition, a marked reduction in both the mRNA and protein levels of KCC2 and GABAA receptor gamma(2) subunit was observed in the spinal cord following loose ligation of the sciatic nerve. The reductions in KCC2 and GABAA receptor gamma(2) subunit expression were reversed by EA treatment. These results support the notion that KCC2 and GABAA receptor gamma(2) subunit contribute to NP following peripheral nerve injury and extend the understanding of the analgesic effects of EA on NP.
C1 [Li, Si-Si; Tu, Wen-Zhan; Jia, Cheng-Qian; Jiang, Xia; Hu, Qi-Miao; Chen, Wen-Ci; Jiang, Song-He] Wenzhou Med Univ, Dept Phys Med & Rehabil, Affiliated Hosp 2, 268 Xueyuanxi Rd, Wenzhou 325027, Zhejiang, Peoples R China.
   [Li, Si-Si; Tu, Wen-Zhan; Jia, Cheng-Qian; Jiang, Xia; Hu, Qi-Miao; Chen, Wen-Ci; Jiang, Song-He] Wenzhou Med Univ, Yuying Childrens Hosp, 268 Xueyuanxi Rd, Wenzhou 325027, Zhejiang, Peoples R China.
   [Tu, Wen-Zhan; Qian, Xin-Ru; Yang, Guan-Hu; Jiang, Song-He] Wenzhou Med Univ, Integrat & Optimized Med Res Ctr, China US Inst Acupuncture & Rehabil, Wenzhou 325027, Zhejiang, Peoples R China.
   [Qian, Xin-Ru] NYU, Langone Med Ctr, Dept Rehabil, 550 1St Ave, New York, NY 10016 USA.
   [Yang, Guan-Hu] Ohio Univ, Dept Specialty Med, Athens, OH 45701 USA.
   [Lu, Bin] Wenzhou Med Univ, Sch Life Sci, Attardi Inst Mitochondrial Biomed, Prot Qual Control & Dis Lab, Wenzhou 325035, Zhejiang, Peoples R China.
C3 Wenzhou Medical University; Wenzhou Medical University; Wenzhou Medical University; NYU Langone Medical Center; New York University; University System of Ohio; Ohio University; Wenzhou Medical University
RP Jiang, SH (corresponding author), Wenzhou Med Univ, Dept Phys Med & Rehabil, Affiliated Hosp 2, 268 Xueyuanxi Rd, Wenzhou 325027, Zhejiang, Peoples R China.; Jiang, SH (corresponding author), Wenzhou Med Univ, Yuying Childrens Hosp, 268 Xueyuanxi Rd, Wenzhou 325027, Zhejiang, Peoples R China.; Lu, B (corresponding author), Wenzhou Med Univ, Sch Life Sci, Attardi Inst Mitochondrial Biomed, Prot Qual Control & Dis Lab, Wenzhou 325035, Zhejiang, Peoples R China.
EM lubmito@wmu.edu.cn; songhe.jiang@gmail.com
FU Natural Science Foundation of Zhejiang Province [LY16H270016]; Foundation of Wenzhou Scientific and Technological Bureau Project [Y20140221]
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NR 37
TC 19
Z9 22
U1 0
U2 10
PU SPANDIDOS PUBL LTD
PI ATHENS
PA POB 18179, ATHENS, 116 10, GREECE
SN 1791-2997
EI 1791-3004
J9 MOL MED REP
JI Mol. Med. Rep.
PD MAY 15
PY 2018
VL 17
IS 5
BP 6961
EP 6968
DI 10.3892/mmr.2018.8766
PG 8
WC Oncology; Medicine, Research & Experimental
SC Oncology; Research & Experimental Medicine
GA GD5OR
UT WOS:000430556800096
PM 29568893
DA 2026-01-16
ER

PT J
AU Ko, MM
   Jang, S
   Lee, JA
   Kang, BK
   Jung, J
AF Ko, Mi Mi
   Jang, Soobin
   Lee, Ju Ah
   Kang, Byung Kab
   Jung, Jeeyoun
TI Blood Stasis Therapy for Traumatic Injury: A Prospective, Single-Arm, Pre-Post
SO Journal of alternative and complementary medicine (New York, N.Y.)
LA English
DT Journal Article
DE Traditional Korean Medicine; blood stasis; diagnosis; pain; perfusion index; traumatic injury
AB OBJECTIVES: Blood stasis is an important pathophysiologic concept in Traditional  East Asian Medicine. It has been considered to be a pathogenic factor in chronic  and incurable conditions such as pain, infertility, cancer, coronary heart  disease, and others. The aim of this study was to investigate the effects of pain  reduction by blood stasis treatment for blood stasis syndromes with traumatic  injury. METHODS: A single-center prospective pretest-post-test pilot study  included 73 patients with a trauma that occurred within the past 2 weeks who were  admitted into Jaseng Hospital of Korean Medicine from August 2015 through  December 2015. Of the 50 patients analyzed in this study, 42 were women (mean  age, 33.52). Triple Energizer-reinforcing Saam acupuncture set, herbal medicine  (Dangkwisoo-san), and wet cupping on tender point, which are Korean medical  therapies generally executed to treat post-traumatic pain, were performed. The  patients had to receive at least six sessions of treatment during the 2 weeks,  with subsequent treatment being performed within 3 ± 1 days after the previous  treatment. Numeric rating scale (NRS) score and general pain severity indicator  was measured as a primary outcome measure. The blood stasis questionnaire,  oximetry, and patient's satisfaction were also measured. RESULTS: The mean size  of subcutaneous bleeding (width and length) and NRS score as a general pain  indicator significantly decreased over the visits (all p < 0.01, visit 1 vs.  visit 6). Among the blood stasis symptoms in the questionnaire, 11 blood stasis  indicators significantly decreased (all p < 0.05). The patients showed  significant improvement in the minimum and maximum value of peripheral perfusion  index after the treatment (p = 0.011 and p = 0.15, respectively). CONCLUSIONS:  This study reveals that blood stasis treatment may help improve the pain of  patients with traumatic injury by enhancing the peripheral blood flow. The  significant results observed in this study support some evidence of the theories  of diagnosing blood stasis pattern and treatments of that pattern in Korean  Medicine.
C1 1 Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
   1 Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
   2 Department of Korean Internal Medicine, College of Korean Medicine, Gachon University, Seongnam, Republic of Korea.
   1 Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
   1 Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
NR 0
TC 0
SN 1557-770
EI 
J9 J Altern Complement Med
PD AUG 30
PY 2018
VL 25
IS 3
BP 359
EP 365
DI 10.1089/acm.2018.0134
PG 6
WC Acupuncture Therapy; Adult; Contusions; therapy; Female; Humans; Male; Medicine, Korean Traditional; methods; Pain Management; methods; Pilot Projects; Plant Preparations; therapeutic use; Prospective Studies; Treatment Outcome; Wounds and Injuries; therapy; Young Adult
UT PubMed:30156424
PM 30156424
DA 2018-08-30
ER

PT J
AU Cheon, S
   Lee, H
AF Cheon, Soyeon
   Lee, Hyangsook
TI Correspondence regarding Anshasi and Ahmad's "an assessment of methodological quality of systematic reviews of acupuncture and related therapies for cancer-related pain" in complement ther clin pract 2018 August
SO COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
LA English
DT Letter
DE Pharmacopuncture; Acupoint injection; Acupuncture; Cancer
C1 [Cheon, Soyeon; Lee, Hyangsook] Kyung Hee Univ, Coll Korean Med, Acupuncture & Meridian Sci Res Ctr, Kyung Hee Dae Ro 26, Seoul 02447, South Korea.
   [Cheon, Soyeon] Natl Cheng Kung Univ, Coll Med, Dept Publ Hlth, Tainan 70101, Taiwan.
C3 Kyung Hee University; National Cheng Kung University
RP Lee, H (corresponding author), Kyung Hee Univ, Coll Korean Med, Acupuncture & Meridian Sci Res Ctr, Kyung Hee Dae Ro 26, Seoul 02447, South Korea.
EM erc633@khu.ac.kr
CR Anshasi HA, 2018, COMPLEMENT THER CLIN, V32, P163, DOI 10.1016/j.ctcp.2018.06.013
   Cheon S, 2014, EVID-BASED COMPL ALT, V2014, P0, DOI 10.1155/2014/804746
   Choi TY, 2012, SUPPORT CARE CANCER, V20, P1147, DOI 10.1007/s00520-012-1432-9
   Jergas H, 2015, PEERJ, V3, P0, DOI 10.7717/peerj.1364
NR 4
TC 1
Z9 1
U1 0
U2 6
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1744-3881
EI 1873-6947
J9 COMPLEMENT THER CLIN
JI Complement. Ther. Clin. Pract.
PD NOV 15
PY 2018
VL 33
IS 
BP 138
EP 138
DI 10.1016/j.ctcp.2018.09.008
PG 1
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA GZ2GW
UT WOS:000449198200019
PM 30396611
DA 2026-01-16
ER

PT J
AU Sand-Jecklin, K
   Reiser, V
AF Sand-Jecklin, Kari
   Reiser, Victoria
TI Use of Seva Stress Release Acupressure to Reduce Pain, Stress, and Fatigue in
SO Journal of hospice and palliative nursing : JHPN : the official journal of the
LA English
DT Journal Article
AB Patients undergoing treatment for cancer often experience stress, fatigue, and  pain during their treatment. Medical management of these symptoms can cause  additional adverse effects, but it is possible that noninvasive complementary  therapies may be able to reduce these symptoms without unwanted adverse effects.  The purpose of this study was to assess the feasibility and impact of the Seva  Stress Release acupressure protocol on stress, fatigue, pain, and vital signs of  patients hospitalized for cancer treatment. Thirty patients receiving cancer  treatment and experiencing stress, fatigue, and pain were recruited for the  study. After obtaining informed consent, baseline data (survey and vital signs)  were obtained, followed by administration of the Seva Stress Release. After the  intervention, vital signs were obtained, and patients completed 2 additional  surveys. After Seva, patient stress, fatigue, pain, heart rate, and respirations  were significantly decreased (P = .000). Sixty-six percent of participants  experienced symptom relief for at least 1 to 4 hours. Qualitative findings also  indicated that patients reported better sleep and mental clarity after the  intervention. The Seva protocol could be taught to nurses and be used as an  independent intervention for patients experiencing adverse effects of cancer  treatment, to promote comfort and reduce stress and fatigue.
C1 Kari Sand-Jecklin, EdD, MSN, RN, AHN-BC, is associate professor, West Virginia University School of Nursing, Morgantown. Victoria Reiser, BSN, RN, is DNPstudent, University of Pittsburgh School of Nursing, Pennsylvania.
NR 0
TC 0
SN 1539-070
EI 
J9 J Hosp Palliat Nurs
PD NOV 1
PY 2018
VL 20
IS 6
BP 521
EP 528
DI 10.1097/NJH.0000000000000484
PG 7
WC Acupressure; methods; Adult; Aged; Aged, 80 and over; Fatigue; psychology; Female; Hospitalization; statistics & numerical data; Humans; Male; Middle Aged; Neoplasms; complications; Pain; complications; Pain Management; methods; Pilot Projects; Stress, Psychological; psychology
UT PubMed:30379796
PM 30379796
DA 2018-11-01
ER

PT J
AU Liang, Y
   Du, JY
   Fang, JF
   Fang, RY
   Zhou, J
   Shao, XM
   Jiang, YL
   Chen, YT
   Fang, JQ
AF Liang, Yi
   Du, Jun-Ying
   Fang, Jun-Fan
   Fang, Ruo-Yi
   Zhou, Jie
   Shao, Xiao-Mei
   Jiang, Yong-Liang
   Chen, Yi-Tian
   Fang, Jian-Qiao
TI Alleviating Mechanical Allodynia and Modulating Cellular Immunity Contribute to Electroacupuncture's Dual Effect on Bone Cancer Pain
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE bone cancer pain; electroacupuncture; morphine; analgesia; mechanical allodynia; cellular immunity; naloxone
ID peripheral opioid receptors; rat model; morphine; acupuncture; expression; analgesia; activation; cells
AB Hypothesis: Electroacupuncture (EA) has been used as an alternative analgesic therapy for hundreds of years, yet its analgesic potency and therapeutic advantage against bone cancer pain (BCP) in comparison with morphine remains unclear. This study aimed to investigate the effects of EA on mechanical allodynia and cellular immunity of BCP rats, and to further explore the potential mechanism. Methods: The BCP model was established by implanting Walker 256 mammary gland carcinoma cells into the left tibia of adult female Sprague-Dawley rats. EA (dilatational wave, 2/100 Hz, 0.5 mA-1mA-1.5 mA for 10 minutes each intensity) was applied bilaterally to Zusanli (ST 36) and Kunlun (BL 60) for 30 minutes. Both EA stimulation and morphine (10 mg/kg, intraperitoneally) was given once every other day. Naloxone (0.3 mg/kg, intraperitoneally) was injected at 30 minutes prior to EA. Mechanical allodynia were demonstrated by paw withdrawal thresholds (PWTs) which measured by dynamic plantar aesthesiometer. T cell proliferation, percentage of CD3(+), CD4(+) and CD8(+) T lymphocytes in spleen as well as expression of interleukin-2 (IL-2) in plasma were detected by WST-8, flow cytometry, and enzyme-linked immunosorbent assay technique, respectively. Results: An intratibial inoculation of Walker 256 mammary gland carcinoma cells significantly decreased PWTs to mechanical stimuli. EA stimulation alleviated mechanical allodynia in BCP rats, and the analgesic potency of EA was weaker than that of morphine. In contrast to morphine, EA stimulation of BCP rats increased splenic concanavalin A (Con A)-induced T cell proliferation and plasma IL-2 content, as well as increased the percentages of splenic CD3+CD4+ and CD3+CD8+ T cell subsets. Moreover, both the analgesic effect and the partial immunomodulation of EA were suppressed by an intraperitoneal injection of naloxone. Conclusion: EA could significantly alleviate BCP-induced mechanical allodynia. Although the analgesic effect of EA was weaker than that of morphine, EA had an immunomodulation effect on cellular immunity. Both analgesic and immunomodulatory effect of EA might share the same mechanism via the opioid-mediated pathway, which needs further investigation.
C1 [Liang, Yi; Du, Jun-Ying; Fang, Jun-Fan; Fang, Ruo-Yi; Shao, Xiao-Mei; Jiang, Yong-Liang; Chen, Yi-Tian; Fang, Jian-Qiao] Zhejiang Chinese Med Univ, Clin Med Coll 3, Hangzhou, Zhejiang, Peoples R China.
   [Liang, Yi; Zhou, Jie] Zhejiang Chinese Med Univ, Affiliated Hosp 3, Hangzhou, Zhejiang, Peoples R China.
C3 Zhejiang Chinese Medical University; Zhejiang Chinese Medical University
RP Fang, JQ (corresponding author), Zhejiang Chinese Med Univ, Clin Med Coll 3, Dept Neurobiol & Acupuncture Res, 548 Binwen Rd, Hangzhou 310053, Zhejiang, Peoples R China.
EM fangjianqiao7532@163.com
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NR 43
TC 19
Z9 25
U1 1
U2 23
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD JUN 15
PY 2018
VL 17
IS 2
BP 401
EP 410
DI 10.1177/1534735417728335
PG 10
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA GF6JS
UT WOS:000432073700025
PM 28870114
DA 2026-01-16
ER

PT J
AU Zhu, HD
   Gong, Z
   Hu, BW
   Wei, QL
   Kong, J
   Peng, CB
AF Zhu, Hua-dong
   Gong, Zhen
   Hu, Bing-wei
   Wei, Qiao-ling
   Kong, Jun
   Peng, Cong-bin
TI The Efficacy and Safety of Transcutaneous Acupoint Interferential Current Stimulation for Cancer Pain Patients With Opioid-Induced Constipation: A Prospective Randomized Controlled Study
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE opioid-induced constipation; lactulose; transcutaneous acupoint interferential current therapy; cancer pain; quality of life
ID electrical-stimulation; bowel dysfunction; prevalence; trial; management; conduction; therapy; burden; impact; adults
AB Introduction. Opioid-induced constipation (OIC) is a principal complication secondary to analgesic therapy for cancer pain patients who suffer moderate to severe pain. In this study, we observe the efficacy and safety of transcutaneous acupoint interferential current (IFC) stimulation in those patients with OIC. Methods. A total of 198 patients were randomly allocated to the IFC group and control group in a 1:1 ratio. Finally, 98 patients in the IFC group received 14 sessions administered over 2 weeks, whereas 100 patients in the control group took lactulose orally during the same period. Observation items were documented at management stage and at follow-up stage according to Cleveland Constipation Scales (CCS), pain Numeric Rating Scales (NRS) and Patient Assessment of Constipation Quality of Life (PAC-QoL). Results. The total curative effects of the IFC group and the control group were indistinguishable (76.5% vs 70.0%, P = .299). Regarding CCS and PAC-QoL scores, no significant difference was observed between the 2 groups during the management time and at the follow-up stage of week 3 (P > .05, respectively), but groups were distinguished at the follow-up stage of week 4 (P < .001 and P = .031, respectively). The pain NRS decreased significantly at management stage week 2 and follow-up stage week 3 and week 4 (P = .013, P = .041, P = .011, respectively). Conclusions. Transcutaneous acupoint IFC therapy over acupoints of Tianshu (ST25) and Zhongwan (RN12) may improve constipation and quality of life in cancer patients receiving opiates; further studies are worthwhile.
C1 [Zhu, Hua-dong; Gong, Zhen; Hu, Bing-wei; Wei, Qiao-ling; Kong, Jun; Peng, Cong-bin] Tongde Hosp Zhejiang Prov, Hangzhou, Zhejiang, Peoples R China.
RP Kong, J (corresponding author), Tongde Hosp Zhejiang Prov, Dept Neurosurg, 234 Gucui Rd, Hangzhou 310012, Zhejiang, Peoples R China.
EM kongjfj@163.com
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NR 37
TC 8
Z9 11
U1 2
U2 11
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD JUN 15
PY 2018
VL 17
IS 2
BP 437
EP 443
DI 10.1177/1534735417734910
PG 7
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA GF6JS
UT WOS:000432073700029
PM 29076387
DA 2026-01-16
ER

